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  1. Article ; Online: Proposing the potential of utilizing the CAT score for early detection of COPD in asymptomatic patients, shifting towards a patient-centered approach: A review.

    Vaezi, Atefeh / Mirsaeidi, Mehdi

    Medicine

    2024  Volume 103, Issue 15, Page(s) e37715

    Abstract: Chronic obstructive pulmonary disease (COPD) constitutes a significant public health challenge, with delayed diagnosis and underdiagnosis being pervasive issues. The United States Preventive Service Task Force recommends restricting COPD screening to ... ...

    Abstract Chronic obstructive pulmonary disease (COPD) constitutes a significant public health challenge, with delayed diagnosis and underdiagnosis being pervasive issues. The United States Preventive Service Task Force recommends restricting COPD screening to symptomatic smokers, a focus that has exhibited limitations, leading to delayed diagnoses, and imposing a substantial burden on patients, their families, and the healthcare system. This paper explores an alternative approach, highlighting the potential utility of the COPD assessment test (CAT) score as a prescreening tool. A CAT score of 10 or higher could serve as an appropriate threshold for further diagnostic procedures, given its robust correlation with pulmonary function test parameters and is valuable capacity to quantify patients' symptoms. The utilization of CAT as a prescreening tool in primary care signifies a transition towards a more patient-centered and comprehensive approach to COPD diagnosis and care.
    MeSH term(s) Humans ; Advisory Committees ; Early Diagnosis ; Patient-Centered Care ; Pulmonary Disease, Chronic Obstructive/diagnosis
    Language English
    Publishing date 2024-04-12
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000037715
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A qualitative report on experiences of participants in the young innovative leadership program.

    Vaezi, Atefeh / Khoshgoftar, Mohadeseh / Teimouri-Jervekani, Zahra / Haghjooy Javanmard, Shaghayegh

    BMC medical education

    2024  Volume 24, Issue 1, Page(s) 71

    Abstract: Background: Leadership in health system is a universal challenge. The Young Innovative Leadership Program (YILP) designed for undergraduate and postgraduate medical sciences students, implemented at the Isfahan University of Medical Sciences, aimed to ... ...

    Abstract Background: Leadership in health system is a universal challenge. The Young Innovative Leadership Program (YILP) designed for undergraduate and postgraduate medical sciences students, implemented at the Isfahan University of Medical Sciences, aimed to cultivate leadership capacities through a 16-week training program. This program comprises ten modules covering innovation, change leadership, and management skills, with mentor-facilitated group discussions. This study aimed to provide a qualitative report of the experiences of participants in the YILP.
    Methods: A qualitative study was conducted in 2022, three months after the end of the training program, to investigate the participants' perspectives. Data was extracted through in-depth, semi-structured interviews with 14 participants.
    Results: In this study 14 undergraduate and postgraduate medical sciences students who had participated in the YILP the previous year were included. Four main categories emerged from the interviews: "emergence of new horizons", "values as beacon", "an expanded toolbox", and "program's structure: a learning atmosphere".
    Conclusions: The results of our study indicated that medical science students would benefit from leadership development programs. In this regard, the framework utilized to implement YILP could serve as a role model.
    MeSH term(s) Humans ; Curriculum ; Leadership ; Qualitative Research ; Learning
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2044473-4
    ISSN 1472-6920 ; 1472-6920
    ISSN (online) 1472-6920
    ISSN 1472-6920
    DOI 10.1186/s12909-024-05033-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: COVID-19 Vaccines Cost-Effectiveness Analysis: A Scenario for Iran.

    Vaezi, Atefeh / Meysamie, Alipasha

    Vaccines

    2021  Volume 10, Issue 1

    Abstract: COVID-19 vaccines are supposed to be critical measure for ending the pandemic. Governments had to decide on the type of vaccine to provide for their population. In this decision-making process, cost-effectiveness analysis is considered a helpful tool. ... ...

