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Article: Glaucoma Surgery and Ocular Blood Flow in Colour Doppler Imaging: Is There a Link?

Zarzecki, Mateusz / Obuchowska, Iwona / Ustymowicz, Andrzej / Konopińska, Joanna

Clinical ophthalmology (Auckland, N.Z.)

2024 Volume 18, Page(s) 49–60

Abstract: Glaucoma is a common cause of blindness worldwide. This disease is characterised by increased intraocular pressure (IOP) and the concomitant disruption of ocular haemodynamic. Several studies have demonstrated that trabeculectomy is associated with ... ...

Abstract	Glaucoma is a common cause of blindness worldwide. This disease is characterised by increased intraocular pressure (IOP) and the concomitant disruption of ocular haemodynamic. Several studies have demonstrated that trabeculectomy is associated with changes in extraocular blood flow. In this study, we reviewed the available evidence on the use of colour Doppler imaging to evaluate and manage patients with open-angle glaucoma. We present the detailed anatomy of ocular blood flow to provide a background for the research findings. We also discuss the physiological foundations of ocular blood flow and detailed flow characteristics of specific extraocular vessels. Finally, we reviewed published studies that analysed the effects of glaucoma surgery on the blood flow parameters of the eye.
Language	English
Publishing date	2024-01-06
Publishing country	New Zealand
Document type	Journal Article ; Review
ISSN	1177-5467
ISSN	1177-5467
DOI	10.2147/OPTH.S441805
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Article ; Online: Blood flow disturbances in the central retinal artery in patients with bilateral optic disc drusen.

Obuchowska, Iwona / Ustymowicz, Andrzej

Scientific reports

2020 Volume 10, Issue 1, Page(s) 11111

Abstract: To evaluate retrobulbar hemodynamics in patients with optic disc drusen (ODD) by color Doppler imaging. A prospective study included 52 patients with bilateral ODD and 50 age-matched controls. Blood flow in the central retinal artery (CRA) in both eyes ... ...

Abstract	To evaluate retrobulbar hemodynamics in patients with optic disc drusen (ODD) by color Doppler imaging. A prospective study included 52 patients with bilateral ODD and 50 age-matched controls. Blood flow in the central retinal artery (CRA) in both eyes was evaluated. Peak-systolic velocity (PSV), end-diastolic velocity (EDV), and the resistivity index (RI) were measured. Mean values of the blood flow Doppler parameters were compared between the patients with ODD and the controls. Both PSV and EDV in the CRA were significantly lower in patients with ODD than in the controls (p < 0.001). The RI in the CRA of ODD patients was significantly higher than in the controls (p < 0.001). Women with ODD presented with significantly lower values of PSV and EDV than men (p = 0.05 and p = 0.03, respectively). Arterial hypertension, cigarette smoking and location of ODD in the left or right eye did not exert a significant effect on the blood flow in the CRA. Blood flow in the CRA is considerably disturbed in patients with ODD. This disturbance might result from mechanical stenosis of the vascular wall caused by the drusen. Color Doppler ultrasound is a useful method in the assessment of retrobulbar hemodynamics in ODD.
MeSH term(s)	Adult ; Blood Flow Velocity ; Case-Control Studies ; Female ; Follow-Up Studies ; Hemodynamics ; Humans ; Male ; Middle Aged ; Optic Disk Drusen/blood ; Optic Disk Drusen/pathology ; Prognosis ; Prospective Studies ; Regional Blood Flow ; Retinal Artery/physiopathology ; Ultrasonography, Doppler, Color
Language	English
Publishing date	2020-07-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-020-68090-3
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Article: Ultrasonografia dopplerowska z obrazowaniem przepływu krwi w kolorze (USG-kolor Doppler) w diagnostyce okulistycznej--doświadczenia własne i przeglad literatury.

Ustymowicz, Andrzej

Klinika oczna

2008 Volume 110, Issue 1-3, Page(s) 108–111

Abstract: Color Doppler ultrasound examinations are effective and very useful to differentiate and diagnose ocular and orbital diseases. In the paper some aspects of these examinations are discussed: technique, examined vessels, blood flow parameters. Special ... ...

