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  1. Article ; Online: MindReader

    Rivas-Carrillo, Salvador Daniel / Akkuratov, Evgeny E / Valdez Ruvalcaba, Hector / Vargas-Sanchez, Angel / Komorowski, Jan / San-Juan, Daniel / Grabherr, Manfred G

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 6

    Abstract: Electroencephalogram (EEG) interpretation plays a critical role in the clinical assessment of neurological conditions, most notably epilepsy. However, EEG recordings are typically analyzed manually by highly specialized and heavily trained personnel. ... ...

    Abstract Electroencephalogram (EEG) interpretation plays a critical role in the clinical assessment of neurological conditions, most notably epilepsy. However, EEG recordings are typically analyzed manually by highly specialized and heavily trained personnel. Moreover, the low rate of capturing abnormal events during the procedure makes interpretation time-consuming, resource-hungry, and overall an expensive process. Automatic detection offers the potential to improve the quality of patient care by shortening the time to diagnosis, managing big data and optimizing the allocation of human resources towards precision medicine. Here, we present
    MeSH term(s) Humans ; Electroencephalography/methods ; Epilepsy/diagnosis ; Neural Networks, Computer ; Fourier Analysis ; Unsupervised Machine Learning
    Language English
    Publishing date 2023-03-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23062971
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Neurophysiological Intraoperative Monitoring in the Elderly.

    De la Maza Krzeptowsky, Lilia C / San-Juan, Daniel / Ximénez Camilli, Cecilia / Alvarez Perera, Luis Á / Valdez Ruvalcaba, Hector / Morales Báez, Jorge A / Anschel, David J

    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society

    2020  Volume 38, Issue 3, Page(s) 231–236

    Abstract: Introduction: Intraoperative neurophysiological monitoring (IONM) is widely used to prevent nervous system injury during surgeries in elderly patients. However, there are no studies that describe the characteristics and changes in neurophysiological ... ...

    Abstract Introduction: Intraoperative neurophysiological monitoring (IONM) is widely used to prevent nervous system injury during surgeries in elderly patients. However, there are no studies that describe the characteristics and changes in neurophysiological tests during the IONM of patients aged 60 years and older. The study aims to describe and compare IONM changes during surgeries in adult patients aged 18 to 59 years with those aged 60 years and older.
    Methods: We performed a comparative retrospective study of patients aged 18 to 59 years versus those 60 aged years and older who underwent IONM during 2013 to 2018 in Mexico City. Sociodemographic characteristics were recorded and compared. Intraoperative neurophysiological monitoring techniques, their changes, and surgical procedures for both groups were analyzed and compared using descriptive statistics, Mann-Whitney U, Fisher, and χ2 tests. The sensitivity, specificity, and positive and negative predictive values were calculated.
    Results: In total, 195 patients were analyzed: 104 patients, 68.63 ± 6.54 years old (elderly group) and 91 patients, 42.3 ± 10.5 years old (younger group). No differences were found in the rates of signal change during IONM between the group of elderly patients and the younger group. The sensitivity, specificity, and positive and negative predictive values were 80%, 99%, 80%, and 99%, respectively.
    Conclusions: Elderly patients have a similar rate of changes in IONM signals compared with younger patients during heterogeneous surgeries guided by IONM.
    MeSH term(s) Adolescent ; Adult ; Aged ; Female ; Humans ; Intraoperative Neurophysiological Monitoring/methods ; Male ; Mexico ; Middle Aged ; Neurosurgical Procedures/methods ; Retrospective Studies ; Young Adult
    Language English
    Publishing date 2020-01-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605640-4
    ISSN 1537-1603 ; 0736-0258
    ISSN (online) 1537-1603
    ISSN 0736-0258
    DOI 10.1097/WNP.0000000000000689
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Continuous Visual Focal Status Epilepticus as the Primary Presentation of NMDA-R and GAD65-R Autoimmune Epilepsy.

    Paredes-Aragón, Elma M / Valdéz-Ruvalcaba, Héctor E / Santos-Peyret, Andrea / Cisneros-Otero, Marcela / Medina-Rioja, Raúl / Orozco-Suárez, Sandra / Hernandez, Miriam M / Breda-Yepes, Michele D L / Rivas-Alonso, Verónica / Flores-Rivera, José J / Martínez-Juárez, Iris E

    Frontiers in neurology

    2020  Volume 11, Page(s) 598974

    Abstract: Epilepsia partialis continua ( ... ...

