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  1. Article ; Online: Burnout Syndrome among Otorhinolaryngologists during the COVID-19 Pandemic.

    Šiupšinskienė, Nora / Spiridonovienė, Brigita / Pašvenskaitė, Agnė / Vaitkus, Justinas / Vaitkus, Saulius

    Medicina (Kaunas, Lithuania)

    2022  Volume 58, Issue 8

    Abstract: Background and Objectives: To determine the prevalence of burnout syndrome among otorhinolaryngologists in Lithuania and investigate associations with sociodemographic and professional factors during the COVID-19 pandemic. Materials and Methods: Burnout ... ...

    Abstract Background and Objectives: To determine the prevalence of burnout syndrome among otorhinolaryngologists in Lithuania and investigate associations with sociodemographic and professional factors during the COVID-19 pandemic. Materials and Methods: Burnout was measured using the validated Lithuanian version of the Maslach Burnout Inventory. Demographic characteristics and professional characteristics were collected utilizing an anonymous questionnaire. Results: Eighty otorhinolaryngologists (ORL group) and 30 information technology professionals (the control group) were enrolled in this study. A high level of professional burnout in at least one of the subscales was observed in 82.5% of the ORL group subjects. Depersonalization and burnout syndrome were more frequently detected with increasing age in the ORL group (r = 0.2, p < 0.04). Greater satisfaction with salary and working environment resulted in a lower burnout incidence (r = 0.31, p = 0.001). Conclusions: During the COVID-19 pandemic, the incidence of burnout syndrome has been high among Lithuanian otorhinolaryngologists. Demographic and professional characteristics are significantly related to burnout syndrome among Lithuanian otorhinolaryngologists.
    MeSH term(s) Burnout, Professional/epidemiology ; COVID-19/epidemiology ; Humans ; Pandemics ; Surveys and Questionnaires ; Workplace
    Language English
    Publishing date 2022-08-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina58081089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Chronic Rhinosinusitis with Nasal Polyps: Age and Disease Severity Differences in the Levels of Inflammatory Markers.

    Vaitkus, Justinas / Vitkauskienė, Astra / Simuntis, Regimantas / Vaitkus, Žygimantas / Šiupšinskienė, Nora / Vaitkus, Saulius

    Medicina (Kaunas, Lithuania)

    2021  Volume 57, Issue 3

    Abstract: Background and objectives: ...

    Abstract Background and objectives:
    MeSH term(s) Adolescent ; Adult ; Chronic Disease ; Humans ; Middle Aged ; Nasal Polyps/complications ; Paranasal Sinuses ; Rhinitis ; Severity of Illness Index ; Sinusitis ; Young Adult
    Language English
    Publishing date 2021-03-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina57030282
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Chronic Odontogenic Rhinosinusitis: Optimization of Surgical Treatment Indications.

    Simuntis, Regimantas / Kubilius, Ričardas / Tušas, Paulius / Leketas, Marijus / Vaitkus, Justinas / Vaitkus, Saulius

    American journal of rhinology & allergy

    2020  Volume 34, Issue 6, Page(s) 767–774

    Abstract: Background: The treatment of chronic odontogenic and nonodontogenic rhinosinusitis is different. It requires the elimination of odontogenic cause and optimal sinus surgical treatment. To date, there are no clear indications when sinus surgical treatment ...

    Abstract Background: The treatment of chronic odontogenic and nonodontogenic rhinosinusitis is different. It requires the elimination of odontogenic cause and optimal sinus surgical treatment. To date, there are no clear indications when sinus surgical treatment is necessary.
    Objective: Our aim was to define clear indication(s) for sinus surgical treatment in patients with chronic odontogenic rhinosinusitis after elimination of odontogenic cause.
    Methods: A group of 96 patients with chronic odontogenic rhinosinusitis caused by apical periodontitis completed a Sino-Nasal Outcome Test 22 (SNOT-22) questionnaire with incorporated additional symptom "malodor" before treatment. Moreover, they were distributed according to computed tomography (CT) radiological criteria such as degree of periapical pathology, anatomical ratio between maxillary lateral teeth and sinus floor, sinus mucosal thickening, and ostiomeatal complex condition. The elimination of odontogenic cause was performed by extracting causative tooth. Questionnaire was filled again 2 weeks, 3 months, and 6 months after treatment. All data were analyzed to search the clear indications for sinus surgical treatment.
    Results: Of 96 patients, 74 (77.1%) patients had full resolution of symptoms after dental cause was eliminated. For other 22 (22.9%) patients, symptoms persisted and sinus surgical treatment was indicated. In recovered group, mean SNOT-22 score was different between all periods of measuring, while within nonrecovered group, small differences were seen only when compared to before treatment. No statistically significant correlation between radiological criteria and rhinosinusitis healing after tooth extraction was found (
    Conclusions: Our study revealed that extraction of causative tooth is an effective treatment of chronic odontogenic rhinosinusitis caused by apical periodontitis. CT criteria are not valuable indicator for sinus surgery, but persistence of malodor after 2 weeks is the strongest indication for this type of treatment.
    MeSH term(s) Chronic Disease ; Endoscopy ; Humans ; Paranasal Sinuses ; Rhinitis/surgery ; Sinus Floor Augmentation ; Sinusitis/surgery
    Language English
    Publishing date 2020-05-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2482804-X
    ISSN 1945-8932 ; 1945-8924
    ISSN (online) 1945-8932
    ISSN 1945-8924
    DOI 10.1177/1945892420929265
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Local inflammatory marker production in Lithuanian patients with chronic rhinosinusitis with nasal polyps.

