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  1. Article: Speech therapy and hyperbaric oxygen for aphasia after carbon monoxide intoxication.

    Ruiz-Mambrilla, Marta / Dueñas-Ruiz, Antonio / Pérez-Castrillón, José L / Usategui-Martín, Iciar / Dueñas-Laita, Antonio

    Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc

    2023  Volume 50, Issue 1, Page(s) 3–7

    Abstract: Acute carbon monoxide (CO) intoxication may result in delayed neurological sequelae, which can include amnesia, ataxia, aphasia, emotional lability, disorientation, dysphagia, and other manifestations. A 27-year-old man reported symptoms of aphasia with ... ...

    Abstract Acute carbon monoxide (CO) intoxication may result in delayed neurological sequelae, which can include amnesia, ataxia, aphasia, emotional lability, disorientation, dysphagia, and other manifestations. A 27-year-old man reported symptoms of aphasia with agraphia and alexia in a review after CO intoxication. The patient received outpatient speech therapy, as well as repeated sessions of hyperbaric oxygen for 15 days, interspersing speech therapy with hyperbaric oxygen therapy for two months. After this period of combined treatment the aphasic symptomatology remitted, and oral and written language was normal. The complete disappearance of aphasia with agraphia and alexia confirms the efficacy of the combined intervention. More data from large clinical studies are needed to assess the outcomes of hyperbaric oxygen treatment in patients with delayed neurological sequelae after CO intoxication, but this case suggests it may be a good therapeutic option in combination with specific speech therapy.
    MeSH term(s) Male ; Humans ; Adult ; Hyperbaric Oxygenation ; Carbon Monoxide ; Agraphia/complications ; Agraphia/therapy ; Speech Therapy ; Aphasia/complications ; Aphasia/therapy ; Carbon Monoxide Poisoning/complications ; Dyslexia/complications ; Dyslexia/therapy
    Chemical Substances Carbon Monoxide (7U1EE4V452)
    Language English
    Publishing date 2023-02-17
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1154414-4
    ISSN 1066-2936
    ISSN 1066-2936
    DOI 10.22462/01.01.2023.15
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1069: Show issues Location:
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  2. Article ; Online: Healthcare facility associated Clostridium difficile infection.

    Sánchez-Muñoz, Luis Angel / Usategui-Martín, Iciar / Silvagni-Gutiérrez, Hana

    Medicina clinica

    2019  Volume 153, Issue 11, Page(s) e61

    Title translation Infección por Clostridium difficile asociada a la asistencia sanitaria.
    MeSH term(s) Clostridium Infections ; Clostridium difficile ; Cross Infection ; Enterocolitis, Pseudomembranous ; Home Care Services, Hospital-Based ; Humans
    Language Spanish
    Publishing date 2019-04-24
    Publishing country Spain
    Document type Letter ; Comment
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2019.01.036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Shared care in polypathological patients: about intravenous iron.

    Usategui-Martín, Iciar / Martín-Merino, Mateo / Sánchez-Muñoz, Luis Angel

    Medicina clinica

    2019  Volume 153, Issue 9, Page(s) e49

    Title translation Atención compartida en pacientes pluripatológicos: a propósito del hierro intravenoso.
    MeSH term(s) Ambulatory Care ; Humans ; Iron ; Outpatients ; Primary Health Care
    Chemical Substances Iron (E1UOL152H7)
    Language Spanish
    Publishing date 2019-05-18
    Publishing country Spain
    Document type Letter ; Comment
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2019.01.040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Dementia and feeding problems: PEG feeding tube or not?

    Sánchez-Muñoz, Luis Angel / Silvagni-Gutiérrez, Hana / Usategui-Martín, Iciar

    Medicina clinica

    2019  Volume 153, Issue 11, Page(s) e59–e60

    Title translation Demencia y problemas de alimentación: ¿sonda PEG o no?
    MeSH term(s) Dementia/complications ; Enteral Nutrition/instrumentation ; Enteral Nutrition/methods ; Feeding and Eating Disorders/etiology ; Feeding and Eating Disorders/therapy ; Gastrostomy ; Humans ; Intubation, Gastrointestinal ; Practice Guidelines as Topic
    Language Spanish
    Publishing date 2019-05-20
    Publishing country Spain
    Document type Letter
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2019.01.041
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  5. Article ; Online: Cardiogenic shock and lower limb ischemia as complications of Kawasaki disease.

    Usategui-Martín, Iciar / Calero-Paniagua, Ismael / Barbado-Ajo, M Julia

    Medicina clinica

    2017  Volume 149, Issue 12, Page(s) 558–559

    Title translation Shock cardiogénico e isquemia aguda de miembros inferiores como complicaciones de la enfermedad de Kawasaki.
    MeSH term(s) Adolescent ; Fatal Outcome ; Humans ; Ischemia/etiology ; Lower Extremity/blood supply ; Male ; Mucocutaneous Lymph Node Syndrome/complications ; Mucocutaneous Lymph Node Syndrome/diagnosis ; Shock, Cardiogenic/etiology
    Language Spanish
    Publishing date 2017-07-31
    Publishing country Spain
    Document type Case Reports ; Letter
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2017.06.043
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  6. Article ; Online: The nutritional status of the elderly patient infected with COVID-19: the forgotten risk factor?

