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  1. Book: Neglected Tropical Diseases - Europe and Central Asia

    Utzinger, Jürg / Steinmann, Peter

    (Neglected Tropical Diseases)

    2022  

    Author's details Dr. Steinmann and Dr. Utzinger have dedicated their careers to the epidemiology and control of NTDs, with an emphasis on soil-transmitted helminthiases, schistosomiasis, food-borne trematodiases and leprosy. They are leading experts in their respective fields and share their experience from decades of work in Africa, Asia, Europe and Latin America with students, as advisors and through numerous scientific publications
    Series title Neglected Tropical Diseases
    Keywords Cysticercosis ; echinococcosis ; Leishmaniasis ; soil-transmitted helminthiasis ; travel medicine ; cysticercosis ; leishmaniasis
    Language English
    Size 192 p.
    Edition 1
    Publisher Springer International Publishing
    Document type Book
    Note PDA Manuell_13
    Format 160 x 241 x 17
    ISBN 9783030842222 ; 3030842223
    Database PDA

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  2. Book ; Online ; E-Book: Neglected Tropical Diseases - East Asia

    Utzinger, Jürg / Yap, Peiling / Bratschi, Martin / Steinmann, Peter

    (Neglected tropical diseases)

    2019  

    Author's details Jürg Utzinger, Peiling Yap, Martin Bratschi, Peter Steinmann editors
    Series title Neglected tropical diseases
    Keywords Medical parasitology ; Emerging infectious diseases ; Tropical medicine ; Microbiology
    Subject code 616.96
    Language English
    Size 1 Online-Ressource (V, 173 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020133748
    ISBN 978-3-030-12008-5 ; 9783030120061 ; 3-030-12008-2 ; 3030120066
    DOI 10.1007/978-3-030-12008-5
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  3. Article: Editorial : Swiss TPH: 30 Years of R&D Towards New Drugs for Tropical Diseases.

    Utzinger, Jürg / Mäser, Pascal

    Chimia

    2023  Volume 77, Issue 9, Page(s) 570–571

    Abstract: The year 2023 marks the 80th anniversary of the Swiss Tropical and Public Health Institute (Swiss TPH). Associated with the University of Basel, Swiss TPH combines research, education and services, working across a value chain from innovation and ... ...

    Abstract The year 2023 marks the 80th anniversary of the Swiss Tropical and Public Health Institute (Swiss TPH). Associated with the University of Basel, Swiss TPH combines research, education and services, working across a value chain from innovation and validation to application to improve people's health and well-being. Around 700 staff and students work in Swiss TPH's new headquarters in an emerging life-science cluster in Allschwil, Switzerland, focusing on infectious and non-communicable diseases, environment, society and health as well as health systems and interventions. In this special issue of Chimia, we highlight 30 years of research and development (R&D) at Swiss TPH, deeply grounded in partnership, towards new drugs for tropical diseases.
    MeSH term(s) Humans ; Switzerland ; Research ; Biological Science Disciplines ; Public Health ; Students
    Language English
    Publishing date 2023-09-20
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 1516-7
    ISSN 0009-4293
    ISSN 0009-4293
    DOI 10.2533/chimia.2023.570
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 4.5: Show issues

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  4. Article: Prospects and Perspectives of Health Impact Assessment: A Systematic Review of the Peer-Reviewed Literature From June 2007 to January 2023.

    Lamprecht, Nina / Erlanger, Tobias E / Utzinger, Jürg / Winkler, Mirko S

    Public health reviews

    2024  Volume 45, Page(s) 1606649

    Abstract: Objectives: In 2008, an analysis investigating health impact assessment (HIA) practice found that only 6% of HIA-related peer-reviewed publications had a focus on low- and medium-developed countries, whereas 94% were conducted in countries with a high ... ...

    Abstract Objectives: In 2008, an analysis investigating health impact assessment (HIA) practice found that only 6% of HIA-related peer-reviewed publications had a focus on low- and medium-developed countries, whereas 94% were conducted in countries with a high or very high development state. We aimed to update and deepen these observations.
    Methods: We conducted a systematic review, searching PubMed and Web of Science for HIA-related papers published in the scientific literature from June 2007 to January 2023. Only applied HIA and papers with HIA as a subject were included.
    Results: The search yielded 3,036 publications and the final selection consisted of 1,019 publications. The annual number of total publications increased considerably over the past 15 years. Whereas research-driven HIA (
    Conclusion: The gap between the number of HIA-related peer-reviewed publications focusing on low/medium and high/very high developed countries has diminished from 6/94 to 11/89. There is a growing tendency to apply the terminology HIA for health impact modelling studies and quantitative health risk assessments.
    Language English
    Publishing date 2024-04-16
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 217531-9
    ISSN 2107-6952 ; 0301-0422
    ISSN (online) 2107-6952
    ISSN 0301-0422
    DOI 10.3389/phrs.2024.1606649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 954: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Clonorchiasis and opisthorchiasis: epidemiology, transmission, clinical features, morbidity, diagnosis, treatment, and control.

