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Article ; Online: Ambulatory daytime blood pressure versus tonometric blood pressure measurements in the laboratory: effect of posture.

Värri, Emmi / Suojanen, Lauri / Koskela, Jenni K / Choudhary, Manoj K / Tikkakoski, Antti / Kähönen, Mika / Nevalainen, Pasi I / Mustonen, Jukka / Pörsti, Ilkka

Blood pressure monitoring

2023  Volume 28, Issue 4, Page(s) 199–207

Abstract: Objective: To compare blood pressure (BP) in tonometric radial artery recordings during passive head-up tilt with ambulatory recordings and evaluate possible laboratory cutoff values for hypertension.: Methods: Laboratory BP and ambulatory BP were ... ...

Abstract Objective: To compare blood pressure (BP) in tonometric radial artery recordings during passive head-up tilt with ambulatory recordings and evaluate possible laboratory cutoff values for hypertension.
Methods: Laboratory BP and ambulatory BP were recorded in normotensive (n = 69), unmedicated hypertensive (n = 190), and medicated hypertensive (n = 151) subjects.
Results: Mean age was 50.2 years, BMI 27.7 kg/m 2 , ambulatory daytime BP 139/87 mmHg, and 276 were male (65%). As supine-to-upright changes in SBP ranged from -52 to +30 mmHg, and in DBP from -21 to +32 mmHg, the mean values of BP supine and upright measurements were compared with ambulatory BP. The mean(supine+upright) systolic laboratory BP was corresponding to ambulatory level (difference +1 mmHg), while mean(supine+upright) DBP was 4 mmHg lower ( P  < 0.05) than ambulatory value. Correlograms indicated that laboratory 136/82 mmHg corresponded to ambulatory 135/85 mmHg. When compared with ambulatory 135/85 mmHg, the sensitivity and specificity of laboratory 136/82 mmHg to define hypertension were 71.5% and 77.3% for SBP, and 71.7% and 72.8%, for DBP, respectively. The laboratory cutoff 136/82 mmHg classified 311/410 subjects similarly to ambulatory BP as normotensive or hypertensive, 68 were hypertensive only in ambulatory, while 31 were hypertensive only in laboratory measurements.
Conclusion: BP responses to upright posture were variable. When compared with ambulatory BP, mean(supine+upright) laboratory cutoff 136/82 mmHg classified 76% of subjects similarly as normotensive or hypertensive. In the remaining 24% the discordant results may be attributed to white-coat or masked hypertension, or higher physical activity during out-of-office recordings.
MeSH term(s) Humans ; Male ; Middle Aged ; Female ; Blood Pressure ; Hypertension/diagnosis ; Blood Pressure Determination/methods ; Masked Hypertension ; Blood Pressure Monitoring, Ambulatory ; Posture
Language English
Publishing date 2023-06-08
Publishing country England
Document type Journal Article
ZDB-ID 1324472-3
ISSN 1473-5725 ; 1359-5237
ISSN (online) 1473-5725
ISSN 1359-5237
DOI 10.1097/MBP.0000000000000651
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