    Vaitkus, Justinas / Vitkauskiene, Astra / Matuseviciute, Vilte / Naudziunas, Albinas / Siupsinskiene, Nora / Vaitkus, Saulius

    Journal of immunotoxicology

    2020  Volume 17, Issue 1, Page(s) 202–206

    Abstract: There are two clinical subtypes of chronic rhinosinusitis (CRS): chronic rhinosinusitis with nasal polyps (CRSwNP) and chronic rhinosinusitis without nasal polyps (CRSsNP). The aim of the study here was to determine the levels of invasive inflammatory ... ...

    Abstract There are two clinical subtypes of chronic rhinosinusitis (CRS): chronic rhinosinusitis with nasal polyps (CRSwNP) and chronic rhinosinusitis without nasal polyps (CRSsNP). The aim of the study here was to determine the levels of invasive inflammatory markers in nasal mucosa samples taken from CRSwNP patients during the surgery and to identify markers that could serve as targets for potential clinical and therapeutic interventions. The study was carried out in 59 patients with proven CRSwNP and a control group consisting of 52 healthy individuals. Concentrations of the inflammatory markers of interest were determined using a LuminexR Assay multiplex kit. The data obtained indicated that levels of inflammatory cytokines interleukin (IL)-2, -4, -5, -7, -12, -17 and -22 were all significantly higher in the nasal polyps (NP) than those in the mucosa of control participants. No differences were seen between the study groups for IL -6, -10, -13, -21 and interferon (IFN)-γ. OR (Odds Ratio) analyses confirmed that elevations in mucosal levels of IL-2, -4, -5, -7, -12, -17, and -22 were likely immune markers of CRSwNP. In conclusion, the present study demonstrated that IL-2, -4, -12 and -22 may be important in the etiopathogenesis of CRSwNP; as markers, each show moderate sensitivity, but high specificity in the Lithuanian population. IL-17 had good sensitivity, but low specificity in the CRSwNP patients.
    MeSH term(s) Adult ; Biomarkers/metabolism ; Chronic Disease ; Female ; Humans ; Inflammation Mediators/metabolism ; Lithuania/epidemiology ; Male ; Middle Aged ; Nasal Mucosa/metabolism ; Nasal Polyps ; Rhinitis/diagnosis ; Rhinitis/epidemiology ; Sensitivity and Specificity ; Sinusitis/diagnosis ; Sinusitis/epidemiology
    Chemical Substances Biomarkers ; Inflammation Mediators
    Language English
    Publishing date 2020-12-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2205064-4
    ISSN 1547-6901 ; 1547-691X
    ISSN (online) 1547-6901
    ISSN 1547-691X
    DOI 10.1080/1547691X.2020.1850938
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Dislocation density-dependent photorefractive effect in (001)-cut GaAs.

    Jarasiunas, K / Vaitkus, J / Delaye, P / Roosen, G

    Optics letters

    2008  Volume 19, Issue 23, Page(s) 1946–1948

    Abstract: We present studies of the photorefractive effect in nonphotorefractive orientations of liquid-encapsulated Czochralski-grown GaAs crystals. Picosecond diffraction experiments conducted in different samples show that a forbidden photorefractive signal ... ...

    Abstract We present studies of the photorefractive effect in nonphotorefractive orientations of liquid-encapsulated Czochralski-grown GaAs crystals. Picosecond diffraction experiments conducted in different samples show that a forbidden photorefractive signal correlates well with dislocation density, which points out that the effect arises from strain fields and growth defects.
    Language English
    Publishing date 2008-09-11
    Publishing country United States
    Document type Journal Article
    ISSN 0146-9592
    ISSN 0146-9592
    DOI 10.1364/ol.19.001946
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Instrumentation for the in situ control of carrier recombination characteristics during irradiation by protons.

