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  1. Book: Cardiovascular outcomes of treatments available for patients with type 1 and 2 diabetes

    Umpierrez, Guillermo E.

    (Endocrinology and metabolism clinics of North America ; volume 47, number 1 (March 2018))

    2018  

    Author's details editor Guillermo E. Umpierrez
    Series title Endocrinology and metabolism clinics of North America ; volume 47, number 1 (March 2018)
    Collection
    Language English
    Size xvi, 257 Seiten, Illustrationen
    Publisher Elsevier
    Publishing place Philadelphia, Pennsylvania
    Publishing country United States
    Document type Book
    HBZ-ID HT019646175
    ISBN 978-0-323-58397-8 ; 0-323-58397-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Se 148 -47,1- verfügbar in Königswinter Königswinter

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  2. Article ; Online: Glucose Control in the ICU.

    Umpierrez, Guillermo E

    The New England journal of medicine

    2023  Volume 389, Issue 13, Page(s) 1234–1237

    MeSH term(s) Humans ; Blood Glucose/analysis ; Intensive Care Units ; Glycemic Control/methods
    Chemical Substances Blood Glucose
    Language English
    Publishing date 2023-09-08
    Publishing country United States
    Document type Editorial
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMe2309442
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Letter to the Editor From Tayek and Umpierrez: "New Onset or Stress Hyperglycemia and Hospital Mortality Risk".

    Tayek, John A / Umpierrez, Guillermo E

    The Journal of clinical endocrinology and metabolism

    2023  Volume 109, Issue 4, Page(s) e1367

    MeSH term(s) Humans ; Hospital Mortality ; Hyperglycemia
    Language English
    Publishing date 2023-11-22
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/clinem/dgad679
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  4. Article ; Online: Beyond pounds: What else could be lost?

    Idrees, Thaer / Umpierrez, Guillermo E

    Journal of diabetes and its complications

    2023  Volume 37, Issue 12, Page(s) 108649

    MeSH term(s) Humans ; Hypoglycemic Agents ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/therapy ; Glucagon-Like Peptide-1 Receptor
    Chemical Substances Hypoglycemic Agents ; Glucagon-Like Peptide-1 Receptor
    Language English
    Publishing date 2023-11-19
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1105840-7
    ISSN 1873-460X ; 1056-8727
    ISSN (online) 1873-460X
    ISSN 1056-8727
    DOI 10.1016/j.jdiacomp.2023.108649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Web Exclusive. Annals for Hospitalists Inpatient Notes - How We Treat Hyperglycemia in the Hospital.

    Pasquel, Francisco J / Umpierrez, Guillermo E

    Annals of internal medicine

    2022  Volume 174, Issue 8, Page(s) HO2–HO4

    Language English
    Publishing date 2022-07-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/M21-2789
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  6. Article ; Online: Diabetic ketoacidosis risk during the COVID-19 pandemic.

    Vellanki, Priyathama / Umpierrez, Guillermo E

    The lancet. Diabetes & endocrinology

    2021  Volume 9, Issue 10, Page(s) 643–644

    MeSH term(s) COVID-19 ; Diabetes Mellitus, Type 1/epidemiology ; Diabetic Ketoacidosis/epidemiology ; Humans ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2021-09-02
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ISSN 2213-8595
    ISSN (online) 2213-8595
    DOI 10.1016/S2213-8587(21)00241-2
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  7. Article ; Online: Estimation of glucose absorption, insulin sensitivity, and glucose effectiveness from the oral glucose tolerance test.

    Stefanovski, Darko / Smiley, Dawn D / Punjabi, Naresh M / Umpierrez, Guillermo E / Vellanki, Priyathama

    The Journal of clinical endocrinology and metabolism

    2024  

    Abstract: Context: Glucose tolerance during an oral glucose tolerance test (OGTT) is affected by variations in glucose effectiveness (GE) and glucose absorption and thus affects minimal model calculations of insulin sensitivity (SI). The widely used OGTT SI by ... ...

