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  1. Article: Brain vessel anomalies in autosomal dominant polycystic kidney disease.

    Ejma, Maria / Urbanowski, Pawel / Brodowski, Miroslaw / Guranski, Konstanty / Hendrich, Barbara / Krajewska, Magdalena

    The National medical journal of India

    2020  Volume 32, Issue 3, Page(s) 189

    MeSH term(s) Adult ; Cerebral Veins/abnormalities ; Cerebral Veins/diagnostic imaging ; Child, Preschool ; Female ; Humans ; Intracranial Aneurysm ; Moyamoya Disease ; Polycystic Kidney, Autosomal Dominant ; Vascular Malformations
    Language English
    Publishing date 2020-03-04
    Publishing country India
    Document type Case Reports ; Journal Article
    ZDB-ID 645116-0
    ISSN 0970-258X
    ISSN 0970-258X
    DOI 10.4103/0970-258X.278698
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Safety and Outcome of Revascularization Treatment in Patients With Acute Ischemic Stroke and COVID-19: The Global COVID-19 Stroke Registry.

    Marto, João Pedro / Strambo, Davide / Ntaios, George / Nguyen, Thanh N / Herzig, Roman / Czlonkowska, Anna / Demeestere, Jelle / Mansour, Ossama Yassin / Salerno, Alexander / Wegener, Susanne / Baumgartner, Philipp / Cereda, Carlo W / Bianco, Giovanni / Beyeler, Morin / Arnold, Marcel / Carrera, Emmanuel / Machi, Paolo / Altersberger, Valerian / Bonati, Leo /
    Gensicke, Henrik / Bolognese, Manuel / Peters, Nils / Wetzel, Stephan / Magriço, Marta / Ramos, João Nuno / Sargento-Freitas, João / Machado, Rita / Maia, Carolina / Machado, Egídio / Nunes, Ana Paiva / Ferreira, Patricia / Pinho E Melo, Teresa / Dias, Mariana Carvalho / Paula, André / Correia, Manuel Alberto / Castro, Pedro / Azevedo, Elsa / Albuquerque, Luís / Alves, José Nuno / Ferreira-Pinto, Joana / Meira, Torcato / Pereira, Liliana / Rodrigues, Miguel / Araujo, Andre Pinho / Rodrigues, Marta / Rocha, Mariana / Pereira-Fonseca, Ângelo / Ribeiro, Luís / Varela, Ricardo / Malheiro, Sofia / Cappellari, Manuel / Zivelonghi, Cecilia / Sajeva, Giulia / Zini, Andrea / Gentile, Mauro / Forlivesi, Stefano / Migliaccio, Ludovica / Sessa, Maria / La Gioia, Sara / Pezzini, Alessandro / Sangalli, Davide / Zedde, Marialuisa / Pascarella, Rosario / Ferrarese, Carlo / Beretta, Simone / Diamanti, Susanna / Schwarz, Ghil / Frisullo, Giovanni / Marcheselli, Simona / Seners, Pierre / Sabben, Candice / Escalard, Simon / Piotin, Michel / Maïer, Benjamin / Charbonnier, Guillaume / Vuillier, Fabrice / Legris, Loïc / Cuisenier, Pauline / Vodret, Francesca R / Marnat, Gaultier / Liegey, Jean-Sebastien / Sibon, Igor / Flottmann, Fabian / Broocks, Gabriel / Gloyer, Nils-Ole / Bohmann, Ferdinand O / Schaefer, Jan Hendrik / Nolte, Christian / Audebert, Heinrich J / Siebert, Eberhard / Sykora, Marek / Lang, Wilfried / Ferrari, Julia / Mayer-Suess, Lukas / Knoflach, Michael / Gizewski, Elke Ruth / Stolp, Jeffrey / Stolze, Lotte J / Coutinho, Jonathan M / Nederkoorn, Paul / van den Wijngaard, Ido / De Meris, Joke / Lemmens, Robin / De Raedt, Sylvie / Vandervorst, Fenne / Rutgers, Matthieu Pierre / Guilmot, Antoine / Dusart, Anne / Bellante, Flavio / Calleja-Castaño, Patricia / Ostos, Fernando / González-Ortega, Guillermo / Martín-Jiménez, Paloma / García-Madrona, Sebastian / Cruz-Culebras, Antonio / Vera, Rocio / Matute, Maria Consuelo / Fuentes, Blanca / Alonso-de-Leciñana, María / Rigual, Ricardo / Díez-Tejedor, Exuperio / Perez-Sanchez, Soledad / Montaner, Joan / Díaz-Otero, Fernando / Pérez-de-la-Ossa, Natalia / Flores-Pina, Belén / Muñoz-Narbona, Lucia / Chamorro, Angel / Rodríguez-Vázquez, Alejandro / Renú, Arturo / Ayo-Martin, Oscar / Hernández-Fernández, Francisco / Segura, Tomas / Tejada-Meza, Herbert / Sagarra-Mur, Daniel / Serrano-Ponz, Marta / Hlaing, Thant / See, Isaiah / Simister, Robert / Werring, David / Kristoffersen, Espen Saxhaug / Nordanstig, Annika / Jood, Katarina / Rentzos, Alexandros / Šimůnek, Libor / Krajíčková, Dagmar / Krajina, Antonín / Mikulik, Robert / Cviková, Martina / Vinklárek, Jan / Školoudík, David / Roubec, Martin / Hurtikova, Eva / Hrubý, Rostislav / Ostry, Svatopluk / Skoda, Ondrej / Pernicka, Marek / Jurak, Lubomir / Eichlová, Zuzana / Jíra, Martin / Kovar, Martin / Panský, Michal / Mencl, Pavel / Palouskova, Hana / Tomek, Aleš / Janský, Petr / Olšerová, Anna / Sramek, Martin / Havlicek, Roman / Malý, Petr / Trakal, Lukáš / Fiksa, Jan / Slovák, Matěj / Karlinski, Michal Adam / Nowak, Maciej / Sienkiewicz-Jarosz, Halina / Bochynska, Anna / Wrona, Pawel / Homa, Tomasz / Sawczynska, Katarzyna / Slowik, Agnieszka / Wlodarczyk, Ewa / Wiacek, Marcin / Tomaszewska-Lampart, Izabella / Sieczkowski, Bartosz / Bartosik-Psujek, Halina / Bilik, Marta / Bandzarewicz, Anna / Dorobek, Malgorzata / Zielinska-Turek, Justyna / Nowakowska-Kotas, Marta / Obara, Krystian / Urbanowski, Paweł / Budrewicz, Slawomir / Guziński, Maciej / Świtońska, Milena / Rutkowska, Iwona / Sobieszak-Skura, Paulina / Labuz-Roszak, Beata M / Debiec, Aleksander / Staszewski, Jacek / Stępień, Adam / Zwiernik, Jacek / Wasilewski, Grzegorz / Tiu, Cristina / Terecoasă, Elena Oana / Radu, Razvan Alexandru / Negrila, Anca / Dorobat, Bogdan / Panea, Cristina / Tiu, Vlad / Petrescu, Simona / Ozdemir, Atilla / Mahmoud, Mostafa / El-Samahy, Hussam / Abdelkhalek, Hazem / Al-Hashel, Jasem / Ismail, Ismail Ibrahim / Salmeen, Athari / Ghoreishi, Abdoreza / Sabetay, Sergiu Ionut / Gross, Hana / Klein, Piers / Abdalkader, Mohamad / Jabbour, Pascal / El Naamani, Kareem / Tjoumakaris, Stavropoula / Abbas, Rawad / Mohamed, Ghada A / Chebl, Alex / Min, Jiangyong / Hovingh, Majesta / Tsai, Jenney P / Khan, Muhib / Nalleballe, Krishna / Onteddu, Sanjeeva / Masoud, Hesham / Michael, Mina / Kaur, Navreet / Maali, Laith / Abraham, Michael G / Khandelwal, Priyank / Bach, Ivo / Ong, Melody / Babici, Denis / Khawaja, Ayaz M / Hakemi, Maryam / Rajamani, Kumar / Cano-Nigenda, Vanessa / Arauz, Antonio / Amaya, Pablo / Llanos, Natalia / Arango, Akemi / Vences, Miguel Ángel / Barrientos Guerra, Jose Dominguo / Caetano, Rayllene / Martins, Rodrigo Targa / Scollo, Sergio Daniel / Yalung, Patrick Matic / Nagendra, Shashank / Gaikwad, Abhijit / Seo, Kwon-Duk / Georgiopoulos, Georgios / Nogueira, Raul G / Michel, Patrik