    Abstract COVID-19 vaccines are supposed to be critical measure for ending the pandemic. Governments had to decide on the type of vaccine to provide for their population. In this decision-making process, cost-effectiveness analysis is considered a helpful tool. This study is a cost-effectiveness analysis utilized to calculate the incremental cost per averted disability-adjusted life year (DALY) by vaccination compared to no vaccination for different COVID-19 vaccines. The incremental cost-effectiveness ratio (ICER) for a vaccination with COVID-19 vaccines was estimated at 6.2 to 121.2 USD to avert one DALY and 566.8 to 10,957.7 USD per one death. The lowest and highest ICERs belong to Ad26.COV2.S and CoronaVac, respectively. Considering the scenario of Iran, vaccines that are recommended include ad26.cov2.s, chadox1-S, rAd26-S + rAd5-S, and BNT162b2 in the order of recommendation.
    Language English
    Publishing date 2021-12-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10010037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Mental Health of Healthcare Workers During the Third Wave of the COVID-19 Pandemic: Did We Forget them after the First Wave?

    Saeri, Mahdieh / Vaezi, Atefeh / Tavakolifard, Negah / Haghjooy Javanmard, Shaghayegh

    Advanced biomedical research

    2023  Volume 12, Page(s) 266

    Abstract: Background: Since December 2019, countries experienced different numbers of COVID-19 pandemic waves. The COVID-19 pandemic led to adverse psychologic problems in the communities and among healthcare workers (HCWs), but the dynamic of these problems ... ...

    Abstract Background: Since December 2019, countries experienced different numbers of COVID-19 pandemic waves. The COVID-19 pandemic led to adverse psychologic problems in the communities and among healthcare workers (HCWs), but the dynamic of these problems through different waves needs to be established more.
    Materials and methods: This cross-sectional study was conducted in October 2020, through the third wave of the COVID-19 pandemic, in Isfahan, Iran. We studied HCWs' depression, anxiety, and stress using Depression, Anxiety, Stress Scale-21 (DASS-21) and insomnia using Insomnia Severity Index (ISI) questionnaires. Multiple linear regression was used to evaluate the association of some characteristic factors with different psychologic symptoms.
    Results: Our results showed that about 80% of HCWs had one or more psychological problems. The prevalence of depression, anxiety, stress, and insomnia was 46.0%, 50.2%, 44.6%, and 66.5%, respectively. Female sex, working in ICU, and having a history of chronic disease were predictors of psychological symptoms in our participants.
    Conclusion: HCWs' mental health state could be underestimated or neglected. The third pandemic wave negatively affected the mental health of the HCWs. Since mental health problems of HCWs may reduce the quality of care, the potential impact of not addressing this issue should be highlighted.
    Language English
    Publishing date 2023-11-29
    Publishing country India
    Document type Journal Article
    ZDB-ID 2672524-1
    ISSN 2277-9175
    ISSN 2277-9175
    DOI 10.4103/abr.abr_439_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Importance of the COVID-19 Vaccine Booster Dose in Protection and Immunity.

    Abdollahi, Alireza / Afsharyzad, Yeganeh / Vaezi, Atefeh / Meysamie, Alipasha

    Vaccines

    2022  Volume 10, Issue 10

    Abstract: Background: There is debate on the necessity of booster doses of COVID-19 vaccination, especially in countries with limited resources.: Methods: This cross-sectional study was conducted in a referral laboratory in Tehran, Iran. The level of COVID-19 ... ...

    Abstract Background: There is debate on the necessity of booster doses of COVID-19 vaccination, especially in countries with limited resources.
    Methods: This cross-sectional study was conducted in a referral laboratory in Tehran, Iran. The level of COVID-19 antibodies was measured and compared between individuals regarding the number of COVID-19 vaccine shots.
    Results: In this study, 176 individuals with a mean age of 36.3 (±11.7) years participated. A total of 112 individuals received two doses of the COVID-19 vaccine, and 64 individuals received three doses. Level of all antibodies was higher in those who received three doses than in those who received two doses of the COVID-19 vaccine. Considering the SARS-CoV-2 Spike IgG, the difference was not statistically significant but for the SARS-CoV-2 RBD IgG and SARS-CoV-2 NAB the difference was statistically significant. Regarding to the background variables, receiving influenza vaccine in the past year, history of autoimmune diseases and past medical history of chicken pox showed a significant association with the number of vaccine doses received. Their effects on the outcome variables assessed with multivariate logistic regression analysis.
    Conclusion: The results of our study show that a booster dose of the COVID-19 vaccine enhances the antibody response.
    Language English
    Publishing date 2022-10-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10101708
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Lessons learned from Korea: COVID-19 pandemic.

