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  1. AU="Valdés-Hernández, Jesús"
  2. AU="Wong, Wei Yin"
  3. AU="Konstantinos Koutroumpas"
  4. AU="Kumar Thulasi"
  5. AU="Elbe, Peter"
  6. AU=Ryffel Gerhart U
  7. AU="López Panadés, Maria"
  8. AU="Tormo, Hélène"
  9. AU="Gardham, Alice"
  10. AU="Chisa Inoue"
  11. AU=Savcenko Michal AU=Savcenko Michal
  12. AU=Dinda Biswanath AU=Dinda Biswanath
  13. AU="Heikinheimo Annamari"
  14. AU="Currie, Geoffrey"
  15. AU="Konno, Adriana Y C"
  16. AU="Nashmi, Raad"
  17. AU="Doligkeit, Daniel"
  18. AU="Caparello, Basilio"
  19. AU="Fricke, T T"
  20. AU="Mummery, C J"
  21. AU="Krantz, Emily"
  22. AU="Bedoya-Arias, Juan E"
  23. AU="Zhou, Heyang"
  24. AU=Latson Larry A
  25. AU=Alhuzimi Eman
  26. AU="Wuerzberger-Davis, Shelly M"
  27. AU="Clippinger, Amy J"
  28. AU="M. S. Islam"
  29. AU="Borrego-Jiménez, Jaime"
  30. AU="Kaoru Dohi"
  31. AU="Tornai, Gábor J"
  32. AU="D'Avella, Christopher"
  33. AU="Lim, Boon L."
  34. AU="Heselden, Marie"
  35. AU=Dias?Polak David
  36. AU="Shahid Umar"
  37. AU="Abu-Shmais, Alexandria A"
  38. AU="Takenaka, Haruka"
  39. AU="Bramley, Andrea"
  40. AU="Sang Hong Lee"

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  1. Artikel ; Online: Recipient maternal genotypes improved the litter size components of a paternal line involved in a MOET programme in rabbits

    Rajab, Muḥammad / Valdés-Hernández, Jesús / Vicente, José S. / Marco-Jiménez, Francisco

    Italian Journal of Animal Science. 2022 Dec. 31, v. 21, no. 1 p.1584-1592

    2022  

    Abstract: An essential factor in the success of multiple ovulation and embryo transfer programmes (MOET) in any species is the selection of the recipient females. In rabbit there is a notable lack of studies on the effects of recipient genotype on postnatal growth. ...

    Abstract An essential factor in the success of multiple ovulation and embryo transfer programmes (MOET) in any species is the selection of the recipient females. In rabbit there is a notable lack of studies on the effects of recipient genotype on postnatal growth. The aim of this study was to evaluate the effects of recipient maternal genotypes on litter size components within a MOET programme applied to a commercial paternal line that appears to have exhausted its selection programme after 37 generations. The experiment was designed using 13 nulliparous donors from the R line (paternal line) to produce 453 embryos, which were transferred to two recipient maternal genotypes (A and V lines) and the own donor paternal line (R line). Litter size components and pre-and postnatal body mass of kits were evaluated. The differences between the genetic groups of recipients were estimated using a general linear model applying Bayesian analysis. The results showed that maternal lines have a high capacity to implant the embryos, maintain the pregnancy and present a favourable environment for embryo development compared to the R line. Specifically, A line dams showed the highest prenatal survival, total born and number born alive without effects on growth traits. The present study demonstrated the applicability of a MOET programme based on maternal ability recipients to improve the number of kits per cycle. Therefore, to allow the genetic improvement programme of meat rabbits to continue using the R line, we recommended applying for a MOET programme as a routine procedure.HIGHLIGHTSMOET programme based on maternal ability recipients enhanced the number of kits per cycle. The MOET programme could be a routine procedure to favour the selection of paternal lines by increasing selection pressure.
    Schlagwörter Bayesian theory ; animal science ; body weight ; embryo transfer ; embryogenesis ; genetic improvement ; genotype ; linear models ; litter size ; meat ; ovulation ; pregnancy ; rabbits ; selection pressure ; Superovulation ; embryos ; donor ; recipient ; breeding ; growth traits
    Sprache Englisch
    Erscheinungsverlauf 2022-1231
    Umfang p. 1584-1592.
    Erscheinungsort Taylor & Francis
    Dokumenttyp Artikel ; Online
    ZDB-ID 2408994-1
    ISSN 1828-051X
    ISSN 1828-051X
    DOI 10.1080/1828051X.2022.2142167
    Datenquelle NAL Katalog (AGRICOLA)

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  2. Artikel ; Online: Correction: Identification of candidate regulatory genes for intramuscular fatty acid composition in pigs by transcriptome analysis.

