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  1. Article ; Online: Female genital schistosomiasis mimicking an ovarian neoplasm: A case report.

    Muhammad, Ibrahim Danladi / Umar, Usman Aliyu / Sabo, Umar Suleiman / Rabiu, Ibrahim / Ahmad, Abdullahi Muhammad / Yusuf, Mustapha Ahmed

    Parasitology international

    2024  Volume 101, Page(s) 102878

    Abstract: Objective: A case description of a rare occurrence of female genital schistosomiasis affecting the upper genital tract that presented with features mimicking an ovarian neoplasm.: Case report: Female genital schistosomiasis is a neglected clinical ... ...

    Abstract Objective: A case description of a rare occurrence of female genital schistosomiasis affecting the upper genital tract that presented with features mimicking an ovarian neoplasm.
    Case report: Female genital schistosomiasis is a neglected clinical manifestation of the water-born parasitic disease which occurs due to the presence of schistosome eggs in the genitalia of women. A 23-year-old nulliparous woman presented with progressive abdominal distension. An abdominopelvic CT scan revealed a multilobulated right adnexal mass with gross ascites. Diagnosis of schistosomiasis was made by histology of biopsied specimens following laparotomy. Cervical colposcopic findings were consistent with female genital schistosomiasis. She was successfully treated with praziquantel.
    Conclusion: Female genital schistosomiasis of the upper genital tract can mimic an ovarian malignancy. Hence there is a need for its consideration as a differential diagnosis in patients with non-classical presentations of pelvic tumours in schistosomiasis-endemic areas.
    Language English
    Publishing date 2024-03-05
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 1363151-2
    ISSN 1873-0329 ; 1383-5769
    ISSN (online) 1873-0329
    ISSN 1383-5769
    DOI 10.1016/j.parint.2024.102878
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effectiveness of preoperative tranexamic acid in reducing blood loss during caesarean section at Aminu Kano Teaching Hospital, Kano: a randomized controlled trial.

    Oseni, Rasaki Olaiya / Zakari, Mohammad / Adamou, Natalia / Umar, Usman Aliyu

    The Pan African medical journal

    2021  Volume 39, Page(s) 34

    Abstract: Introduction: bleeding during and after caesarean section is one of the contributors to maternal mortality and morbidity. Tranexamic acid can be given before surgery to significantly reduce the amount of blood loss during caesarean section. The ... ...

    Abstract Introduction: bleeding during and after caesarean section is one of the contributors to maternal mortality and morbidity. Tranexamic acid can be given before surgery to significantly reduce the amount of blood loss during caesarean section. The objective was to evaluate the effectiveness of preoperative tranexamic acid in reducing blood loss during caesarean section at Aminu Kano Teaching Hospital, Kano.
    Methods: this was a randomized double blind placebo controlled study that was carried out among 244 women who were to have emergency caesarean section between December 2017 and June 2018 and were randomly assigned to the study group or control group. Women in the study group received lg (10mls) of tranexamic acid intravenously while women in the control group received 10ml of normal saline. Oxytocin was administered in the two groups according to protocol. Measurement of blood loss was done immediately after surgery. Postoperative drop in haemoglobin and haematocrit were also determined. Statistical analysis was done using SPSS Version 22.
    Results: the average intra operative blood loss was 414.0 ml in the study group and 773.8 ml in the control group (t = - 16.18, p ≤ 0.01). Average postoperative haemoglobin was 10.1 g/dl in the study group and 9.5 g/dl in the control group (t = 4.99, p ≤ 0.01). Average postoperative haematocrit was 31.5% in the study group and 29.9% in the control group (t = 4.70, p ≤ 0.01).
    Conclusion: there was a significant reduction in the blood loss when preoperative tranexamic acid was given to patients who were to undergo emergency caesarean section.
    MeSH term(s) Adult ; Antifibrinolytic Agents/administration & dosage ; Blood Loss, Surgical/prevention & control ; Cesarean Section/methods ; Double-Blind Method ; Female ; Hematocrit ; Hemoglobins ; Hospitals, Teaching ; Humans ; Nigeria ; Postpartum Hemorrhage/prevention & control ; Pregnancy ; Preoperative Care/methods ; Tranexamic Acid/administration & dosage ; Young Adult
    Chemical Substances Antifibrinolytic Agents ; Hemoglobins ; Tranexamic Acid (6T84R30KC1)
    Language English
    Publishing date 2021-05-12
    Publishing country Uganda
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2514347-5
    ISSN 1937-8688 ; 1937-8688
    ISSN (online) 1937-8688
    ISSN 1937-8688
    DOI 10.11604/pamj.2021.39.34.21938
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: An Assessment of Ovarian Cancer Histotypes Across the African Diaspora.

