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  1. Book ; Online: Innovative medicine

    Nakao, Kazuwa / Minato, Nagahiro / Uemoto, Shinji

    basic research and development

    (Springer open)

    2015  

    Author's details Ed.: Kazuwa Nakao, Nagahiro Minato, Shinji Uemoto
    Series title Springer open
    Language English
    Publisher Springer
    Publishing place Tokyo u.a.
    Publishing country Japan
    Document type Book ; Online
    HBZ-ID HT018810738
    ISBN 978-4-431-55651-0 ; 978-4-431-55650-3 ; 4-431-55651-6 ; 4-431-55650-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Innovative Medicine

    Nakao, Kazuwa / Minato, Nagahiro / Uemoto, Shinji

    Basic Research and Development

    2015  

    Author's details edited by Kazuwa Nakao, Nagahiro Minato, Shinji Uemoto
    Keywords Medicine ; Immunology ; Molecular biology ; Cell biology
    Subject code 611.01816
    Language English
    Size 1 Online-Ressource (IX, 339 p. 105 illus., 90 illus. in color)
    Edition 1st ed. 2015
    Publisher Springer Japan ; Imprint: Springer
    Publishing place Tokyo
    Document type Book ; Online
    HBZ-ID HT018836499
    ISBN 978-4-431-55651-0 ; 9784431556503 ; 4-431-55651-6 ; 4431556508
    DOI 10.1007/978-4-431-55651-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: Innovative Medicine: Basic Research and Development

    Nakao, Kazuwa / Minato, Nagahiro / Uemoto, Shinji

    2015  

    Keywords Medicine ; molecular medicine ; immunology ; cell biology
    Size 1 electronic resource (339 pages)
    Publisher Springer Nature
    Publishing place Cham
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021028953
    ISBN 9784431556510 ; 4431556516
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article: Editorial: The impact of alkalizing the acidic tumor microenvironment to improve efficacy of cancer treatment.

    Hamaguchi, Reo / Uemoto, Shinji / Wada, Hiromi

    Frontiers in oncology

    2023  Volume 13, Page(s) 1223025

    Language English
    Publishing date 2023-05-31
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1223025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Diverse antitumor effects of ascorbic acid on cancer cells and the tumor microenvironment.

    Maekawa, Takeru / Miyake, Toru / Tani, Masaji / Uemoto, Shinji

    Frontiers in oncology

    2022  Volume 12, Page(s) 981547

    Abstract: Ascorbic acid has attracted substantial attention for its potential antitumor effects by acting as an ... ...

    Abstract Ascorbic acid has attracted substantial attention for its potential antitumor effects by acting as an antioxidant
    Language English
    Publishing date 2022-09-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.981547
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Best practices in liver transplantation for hepatocellular carcinoma].

    Uemoto, Shinji

    Nihon Shokakibyo Gakkai zasshi The Japanese journal of gastro-enterology

    2014  Volume 111, Issue 5, Page(s) 875–879

    MeSH term(s) Carcinoma, Hepatocellular/surgery ; Humans ; Insurance, Health ; Japan ; Liver Neoplasms/surgery ; Liver Transplantation/economics ; Prognosis
    Language Japanese
    Publishing date 2014-05-07
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 708695-7
    ISSN 1349-7693 ; 0446-6586
    ISSN (online) 1349-7693
    ISSN 0446-6586
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Reply to: "Predicted Volume or Actual Weight for Graft Selection Policy in Living-donor Liver Transplantation".

    Kusakabe, Jiro / Yagi, Shintaro / Uemoto, Shinji

    Transplantation

    2021  Volume 105, Issue 4, Page(s) e44–e45

    MeSH term(s) Graft Survival ; Humans ; Liver ; Liver Transplantation ; Living Donors ; Policy
    Language English
    Publishing date 2021-10-01
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000003584
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Occult bacteremia in living donor liver transplantation: a prospective observational study of recipients and donors.

    Yao, Siyuan / Yagi, Shintaro / Sugimoto, Takuya / Asahara, Takashi / Uemoto, Shinji / Hatano, Etsuro

    Surgery today

    2023  Volume 54, Issue 6, Page(s) 596–605

    Abstract: Purpose: To investigate the incidence and clinical impact of occult bacteremia in liver transplantation (LT).: Methods: This prospective observational study involved a fixed-point observation for up to 2 weeks after living donor LT in 20 recipients, ... ...