    Valdés-Hernández, Jesús / Folch, Josep M / Crespo-Piazuelo, Daniel / Passols, Magí / Sebastià, Cristina / Criado-Mesas, Lourdes / Castelló, Anna / Sánchez, Armand / Ramayo-Caldas, Yuliaxis

    Genetics, selection, evolution : GSE

    2024  Band 56, Heft 1, Seite(n) 14

    Sprache Englisch
    Erscheinungsdatum 2024-02-26
    Erscheinungsland France
    Dokumenttyp Published Erratum
    ZDB-ID 1005838-2
    ISSN 1297-9686 ; 0754-0264 ; 0999-193X
    ISSN (online) 1297-9686
    ISSN 0754-0264 ; 0999-193X
    DOI 10.1186/s12711-024-00885-8
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Identification of candidate regulatory genes for intramuscular fatty acid composition in pigs by transcriptome analysis.

    Valdés-Hernández, Jesús / Folch, Josep M / Crespo-Piazuelo, Daniel / Passols, Magí / Sebastià, Cristina / Criado-Mesas, Lourdes / Castelló, Anna / Sánchez, Armand / Ramayo-Caldas, Yuliaxis

    Genetics, selection, evolution : GSE

    2024  Band 56, Heft 1, Seite(n) 12

    Abstract: Background: Intramuscular fat (IMF) content and its fatty acid (FA) composition are typically controlled by several genes, each with a small effect. In the current study, to pinpoint candidate genes and putative regulators involved in FA composition, we ...

    Abstract Background: Intramuscular fat (IMF) content and its fatty acid (FA) composition are typically controlled by several genes, each with a small effect. In the current study, to pinpoint candidate genes and putative regulators involved in FA composition, we performed a multivariate integrative analysis between intramuscular FA and transcriptome profiles of porcine longissimus dorsi (LD) muscle. We also carried out a combination of network, regulatory impact factor (RIF), in silico prediction of putative target genes, and functional analyses to better support the biological relevance of our findings.
    Results: For this purpose, we used LD RNA-Seq and intramuscular FA composition profiles of 129 Iberian × Duroc backcrossed pigs. We identified 378 correlated variables (13 FA and 365 genes), including six FA (C20:4n-6, C18:2n-6, C20:3n-6, C18:1n-9, C18:0, and C16:1n-7) that were among the most interconnected variables in the predicted network. The detected FA-correlated genes include genes involved in lipid and/or carbohydrate metabolism or in regulation of IMF deposition (e.g., ADIPOQ, CHUK, CYCS, CYP4B1, DLD, ELOVL6, FBP1, G0S2, GCLC, HMGCR, IDH3A, LEP, LGALS12, LPIN1, PLIN1, PNPLA8, PPP1R1B, SDR16C5, SFRP5, SOD3, SNW1, and TFRC), meat quality (GALNT15, GOT1, MDH1, NEU3, PDHA1, SDHD, and UNC93A), and transport (e.g., EXOC7 and SLC44A2). Functional analysis highlighted 54 over-represented gene ontology terms, including well-known biological processes and pathways that regulate lipid and carbohydrate metabolism. RIF analysis suggested a pivotal role for six transcription factors (CARHSP1, LBX1, MAFA, PAX7, SIX5, and TADA2A) as putative regulators of gene expression and intramuscular FA composition. Based on in silico prediction, we identified putative target genes for these six regulators. Among these, TADA2A and CARHSP1 had extreme RIF scores and present novel regulators in pigs. In addition, the expression of TADA2A correlated (either positively or negatively) with C20:4n-6, C18:2n-6, C20:3n-6, C18:1n-9, and that of CARHSP1 correlated (positively) with the C16:1n-7 lipokine. We also found that these two transcription factors share target genes that are involved in lipid metabolism (e.g., GOT1, PLIN1, and TFRC).
    Conclusions: This integrative analysis of muscle transcriptome and intramuscular FA profile revealed valuable information about key candidate genes and potential regulators for FA and lipid metabolism in pigs, among which some transcription factors are proposed to control gene expression and modulate FA composition differences.
    Mesh-Begriff(e) Swine/genetics ; Animals ; Fatty Acids/metabolism ; Muscle, Skeletal/metabolism ; Gene Expression Profiling ; Transcription Factors/metabolism ; Genes, Regulator ; Transcriptome
    Chemische Substanzen Fatty Acids ; Transcription Factors
    Sprache Englisch
    Erscheinungsdatum 2024-02-12
    Erscheinungsland France
    Dokumenttyp Journal Article
    ZDB-ID 1005838-2
    ISSN 1297-9686 ; 0754-0264 ; 0999-193X
    ISSN (online) 1297-9686
    ISSN 0754-0264 ; 0999-193X
    DOI 10.1186/s12711-024-00882-x
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  4. Artikel: Proteomic Insights into Seminal Plasma and Spermatozoa Proteins of Small-Spotted Catsharks,

