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  1. Article ; Online: Morgagni Hernia Repair in Adults: A Single-Center Experience in Spanish Population.

    Santana Valenciano, Ángela / Priego Jiménez, Pablo / Vaello Jodra, Víctor / Galindo Álvarez, Julio / Fernández Cebrián, José María

    Journal of laparoendoscopic & advanced surgical techniques. Part A

    2022  Volume 32, Issue 11, Page(s) 1161–1163

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Adult ; Humans ; Female ; Middle Aged ; Aged ; Aged, 80 and over ; Male ; Herniorrhaphy/methods ; Hernias, Diaphragmatic, Congenital/surgery ; Laparoscopy/methods ; Laparotomy/methods ; Retrospective Studies ; Surgical Mesh
    Language English
    Publishing date 2022-07-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1381909-4
    ISSN 1557-9034 ; 1092-6429
    ISSN (online) 1557-9034
    ISSN 1092-6429
    DOI 10.1089/lap.2022.0331
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Early laparoscopic cholecystectomy in oldest-old patients: a propensity score matched analysis of a nationwide registry.

    Di Martino, Marcello / Gancedo Quintana, Álvaro / Vaello Jodra, Víctor / Sanjuanbenito Dehesa, Alfonso / Morales García, Dieter / Caiña Ruiz, Rubén / García-Moreno Nisa, Francisca / Mendoza-Moreno, Fernando / Alonso Batanero, Sara / Quiñones Sampedro, José Edecio / Lora Cumplido, Paola / Arango Bravo, Altea / Rubio-Perez, Ines / Asensio-Gomez, Luis / Pardo Aranda, Fernando / Sentí Farrarons, Sara / Ruiz Moreno, Cristina / Martinez Moreno, Clara Maria / Sarriugarte Lasarte, Aingeru /
    Prieto Calvo, Mikel / Aparicio-Sánchez, Daniel / Perea Del Pozo, Eduardo Perea / Pellino, Gianluca / Martin-Perez, Elena

    Updates in surgery

    2022  Volume 74, Issue 3, Page(s) 979–989

    Abstract: The role of early laparoscopic cholecystectomy (ELC) in "oldest-old" patients with acute calculous cholecystitis (ACC) is still controversial. The aim of this study is to assess the safety of ELC for ACC in ≥ 85-year-old patients. Multicentric ... ...

    Abstract The role of early laparoscopic cholecystectomy (ELC) in "oldest-old" patients with acute calculous cholecystitis (ACC) is still controversial. The aim of this study is to assess the safety of ELC for ACC in ≥ 85-year-old patients. Multicentric retrospective study that analysed data of patients who underwent ELC for ACC between 2013 and 2018. Patients ≥ 85-year-old (oldest-old patients) were compared with younger patients, before and after propensity score matching (PSM). The main outcomes were mortality, post-operative complications, length of stay (LOS), and readmissions. The study included 1670 patients. The unmatched comparison revealed a selection bias towards the oldest-old group, which was associated with higher Charlson Comorbidity Index (5 vs 1, p < 0.001), more ASA III/IV subjects (54.2% vs 19.3%, p < 0.001), class II/III ACC (80.1% vs 69.1%, p = 0.016) and higher Chole-Risk Score (p > 0.001). The oldest-old also required more conversion to open surgery (20% vs 10.3%, p = 0.005). Postoperatively, they had a higher 90-day mortality rate (7.6% vs 1%, p < 0.001), more total complications (40.6% vs 17.7%, p < 0.001), complications ≥ IIIa Clavien-Dindo (14.4% vs 5.8%, p = 0.002), longer LOS (6 vs 5 days, p < 0.001), and more readmissions (6.6% vs 2.6%, p < 0.001). After PSM (n = 206), the two groups were comparable in terms of baseline characteristics and intraoperative outcomes. No differences were observed in post-operative complications; bile leak; incisional, intrabdominal, urinary or respiratory tract infections; LOS or readmissions. In the oldest-old, ELC for ACC is still associated with significant morbidity and mortality. However, it seems to be safe in selected patients. Therefore, age itself should not be regarded as a contraindication to ELC for ACC.
    MeSH term(s) Aged, 80 and over ; Cholecystectomy, Laparoscopic/adverse effects ; Cholecystitis, Acute/surgery ; Humans ; Length of Stay ; Postoperative Complications/epidemiology ; Postoperative Complications/surgery ; Propensity Score ; Registries ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2022-03-06
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-022-01254-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Laparoscopic cholecystectomy for acute cholecystitis: is the surgery still safe beyond the 7-day barrier? A multicentric observational study.

