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  1. Article: Reponse on Muhammad Bilal, et al. (J Pak Med Assoc. 72, No-5: 839- 842, 2022) Efficacy of rituximab in patients with rheumatoid arthritis.

    Bilal, Muhammad / Ullah, Ansar / Khattak, Saima

    JPMA. The Journal of the Pakistan Medical Association

    2023  Volume 73, Issue 5, Page(s) 1157

    MeSH term(s) Humans ; Rituximab/therapeutic use ; Arthritis, Rheumatoid/drug therapy
    Chemical Substances Rituximab (4F4X42SYQ6)
    Language English
    Publishing date 2023-05-12
    Publishing country Pakistan
    Document type Letter ; Comment
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Efficacy of rituximab in patients with rheumatoid arthritis.

    Bilal, Muhammad / Ullah, Ansar / Khattak, Saima

    JPMA. The Journal of the Pakistan Medical Association

    2022  Volume 72, Issue 5, Page(s) 839–842

    Abstract: Objective: To determine the efficacy of rituximab 2×500mg in rheumatoid arthritis patients.: Methods: The descriptive case series was conducted at the Department of General Medicine, Lady Reading Hospital, Peshawar, Pakistan, from November 25, 2018, ... ...

    Abstract Objective: To determine the efficacy of rituximab 2×500mg in rheumatoid arthritis patients.
    Methods: The descriptive case series was conducted at the Department of General Medicine, Lady Reading Hospital, Peshawar, Pakistan, from November 25, 2018, to May 24, 2019, and comprised patients of either gender aged 30-60 years with rheumatoid arthritis diagnosis for >6 months. The patients received 2 doses of rituximab 2×500mg through intravenous infusion with pre-medications as a standard protocol. A follow-up visit was recommended for each patient after 24 weeks. The efficacy of the treatment in terms of disease progression and improvement were observed using the Disease Activity Score-28 scale at the baseline and on follow-up. Data was analysed using SPSS 20.
    Results: Of the 97 patients, 83(85.6%) were female and 14(14.4%) were male. The overall mean age was 50.68±14.27 years. The baseline score was 6.68±1.14 while the follow-up score was 4.62±0.93 (p<0.05). In terms of efficacy, 25(25.8%) patients showed no improvement, while 72(74.2%) had improvement.
    Conclusions: Rituximab 2×500mgI was found to be an effective treatment option for rheumatoid arthritis patients.
    MeSH term(s) Adult ; Aged ; Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/drug therapy ; Disease Progression ; Female ; Humans ; Male ; Middle Aged ; Rituximab/therapeutic use ; Treatment Outcome
    Chemical Substances Antirheumatic Agents ; Rituximab (4F4X42SYQ6)
    Language English
    Publishing date 2022-06-16
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.47391/JPMA.01373
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The Prevalence of Incidentally Detected Urolithiasis in Subjects Undergoing Computerized Tomography.

    Saeed, Sajeel / Ullah, Ansar / Ahmad, Jawad / Hamid, Sidra

    Cureus

    2020  Volume 12, Issue 9, Page(s) e10374

    Abstract: Background and objective Urolithiasis is defined as the presence of calculi in the urinary tract. Multiple studies have shown that urinary tract stones are one of the most common incidental findings in medical imaging. These stones are potentially ... ...

    Abstract Background and objective Urolithiasis is defined as the presence of calculi in the urinary tract. Multiple studies have shown that urinary tract stones are one of the most common incidental findings in medical imaging. These stones are potentially dangerous and can cause severe impairment to renal function if they remain undiagnosed for a long time. The objective of this study was to determine the prevalence of incidentally detected urolithiasis in patients undergoing abdominopelvic CT scans. Materials and methods A retrospective cross-sectional study was conducted, which involved 721 patients selected by consecutive non-randomized sampling. The study population included patients who underwent an abdominopelvic CT scan in the radiology department of a tertiary care hospital in Pakistan. Patients aged below 10 years and those above 90 years were excluded from the study. Patients undergoing kidney, ureter, and bladder (KUB) scan for urolithiasis-associated symptoms and those with already known urolithiasis were also excluded. The data were recorded in a predesigned pro forma and analyzed with SPSS Statistics version 20.00 (IBM, Armonk, NY). Results A total of 721 patients underwent an abdominopelvic CT scan during the six months from July to December in the radiology department of the hospital. Out of these, 336 (46.6%) were males, and 385 (53.4%) were females. Incidental stones were found in 20 of these patients. Among these 20 stone formers, 11 were males, and nine were females. Out of them, six had stones in the right kidney, eight in the left kidney, and four patients had bilateral stones. The remaining two patients had stones in their ureters. In most cases, stones were found in lower poles as compared to the mid pole and upper pole of the kidneys. Conclusion The prevalence of incidentally detected urolithiasis was found to be 2.8% in this study. Its frequency was much higher in males (3.27%) compared to females (2.33%). Most of the stones were found in the kidneys whereas no stone was detected in the urinary bladder.
    Language English
    Publishing date 2020-09-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.10374
    Database MEDical Literature Analysis and Retrieval System OnLINE

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