    Muñoz-Baquero, Marta / Lorenzo-Rebenaque, Laura / García-Domínguez, Ximo / Valdés-Hernández, Jesús / García-Párraga, Daniel / Marin, Clara / García-Vázquez, Francisco Alberto / Marco-Jiménez, Francisco

    Animals : an open access journal from MDPI

    2024  Band 14, Heft 9

    Abstract: In the ex situ conservation of chondrichthyan species, successful reproduction in aquaria is essential. However, these species often exhibit reduced reproductive success under human care. A key aspect is that conventional sperm analyses do not provide ... ...

    Abstract In the ex situ conservation of chondrichthyan species, successful reproduction in aquaria is essential. However, these species often exhibit reduced reproductive success under human care. A key aspect is that conventional sperm analyses do not provide insights into the functional competence of sperm. However, proteomics analysis enables a better understanding of male physiology, gaining relevance as a powerful tool for discovering protein biomarkers related to fertility. The present work aims to build the first proteome database for shark semen and to investigate the proteomic profiles of seminal plasma and spermatozoa from small-spotted catsharks (
    Sprache Englisch
    Erscheinungsdatum 2024-04-24
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14091281
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Global analysis of the association between pig muscle fatty acid composition and gene expression using RNA-Seq.

    Valdés-Hernández, Jesús / Ramayo-Caldas, Yuliaxis / Passols, Magí / Sebastià, Cristina / Criado-Mesas, Lourdes / Crespo-Piazuelo, Daniel / Esteve-Codina, Anna / Castelló, Anna / Sánchez, Armand / Folch, Josep M

    Scientific reports

    2023  Band 13, Heft 1, Seite(n) 535

    Abstract: Fatty acids (FAs) play an essential role as mediators of cell signaling and signal transduction, affecting metabolic homeostasis and determining meat quality in pigs. However, FAs are transformed by the action of several genes, such as those encoding ... ...

    Abstract Fatty acids (FAs) play an essential role as mediators of cell signaling and signal transduction, affecting metabolic homeostasis and determining meat quality in pigs. However, FAs are transformed by the action of several genes, such as those encoding desaturases and elongases of FAs in lipogenic tissues. The aim of the current work was to identify candidate genes, biological processes, and pathways involved in the modulation of intramuscular FA profile from longissimus dorsi muscle. FA profile by gas chromatography of methyl esters and gene expression by RNA-Seq were determined in 129 Iberian × Duroc backcrossed pigs. An association analysis between the muscle transcriptome and its FA profile was performed, followed by a concordance and functional analysis. Overall, a list of well-known (e.g., PLIN1, LEP, ELOVL6, SC5D, NCOA2, ACSL1, MDH1, LPL, LGALS12, TFRC, GOT1, and FBP1) and novel (e.g., TRARG1, TANK, ENSSSCG00000011196, and ENSSSCG00000038429) candidate genes was identified, either in association with specific or several FA traits. Likewise, several of these genes belong to biological processes and pathways linked to energy, lipid, and carbohydrate metabolism, which seem determinants in the modulation of FA compositions. This study can contribute to elucidate the complex relationship between gene expression and FA profile in pig muscle.
    Mesh-Begriff(e) Swine ; Animals ; Muscle, Skeletal/metabolism ; RNA-Seq ; Fatty Acids/metabolism ; Transcriptome ; Phenotype
    Chemische Substanzen Fatty Acids
    Sprache Englisch
    Erscheinungsdatum 2023-01-11
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-27016-x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Extra-uterine (abdominal) full term foetus in a 15-day pregnant rabbit

