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Article ; Online: Nematicidal activity of native Bacillus thuringiensis against the root knot nematode, Meloidogyne incognita (Kofoid and White)

A. Ramalakshmi / R. Sharmila / M. Iniyakumar / V. Gomathi

Egyptian Journal of Biological Pest Control, Vol 30, Iss 1, Pp 1-

2020 Volume 9

Abstract: Abstract In this study, potential of the native Bacillus thuringiensis Berliner was investigated against the root knot nematode, Meloidogyne incognita (Kofoid and White) under laboratory and greenhouse conditions. Fourteen out of 50 Bt isolates obtained ... ...

Abstract	Abstract In this study, potential of the native Bacillus thuringiensis Berliner was investigated against the root knot nematode, Meloidogyne incognita (Kofoid and White) under laboratory and greenhouse conditions. Fourteen out of 50 Bt isolates obtained from root zone of vegetable crops of north western zone of Tamil Nadu, India, were found to be encoded with nematicidal cry genes, confirmed by gene-specific PCR. Nine different Cry protein profiles were obtained from native Bt. Spore-crystal mixtures of 6 isolates out of 14 (at 0.5%) showed 100% inhibition to J2 juveniles emergence from egg masses of M. incognita within 72 h of treatment. Analysis by SEM revealed that fluffy egg masses were observed in untreated samples due to hatching, whereas egg masses were covered by gelatinous matrix, when treated with spore-crystal mixture of nematicidal Bt. Two (BC and BD) of the 6 isolates were selected based on their highest nematicidal activity against J2 of M. incognita with LC50 values of 0.12 and 0.23 μg/ml of protein. The spore-crystal mixtures of isolates BC and BD when applied to tomato plants under greenhouse conditions exhibited the enhanced biocontrol potential by suppressing number of egg masses, reduction of female population and decreased root gall index, when compared to control and chemical treatments.
Keywords	Bacillus thuringiensis ; nematicidal cry genes ; Meloidogyne incognita ; Biological control ; Agriculture ; S
Subject code	580
Language	English
Publishing date	2020-07-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Lipid and renal profile in assessing the severity of alcoholic liver disease.

G, Chitrasivasankari / V, Gomathi / R, Nachiappan / Kaarthikeyan, Gurumoorthy / S, Mahalakshmi

Bioinformation

2022 Volume 18, Issue 10, Page(s) 1036–1040

Abstract: Lipid and Renal dysfunction in Alcoholic liver disease (ALD) patients occurs either due to multi-organ involvement or secondary to alcoholism. This study was conducted to evaluate the role of lipid and renal parameters in assessing the severity of ... ...

Abstract	Lipid and Renal dysfunction in Alcoholic liver disease (ALD) patients occurs either due to multi-organ involvement or secondary to alcoholism. This study was conducted to evaluate the role of lipid and renal parameters in assessing the severity of progression of ALD. Sixty cases of ALD (two groups based on compensated and decompensated features) and thirty healthy controls for comparison were included. Lipid profile (Total Cholesterol, LDL, HDL and Triglycerides) and renal parameters (serum urea, creatinine and uric acid), total and direct bilirubin, total protein and albumin were measured using automated chemistry analyzer. There was a significant decrease in Total cholesterol ,LDL and HDL levels and increased triglycerides when compared to controls (mean of 128.4 ± 59 vs 155 ± 27.2, 77 ± 44.3 vs 97.4 ± 27.2, 28.3 ± 18 vs 39.5 ± 14.1 and 115.8 ± 70.4 vs 91 ± 38 mg/dL respectively). Lipid profile showed a linear decrease while progressing from compensated to decompensated ALD. Renal parameters revealed a statistically significant decrease in serum urea ,increased creatinine and uric acid levels when compared to controls (17.57±2.96 vs23.73±4.94, 1.12±0.55 vs0.88±0.16,6.60±1.32 vs 4.68±1.40 mg/dL respectively).Total cholesterol and HDL showed a linear decrease when ALD progresses. Serum uric acid showed an early increase in compensated stage of ALD. This study inferred that Total cholesterol, TGL, HDL and uric acid can be used for assessing the severity of progression of ALD.
Language	English
Publishing date	2022-10-31
Publishing country	Singapore
Document type	Journal Article
ZDB-ID	2203786-X
ISSN	0973-2063
ISSN	0973-2063
DOI	10.6026/973206300181036
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Article: Blood ordering and utilization in patients undergoing elective general surgery procedures in a tertiary care hospital: A prospective audit.