    George, Sophia H L / Omotoso, Ayodele / Pinto, Andre / Mustapha, Aisha / Sanchez-Covarrubias, Alex P / Umar, Usman Aliyu / Umar, Ali Bala / Oluwasola, Timothy Abiola / Okolo, Clement Abu / Anthony, Umeh Uchenna / Ukekwe, Francis Ikechukwu / Bakari, Maisaratu A / Dahiru, Aminu M C / Abdullahi, Habiba Ibrahim / Abimiku, Bawa Ahmed / Abdurrahman, Aisha / Usman, Asmau / Ahmed, Saad Aliyu / Usman, Hadiza Abdullahi /
    Kabir, Abba / Eleje, George Uchenna / Chiemeka, Michael Emeka / Nzeribe, Emily / Nweke, Ikechukwu / Kadas, SaiduAbubakar / Suleiman, Dauda E / Ekanem, Etim / Uche, Umemmuo Maureen / Paul, Jibrin / Agwu, Uzoma Maryrose / Edegbe, Felix O / Anorlu, Rose I / Banjo, Adekunbiola / Ajenifuja, Kayode Olusegun / Fawole, Adegboyega Adisa / Kazeem, Ibrahim O O / Magaji, Francis / Silas, Olugbenga / Athanasius, Boma Precious / Tamunomie, Nyengidiki Kennedy / Bassey, Emem / Abudu, Kunle / Ango, Ibrahim G / Abdullahi, Kabiru / Lawal, Ishak / Kabir, Suleiman Aliyu / Ekanem, Victor / Ezeanochie, Michael / Yahaya, Usman Rahman / Castillo, Melissa Nicole / Bahall, Vishal / Chatrani, Vikash / Brambury, Ian / Bowe, Saida / Halliday, Darron / Bruney, George / Butler, Raleigh / Ragin, Camille / Odedina, Folakemi / Chamala, Srikar / Schlumbrecht, Matthew / Audu, Bala

    Frontiers in oncology

    2021  Volume 11, Page(s) 732443

    Abstract: Objective: Ovarian cancer in Black women is common in many West African countries but is relatively rare in North America. Black women have worse survival outcomes when compared to White women. Ovarian cancer histotype, diagnosis, and age at ... ...

    Abstract Objective: Ovarian cancer in Black women is common in many West African countries but is relatively rare in North America. Black women have worse survival outcomes when compared to White women. Ovarian cancer histotype, diagnosis, and age at presentation are known prognostic factors for outcome. We sought to conduct a preliminary comparative assessment of these factors across the African diaspora.
    Methods: Patients diagnosed with ovarian cancer (all histologies) between June 2016-December 2019 in Departments of Pathology at 25 participating sites in Nigeria were identified. Comparative population-based data, inclusive of Caribbean-born Blacks (CBB) and US-born Blacks (USB), were additionally captured from the International Agency for Research on Cancer and Florida Cancer Data Systems. Histology, country of birth, and age at diagnosis data were collected and evaluated across the three subgroups: USB, CBB and Nigerians. Statistical analyses were done using chi-square and student's t-test with significance set at p<0.05.
    Results: Nigerians had the highest proportion of germ cell tumor (GCT, 11.5%) and sex-cord stromal (SCST, 16.2%) ovarian cancers relative to CBB and USB (p=0.001). CBB (79.4%) and USB (77.3%) women were diagnosed with a larger proportion of serous ovarian cancer than Nigerians (60.4%) (p<0.0001). Nigerians were diagnosed with epithelial ovarian cancers at the youngest age (51.7± 12.8 years) relative to USB (58.9 ± 15.0) and CBB (59.0± 13.0,p<0.001). Black women [CBB (25.2 ± 15.0), Nigerians (29.5 ± 15.1), and USB (33.9 ± 17.9)] were diagnosed with GCT younger than White women (35.4 ± 20.5, p=0.011). Black women [Nigerians (47.5 ± 15.9), USB (50.9 ± 18.3) and CBB (50.9 ± 18.3)] were also diagnosed with SCST younger than White women (55.6 ± 16.5, p<0.01).
    Conclusion: There is significant variation in age of diagnosis and distribution of ovarian cancer histotype/diagnosis across the African diaspora. The etiology of these findings requires further investigation.
    Language English
    Publishing date 2021-11-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2021.732443
    Database MEDical Literature Analysis and Retrieval System OnLINE

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