    Qian, Men-Bao / Keiser, Jennifer / Utzinger, Jürg / Zhou, Xiao-Nong

    Clinical microbiology reviews

    2024  Volume 37, Issue 1, Page(s) e0000923

    Abstract: Clonorchis ... ...

    Abstract Clonorchis sinensis
    MeSH term(s) Animals ; Humans ; Opisthorchiasis/diagnosis ; Opisthorchiasis/drug therapy ; Opisthorchiasis/epidemiology ; Clonorchiasis/diagnosis ; Clonorchiasis/drug therapy ; Clonorchiasis/epidemiology ; Clonorchis sinensis ; Opisthorchis ; Morbidity
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 645015-5
    ISSN 1098-6618 ; 0893-8512
    ISSN (online) 1098-6618
    ISSN 0893-8512
    DOI 10.1128/cmr.00009-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2409: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: [No title information]

    Flahault, Antoine / Choirat, Christine / Utzinger, Jürg

    Revue medicale suisse

    2023  Volume 19, Issue 836, Page(s) 1387–1388

    Title translation La Suisse, acteur incontournable de la santé globale.
    MeSH term(s) Humans ; Global Health ; Switzerland
    Language French
    Publishing date 2023-07-11
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    DOI 10.53738/REVMED.2023.19.836.1387
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Relative effects of climate factors and malaria control interventions on changes of parasitaemia risk in Burkina Faso from 2014 to 2017/2018.

    Traoré, Nafissatou / Singhal, Taru / Millogo, Ourohiré / Sié, Ali / Utzinger, Jürg / Vounatsou, Penelope

    BMC infectious diseases

    2024  Volume 24, Issue 1, Page(s) 166

    Abstract: Background: In Burkina Faso, the prevalence of malaria has decreased over the past two decades, following the scale-up of control interventions. The successful development of malaria parasites depends on several climatic factors. Intervention gains may ... ...

    Abstract Background: In Burkina Faso, the prevalence of malaria has decreased over the past two decades, following the scale-up of control interventions. The successful development of malaria parasites depends on several climatic factors. Intervention gains may be reversed by changes in climatic factors. In this study, we investigated the role of malaria control interventions and climatic factors in influencing changes in the risk of malaria parasitaemia.
    Methods: Bayesian logistic geostatistical models were fitted on Malaria Indicator Survey data from Burkina Faso obtained in 2014 and 2017/2018 to estimate the effects of malaria control interventions and climatic factors on the temporal changes of malaria parasite prevalence. Additionally, intervention effects were assessed at regional level, using a spatially varying coefficients model.
    Results: Temperature showed a statistically important negative association with the geographic distribution of parasitaemia prevalence in both surveys; however, the effects of insecticide-treated nets (ITNs) use was negative and statistically important only in 2017/2018. Overall, the estimated number of infected children under the age of 5 years decreased from 704,202 in 2014 to 290,189 in 2017/2018. The use of ITNs was related to the decline at national and regional level, but coverage with artemisinin-based combination therapy only at regional level.
    Conclusion: Interventions contributed more than climatic factors to the observed change of parasitaemia risk in Burkina Faso during the period of 2014 to 2017/2018. Intervention effects varied in space. Longer time series analyses are warranted to determine the differential effect of a changing climate on malaria parasitaemia risk.
    MeSH term(s) Child ; Humans ; Infant ; Child, Preschool ; Burkina Faso/epidemiology ; Bayes Theorem ; Malaria/epidemiology ; Malaria/prevention & control ; Malaria/parasitology ; Logistic Models ; Climate ; Parasitemia/epidemiology ; Parasitemia/prevention & control ; Insecticides/pharmacology
    Chemical Substances Insecticides
    Language English
    Publishing date 2024-02-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041550-3
    ISSN 1471-2334 ; 1471-2334
    ISSN (online) 1471-2334
    ISSN 1471-2334
    DOI 10.1186/s12879-024-08981-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Operational Differences between Product Development Partnership, Pharmaceutical Industry, and Investigator Initiated Clinical Trials.