Title translation	Color Doppler ultrasound examinations of the eye and orbit--personal experience and literature review.
Abstract	Color Doppler ultrasound examinations are effective and very useful to differentiate and diagnose ocular and orbital diseases. In the paper some aspects of these examinations are discussed: technique, examined vessels, blood flow parameters. Special attention is paid to patient's safety, drawbacks and limitations of presented technique.
MeSH term(s)	Eye/blood supply ; Eye/diagnostic imaging ; Eye Diseases/diagnostic imaging ; Humans ; Orbit/blood supply ; Orbit/diagnostic imaging ; Orbital Diseases/diagnostic imaging ; Ultrasonography, Doppler, Color/methods
Language	Polish
Publishing date	2008
Publishing country	Poland
Document type	Journal Article ; Review
ZDB-ID	411755-4
ISSN	0023-2157
ISSN	0023-2157
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Article ; Online: Obesity-related parameters in carriers of some BDNF genetic variants may depend on daily dietary macronutrients intake.

Miksza, Urszula / Adamska-Patruno, Edyta / Bauer, Witold / Fiedorczuk, Joanna / Czajkowski, Przemyslaw / Moroz, Monika / Drygalski, Krzysztof / Ustymowicz, Andrzej / Tomkiewicz, Elwira / Gorska, Maria / Kretowski, Adam

Scientific reports

2023 Volume 13, Issue 1, Page(s) 6585

Abstract: Some common single-nucleotide polymorphisms of the brain-derived neurotrophic factor (BDNF) gene have been associated not only with the neurodegenerative diseases but also with some eating disorders. The aim of this study was to assess the possible ... ...

Abstract	Some common single-nucleotide polymorphisms of the brain-derived neurotrophic factor (BDNF) gene have been associated not only with the neurodegenerative diseases but also with some eating disorders. The aim of this study was to assess the possible differences in the obesity-related and glucose metabolism parameters between some BDNF genotypes', that may depend on the daily energy and macronutrients intake. In 484 adult participants we performed the anthropometric measurements, body composition analysis, and body fat distribution. The daily dietary intake was assessed using the 3-day food intake diaries. Blood glucose and insulin concentrations were measured at fasting and during oral glucose tolerance tests. Moreover, the visceral adipose tissue/subcutaneous adipose tissue (VAT/SAT) ratio and homeostatic model assessment of insulin resistance were calculated. We noted that participants carrying the GG genotype had lower skeletal muscle mass and fat free mass (FFM) when carbohydrate intake was > 48%, whereas they presented higher fat-free mass (FFM), and surprisingly higher total cholesterol and LDL-C concentrations when daily fiber intake was > 18 g. Moreover, in these subjects we noted higher waist circumference, BMI, and fasting glucose and insulin concentrations, when > 18% of total daily energy intake was delivered from proteins, and higher VAT content and HDL-C concentrations when > 30% of energy intake was derived from dietary fat. Our results suggest that glucose homeostasis and obesity-related parameters in carriers of some common variants of BDNF gene, especially in the GG (rs10835211) genotype carriers, may differ dependently on daily energy, dietary macronutrients and fiber intake.
MeSH term(s)	Adult ; Humans ; Brain-Derived Neurotrophic Factor/genetics ; Eating/genetics ; Glucose ; Insulin ; Nutrients/metabolism ; Obesity/genetics
Chemical Substances	Brain-Derived Neurotrophic Factor ; Glucose (IY9XDZ35W2) ; Insulin
Language	English
Publishing date	2023-04-21
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-33842-4
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Article: Diagnostyka obrazowa neuroboreliozy.

Ustymowicz, Andrzej

Neurologia i neurochirurgia polska

2003 Volume 37 Suppl 2, Page(s) 39–44

Abstract: Imaging techniques are commonly used in the diagnostics of the central nervous system disorders. Abnormalities found using MRI and MRS in neuroborreliosis patients are described. ...