    Abstract Context: Glucose tolerance during an oral glucose tolerance test (OGTT) is affected by variations in glucose effectiveness (GE) and glucose absorption and thus affects minimal model calculations of insulin sensitivity (SI). The widely used OGTT SI by Dalla Man et al. does not account for variances in GE and glucose absorption.
    Objective: To develop a novel model that concurrently assesses SI, GE, and glucose absorption.
    Design: Cross-sectional.
    Setting: Academic Medical Center.
    Participants: Eighteen subjects without abnormalities on OGTT (controls) and 88 subjects with diabetes.
    Intervention: All subjects underwent 75-gram 120-minute 6-timepoint OGTT.
    Main outcomes: SI from the Dalla Man model was validated with the novel model Si using Bland Altman limits of agreement methodology. Comparisons of SI, GE, and gastrointestinal glucose half-life (GIGt1/2); a surrogate measure for glucose absorption were made between subjects with diabetes and controls.
    Results: In controls and diabetes, the novel model SI was higher than the current OGTT model. SI from both controls (ƿ=0.90, p < 0.001) and diabetes (ƿ=0.77, p < 0.001) has high agreement between models. GE was higher in diabetes (median:0.021 1/min, IQR [interquartile range]: 0.020-0.022) compared to controls (median:0.016 1/min, IQR: 0.015-0.017), p = 0.02. GIGt1/2 was shorter in diabetes (median: 48.404 min, IQR: 54.424-39.426) than in controls (median: 55.086 min, IQR: 61.368-48.502) without statistical difference.
    Conclusions: Our novel model SI has a good correlation with SI from the widely used Dalla Man's model while concurrently calculating GE and GIGt1/2. Thus, besides estimating SI, our novel model can quantify differences in insulin-independent glucose disposal mechanisms important for diabetes pathophysiology.
    Language English
    Publishing date 2024-05-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/clinem/dgae308
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  8. Article ; Online: Diabetes and Atherosclerotic Cardiovascular Disease: Novel Insights and Therapeutic Strategies.

    Umpierrez, Guillermo E

    Endocrinology and metabolism clinics of North America

    2017  Volume 47, Issue 1, Page(s) xv–xvi

    MeSH term(s) Atherosclerosis/therapy ; Cardiovascular Diseases/therapy ; Diabetes Mellitus/therapy ; Humans
    Language English
    Publishing date 2017-12-16
    Publishing country United States
    Document type Editorial
    ZDB-ID 92116-6
    ISSN 1558-4410 ; 0889-8529
    ISSN (online) 1558-4410
    ISSN 0889-8529
    DOI 10.1016/j.ecl.2017.12.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Diabetes: SGLT2 inhibitors and diabetic ketoacidosis - a growing concern.

    Umpierrez, Guillermo E

    Nature reviews. Endocrinology

    2017  Volume 13, Issue 8, Page(s) 441–442

    MeSH term(s) Diabetes Mellitus, Type 2 ; Diabetic Ketoacidosis ; Humans ; Hypoglycemic Agents ; Sodium-Glucose Transporter 2
    Chemical Substances Hypoglycemic Agents ; Sodium-Glucose Transporter 2
    Language English
    Publishing date 2017-06-16
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 2489381-X
    ISSN 1759-5037 ; 1759-5029
    ISSN (online) 1759-5037
    ISSN 1759-5029
    DOI 10.1038/nrendo.2017.77
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  10. Article ; Online: Intervention with Therapeutic Agents, Understanding the Path to Remission to Type 2 Diabetes: Part 2.

    Hao, Shuai / Umpierrez, Guillermo E / Vellanki, Priyathama

    Endocrinology and metabolism clinics of North America

    2022  Volume 52, Issue 1, Page(s) 39–47

    Abstract: Type 2 diabetes is characterized by progressive decline in pancreatic β-cell function. Newer agents, such as glucagon-like peptide-1 receptor agonist (GLP-1RA) and dual incretin agonists, can augment β-cell function and delay the need for additional ... ...

    Abstract Type 2 diabetes is characterized by progressive decline in pancreatic β-cell function. Newer agents, such as glucagon-like peptide-1 receptor agonist (GLP-1RA) and dual incretin agonists, can augment β-cell function and delay the need for additional antihyperglycemics. However, the effect on β-cell function ceases after stopping the medications. When combined with intensive lifestyle modifications, higher doses of GLP-1RA than those used for diabetes treatment can be used to induce weight loss. More research is needed on whether the weight loss achieved with GLP1-RA can be sustained after stopping medication and in turn can sustain diabetes remission.
    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/drug therapy ; Glucagon-Like Peptide-1 Receptor/agonists ; Glucagon-Like Peptide-1 Receptor/therapeutic use ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/therapeutic use ; Weight Loss
    Chemical Substances Glucagon-Like Peptide-1 Receptor ; Hypoglycemic Agents
    Language English
    Publishing date 2022-11-18
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 92116-6
    ISSN 1558-4410 ; 0889-8529
    ISSN (online) 1558-4410
    ISSN 0889-8529
    DOI 10.1016/j.ecl.2022.07.004
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