    Abstract Epilepsia partialis continua (EPC
    Language English
    Publishing date 2020-11-26
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2020.598974
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Stroke Among SARS-CoV-2 Vaccine Recipients in Mexico: A Nationwide Descriptive Study.

    López-Mena, Diego / García-Grimshaw, Miguel / Saldivar-Dávila, Sergio / Hernandez-Vanegas, Laura Elena / Saniger-Alba, María Del Mar / Gutiérrez-Romero, Alonso / Carrillo-Mezo, Roger / Valdez-Ruvalcaba, Hector Eduardo / Cano-Nigenda, Vanessa / Flores-Silva, Fernando Daniel / Cantú-Brito, Carlos / Santibañez-Copado, Ana María / Diaz-Ortega, Jose-Luis / Ceballos-Liceaga, Santa Elizabeth / Murillo-Bonilla, Luis Manuel / Sepulveda-Núñez, Ana Isabel / García-Talavera, Verónica / Gonzalez-Guerra, Eduardo / Cortes-Alcala, Ricardo /
    Lopez-Gatell, Hugo / Carbajal-Sandoval, Guillermo / Reyes-Terán, Gustavo / Valdés-Ferrer, Sergio Iván / Arauz, Antonio

    Neurology

    2022  Volume 98, Issue 19, Page(s) e1933–e1941

    Abstract: Background and objectives: Information on stroke among severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines remains scarce. We report stroke incidence as an adverse event following immunization (AEFI) among recipients of 79,399,446 ... ...

    Abstract Background and objectives: Information on stroke among severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines remains scarce. We report stroke incidence as an adverse event following immunization (AEFI) among recipients of 79,399,446 doses of 6 different SARS-CoV-2 vaccines (BNT162b2, ChAdOx1 nCov-19, Gam-COVID-Vac, CoronaVac, Ad5-nCoV, and Ad26.COV2-S) between December 24, 2020, and August 31, 2021, in Mexico.
    Methods: This retrospective descriptive study analyzed stroke incidence per million doses among hospitalized adult patients (≥18 years) during an 8-month interval. According to the World Health Organization, AEFIs were defined as clinical events occurring within 30 days after immunization and categorized as either nonserious or serious, depending on severity, treatment, and hospital admission requirements. Acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH), and cerebral venous thrombosis (CVT) cases were collected through a passive epidemiologic surveillance system in which local health providers report potential AEFI to the Mexican General Board of Epidemiology. Data were captured with standardized case report formats by an ad hoc committee appointed by the Mexican Ministry of Health to evaluate potential neurologic AEFI against SARS-COV-2.
    Results: We included 56 patients (31 female patients [55.5%]) for an overall incidence of 0.71 cases per 1,000,000 administered doses (95% CI 0.54-0.92). Median age was 65 years (interquartile range [IQR] 55-76 years); median time from vaccination to stroke (of any subtype) was 2 days (IQR 1-5 days). In 27 (48.2%) patients, the event was diagnosed within the first 24 hours after immunization. The most frequent subtype was AIS in 43 patients (75%; 0.54 per 1,000,000 doses, 95% CI 0.40-0.73), followed by ICH in 9 (16.1%; 0.11 per 1,000,000 doses, 95% CI 0.06-0.22) and SAH and CVT, each with 2 cases (3.6%; 0.03 per 1,000,000 doses, 95% CI 0.01-0.09). Overall, the most common risk factors were hypertension in 33 (58.9%) patients and diabetes in 22 (39.3%). Median hospital length of stay was 6 days (IQR 4-13 days). At discharge, functional outcome was good (modified Rankin Scale score 0-2) in 41.1% of patients; in-hospital mortality rate was 21.4%.
    Discussion: Stroke is an exceedingly rare AEFI against SARS-CoV-2. Preexisting stroke risk factors were identified in most patients. Further research is needed to evaluate causal associations between SARS-COV-2 vaccines and stroke.
    MeSH term(s) Aged ; BNT162 Vaccine ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; ChAdOx1 nCoV-19 ; Female ; Humans ; Ischemic Stroke/epidemiology ; Male ; Mexico/epidemiology ; Middle Aged ; Retrospective Studies ; SARS-CoV-2 ; Vaccination/adverse effects
    Chemical Substances COVID-19 Vaccines ; ChAdOx1 nCoV-19 (B5S3K2V0G8) ; BNT162 Vaccine (N38TVC63NU)
    Language English
    Publishing date 2022-03-11
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000200388
    Database MEDical Literature Analysis and Retrieval System OnLINE

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