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  1. Article ; Online: Case for diagnosis. Unilateral nodule on the nipple: erosive adenomatosis of the nipple.

    Mendez-Flores, Raúl Gerardo / Uriarte-Ruiz, Karen / Vega-Memije, María Elisa / Ruiz-Gomez, Daniela / Toussaint-Caire, Sonia

    Anais brasileiros de dermatologia

    2023  Volume 98, Issue 6, Page(s) 847–849

    Language English
    Publishing date 2023-07-08
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 433655-0
    ISSN 1806-4841 ; 0365-0596
    ISSN (online) 1806-4841
    ISSN 0365-0596
    DOI 10.1016/j.abd.2022.09.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Differential expression of TOB/BTG family members in patients with plaque psoriasis: cross-sectional study.

    Barrera-Ochoa, Carlos A / Fonseca-Camarillo, Gabriela / Vega-Memije, María Elisa / Furuzawa-Carballeda, Janette / Uriarte-Ruiz, Karen / Fernández-Camargo, Dheni Aidé / Yamamoto-Furusho, Jesús K

    Immunologic research

    2023  Volume 72, Issue 2, Page(s) 234–241

    Abstract: TOB/BTG is a family of antiproliferative proteins that play an important role in the regulation of immune responses, acting as lymphocyte activators and macrophage-mediated cytotoxicity. No previous studies have explored their role in patients with ... ...

    Abstract TOB/BTG is a family of antiproliferative proteins that play an important role in the regulation of immune responses, acting as lymphocyte activators and macrophage-mediated cytotoxicity. No previous studies have explored their role in patients with psoriasis. The aim of this study was to characterize the expression of TOB/BTG family and their co-localization in skin from patients with psoriasis. This is an exploratory, observational, and cross-sectional study that included 24 plaque psoriasis patients and 15 controls. Gene expression of TOB/BTG family was determinate by RT-PCR. Protein products of TOB/BTG were evaluated by immunohistochemistry and compared with control skin tissues. Holm-Sidak's multiple comparisons test was performed. TOB/BTG family mRNA levels and protein expression were significantly decreased in psoriatic skin tissue compared to non-inflammatory control skin tissue. Double-positive cell TOB1/2, BTG1,2 and BTG4/CD16 expressions were found in normal control skin tissues through epidermis and dermis (p < 0.001) and lesser percentage in patients with mild, almost absent in moderate-severe plaque psoriasis. This is the first report of the TOB/BTG family gene and protein expression in skin tissues by a CD16 + subpopulation in plaque psoriasis. TOB/BTG family protein might represent a new therapeutic target among immune-mediated inflammatory diseases.
    MeSH term(s) Humans ; Tumor Suppressor Proteins/genetics ; Cross-Sectional Studies ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Protein Processing, Post-Translational ; Psoriasis/genetics
    Chemical Substances Tumor Suppressor Proteins ; Cell Cycle Proteins
    Language English
    Publishing date 2023-10-24
    Publishing country United States
    Document type Observational Study ; Journal Article
    ZDB-ID 632857-x
    ISSN 1559-0755 ; 0257-277X
    ISSN (online) 1559-0755
    ISSN 0257-277X
    DOI 10.1007/s12026-023-09427-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Comparison between endoloop and linear mechanical stapler for the appendicular stump closure.

    Granados-Romero, Juan J / Valderrama-Treviño, Alan I / Barrera-Mera, Baltazar / Uriarte-Ruíz, Karen / Banegas-Ruiz, Rodrigo / Ceballos-Villalva, Jesús C

    Cirugia y cirujanos

    2018  Volume 86, Issue 5, Page(s) 428–431

    Abstract: Introducción: En las últimas décadas es creciente el abordaje por mínima invasión de patologías abdominales debido a sus beneficios evidentes. El cuadro apendicular es la principal emergencia quirúrgica, con diferentes métodos del cierre de la base ... ...

