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  1. Article: Severe Acute Liver Injury: First Manifestation of Systemic Lupus Erythematosus.

    Singh, Alok K / Vaithiyam, Venkatesh / Sonika, Ujjwal / Goyal, Surbhi

    Journal of clinical and experimental hepatology

    2023  Volume 14, Issue 3, Page(s) 101339

    Abstract: Systemic lupus erythematosus (SLE) is a common multisystem disease characterised by a wide variety of presentation patterns and complex manifestations. As a lymphoid organ, the liver plays an important role in the immune response and is a target of ... ...

    Abstract Systemic lupus erythematosus (SLE) is a common multisystem disease characterised by a wide variety of presentation patterns and complex manifestations. As a lymphoid organ, the liver plays an important role in the immune response and is a target of autoimmune responses.
    Language English
    Publishing date 2023-12-21
    Publishing country India
    Document type Case Reports
    ISSN 0973-6883
    ISSN 0973-6883
    DOI 10.1016/j.jceh.2023.101339
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  2. Article ; Online: Endoscopic ultrasound related partial splenic artery embolization: A gifted outcome.

    Sachdeva, Sanjeev / Vaithiyam, Venkatesh S / Srivastava, Siddharth / Dalal, Ashok

    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology

    2023  Volume 42, Issue 5, Page(s) 734–735

    MeSH term(s) Humans ; Splenic Artery/diagnostic imaging ; Spleen ; Embolization, Therapeutic ; Treatment Outcome
    Language English
    Publishing date 2023-01-25
    Publishing country India
    Document type Journal Article
    ZDB-ID 632595-6
    ISSN 0975-0711 ; 0254-8860
    ISSN (online) 0975-0711
    ISSN 0254-8860
    DOI 10.1007/s12664-022-01301-z
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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Fasting Single Methane Measurement: A Goldmine of Data Worth Exploration.

    Sachdeva, Sanjeev / Vaithiyam, Venkatesh S / Kumar, Ajay / Dalal, Ashok

    The American journal of gastroenterology

    2022  Volume 117, Issue 10, Page(s) 1718

    MeSH term(s) Fasting ; Humans ; Methane
    Chemical Substances Methane (OP0UW79H66)
    Language English
    Publishing date 2022-06-24
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 390122-1
    ISSN 1572-0241 ; 0002-9270
    ISSN (online) 1572-0241
    ISSN 0002-9270
    DOI 10.14309/ajg.0000000000001881
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  4. Article ; Online: Expansile cough impulse: a useful clinical sign for empyema necessitans.

    Banerjee, Sayantan / Biswas, Sagnik / Ray, Animesh / Vaithiyam, Venkatesh

    BMJ case reports

    2019  Volume 12, Issue 3

    MeSH term(s) Adult ; Cough/diagnosis ; Cough/microbiology ; Diagnosis, Differential ; Empyema, Tuberculous/diagnosis ; Empyema, Tuberculous/microbiology ; Humans ; Male ; Mycobacterium tuberculosis ; Thoracic Wall/microbiology
    Language English
    Publishing date 2019-03-31
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2019-229696
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  5. Article ; Online: Risk factors of multidrug-resistant bacterial infections among patients admitted in a tertiary care hospital of north India.

    Vaithiyam, Venkatesh / Ranjan, Piyush / Desai, Devashish / Mittal, Ankit / Kapil, Arti / Wig, Naveet / Biswas, Ashutosh

    Journal of infection in developing countries

    2021  Volume 15, Issue 4, Page(s) 544–551

    Abstract: Introduction: Infections with drug-resistant organisms (DRO) have been associated with poor patient outcomes. To tackle this global problem, it is necessary to understand the risk factors that predispose to infections with DRO.: Methodology: This was ...