Shaikh, Oseen H / Bhattarai, Sandeep / Shankar, V Gomathi / Basavarajegowda, Abhishekh

The National medical journal of India

2022 Volume 35, Issue 2, Page(s) 68–73

Abstract: Background Blood ordering is commonly done for patients undergoing major elective surgery. Excessive order of the blood for elective surgery leads to wastage of resources, time and workforce. Auditing preoperative blood ordering decreases the cost of ... ...

Abstract	Background Blood ordering is commonly done for patients undergoing major elective surgery. Excessive order of the blood for elective surgery leads to wastage of resources, time and workforce. Auditing preoperative blood ordering decreases the cost of medical care by avoiding unnecessary cross-match without compromising patient safety. Methods For this hospital-based audit, we collected data prospectively from July 2017 to June 2018 regarding the transfusion and transfusion indices, namely cross-match-totransfusion ratio (C/T ratio), transfusion probability (T%), transfusion index (TI) and maximum surgical blood ordering schedule (MSBOS) for elective surgeries done in the Department of Surgery. Results A total of 1151 patients were included in the study. A total of 160 units of blood were issued of which only 138 were transfused to 116 patients. Seventy-one procedures were included in the study. The C/T ratio was less than 2.5 for 16 procedures, T% was >50% for 9 procedures and MSBOS was more than 0.5 for 16 procedures. Conclusion Cross-matching is overused for elective surgical procedures. Only 16 of the 71 procedures had an ideal C/T ratio. Group and screen policy can be adopted for most of the commonly performed procedures, and cross-matching of blood may not be needed.
MeSH term(s)	Humans ; Elective Surgical Procedures ; Tertiary Care Centers ; Patient Safety ; Policy ; Workforce
Language	English
Publishing date	2022-12-03
Publishing country	India
Document type	Journal Article
ZDB-ID	645116-0
ISSN	0970-258X
ISSN	0970-258X
DOI	10.25259/NMJI_543_19
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Article: Determining the Best Thyroid Imaging Reporting and Data System: A Prospective Study Comparing the Diagnostic Performance of ACR, EU, and K TIRADS in the Evaluation of Thyroid Nodules.

Mohan, Supraja Laguduva / Govindarajalou, Ramkumar / Naik, Dukhabandhu / Saxena, Sunil Kumar / Toi, Pampa Ch / V, Gomathi Shankar

The Indian journal of radiology & imaging

2023 Volume 34, Issue 2, Page(s) 220–231

Abstract: ... ...

Abstract	Background
Language	English
Publishing date	2023-10-13
Publishing country	Germany
Document type	Journal Article
ZDB-ID	605869-3
ISSN	0971-3026 ; 0970-2016
ISSN	0971-3026 ; 0970-2016
DOI	10.1055/s-0043-1775862
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Article: Determining the Best Thyroid Imaging Reporting and Data System: A Prospective Study Comparing the Diagnostic Performance of ACR, EU, and K TIRADS in the Evaluation of Thyroid Nodules

Mohan, Supraja Laguduva / Govindarajalou, Ramkumar / Naik, Dukhabandhu / Saxena, Sunil Kumar / Toi, Pampa Ch. / V., Gomathi Shankar

Indian Journal of Radiology and Imaging

2023 Volume 34, Issue 02, Page(s) 220–231

Abstract: Background: Many different risk stratification systems have been formulated for thyroid nodules, differing in their fine-needle aspiration cytology (FNAC) indication, suggesting a lack of consensus around the world.: Purpose: This prospective study ... ...