    Neurology

    2022  Volume 100, Issue 7, Page(s) e739–e750

    Abstract: Background and objectives: COVID-19-related inflammation, endothelial dysfunction, and coagulopathy may increase the bleeding risk and lower the efficacy of revascularization treatments in patients with acute ischemic stroke (AIS). We aimed to evaluate ... ...

    Abstract Background and objectives: COVID-19-related inflammation, endothelial dysfunction, and coagulopathy may increase the bleeding risk and lower the efficacy of revascularization treatments in patients with acute ischemic stroke (AIS). We aimed to evaluate the safety and outcomes of revascularization treatments in patients with AIS and COVID-19.
    Methods: This was a retrospective multicenter cohort study of consecutive patients with AIS receiving intravenous thrombolysis (IVT) and/or endovascular treatment (EVT) between March 2020 and June 2021 tested for severe acute respiratory syndrome coronavirus 2 infection. With a doubly robust model combining propensity score weighting and multivariate regression, we studied the association of COVID-19 with intracranial bleeding complications and clinical outcomes. Subgroup analyses were performed according to treatment groups (IVT-only and EVT).
    Results: Of a total of 15,128 included patients from 105 centers, 853 (5.6%) were diagnosed with COVID-19; of those, 5,848 (38.7%) patients received IVT-only and 9,280 (61.3%) EVT (with or without IVT). Patients with COVID-19 had a higher rate of symptomatic intracerebral hemorrhage (SICH) (adjusted OR 1.53; 95% CI 1.16-2.01), symptomatic subarachnoid hemorrhage (SSAH) (OR 1.80; 95% CI 1.20-2.69), SICH and/or SSAH combined (OR 1.56; 95% CI 1.23-1.99), 24-hour mortality (OR 2.47; 95% CI 1.58-3.86), and 3-month mortality (OR 1.88; 95% CI 1.52-2.33). Patients with COVID-19 also had an unfavorable shift in the distribution of the modified Rankin score at 3 months (OR 1.42; 95% CI 1.26-1.60).
    Discussion: Patients with AIS and COVID-19 showed higher rates of intracranial bleeding complications and worse clinical outcomes after revascularization treatments than contemporaneous non-COVID-19 patients receiving treatment. Current available data do not allow direct conclusions to be drawn on the effectiveness of revascularization treatments in patients with COVID-19 or to establish different treatment recommendations in this subgroup of patients with ischemic stroke. Our findings can be taken into consideration for treatment decisions, patient monitoring, and establishing prognosis.
    Trial registration information: The study was registered under ClinicalTrials.gov identifier NCT04895462.
    MeSH term(s) Humans ; Ischemic Stroke/epidemiology ; Ischemic Stroke/surgery ; Fibrinolytic Agents/therapeutic use ; Brain Ischemia/complications ; Brain Ischemia/epidemiology ; Brain Ischemia/surgery ; Cohort Studies ; Thrombolytic Therapy/adverse effects ; Treatment Outcome ; COVID-19/complications ; Stroke/epidemiology ; Stroke/therapy ; Stroke/diagnosis ; Intracranial Hemorrhages/etiology ; Cerebral Hemorrhage/complications ; Endovascular Procedures/adverse effects ; Registries
    Chemical Substances Fibrinolytic Agents
    Language English
    Publishing date 2022-11-09
    Publishing country United States
    Document type Multicenter Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000201537
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui II Zs.153: Show issues Location:
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