    Abstract Introduction: Infections with drug-resistant organisms (DRO) have been associated with poor patient outcomes. To tackle this global problem, it is necessary to understand the risk factors that predispose to infections with DRO.
    Methodology: This was a prospective observational study conducted over a three-year period at a tertiary-care hospital. Bacterial culture isolates from patients admitted in medicine wards with community or hospital-acquired infections were included. Logistic regression analysis was used to determine risk factors for drug-resistant infections.
    Results: Of the 295 patients with 323 isolates included, 40 (12.3%) had non-MDR (N-MDR) infections, 86 (26.6 %) had MDR infections and 197 (61%) had possible extensively drug-resistant (P-XDR) infections. History of previous admission in the preceding three months (Odds Ratio, OR = 4.53, 95% Confidence interval, CI = 1.8 - 11.42, p = -0.01), high SOFA score at admission (OR = 1.14, 95% CI = 1.0 - 1.290, p = -0.039) and prolonged duration of ventilation (OR = 1.25, 95% CI = 1.05 - 1.41, p = -0.012) were independently associated P-XDR infections when compared to patients with N-MDR.
    Conclusions: High rate of multidrug-resistant infections in the studied area is alarming. In this single-centre study, we elicited various risk factors for drug-resistant bacterial infections ranging from patient characteristics to iatrogenic risk factors during the hospital stay. Infections with P-XDR and MDR isolates independently increased hospital and ICU stay duration and were associated with increased mortality.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Community-Acquired Infections/drug therapy ; Community-Acquired Infections/epidemiology ; Community-Acquired Infections/microbiology ; Cross Infection/drug therapy ; Cross Infection/epidemiology ; Cross Infection/microbiology ; Drug Resistance, Multiple, Bacterial/drug effects ; Hospitalization/statistics & numerical data ; Humans ; India/epidemiology ; Prospective Studies ; Risk Factors ; Tertiary Care Centers/statistics & numerical data
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-04-30
    Publishing country Italy
    Document type Journal Article ; Observational Study
    ZDB-ID 2394024-4
    ISSN 1972-2680 ; 2036-6590
    ISSN (online) 1972-2680
    ISSN 2036-6590
    DOI 10.3855/jidc.13963
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  6. Article ; Online: A 23-Year-Old Woman With a Rare Presentation of Systemic Lupus Erythematosus and Its Complication.

    Ch, Rahul / Vaithiyam, Venkatesh Sudharsan / Manchanda, Smita / Barman Roy, Debarchan / Kumar, Sanchit / Ray, Animesh / Vikram, Naval

    Chest

    2021  Volume 160, Issue 6, Page(s) e661–e664

    MeSH term(s) Diagnosis, Differential ; Enteritis/diagnostic imaging ; Enteritis/etiology ; Enteritis/surgery ; Enterocolitis, Necrotizing/diagnostic imaging ; Enterocolitis, Necrotizing/etiology ; Enterocolitis, Necrotizing/surgery ; Female ; Humans ; Lupus Erythematosus, Systemic/complications ; Ultrasonography/methods ; Young Adult
    Language English
    Publishing date 2021-12-07
    Publishing country United States
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2021.02.079
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    Zs.MO 349: Show issues

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  7. Article: Enhanced Liver Fibrosis Score: Is It Useful for Evaluation of Fibrosis Severity in Chronic Hepatitis C Infection?

    Kumar, Manish / George, Roshan / Vaithiyam, Venkatesh / Sakhuja, Puja / Dahale, Amol S / Dayal, Aman / Dalal, Ashok / Sonika, Ujjwal / Sachdeva, Sanjeev / Kumar, Ajay

    Cureus

    2022  Volume 14, Issue 1, Page(s) e21168

    Abstract: Introduction: The assessment of liver fibrosis is important in patients with chronic hepatitis C (CHC). In recent years, non-invasive tests like enhanced liver fibrosis (ELF) have been developed as an alternative to liver biopsy for estimating the ... ...

    Abstract Introduction: The assessment of liver fibrosis is important in patients with chronic hepatitis C (CHC). In recent years, non-invasive tests like enhanced liver fibrosis (ELF) have been developed as an alternative to liver biopsy for estimating the severity of liver fibrosis. Therefore, we aimed to assess whether the ELF score can be used for fibrosis severity estimation using liver biopsy as the gold standard.
    Materials and methods: Forty-nine patients with CHC were enrolled in this study. Liver biopsy, ELF assessment, and transient elastography (TE) were performed in all patients, and severity of fibrosis on histopathology was assessed by meta-analysis of histological data in viral hepatitis (METAVIR) score. In addition, the diagnostic performance of ELF was evaluated by receiver operator characteristic curve (ROC) analyses, and liver biopsy histopathology was taken as the gold standard for the severity of liver fibrosis.
    Results: The area under receiver operator characteristic curve (AUROC) for significant fibrosis of ELF score was 0.64 (95% confidence interval {CI}, 0.48-0.79) and of TE was 0.85 (95% CI, 0.73-0.96). The AUROC for advance fibrosis of ELF was 0.77 (95% CI, 0.57-0.97) and TE was 0.98 (95% CI, 0.94-1.0). The calculated cut-offs of ELF overestimated fibrosis in 53.06% (26/49) of patients and underestimated fibrosis in 6.12% (3/49) patients. AUROC of TE was significantly better than ELF for diagnosis of significant fibrosis (p=0.004) and advanced fibrosis (p=0.034).
    Conclusion: The ELF score can be used for estimating the severity of fibrosis but it is inferior to TE in estimating liver fibrosis severity.
    Language English
    Publishing date 2022-01-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.21168
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  8. Article: Antimicrobial Resistance Patterns in Clinically Significant Isolates from Medical Wards of a Tertiary Care Hospital in North India.