    Nebie, Eric I / van Eeuwijk, Peter / Sawadogo, Hélène N / Reus, Elisabeth / Utzinger, Jürg / Burri, Christian

    Tropical medicine and infectious disease

    2024  Volume 9, Issue 3

    Abstract: Medicine development is a lengthy endeavour. Increasing regulatory stringency and trial complexity might lead to reduced efficiency, dwindled output, and elevated costs. However, alternative models are possible. We compared the operational differences ... ...

    Abstract Medicine development is a lengthy endeavour. Increasing regulatory stringency and trial complexity might lead to reduced efficiency, dwindled output, and elevated costs. However, alternative models are possible. We compared the operational differences between pharmaceutical industry sponsored trials, product development partnership trials, and investigator-initiated trials to identify key drivers of inefficiency in clinical research. We conducted an exploratory mixed-methods study with stakeholders, including clinical trial sponsors, contract research organisations, and investigators. The qualitative component included 40 semi-structured interviews, document reviews of 12 studies and observations through work shadowing in research institutions in Burkina Faso, Mali, and Switzerland. The findings were triangulated with an online survey polling clinical research professionals. The operational differences were grouped under five categories: (i) trial start-up differences including governance and management structure; (ii) study complexity; (iii) site structural and organisational differences; (iv) study conduct, quality approaches, and standard operating procedures; and (v) site capacity strengthening and collaboration. Early involvement of sites in the planning and tailored quality approaches were considered critical for clinical operations performance. Differences between the types of trials reviewed pertained to planning, operational complexities, quality approaches, and support to the sites. Integration of quality-by-design components has the potential to alleviate unnecessary process burden.
    Language English
    Publishing date 2024-02-29
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2414-6366
    ISSN (online) 2414-6366
    DOI 10.3390/tropicalmed9030056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Schistosomiasis at the Crossroad to Elimination: Review of Eclipsed Research with Emphasis on the Post-Transmission Agenda.

    Giboda, Michal / Bergquist, Robert / Utzinger, Jürg

    Tropical medicine and infectious disease

    2022  Volume 7, Issue 4

    Abstract: While chronic schistosomiasis is pathologically well defined, the acute form of the disease is less well understood. It is generally agreed that early lesions, such as lung nodules and bladder polyps, are reversible, which impedes identification of the ... ...

    Abstract While chronic schistosomiasis is pathologically well defined, the acute form of the disease is less well understood. It is generally agreed that early lesions, such as lung nodules and bladder polyps, are reversible, which impedes identification of the time elapsed since exposure. The intermediate stage between the acute and the chronic forms of schistosomiasis requires further investigation, as does the clinical stage due to lesions remaining after treatment. With current schistosomiasis control efforts gradually progressing to elimination, there is a need to focus on post-transmission schistosomiasis, which not only refers to remaining lesions from previous infections, but also accounts for the potential presence of surviving worms after treatment. This issue is particularly salient for migrants from endemic to non-endemic countries and should be kept in mind for returning expatriates from schistosomiasis-endemic countries. Negative stool examination or urine filtration are generally taken as indicative of cure since rectoscopy for
    Language English
    Publishing date 2022-03-31
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2414-6366
    ISSN (online) 2414-6366
    DOI 10.3390/tropicalmed7040055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: An index of access to essential infrastructure to identify where physical distancing is impossible.

    Günther, Isabel / Harttgen, Kenneth / Seiler, Johannes / Utzinger, Jürg

    Nature communications

    2022  Volume 13, Issue 1, Page(s) 3355

    Abstract: To identify areas at highest risk of infectious disease transmission in Africa, we develop a physical distancing index (PDI) based on the share of households without access to private toilets, water, space, transportation, and communication technology ... ...

    Abstract To identify areas at highest risk of infectious disease transmission in Africa, we develop a physical distancing index (PDI) based on the share of households without access to private toilets, water, space, transportation, and communication technology and weight it with population density. Our results highlight that in addition to improving health systems, countries across Africa, especially in the western part of Africa, need to address the lack of essential domestic infrastructure. Missing infrastructure prevents societies from limiting the spread of communicable diseases by undermining the effectiveness of governmental regulations on physical distancing. We also provide high-resolution risk maps that show which regions are most limited in protecting themselves. We find considerable spatial heterogeneity of the PDI within countries and show that it is highly correlated with detected COVID-19 cases. Governments could pay specific attention to these areas to target limited resources more precisely to prevent disease transmission.
    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; Communicable Diseases ; Government ; Humans ; Physical Distancing ; Transportation
    Language English
    Publishing date 2022-06-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-022-30812-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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