    Di Martino, Marcello / Mora-Guzmán, Ismael / Vaello Jodra, Víctor / Sanjuanbenito Dehesa, Alfonso / Morales-García, Dieter / Caiña Ruiz, Rubén / García-Moreno Nisa, Francisca / Mendoza-Moreno, Fernando / Alonso Batanero, Sara / Quiñones Sampedro, José Edecio / Lora Cumplido, Paola / Arango Bravo, Altea / Rubio-Perez, Ines / Asensio-Gomez, Luis / Pardo Aranda, Fernando / Sentí I Farrarons, Sara / Ruiz Moreno, Cristina / Martinez Moreno, Clara Maria / Sarriugarte Lasarte, Aingeru /
    Prieto Calvo, Mikel / Aparicio-Sánchez, Daniel / Perea Del Pozo, Eduardo / Martin-Perez, Elena

    Updates in surgery

    2020  Volume 73, Issue 1, Page(s) 261–272

    Abstract: Timing for early laparoscopic cholecystectomy (ELC) in patients with acute calculous cholecystitis (ACC) is still controversial. This study assesses ELC for ACC with delayed presentation, according to hospital volume. Multicentric retrospective analysis ... ...

    Abstract Timing for early laparoscopic cholecystectomy (ELC) in patients with acute calculous cholecystitis (ACC) is still controversial. This study assesses ELC for ACC with delayed presentation, according to hospital volume. Multicentric retrospective analysis of 1868 ELC. Patients were classified into two groups according to the timing of surgery from clinical onset and centre volume. Group 1 (G1) within the first 7 days, group 2 (G2) beyond that. Then centres were classified in low volume centres (LVC) and higher volume centres (HVC) according to the number of ELC performed per year. Overall, G2 showed increased conversion rate (17.7% vs 10.7%; p = 0.004), intraoperative complications (7.3% vs 2.9%; p = 0.001); postoperative haemorrhage (3.6% vs 0.8%; p < 0.001), infections (16.6% vs 9.3%; p = 0.003) and global complications (27.6% vs 19.8%; p = 0.011). HVC in comparison with LVC presented decreased conversion rate (17.1% vs 7.6%; p < 0.001), intraoperative bleeding (2.1% vs 1%; p = 0.047), postoperative bile leakage (4.1% vs 2.1%; p = 0.011), infectious (13.7% vs 7.5%; p < 0.001) and global complications (25.7% vs 17.1%; p < 0.001). HVC did not show an increase in any of the above-mentioned outcomes when G1 and G2 were compared. ELC must be indicated cautiously in patients with ACC and more than 1 week of symptom duration. It should be performed in centres with sufficient experience in the management of this disease.
    MeSH term(s) Cholecystectomy, Laparoscopic/adverse effects ; Cholecystectomy, Laparoscopic/statistics & numerical data ; Cholecystitis, Acute/etiology ; Cholecystitis, Acute/surgery ; Conversion to Open Surgery/statistics & numerical data ; Gallstones/complications ; Gallstones/surgery ; Hospitals/statistics & numerical data ; Intraoperative Complications/epidemiology ; Intraoperative Complications/etiology ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Prognosis ; Retrospective Studies ; Safety ; Time Factors
    Language English
    Publishing date 2020-11-22
    Publishing country Italy
    Document type Journal Article ; Multicenter Study ; Observational Study
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-020-00924-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Multicentre cohort study of acute cholecystitis management during the COVID-19 pandemic.