Title translation	Neuroimaging in Lyme disease.
Abstract	Imaging techniques are commonly used in the diagnostics of the central nervous system disorders. Abnormalities found using MRI and MRS in neuroborreliosis patients are described.
MeSH term(s)	Brain/pathology ; Humans ; Lateral Ventricles/pathology ; Lyme Disease/diagnosis ; Magnetic Resonance Imaging
Language	Polish
Publishing date	2003
Publishing country	Poland
Document type	English Abstract ; Journal Article
ZDB-ID	415519-1
ISSN	1897-4260 ; 0028-3843
ISSN (online)	1897-4260
ISSN	0028-3843
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Article ; Online: Aplicación de la ecografía en la cateterización venosa central; lugares de acceso y técnicas del procedimiento.

Czyzewska, Dorota / Ustymowicz, Andrzej / Klukowski, Mark

Medicina clinica

2016 Volume 147, Issue 3, Page(s) 116–120

Abstract: Central venous catheterization is commonly performed in clinical practice. Traditional procedural technique is based on anatomical landmarks, but is associated with a high risk of failure and complications. To decrease their incidence European and ... ...

Title translation	Application of ultrasonography in central venous catheterization; access sites and procedure techniques.
Abstract	Central venous catheterization is commonly performed in clinical practice. Traditional procedural technique is based on anatomical landmarks, but is associated with a high risk of failure and complications. To decrease their incidence European and American societies recommend application of ultrasonography. Preliminary ultrasonographic examination allows for assessment of local anatomical relations as well as vessel morphology (diameter, patency), while real-time ultrasonography increases chances of successful needle insertion. This paper presents the most common venous access sites and procedure techniques.
Language	Spanish
Publishing date	2016-08-05
Publishing country	Spain
Document type	English Abstract ; Journal Article ; Review
ZDB-ID	411607-0
ISSN	1578-8989 ; 0025-7753
ISSN (online)	1578-8989
ISSN	0025-7753
DOI	10.1016/j.medcli.2016.02.032
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Article ; Online: Normal tolerance limits for side-to-side differences in diameters of major lower limbs arteries of 228 healthy subjects.

Kubarewicz, Krzysztof Jan / Ustymowicz, Andrzej / Czyzewska, Dorota / Kaminski, Marcin Jakub / Sledziewski, Rafal / Krejza, Jaroslaw

Advances in medical sciences

2019 Volume 65, Issue 1, Page(s) 30–38

Abstract: Purpose: To determine reference values and tolerance limits of between-side differences for the calibers of the common femoral artery (CFA), superficial femoral artery (SFA), popliteal artery (PA), dorsalis pedis artery (DPA), and posterior tibial ... ...