    Marco-Jiménez, Francisco / García-Domínguez, Ximo / Valdes-Hernández, Jesús / Vicente, José Salvador

    BMC veterinary research. 2017 Dec., v. 13, no. 1

    2017  

    Abstract: BACKGROUND: While ectopic pregnancies account for 1–2% of all pregnancies, abdominal pregnancy is extremely rare, accounting for approximately 1% of ectopic pregnancies. Extrauterine abdominal pregnancy is defined as the implantation and development of ... ...

    Abstract BACKGROUND: While ectopic pregnancies account for 1–2% of all pregnancies, abdominal pregnancy is extremely rare, accounting for approximately 1% of ectopic pregnancies. Extrauterine abdominal pregnancy is defined as the implantation and development of an embryo in the peritoneal cavity. The present report is the first of an incidental case of abdominal pregnancy within four full-term foetus simultaneously with 2 weeks of physiological gestation in a healthy doe rabbit. CASE PRESENTATION: The doe was born on November 3, 2014 and the first partum took place on May 18, 2015. The doe had previously delivered and weaned an average of 12.0 ± 1.41 live kits at birth (no stillbirths were recorded) during 5 consecutive pregnancies. The last mating was on December 18, 2015 and the detection of pregnancy failure post breeding (by abdominal palpation) on December 31, 2015. Then, the doe was artificially inseminated on January 27, 2016, diagnosed pregnant on February 11, 2016 and subsequently euthanized to recover the foetus. A ventral midline incision revealed a reproductive tract with 12 implantation sites with 15 days old foetus and 4 term foetus in abdominal cavity. There were two foetus floating on either side of the abdominal cavity and two suspended near the greater curvature of the stomach. They were attached to internal organs by means of one or 2 thread-like blood vessels that linked them to the abdominal surfaces. CONCLUSIONS: In our opinion a systematic monitoring of rabbit breeding should be included to fully understand and enhance current knowledge of this phenomenon of abdominal pregnancy.
    Schlagwörter abdominal cavity ; blood vessels ; breeding ; fetal death ; fetus ; monitoring ; pregnancy ; rabbits ; stomach ; veterinary medicine
    Sprache Englisch
    Erscheinungsverlauf 2017-12
    Umfang p. 307.
    Erscheinungsort BioMed Central
    Dokumenttyp Artikel
    ISSN 1746-6148
    DOI 10.1186/s12917-017-1229-7
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  7. Artikel ; Online: Extra-uterine (abdominal) full term foetus in a 15-day pregnant rabbit.

    Marco-Jiménez, Francisco / García-Domínguez, Ximo / Valdes-Hernández, Jesús / Vicente, José Salvador

    BMC veterinary research

    2017  Band 13, Heft 1, Seite(n) 307

    Abstract: Background: While ectopic pregnancies account for 1-2% of all pregnancies, abdominal pregnancy is extremely rare, accounting for approximately 1% of ectopic pregnancies. Extrauterine abdominal pregnancy is defined as the implantation and development of ... ...