    Martínez Caballero, Javier / González González, Lucía / Rodríguez Cuéllar, Elías / Ferrero Herrero, Eduardo / Pérez Algar, Cristina / Vaello Jodra, Victor / Pérez Díaz, María Dolores / Dziakova, Jana / San Román Romanillos, Rosario / Di Martino, Marcello / de la Hoz Rodríguez, Ángela / Galán Martín, Mónica / Sánchez López, Daniel / García Virosta, Mariana / de la Fuente Bartolomé, Marta / Pardo de Lama, María de Mar / Gutiérrez Samaniego, María / Díaz Pérez, David / Alias Jiménez, David /
    de Nicolás Navas, Luis / Pérez Alegre, Juan José / García-Quijada García, Javier / Guevara-Martínez, Jenny / Villadoniga, Arantxa / Martínez Fernández, Roberto

    European journal of trauma and emergency surgery : official publication of the European Trauma Society

    2021  Volume 47, Issue 3, Page(s) 683–692

    Abstract: Purpose: To analyse acute cholecystitis (AC) management during the first pandemic outbreak after the recommendations given by the surgical societies estimating: morbidity, length of hospital stay, mortality and hospital-acquired SARS-CoV-2 infection ... ...

    Abstract Purpose: To analyse acute cholecystitis (AC) management during the first pandemic outbreak after the recommendations given by the surgical societies estimating: morbidity, length of hospital stay, mortality and hospital-acquired SARS-CoV-2 infection rate.
    Methods: Multicentre-combined (retrospective-prospective) cohort study with AC patients in the Community of Madrid between 1st March and 30th May 2020. 257 AC patients were involved in 16 public hospital. Multivariant binomial logistic regression (MBLR) was applied to mortality.
    Results: Of COVID-19 patients, 30 were diagnosed at admission and 12 patients were diagnosed during de admission or 30 days after discharge. In non-COVID-19 patients, antibiotic therapy was received in 61.3% of grade I AC and 40.6% of grade II AC. 52.4% of grade III AC were treated with percutaneous drainage (PD). Median hospital stay was 5 [3-8] days, which was higher in the non-surgical treatment group with 7.51 days (p < 0.001) and a 3.25% of mortality rate (p < 0.21). 93.3% of patients with SARS-CoV-2 infection at admission were treated with non-surgical treatment (p = 0.03), median hospital stay was 11.0 [7.5-27.5] days (p < 0.001) with a 7.5% of mortality rate (p > 0.05). In patients with hospital-acquired SARS-CoV-2 infection, 91.7% of grade I-II AC were treated with non-surgical treatment (p = 0.037), with a median hospital stay of 16 [4-21] days and a 18.2% mortality rate (p > 0.05). Hospital-acquired infection risk when hospital stay is > 7 days is OR 4.7, CI 95% (1.3-16.6), p = 0.009. COVID-19 mortality rate was 11.9%, AC severity adjusted OR 5.64 (CI 95% 1.417-22.64). In MBLR analysis, age (OR 1.15, CI 95% 1.02-1.31), SARS-CoV-2 infection (OR 14.49, CI 95% 1.33-157.81), conservative treatment failure (OR 8.2, CI 95% 1.34-50.49) and AC severity were associated with an increased odd of mortality.
    Conclusion: In our population, during COVID-19 pandemic, there was an increase of non-surgical treatment which was accompanied by an increase of conservative treatment failure, morbidity and hospital stay length which may have led to an increased risk hospital-acquired SARS-CoV-2 infection. Age, SARS-CoV-2 infection, AC severity and conservative treatment failure were mortality risk factors.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; COVID-19/diagnosis ; COVID-19/mortality ; COVID-19/prevention & control ; Cholecystectomy/statistics & numerical data ; Cholecystitis, Acute/diagnosis ; Cholecystitis, Acute/epidemiology ; Cholecystitis, Acute/therapy ; Cohort Studies ; Comorbidity ; Conservative Treatment/methods ; Conservative Treatment/statistics & numerical data ; Cross Infection/epidemiology ; Cross Infection/virology ; Drainage/methods ; Drainage/statistics & numerical data ; Female ; Humans ; Infection Control/methods ; Infection Control/organization & administration ; Infection Control/standards ; Length of Stay/statistics & numerical data ; Male ; Middle Aged ; Outcome and Process Assessment, Health Care ; Risk Assessment ; SARS-CoV-2 ; Spain/epidemiology
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-03-19
    Publishing country Germany
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2275480-5
    ISSN 1863-9941 ; 1863-9933
    ISSN (online) 1863-9941
    ISSN 1863-9933
    DOI 10.1007/s00068-021-01631-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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