    Moradi, Hazhir / Vaezi, Atefeh

    Infection control and hospital epidemiology

    2020  Volume 41, Issue 7, Page(s) 873–874

    MeSH term(s) Betacoronavirus ; COVID-19 ; Communication ; Coronavirus Infections/diagnosis ; Coronavirus Infections/prevention & control ; Early Diagnosis ; Humans ; Mass Screening ; Pandemics/prevention & control ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/prevention & control ; Public Health/methods ; Republic of Korea ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-03
    Publishing country United States
    Document type Letter
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2020.104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Infodemic and Risk Communication in the Era of CoV-19.

    Vaezi, Atefeh / Javanmard, Shaghayegh Haghjooy

    Advanced biomedical research

    2020  Volume 9, Page(s) 10

    Keywords covid19
    Language English
    Publishing date 2020-03-11
    Publishing country India
    Document type Editorial
    ZDB-ID 2672524-1
    ISSN 2277-9175
    ISSN 2277-9175
    DOI 10.4103/abr.abr_47_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Blood cell morphology and COVID-19 clinical course, severity, and outcome.

    Pezeshki, Amirhossein / Vaezi, Atefeh / Nematollahi, Pardis

    Journal of hematopathology

    2021  Volume 14, Issue 3, Page(s) 221–228

    Abstract: COVID-19 infection affects different organs of the human body, and blood cells are not an exception. Peripheral blood smear (PBS) is a simple and available method to investigate blood cells' morphologic changes. In this study, we aimed to determine the ... ...

    Abstract COVID-19 infection affects different organs of the human body, and blood cells are not an exception. Peripheral blood smear (PBS) is a simple and available method to investigate blood cells' morphologic changes. In this study, we aimed to determine the morphologic changes and abnormalities of COVID-19 patients and their relation to the patients' clinical course. In this prospective cross-sectional study, we included 89 PCR-positive COVID-19 patients. A pathologist examined the PBS findings of these patients. The patients' clinical course, including severity, outcome, intubation, and ICU admission, was extracted from their profiles. The statistical analyses were done to find out the relation between PBS findings and patients' clinical course. Results showed that smudge cells are the most frequent abnormality in our participants. Other findings were schistocyte; atypical lymphocytes; and increased large granular lymphocytes, shift to left of granulocytes, giant platelets, and leukoerythroblastic reaction. Our results did not show any statistically significant relationship between PBS findings and their clinical course. Although other studies suggested PBS as a possible predictive tool for COVID-19 disease, our study showed that these findings could not predict nor relate to the patients' clinical course.
    Supplementary information: The online version contains supplementary material available at 10.1007/s12308-021-00459-3.
    Language English
    Publishing date 2021-07-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2438687-X
    ISSN 1865-5785 ; 1868-9256
    ISSN (online) 1865-5785
    ISSN 1868-9256
    DOI 10.1007/s12308-021-00459-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Favipiravir in the Treatment of Outpatient COVID-19: A Multicenter, Randomized, Triple-Blind, Placebo-Controlled Clinical Trial.

    Vaezi, Atefeh / Salmasi, Mehrzad / Soltaninejad, Forogh / Salahi, Mehrdad / Javanmard, Shaghayegh Haghjooy / Amra, Babak

    Advances in respiratory medicine

    2023  Volume 91, Issue 1, Page(s) 18–25

    Abstract: Background: Finding effective outpatient treatments to prevent COVID-19 progression and hospitalization is necessary and is helpful in managing limited hospital resources. Repurposing previously existing treatments is highly desirable. In this study, we ...