    Title translation Comparación entre ligadura con lazo hemostático y engrapadora mecánica lineal para el cierre de base apendicular.
    Abstract Introducción: En las últimas décadas es creciente el abordaje por mínima invasión de patologías abdominales debido a sus beneficios evidentes. El cuadro apendicular es la principal emergencia quirúrgica, con diferentes métodos del cierre de la base apendicular. En este artículo comparamos dicho cierre con engrapadora lineal o ligadura con lazo hemostático, para analizar la frecuencia de complicaciones como absceso, dehiscencia y seroma.
    Método: Se realizó un estudio prospectivo, observacional y descriptivo, con un total de 703 procedimientos, empleando en 567 pacientes ligadura con lazo hemostático y en 136 engrapadora lineal, operados por los mismos cirujano y equipo quirúrgico, con curva de aprendizaje concluida.
    Resultados: Las complicaciones referidas en el presente estudio son absceso (n = 5), dehiscencia (n = 3) y seroma (n = 3). De acuerdo con las fases de la patología apendicular: fase 1 o apéndice congestivo, no presentaron complicaciones; fase 2 o supurativo, se reportó un caso de dehiscencia de herida quirúrgica con el uso de ligadura con lazo hemostático; fase 3 o necrótico, se reportó un caso de seroma en un paciente tratado con ligadura con lazo hemostático; y fase 4 o perforado, se encuentra diferencia significativa en el caso de abscesos, reportando cinco con el uso de ligadura con lazo hemostático y ninguno con engrapadora lineal.
    Conclusiones: En nuestro estudio no existe diferencia estadísticamente significativa entre el uso de engrapadora lineal o ligadura con lazo hemostático en las fases apendiculares 1-3; en la fase 4 es de utilidad significativa el uso de engrapadora lineal ante la incidencia de abscesos.
    Introduction: In the last decades, the approach by minimally invasive surgery of abdominal pathologies is growing due to its evident benefits; the appendicular cases being the main surgical emergency, with different methods of closing the appendicular base. In this article, we compared the appendicular base closure with linear stapler and endoloop, to analyze the frequency of complications such as abscess, dehiscence and seroma.
    Method: A prospective, observational and descriptive study was conducted, with a total of 703 procedures, using 567 endoloop patients and 136 linear stapler, operated by the same surgeon and surgical team, with a completed learning curve.
    Results: The complications referred in the present study were patients with abscess (n = 5), dehiscence (n = 3) and seroma (n = 3). According to the phases of the appendiceal pathology: phase 1 or congestive appendix did not present complications; phase 2 or suppurative was reported one case of surgical wound dehiscence in the use of endoloop; in phase 3 or necrotic, one case of seroma was reported in a patient treated with endoloop; while in phase 4 or perforated there is a significant difference in the case of abscesses, reporting five in the use of endoloop and none in the case of a linear stapler.
    Conclusions: In our study there is no statistically significant difference between the use of linear stapler or endoloop in the early appendicular phases; being of significant utility in Phase 4 the use of linear stapler for the incidence of abscesses.
    MeSH term(s) Abdominal Abscess/epidemiology ; Abdominal Abscess/etiology ; Abdominal Wound Closure Techniques/economics ; Abdominal Wound Closure Techniques/instrumentation ; Appendectomy/economics ; Appendectomy/methods ; Hospitals, Private ; Humans ; Laparoscopy/economics ; Laparoscopy/methods ; Ligation/economics ; Ligation/instrumentation ; Ligation/methods ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Prospective Studies ; Seroma/epidemiology ; Seroma/etiology ; Surgical Stapling/economics ; Surgical Stapling/instrumentation ; Surgical Stapling/methods ; Surgical Wound Dehiscence/epidemiology ; Surgical Wound Dehiscence/etiology ; Surgical Wound Infection/epidemiology ; Surgical Wound Infection/etiology
    Language Spanish
    Publishing date 2018-09-17
    Publishing country Mexico
    Document type Comparative Study ; Journal Article ; Observational Study
    ZDB-ID 730699-4
    ISSN 2444-054X ; 0009-7411
    ISSN (online) 2444-054X
    ISSN 0009-7411
    DOI 10.24875/CIRU.18000258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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