Abstract	Purpose: To determine reference values and tolerance limits of between-side differences for the calibers of the common femoral artery (CFA), superficial femoral artery (SFA), popliteal artery (PA), dorsalis pedis artery (DPA), and posterior tibial artery (PTA). Materials and methods: Calibers of arteries, defined as the largest distance between internal hyperechogenic lines of the intima-media complex of the arterial wall, were measured during the diastole phase determined from echo-tracking B mode ultrasound scanning and grey-scale ultrasound in 228 healthy volunteers aged 18-81 years (43.1 ± 16.7). Results: The mean, 95% confidence and tolerance limits covering 90% of population for left and right side of each artery were: CFA: 8.1 mm, 7.9-8.3 mm, 6.0-10.3 mm; 8.1 mm, 7.9-8.5 mm, 5.9-10.2 mm; SFA: 6.2 mm, 6.0-6.3 mm, 4.7-7.6 mm; 6.1 mm, 6.0-6.3 mm, 4.7-7.6 mm; PA: 6.1 mm, 6.0-6.2 mm, 4.6-7.6 mm; 6.1 mm, 5.9-6.2 mm, 4.5-7.6 mm; DPA: 2.0 mm, 1.9-2.0 mm, 1.2-2.7 mm; 2.0 mm, 1.9-2.0 mm, 1.2-2.8 mm; PTA: 2.1 mm, 2.0-2.1 mm, 1.4-2.8 mm; 2.1 mm, 2.1-2.2 mm, 1.4-2.8 mm, respectively. Tolerance limits for between-side differences and ratios were: CFA - 0.5-0.7 mm, 0.9-1.1; SFA - 0.5-0.6 mm, 0.9-1.1; PA - 0.5-0.5 mm, 0.9-1.1; DPA -0.4-0.4 mm, 0.8-1.2; PTA - 0.4-0.4 mm, 0.8-1.2. Regression analysis showed weight and age dependency of vessels diameters. There are no differences between men and woman in vessels size, except in DPA's, when body weight and age are taken into account in a regression analysis. Conclusions: We estimated normal reference tolerance limits of side-to-side differences in diameters of lower limb arteries. The limits can inform an investigator what differences in diameters occur in healthy individuals, and hence can serve as cut-offs in diagnostic and screening strategies.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Femoral Artery/anatomy & histology ; Femoral Artery/diagnostic imaging ; Healthy Volunteers ; Humans ; Lower Extremity/blood supply ; Male ; Middle Aged ; Popliteal Artery/anatomy & histology ; Popliteal Artery/diagnostic imaging ; Spinal Cord Dorsal Horn/anatomy & histology ; Spinal Cord Dorsal Horn/diagnostic imaging ; Tibial Arteries/anatomy & histology ; Tibial Arteries/diagnostic imaging ; Ultrasonography/methods ; Young Adult
Language	English
Publishing date	2019-12-24
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2273668-2
ISSN	1898-4002 ; 1896-1126
ISSN (online)	1898-4002
ISSN	1896-1126
DOI	10.1016/j.advms.2019.10.001
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Article ; Online: Cross-sectional area of the femoral vein varies with leg position and distance from the inguinal ligament.

Czyzewska, Dorota / Ustymowicz, Andrzej / Kowalewski, Radoslaw / Zurada, Anna / Krejza, Jaroslaw

PloS one

2017 Volume 12, Issue 8, Page(s) e0182623

Abstract: Purpose: The risk of complications associated with femoral venous catheterization could be potentially reduced if the procedure was performed at the location where the cross-sectional area (CSA) of the vessel is the largest. The diameter of the femoral ... ...

Abstract	Purpose: The risk of complications associated with femoral venous catheterization could be potentially reduced if the procedure was performed at the location where the cross-sectional area (CSA) of the vessel is the largest. The diameter of the femoral vein depends on leg position as well as the distance from the inguinal ligament. We determined the CSA of the right femoral vein in three different leg positions at two distances from the inguinal ligament. Subjects and methods: Informed consent was given by 205 healthy volunteers aged 19-39 years, mean: 23±3 years (108 women, 97 men). Ultrasonographic examinations were performed using a linear 14-MHz transducer with CSA measurements in three leg positions: abduction, abduction+external rotation, abduction+external rotation+90° knee flexion/frog-leg position; at levels 20 mm caudally to the inguinal ligament, and 20 mm caudally to the inguinal crease. Results: We found significant differences in mean values of CSA in three leg positions regardless of the measurement level. The largest mean CSA (114 mm2±35 mm2) was found at the proximal level in the frog-leg position. There was a significant association of the CSA with sex and height. The CSA in males was greater than in females in all leg positions at the level of 20 mm caudally to the inguinal crease, while 20 mm caudally to the inguinal ligament the CSA was larger in females. The CSA of 25% of the femoral vein was smaller than 45.0 mm2 at the proximal level, and 31.5 mm2 at the distal level, which refers to diameters of 5.3 mm, and 4.5 mm, respectively. Conclusions: The cross-sectional area of the femoral vein is the largest in the frog-leg position, and depends on gender.
MeSH term(s)	Adult ; Demography ; Female ; Femoral Vein/physiology ; Humans ; Ligaments, Articular/physiology ; Male ; Posture/physiology ; Young Adult
Language	English
Publishing date	2017
Publishing country	United States
Document type	Journal Article
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0182623
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Article: Ultrasound assessment of the jugular and vertebral veins in healthy individuals: selected physiological aspects and morphological parameters.