Abstract	Background: Many different risk stratification systems have been formulated for thyroid nodules, differing in their fine-needle aspiration cytology (FNAC) indication, suggesting a lack of consensus around the world. Purpose: This prospective study was conducted to find the best guideline for risk stratification, for a better malignancy yield, and with reduced rates of negative FNACs among three Thyroid Imaging, Reporting, and Data System (TIRADS) guidelines. Materials and Methods: A total of 625 thyroid nodules with conclusive FNAC or histopathological diagnosis were included in the study. Various sonographic parameters were recorded. They were classified into categories as per the three guidelines and compared with FNAC diagnosis. The guidelines were evaluated in terms of sensitivity, specificity, predictive values, and diagnostic accuracy. Sensitivity and specificity were compared by McNemar's test. Results: American College of Radiology (ACR) TIRADS had the highest diagnostic accuracy (56.8%), specificity (50.75%), positive predictive value (23.92%), lowest rates of negative FNACs (76.08%), and high negative predictive value (97.84 %). Korean (K) TIRADS had the maximum sensitivity (97.75%), highest negative predictive value (98.44%), and gross malignancy yield. European TIRADS was between the two other guidelines in most parameters with specificity like K TIRADS. Conclusion: All the three guidelines are very good screening tools, with comparable high sensitivity. ACR TIRADS is better in terms of specificity and reduced rates of negative FNACs. Including the presence of a suspicious cervical lymph node as a criterion and more frequent follow-up might further improve the diagnostic performance of the guideline.
Keywords	thyroid nodules ; Thyroid Imaging Reporting and Data System ; TIRADS ; thyroid ultrasound ; American College of Radiology ; Korean Society of Thyroid Radiology ; European Thyroid Association ; fine-needle aspiration cytology
Language	English
Publishing date	2023-10-13
Publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	605869-3
ISSN	1998-3808 ; 0971-3026 ; 0970-2016
ISSN (online)	1998-3808
ISSN	0971-3026 ; 0970-2016
DOI	10.1055/s-0043-1775862
Database	Thieme publisher's database

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Article ; Online: Proceedings of the 3rd Indian Cancer Genome Atlas Conference 2022: Biobanking to Omics: Collecting the Global Experience.

Joshi, Sneha / Mishra, Rupa / Kulkarni, Madhura / Kelkar, Devaki A / Harikrishnan, Keerthi / Vaid, Pooja / V, Gomathi / John, Jisha / Tamhane, Siddhi / Deshpande, Anand / Badve, Sunil / Chintamani / Mehrotra, Ravi / Shashidhara, L S / Kothari, Ashutosh / Koppiker, Chaitanyanand

JCO global oncology

2023 Volume 9, Page(s) e2200176

Abstract: On January 13th and 14th 2022, the Center for Translational Cancer Research organized the virtual third Indian Cancer Genome Atlas (ICGA) Conference 2022 "Biobanking to Omics - Collecting the Global Experience." This conference was planned as the ... ...

Abstract	On January 13th and 14th 2022, the Center for Translational Cancer Research organized the virtual third Indian Cancer Genome Atlas (ICGA) Conference 2022 "Biobanking to Omics - Collecting the Global Experience." This conference was planned as the steppingstone to help ICGA understand the road ahead and the probable roadblocks in its preparatory phase as ICGA begins to streamline the tumor tissue biobanking and multi-omics efforts in the Indian subcontinent. The first day of the conference was dedicated to updates on the current status of ICGA, the future prospect, and the global understanding of multi-omics efforts. The key highlights included two keynote speeches by Dr Wui Jin Koh, Senior Vice President and Chief Medical Office, National Comprehensive Cancer Network, and by Dr Christina Curtis, Associate Professor, Stanford University School of Medicine. The first day ended with an intriguing panel discussion on "ICGA updates and Future Steps." The second day focused on biobanking practices across the globe and several aspects of biobank setup such as infrastructure, maintenance, quality control, patient consent, and lessons learned from established biobanking setups. The talk by Rosita Kammler, Head, Translational Research Coordination, International Breast Cancer Study Group, Switzerland, and Ruhul Amin, Director, Bangladesh Medical Research Council were the key highlights. The second day also ended with an engaging panel discussion on "Tumor tissue biobanking - national and international perspectives." Overall, the conference was well received and had good attendance from national and international students, researchers, and faculty from academia as well as industry.
MeSH term(s)	Humans ; Biological Specimen Banks ; Neoplasms/genetics ; Neoplasms/therapy ; Bangladesh
Language	English
Publishing date	2023-01-19
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2687-8941
ISSN (online)	2687-8941
DOI	10.1200/GO.22.00176
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Article ; Online: ENHANCED DISTRIBUTED SERVICE MODEL FOR POWER SYSTEM STATE ESTIMATION

V.Gomathi / V.Ramachandran

International Journal on Computer Science and Engineering, Vol 3, Iss 2, Pp 481-

2011 Volume 486

Abstract: Web services are emerging technologies of choice for implementing distributed service models for performing power system operations such as state estimation of power systems in a complete secure, distributed and platform independent environment. The ... ...