    Abstract Background: While ectopic pregnancies account for 1-2% of all pregnancies, abdominal pregnancy is extremely rare, accounting for approximately 1% of ectopic pregnancies. Extrauterine abdominal pregnancy is defined as the implantation and development of an embryo in the peritoneal cavity. The present report is the first of an incidental case of abdominal pregnancy within four full-term foetus simultaneously with 2 weeks of physiological gestation in a healthy doe rabbit.
    Case presentation: The doe was born on November 3, 2014 and the first partum took place on May 18, 2015. The doe had previously delivered and weaned an average of 12.0 ± 1.41 live kits at birth (no stillbirths were recorded) during 5 consecutive pregnancies. The last mating was on December 18, 2015 and the detection of pregnancy failure post breeding (by abdominal palpation) on December 31, 2015. Then, the doe was artificially inseminated on January 27, 2016, diagnosed pregnant on February 11, 2016 and subsequently euthanized to recover the foetus. A ventral midline incision revealed a reproductive tract with 12 implantation sites with 15 days old foetus and 4 term foetus in abdominal cavity. There were two foetus floating on either side of the abdominal cavity and two suspended near the greater curvature of the stomach. They were attached to internal organs by means of one or 2 thread-like blood vessels that linked them to the abdominal surfaces.
    Conclusions: In our opinion a systematic monitoring of rabbit breeding should be included to fully understand and enhance current knowledge of this phenomenon of abdominal pregnancy.
    Mesh-Begriff(e) Animals ; Female ; Fetal Development ; Pregnancy ; Pregnancy, Abdominal/pathology ; Pregnancy, Abdominal/veterinary ; Rabbits
    Sprache Englisch
    Erscheinungsdatum 2017-11-03
    Erscheinungsland England
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 2191675-5
    ISSN 1746-6148 ; 1746-6148
    ISSN (online) 1746-6148
    ISSN 1746-6148
    DOI 10.1186/s12917-017-1229-7
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Use of Spline function for the characterisation on peak yield, peak day and persistency in lactation curves in Murciano-Granadina goats

    Miranda-Alejo, Judith Carmen / León-Jurado, José Manuel / Pieramati, Camillo / Gómez Carpio, Mayra Mercedes / Valdés-Hernández, Jesús / Barba-Capote, Cecilio José

    Italian journal of animal science. 2019 Jan. 2, v. 18, no. 1

    2019  

    Abstract: The objective of this study was to characterise the peak yield (PY), peak day (PD) and the persistency (P) of the lactation curve of Murciano-Granadina goats by Spline considering the variation factors (region, type of kidding, lactation number and ... ...

    Abstract The objective of this study was to characterise the peak yield (PY), peak day (PD) and the persistency (P) of the lactation curve of Murciano-Granadina goats by Spline considering the variation factors (region, type of kidding, lactation number and season) and their levels. A total of 1,349,347 test-day records from 180,872 lactations, of 85,404 goats were used. The analysed data with Spline model was considered for adequate fit in lactation curves for others traits in these goats. All factors affected the scale and/or shape of the lactation curve. In the region factor, significant differences (SD, p < .05) were observed in terms of the total milk yield (TY), final persistency (FP) and total persistency (TP) variables in favour of Almeria versus Cordoba and Granada; the PD variables, PY and initial persistency (IP) did not show SD (NSD, p > .05) between regions. The type of kidding presented SD among its levels (evident between double versus single and triple) with the exception of the PY. The lactation number for the variables of PD, PY and TY from second to fifth lactation showed NSD among themselves; but it did in the case of the first. The P of first lactation was longer, with a decrease in subsequent lactations. In the season factor, PD, TY and P presented SD; where the PD was divided into two groups: late group (winter-spring) and early group (fall-winter). The P, PY and PD can be considered as an additional selection criterion and thus modify the lactation curve.HighlightsThe biomodeling of individualized lactation curves is an important information resource for farmers and their breeding program. A conglomerate of microeffects such us climate, photoperiod, agroecological aspects, affect parameters of the lactation curve and their productions. It is preferable to achieve lactations with more emphasis on persistency in order to provide animal welfare and obtain adequate economic benefits.
    Schlagwörter Murcia-Granada ; agroecology ; animal welfare ; climate ; data analysis ; information sources ; lactation ; lactation curve ; lactation number ; milk yield ; models
    Sprache Englisch
    Erscheinungsverlauf 2019-0102
    Umfang p. 888-897.
    Erscheinungsort Taylor & Francis
    Dokumenttyp Artikel
    Anmerkung NAL-light
    ZDB-ID 2408994-1
    ISSN 1828-051X ; 1594-4077
    ISSN (online) 1828-051X
    ISSN 1594-4077
    DOI 10.1080/1828051X.2019.1593057
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