    Vaithiyam, Venkatesh Sudharsan / Rastogi, Neha / Ranjan, Piyush / Mahishi, Niranjan / Kapil, Arti / Dwivedi, Sada Nand / Soneja, Manish / Wig, Naveet / Biswas, Ashutosh

    Journal of laboratory physicians

    2020  Volume 12, Issue 3, Page(s) 196–202

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2020-11-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2461120-7
    ISSN 0974-7826 ; 0974-2727
    ISSN (online) 0974-7826
    ISSN 0974-2727
    DOI 10.1055/s-0040-1721161
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  9. Article: Metronidazole induced encephalopathy: A rare side effect with a common drug.

    Vaithiyam, Venkatesh / Jadon, Ranveer S / Ray, Animesh / Manchanda, Smita / Meena, Ved P / Ranjan, Piyush / Vikram, Naval K

    The Indian journal of radiology & imaging

    2019  Volume 29, Issue 4, Page(s) 431–434

    Abstract: In hospitals, seizures and encephalopathy are one of the common complications observed in critically ill patients. Drug intoxication, metabolic derangements, and anatomical abnormalities can cause altered mental status. We encountered an uncommon case ... ...

    Abstract In hospitals, seizures and encephalopathy are one of the common complications observed in critically ill patients. Drug intoxication, metabolic derangements, and anatomical abnormalities can cause altered mental status. We encountered an uncommon case with a diagnostic dilemma due to persistent encephalopathy, where metronidazole toxicity was an etiological factor. A 45-year-old male, who was admitted with the diagnosis of ruptured amoebic liver abscess. During the course of his management, he developed seizures and altered sensorium. After excluding other etiologies for in-hospital de novo seizure, a suspicion of metronidazole toxicity was considered. MRI brain was done which suggested the same. Metronidazole induced encephalopathy (MIE) is an uncommon adverse effect of treatment with metronidazole. Diagnosis is made by identifying specific radiological findings. It characteristically affects the cerebellum and subcortical structures. While the clinical and neuroimaging changes are usually reversible, persistent encephalopathy with poor outcomes may occur as seen in our case.
    Language English
    Publishing date 2019-12-31
    Publishing country India
    Document type Case Reports
    ZDB-ID 605869-3
    ISSN 0971-3026 ; 0970-2016
    ISSN 0971-3026 ; 0970-2016
    DOI 10.4103/ijri.IJRI_330_19
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  10. Article: Antimicrobial Resistance Patterns in Clinically Significant Isolates from Medical Wards of a Tertiary Care Hospital in North India

    Vaithiyam, Venkatesh Sudharsan / Rastogi, Neha / Ranjan, Piyush / Mahishi, Niranjan / Kapil, Arti / Dwivedi, Sada Nand / Soneja, Manish / Wig, Naveet / Biswas, Ashutosh

    Journal of Laboratory Physicians

    2020  Volume 12, Issue 03, Page(s) 196–202

    Abstract: Background: The global burden of infections due to multidrug-resistant organism (MDRO) has a significant impact on patients’ morbidity and mortality along with increased healthcare expenditure.: Aim: This article estimates the prevalence of MDRO and ... ...

    Abstract Background: The global burden of infections due to multidrug-resistant organism (MDRO) has a significant impact on patients’ morbidity and mortality along with increased healthcare expenditure.
    Aim: This article estimates the prevalence of MDRO and the spectrum of clinical infectious syndromes caused by these organisms in medical wards of a tertiary care hospital in India.
    Design and Methods: A cross-sectional observational study was performed among patients admitted in medicine wards diagnosed with the various infectious syndromes and one or more clinically significant positive culture at a tertiary care hospital in North India over a period of 18 months.
    Results: Out of 323 clinically significant microbiological culture isolates from 229 patients included in the study, 86 (27%) isolates showed multidrug resistance (MDR) pattern, 197 (61%) isolates showed possible extremely drug-resistance pattern, and only 40 (12%) isolates showed nonmultidrug-resistance pattern of antibiogram.
    Conclusion: The prevalence of MRDOs is high in clinically significant culture isolates from medicine wards in India. This emphasizes the importance of appropriate antibiotic usage and implementation of antibiotic stewardship programs in this part of the world.
    Keywords drug-resistant infections ; antimicrobial resistance, antibiogram
    Language English
    Publishing date 2020-11-23
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2461120-7
    ISSN 0974-7826 ; 0974-2727 ; 0974-7826
    ISSN (online) 0974-7826
    ISSN 0974-2727 ; 0974-7826
    DOI 10.1055/s-0040-1721161
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