    Abstract Background: Finding effective outpatient treatments to prevent COVID-19 progression and hospitalization is necessary and is helpful in managing limited hospital resources. Repurposing previously existing treatments is highly desirable. In this study, we evaluate the efficacy of Favipiravir in the prevention of hospitalization in symptomatic COVID-19 patients who were not eligible for hospitalization.
    Methods: This study was a triple-blind randomized controlled trial conducted between 5 December 2020 and 31 March 2021 in three outpatient centers in Isfahan, Iran. Patients in the intervention group received Favipiravir 1600 mg daily for five days, and the control group received a placebo. Our primary outcome was the proportion of hospitalized participants from day 0 to day 28. The outcome was assessed on days 3, 7, 14, 21, and 28 through phone calls.
    Results: Seventy-seven patients were randomly allocated to Favipiravir and placebo groups. There was no significant difference between groups considering baseline characteristics. During the study period, 10.5% of patients in the Favipiravir group and 5.1% of patients in the placebo group were hospitalized, but there was no significant difference between them (
    Conclusions: Our study shows that Favipiravir did not reduce the hospitalization rate of mild to moderate COVID-19 patients in outpatient settings.
    MeSH term(s) Humans ; COVID-19 ; SARS-CoV-2 ; Outpatients ; Amides/adverse effects
    Chemical Substances favipiravir (EW5GL2X7E0) ; Amides
    Language English
    Publishing date 2023-01-28
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Multicenter Study ; Journal Article
    ZDB-ID 2893877-X
    ISSN 2543-6031 ; 2451-4934
    ISSN (online) 2543-6031
    ISSN 2451-4934
    DOI 10.3390/arm91010004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Remdesivir Prescription in Pregnant Women Infected with COVID-19: A Report of Compassionate Use.

    Zafarbakhsh, Azam / Vaezi, Atefeh / Haghjooy Javanmard, Shaghayegh / Sabet, Fahimeh / Dehghan, Maryam

    Advanced biomedical research

    2023  Volume 12, Page(s) 163

    Abstract: Background: Coronavirus disease 2019 (COVID-19) is an infectious disease that the physiological changes in pregnancy can make pregnant patients more susceptible to more severe forms of this infection. Hence, the treatment of COVID-19 in pregnant women ... ...

    Abstract Background: Coronavirus disease 2019 (COVID-19) is an infectious disease that the physiological changes in pregnancy can make pregnant patients more susceptible to more severe forms of this infection. Hence, the treatment of COVID-19 in pregnant women can be challenging. This study was designed to evaluate the safety and efficacy of Remdesivir in pregnant women with COVID-19.
    Materials and methods: This study was conducted on 150 pregnant women with moderate to severe COVID-19 infection. Remdesivir was prescribed and continued for 5 or 10 days according to the patient's condition. Maternal and pregnancy outcomes and also recovery rates were evaluated. Moreover, additional variables were examined: age, gestational age, symptoms, O2 saturation and laboratory tests at admission, the interval between symptom initiation and admission to hospital and Remdesivir prescription, hospitalization days, and ICU admission.
    Results: The mean age was 32.37 years. Cough and dyspnea were the most prevalent symptoms (74% and 68.7%, respectively). At the time of admission, 79 (52.7%) women needed low-flow oxygen support, 67 (44.7%) needed high-flow oxygen support, and 4 (2.7%) were intubated. Fifty-four (36%) patients required ICU care. In patients who died (12 women), Remdesivir was prescribed later than those discharged (
    Conclusion: The results suggest that the early prescription of Remdesivir in pregnant women with moderate COVID-19 can improve the outcomes.
    Language English
    Publishing date 2023-06-30
    Publishing country India
    Document type Journal Article
    ZDB-ID 2672524-1
    ISSN 2277-9175
    ISSN 2277-9175
    DOI 10.4103/abr.abr_142_22
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