Abstract	Web services are emerging technologies of choice for implementing distributed service models for performing power system operations such as state estimation of power systems in a complete secure, distributed and platform independent environment. The power system applications themselves have been developed in different platforms and language paradigms. Interoperability between power system applications becomes a major issue because of the heterogeneous nature. The main aim of this paper is to propose a model that enhances the interoperability between power system applications byrepresenting the power system data in a more flexible and language independent format (i.e.) in XML and to implement the power system operations in a highly distributed environment. The power systemstate estimation problem is considered for representation and analysis in a distributed environment. The proposed Web service model using JAX-RPC (Java API for XML-based RPC) for state estimation ishighly distributed and has inherent features such as platform ndependency, interoperability, functionreusability, discoverability and security. A generalized XML based data generation model has beenproposed for exchanging data in order to enhance the interoperability between legacy power system applications. The performance of the proposed JAX-RPC model for power system state estimation is compared with the traditional client-server and RMI models using Round Trip Time (RTT) as a measure. (The overhead associated with the proposed model).
Keywords	MODEL FOR POWER SYSTEM STATE ESTIMATION ; Electronic computers. Computer science ; QA75.5-76.95 ; Instruments and machines ; QA71-90 ; Mathematics ; QA1-939 ; Science ; Q ; DOAJ:Computer Science ; DOAJ:Technology and Engineering
Subject code	004
Language	English
Publishing date	2011-02-01T00:00:00Z
Publisher	Engg Journals Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Prophylactic antibiotics in open mesh repair of inguinal hernia - a randomized controlled trial.

Shankar, V Gomathi / Srinivasan, K / Sistla, Sarath C / Jagdish, S

International journal of surgery (London, England)

2010 Volume 8, Issue 6, Page(s) 444–447

Abstract: The role of prophylactic antibiotics in mesh repair of inguinal hernia is unclear. A Cochrane meta-analysis in 2005 concluded that "antibiotic prophylaxis for elective inguinal hernia repair cannot be firmly recommended or discarded" and "further studies ...

Abstract	The role of prophylactic antibiotics in mesh repair of inguinal hernia is unclear. A Cochrane meta-analysis in 2005 concluded that "antibiotic prophylaxis for elective inguinal hernia repair cannot be firmly recommended or discarded" and "further studies are needed, particularly on the use for mesh repair." So, we designed a study to define the role of prophylactic antibiotics in mesh repair of inguinal hernia. We conducted a prospective, randomized, double-blind, trial comparing wound infection rates in 450 patients (225 received intravenous Cefazolin, 225 received a placebo) undergoing primary inguinal hernia repair electively using polypropylene mesh. 334 patients who completed a followup period of one month were analyzed. Age, American Society of Anesthesiologists class, type of hernia, type of anesthesia, grade of surgeon, pre and postoperative hospital stay and duration of operation were recorded. CDC criteria was used to define wound infection. Groups were well matched for all preoperative variables studied. The overall infection rate was 8.7% (29 out of 334). The incidence of wound infection in antibiotic group was 7% and 10.5% in control group. One from each group developed deep surgical site infection. Most of the infections occurred between the 7th and 12th post-operative day after discharge from the hospital. Antibiotic prophylaxis was associated with decreased incidence of wound infection when compared to control group, but the difference was not statistically significant. Based on our results we do not recommend the routine use of antibiotic prophylaxis in elective mesh repair of inguinal hernias.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anti-Bacterial Agents/administration & dosage ; Antibiotic Prophylaxis/methods ; Cefazolin/administration & dosage ; Double-Blind Method ; Female ; Follow-Up Studies ; Hernia, Inguinal/surgery ; Humans ; Injections, Intravenous ; Male ; Middle Aged ; Prospective Studies ; Surgical Mesh ; Surgical Wound Infection/prevention & control ; Time Factors ; Treatment Outcome ; Young Adult
Chemical Substances	Anti-Bacterial Agents ; Cefazolin (IHS69L0Y4T)
Language	English
Publishing date	2010
Publishing country	England
Document type	Comparative Study ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	2212038-5
ISSN	1743-9159 ; 1743-9191
ISSN (online)	1743-9159
ISSN	1743-9191
DOI	10.1016/j.ijsu.2010.05.011
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