Czyżewska, Dorota / Krysiuk, Kamil / Dobrzycki, Konrad / Ustymowicz, Andrzej

Journal of ultrasonography

2015 Volume 15, Issue 62, Page(s) 267–273

Abstract: Aim: Ultrasound assessment of morphological parameters of the internal jugular veins and vertebral veins in healthy individuals as well as their dependence on the patient's position.: Material: The examinations were conducted in 185 healthy ... ...

Abstract	Aim: Ultrasound assessment of morphological parameters of the internal jugular veins and vertebral veins in healthy individuals as well as their dependence on the patient's position. Material: The examinations were conducted in 185 healthy individuals (101 females and 84 males) aged 18-89. Ultrasound examinations were conducted with the use of a linear probe with the frequency of 5-9 MHz in the supine (0°) and sitting position (90°). Results: In 154 cases (83.2%) on the left side and in 150 cases (81.1%) on the right side, the jugular veins were completely closed in the sitting position. In 31 cases (16.8%) on the left side and in 35 cases (18.9%) on the right side, they were merely narrowed. By contrast with the jugular veins, the cross-sectional area (CSA) of the vertebral veins was greater in the sitting position than in the supine position in a statistically significant way. The CSA values of the jugular veins in the supine position ranged from 0 cm(2) to 4.3 cm(2). There were no statistically significant differences in the CSA between men and women. The cross-sectional area of the right jugular vein in the supine position was greater in a statistically significant way than that of the left jugular vein. In this study population, the ratio of the cross-sectional areas of the jugular veins on both sides amounted to 8.5:1. Conclusions: The width of the jugular and vertebral veins significantly varies depending on the patient's position. The range of the CSA values for the jugular veins is broad, which should be taken into account when interpreting imaging findings. The internal jugular veins can show considerable asymmetry.
Language	English
Publishing date	2015-09-30
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2843824-3
ISSN	2084-8404
ISSN	2084-8404
DOI	10.15557/JoU.2015.0023
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Article ; Online: Internal jugular veins must be measured before catheterization.

Czyzewska, Dorota / Ustymowicz, Andrzej / Kosel, Juliusz

Journal of clinical anesthesia

2015 Volume 27, Issue 2, Page(s) 129–131

Abstract: Study objective: The study objective is to determine the cross-sectional area (CSA) of the right and left internal jugular vein (IJV) in supine position in healthy subjects.: Design: This is a prospective, nonrandomized study.: Setting: The ... ...

Abstract	Study objective: The study objective is to determine the cross-sectional area (CSA) of the right and left internal jugular vein (IJV) in supine position in healthy subjects. Design: This is a prospective, nonrandomized study. Setting: The setting is a university hospital. Patients: The patients are 185 consenting healthy subjects. Interventions: B-mode ultrasonography examinations of the right and left IJV were performed with the use of a linear 14-MHz transducer at the level of the cricoid cartilage. The CSA of the examined vessels was measured in a supine position. Measurements and main results: The CSA on both sides differed by up to 850%. There were no statistically significant differences between CSA of IJVs in men and women. The CSA of the IJV on the right side was significantly greater than on the left side. The right IJV was more often classified as the "dominant" vessel (CSA being more than twice as large as the opposite side). A "small" vessel (CSA ≤ 0.4 cm(2)) was found in 54 cases (14.6%). In 9 subjects (4.9%), they were detected bilaterally. Conclusion: The CSA of IJVs varies widely. Although the CSA was found to be often greater on the right than on the left side, a "small" vessel may occur on both sides.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Catheterization, Central Venous/methods ; Female ; Humans ; Jugular Veins/anatomy & histology ; Jugular Veins/diagnostic imaging ; Male ; Middle Aged ; Prospective Studies ; Reference Values ; Supine Position ; Ultrasonography ; Young Adult
Language	English
Publishing date	2015-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	1011618-7
ISSN	1873-4529 ; 0952-8180
ISSN (online)	1873-4529
ISSN	0952-8180
DOI	10.1016/j.jclinane.2014.09.010
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