    Gaubas, E / Uleckas, A / Vaitkus, J / Raisanen, J / Tikkanen, P

    The Review of scientific instruments

    2010  Volume 81, Issue 5, Page(s) 53303

    Abstract: Instrument and methods for the remote and in situ control of carrier recombination parameters during irradiation by protons of energy in the range of 3-8 MeV are presented. Direct techniques for measurements and separation of carrier recombination and ... ...

    Abstract Instrument and methods for the remote and in situ control of carrier recombination parameters during irradiation by protons of energy in the range of 3-8 MeV are presented. Direct techniques for measurements and separation of carrier recombination and trapping/generation characteristics based on the analysis of microwave probed photoconductivity transients during exposure on protons of different energies and irradiations at different temperatures are described. Simultaneously, a spectroscopy of activation energy of dominant traps has been performed before and just after irradiation by temperature scans of variation in the recombination parameters.
    Language English
    Publishing date 2010-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209865-9
    ISSN 1089-7623 ; 0034-6748
    ISSN (online) 1089-7623
    ISSN 0034-6748
    DOI 10.1063/1.3429944
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Comparison of Sino-Nasal Outcome Test 22 Symptom Scores in Rhinogenic and Odontogenic Sinusitis.

    Simuntis, Regimantas / Vaitkus, Justinas / Kubilius, Ričardas / Padervinskis, Evaldas / Tušas, Paulius / Leketas, Marijus / Šiupšinskienė, Nora / Vaitkus, Saulius

    American journal of rhinology & allergy

    2018  Volume 33, Issue 1, Page(s) 44–50

    Abstract: Background: Odontogenic maxillary sinusitis (OMS) and rhinogenic sinusitis (RS) are the main types of chronic rhinosinusitis (CRS) and have a significant impact on health-related quality of life (HRQL), but the difference in HRQL and symptom ... ...

    Abstract Background: Odontogenic maxillary sinusitis (OMS) and rhinogenic sinusitis (RS) are the main types of chronic rhinosinusitis (CRS) and have a significant impact on health-related quality of life (HRQL), but the difference in HRQL and symptom presentation between them has not been specifically evaluated to date. Obejctive: Our aim was to compare patterns of symptoms and HRQL disease-specific domains in patients affected with these 2 types of CRS.
    Methods: A group of 201 patients with CRS (99 with rhinogenic and 102 with odontogenic origin) completed the Sino-Nasal Outcome Test 22 (SNOT-22) questionnaire before treatment. Data sets were analyzed by using principal component analysis (PCA) to identify a set of symptom components together with the items excluded from PCA, which were then analyzed for differences between patients with OMS and RS.
    Results: PCA of SNOT-22 items identified 5 components: "rhinologic," "extranasal rhinologic," "ear/facial," "sleep and functional disturbance," and "emotional disturbance." Sneezing was excluded from PCA and treated as separate outcome variable and was significantly worse in RS patients. Patients with OMS scored significantly higher scores with regard to emotional disturbance, while RS patients scored significantly worse in sleep and functional disturbance. The extra symptom "malodor" was the most different symptom and was significantly worse in OMS patients. The total SNOT-22 score was not significantly different between the groups.
    Conclusion: With controlling of covariates that may influence the severity of the disease, this study showed some significant differences in symptom patterns and HRQL impairment between patients with OMS and RS. Malodor is the most characteristic feature of OMS. Therefore, OMS should always be suspected in patients complaining of bad breath.
    MeSH term(s) Adult ; Chronic Disease ; Female ; Humans ; Male ; Middle Aged ; Odorants ; Paranasal Sinuses/pathology ; Principal Component Analysis ; Prospective Studies ; Quality of Life ; Rhinitis/diagnosis ; Rhinitis/physiopathology ; Sinusitis/diagnosis ; Sinusitis/physiopathology ; Surveys and Questionnaires ; Tooth/pathology
    Language English
    Publishing date 2018-10-12
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Observational Study
    ZDB-ID 2482804-X
    ISSN 1945-8932 ; 1945-8924
    ISSN (online) 1945-8932
    ISSN 1945-8924
    DOI 10.1177/1945892418804975
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online: The effect of atomic structure on the electrical response of aluminium oxide tunnel junctions

    Cyster, M. J. / Smith, J. S. / Vaitkus, J. A. / Vogt, N. / Russo, S. P. / Cole, J. H.