    Abstract Purpose: To investigate the incidence and clinical impact of occult bacteremia in liver transplantation (LT).
    Methods: This prospective observational study involved a fixed-point observation for up to 2 weeks after living donor LT in 20 recipients, with 20 donors as comparison subjects. Bacteria in the blood samples were detected using the ribosomal RNA-targeted reverse-transcription quantitative polymerase chain reaction method. To identify the causality with the gut microbiota (GM), fecal samples were collected and analyzed simultaneously.
    Results: Occult bacteremia was identified in four recipients (20%) and three donors (15%) before the operation, and in seven recipients (35%) and five donors (25%) after the operation. Clostridium leptum subgroup, Prevotella, Colinesella, Enterobacteriaceae, and Streptococcus were the main pathogens responsible. Although it did not negatively affect the donor post-hepatectomy outcomes, the recipients with occult bacteremia had a higher rate of infectious complications post-LT. The GM analyses showed fewer post-LT predominant obligate anaerobes in both the recipients and donors with occult bacteremia.
    Conclusions: Occult bacteremia is a common condition that occurs in both donors and recipients. While occult bacteremia generally remains subclinical in the healthy population, there is potential risk of the development of an apparent post-LT infection in recipients who are highly immunosuppressed.
    MeSH term(s) Humans ; Liver Transplantation/adverse effects ; Living Donors ; Bacteremia/epidemiology ; Bacteremia/etiology ; Bacteremia/microbiology ; Prospective Studies ; Male ; Female ; Middle Aged ; Adult ; Postoperative Complications/microbiology ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Incidence ; Gastrointestinal Microbiome ; Aged ; Feces/microbiology
    Language English
    Publishing date 2023-12-10
    Publishing country Japan
    Document type Journal Article ; Observational Study
    ZDB-ID 1115435-4
    ISSN 1436-2813 ; 0941-1291
    ISSN (online) 1436-2813
    ISSN 0941-1291
    DOI 10.1007/s00595-023-02778-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: ASO Author Reflections: Recurrence Type of NEN Around the Head of the Pancreas.

    Masui, Toshihiko / Uemoto, Shinji

    Annals of surgical oncology

    2018  Volume 25, Issue Suppl 3, Page(s) 812–813

    MeSH term(s) Duodenal Neoplasms ; Humans ; Neoplasm Recurrence, Local ; Neuroendocrine Tumors ; Pancreas
    Language English
    Publishing date 2018-10-12
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-018-6875-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Liver Regeneration after Hepatectomy and Partial Liver Transplantation.

    Yagi, Shintaro / Hirata, Masaaki / Miyachi, Yosuke / Uemoto, Shinji

    International journal of molecular sciences

    2020  Volume 21, Issue 21

    Abstract: The liver is a unique organ with an abundant regenerative capacity. Therefore, partial hepatectomy (PHx) or partial liver transplantation (PLTx) can be safely performed. Liver regeneration involves a complex network of numerous hepatotropic factors, ... ...

    Abstract The liver is a unique organ with an abundant regenerative capacity. Therefore, partial hepatectomy (PHx) or partial liver transplantation (PLTx) can be safely performed. Liver regeneration involves a complex network of numerous hepatotropic factors, cytokines, pathways, and transcriptional factors. Compared with liver regeneration after a viral- or drug-induced liver injury, that of post-PHx or -PLTx has several distinct features, such as hemodynamic changes in portal venous flow or pressure, tissue ischemia/hypoxia, and hemostasis/platelet activation. Although some of these changes also occur during liver regeneration after a viral- or drug-induced liver injury, they are more abrupt and drastic following PHx or PLTx, and can thus be the main trigger and driving force of liver regeneration. In this review, we first provide an overview of the molecular biology of liver regeneration post-PHx and -PLTx. Subsequently, we summarize some clinical conditions that negatively, or sometimes positively, interfere with liver regeneration after PHx or PLTx, such as marginal livers including aged or fatty liver and the influence of immunosuppression.
    MeSH term(s) Animals ; Fatty Liver/physiopathology ; Hepatectomy/methods ; Humans ; Liver/physiology ; Liver Regeneration/physiology ; Liver Transplantation/methods
    Language English
    Publishing date 2020-11-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms21218414
    Database MEDical Literature Analysis and Retrieval System OnLINE

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