    Abadía Otero, Jessica / Briongos Figuero, Laisa Socorro / Gabella Mattín, Miriam / Usategui Martín, Iciar / Cubero Morais, Pablo / Cuellar Olmedo, Luis / Inglada Galiana, Luis / Dueñas Gutiérrez, Carlos / Carretero Gómez, Juana / Corral Gudino, Luis / Miramontes González, José Pablo

    Current medical research and opinion

    2021  Volume 37, Issue 4, Page(s) 549–554

    Abstract: Background: Since the first cases of COVID-19 were reported in Wuhan, the nutritional status of individuals infected with the virus has not been included in the risk profiles prepared. However, nutritional status, along with other factors, is decisive ... ...

    Abstract Background: Since the first cases of COVID-19 were reported in Wuhan, the nutritional status of individuals infected with the virus has not been included in the risk profiles prepared. However, nutritional status, along with other factors, is decisive in the evolution of patients with other infectious diseases. The nutritional status of individuals is considered an indicator of health status. Furthermore, optimal nutritional status transcends the individual, and poor diet in a population can be considered a group risk factor. Evidence exists on the influence that diet has on the immune system and susceptibility to disease.
    Objective: To evaluate the nutritional status of patients older than 65 years who were admitted due to COVID-19 and how this has influenced the evolution of patients.
    Design: This prospective and observational study was performed in patients with COVID-19 infection confirmed by real-time polymerase chain reaction. Data were collected from the first 24 h of admission. All patients admitted during one month to the wards assigned to COVID-19 infection were included.
    Results: A total of 83 patients were studied. The statistical study of mortality showed associations with age (
    Conclusions: Malnutrition was a risk factor as powerful as others such as hypertension, age, and different comorbidities. We must evaluate and treat the nutritional status of elderly patients with COVID-19 infection since it directly affects their evolution.
    MeSH term(s) Aged ; Aged, 80 and over ; COVID-19/etiology ; COVID-19/metabolism ; COVID-19/mortality ; Female ; Humans ; Male ; Malnutrition/complications ; Nutritional Status ; Prospective Studies ; Risk Factors ; SARS-CoV-2
    Language English
    Publishing date 2021-02-16
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 80296-7
    ISSN 1473-4877 ; 0300-7995
    ISSN (online) 1473-4877
    ISSN 0300-7995
    DOI 10.1080/03007995.2021.1882414
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 955: Show issues Location:
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  7. Article ; Online: Effect of intravenous pulses of methylprednisolone 250 mg versus dexamethasone 6 mg in hospitalised adults with severe COVID-19 pneumonia: An open-label randomised trial.

    Corral-Gudino, Luis / Cusacovich, Ivan / Martín-González, Jose Ignacio / Muela-Molinero, Alberto / Abadía-Otero, Jésica / González-Fuentes, Roberto / Ruíz-de-Temiño, Ángela / Tapia-Moral, Elena / Cuadrado-Medina, Francisca / Martín-Asenjo, Miguel / Miramontes-González, Pablo / Delgado-González, Jose Luis / Ines, Sandra / Abad-Manteca, Laura / Usategui-Martín, Iciar / Ruiz-Albi, Tomás / Miranda-Riaño, Sara / Rodríguez-Fortúnez, Patricia / Rodríguez-Jiménez, Consuelo /
    López-Franco, Esperanza / Marcos, Miguel

    European journal of clinical investigation

    2022  , Page(s) e13881

    Abstract: Background: The efficacy and safety of high versus medium doses of glucocorticoids for the treatment of patients with COVID-19 has shown mixed outcomes in controlled trials and observational studies. We aimed to evaluate the effectiveness of ... ...

    Abstract Background: The efficacy and safety of high versus medium doses of glucocorticoids for the treatment of patients with COVID-19 has shown mixed outcomes in controlled trials and observational studies. We aimed to evaluate the effectiveness of methylprednisolone 250 mg bolus versus dexamethasone 6 mg in patients with severe COVID-19.
    Methods: A randomised, open-label, controlled trial was conducted between February and August 2021 at four hospitals in Spain. The trial was suspended after the first interim analysis since the investigators considered that continuing the trial would be futile. Patients were randomly assigned in a 1:1 ratio to receive dexamethasone 6 mg once daily for up to 10 days or methylprednisolone 250 mg once daily for 3 days.
    Results: Of the 128 randomised patients, 125 were analysed (mean age 60 ± 17 years; 82 males [66%]). Mortality at 28 days was 4.8% in the 250 mg methylprednisolone group versus 4.8% in the 6 mg dexamethasone group (absolute risk difference, 0.1% [95% CI, -8.8 to 9.1%]; p = 0.98). None of the secondary outcomes (admission to the intensive care unit, non-invasive respiratory or high-flow oxygen support, additional immunosuppressive drugs, or length of stay), or prespecified sensitivity analyses were statistically significant. Hyperglycaemia was more frequent in the methylprednisolone group at 27.0 versus 8.1% (absolute risk difference, -18.9% [95% CI, -31.8 to - 5.6%]; p = 0.007).
    Conclusions: Among severe but not critical patients with COVID-19, 250 mg/d for 3 days of methylprednisolone compared with 6 mg/d for 10 days of dexamethasone did not result in a decrease in mortality or intubation.
    Language English
    Publishing date 2022-09-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 186196-7
    ISSN 1365-2362 ; 0014-2972 ; 0960-135X
    ISSN (online) 1365-2362
    ISSN 0014-2972 ; 0960-135X
    DOI 10.1111/eci.13881
    Database MEDical Literature Analysis and Retrieval System OnLINE

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