    2019  

    Abstract: Many nanoelectronic devices rely on thin dielectric barriers through which electrons tunnel. For instance, aluminium oxide barriers are used as Josephson junctions in superconducting electronics. The reproducibility and drift of circuit parameters in ... ...

    Abstract Many nanoelectronic devices rely on thin dielectric barriers through which electrons tunnel. For instance, aluminium oxide barriers are used as Josephson junctions in superconducting electronics. The reproducibility and drift of circuit parameters in these junctions are affected by the uniformity, morphology, and composition of the oxide barriers. To improve these circuits the effect of the atomic structure on the electrical response of aluminium oxide barriers must be understood. We create three-dimensional atomistic models of aluminium oxide tunnel junctions and simulate their electronic transport properties with the non-equilibrium Green's function formalism. Increasing the oxide density is found to produce an exponential increase in the junction resistance. In highly oxygen-deficient junctions we observe metallic channels which decrease the resistance significantly. Computing the charge and current density within the junction shows how variation in the local potential landscape can create channels which dominate conduction. An atomistic approach provides a better understanding of these transport processes and guides the design of junctions for nanoelectronics applications.

    Comment: 10 pages, 9 figures
    Keywords Condensed Matter - Mesoscale and Nanoscale Physics ; Condensed Matter - Materials Science ; Condensed Matter - Superconductivity ; Quantum Physics
    Subject code 669
    Publishing date 2019-05-29
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Translation, cross-cultural adaptation, and validation of the sino-nasal outcome test (SNOT)-22 for Lithuanian patients.

    Vaitkus, Saulius / Padervinskis, Evaldas / Balsevicius, Tomas / Siupsinskiene, Nora / Staikuniene, Jurate / Ryskiene, Silvija / Lisauskaite, Laura / Vaitkus, Justinas

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2012  Volume 270, Issue 6, Page(s) 1843–1848

    Abstract: The objective of this study was to perform translation, cross-cultural adaptation, and validation of the SNOT-22 in the Lithuanian language. This is a prospective case-control study. The study was conducted at the University clinic. The sino-nasal ... ...

    Abstract The objective of this study was to perform translation, cross-cultural adaptation, and validation of the SNOT-22 in the Lithuanian language. This is a prospective case-control study. The study was conducted at the University clinic. The sino-nasal outcome test 22 (SNOT-22) was translated into the Lithuanian language; the pilot study involved 34 patients, the test-retest group consisted of 34 patients with chronic rhinosinusitis (CRS), and the control group of 115 patients with no CRS complaints; 36 patients were evaluated before surgery and 3 months after surgery. The results showed a good internal correlation with Cronbach's alpha-0.89 in the initial test, and 0.93 in the retest; both values suggesting good internal consistency within the SNOT-22. Pearson's correlation coefficient was 0.72 (p < 0.001), revealing good correlation between the initial scores and the retests scores. Our sample of healthy individuals had a median score of 12 points, and the instrument was capable of differentiating between the healthy and the patient group, demonstrating its validity (p < 0.0001). The statistically significant reduction in the post-operative scores, vis-à-vis pre-operative values, demonstrates the responsiveness of the instrument. The minimally important difference was 13 points in the SNOT-22 score. The Lithuanian version of the SNOT-22 is a valid instrument for assessing patients with CRS. It demonstrated good internal consistency, reproducibility, validity, and responsiveness.
    MeSH term(s) Adult ; Aged ; Chronic Disease ; Cross-Cultural Comparison ; Female ; Humans ; Lithuania ; Male ; Middle Aged ; Outcome Assessment, Health Care/methods ; Pilot Projects ; Quality of Life ; Sinusitis/complications ; Sinusitis/surgery ; Surveys and Questionnaires ; Translations
    Language English
    Publishing date 2012-12-01
    Publishing country Germany
    Document type Journal Article ; Validation Study
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-012-2282-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Kai kuriu fasciolocidiniu preparatu itaka karviu pieno kokybei

    Vaitkus, J / Vysniauskas, A / Rudaitis, A

    Darbai - Lietuvos veterinarijos akademijos. 1980. v. 13

    1980  

    Title translation Study of the influence of some fasciolicidal preparations on cow milk quality.
    Title variant Study of the influence of some fasciolicidal preparations on cow milk quality [Contamination]
    Keywords food contamination ; dairy products
    Language Lithuanian
    Size p. 173-182., ill.
    Document type Article
    Note Summary in Russian.
    Database NAL-Catalogue (AGRICOLA)

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