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  1. Article ; Online: Evaluation of the efficacy and safety of single incision sling vs TVT-O in obese patients with stress urinary incontinence: Quality of life and sexual function analysis.

    Schiavi, Michele Carlo / Carletti, Valerio / Yacoub, Veronica / Cardella, Giorgia / Luffarelli, Paolo / Valensise, Herbert Carmelo Carlo / Palazzetti, Pierluigi / Spina, Vincenzo / Zullo, Marzio Angelo

    Taiwanese journal of obstetrics & gynecology

    2023  Volume 62, Issue 1, Page(s) 89–93

    Abstract: Objectives: The aim of the study is to demonstrate the best stress urinary incontinence (SUI) surgical technique for women with a Body mass index higher than 30. The results of Transvaginal Tension Free Vaginal Tape-Obturator and Mini-sling surgery were ...

    Abstract Objectives: The aim of the study is to demonstrate the best stress urinary incontinence (SUI) surgical technique for women with a Body mass index higher than 30. The results of Transvaginal Tension Free Vaginal Tape-Obturator and Mini-sling surgery were analyzed and compared through both clinical examination and standardized questionnaires at 36 months of follow-up.
    Materials and methods: This is a retrospective multicenter study over 159 women with SUI who underwent surgery. Seventy-eight women underwent TVT-O and 81 Mini-sling technique. Intra and post-operative complications were recorded. Patients were monitored for 36 months by analyzing symptoms, voiding diary, quality of life and sexual activity through standardized questionnaires.
    Results: Complications had a low incidence in both groups and inter-group differences were superimposable. Only groin pain was statistically higher after TVT-O than after Mini-sling (12.8% vs1.2%, p = 0.03). At 36 months of follow-up, a statistically significant decrease in Positive stress test (%) and Q-Tip test (grade) was observed in both groups with no differences between them (p = 0.54 and p = 0.32 respectively). The mean number of daily voids was higher after TVT-O (p = 0.04) than after Altis (p = 0.22) with a significant difference in favor of the Altis group (p = 0.03). After 36 months, there were no significant differences between groups in terms of quality of life and sexual activity. PGI-I did not show any difference between groups (p = 0.21).
    Conclusion: TVT-O and Minisling had the same efficacy and results in the surgical treatment of SUI in obese women. Both techniques relieved their symptoms and improved their quality of life without any significant difference except for a lower incidence of post- Mini-sling complications.
    MeSH term(s) Humans ; Female ; Urinary Incontinence, Stress/surgery ; Treatment Outcome ; Quality of Life ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Suburethral Slings/adverse effects
    Language English
    Publishing date 2023-01-31
    Publishing country China (Republic : 1949- )
    Document type Multicenter Study ; Journal Article
    ZDB-ID 2202946-1
    ISSN 1875-6263 ; 1875-6263
    ISSN (online) 1875-6263
    ISSN 1875-6263
    DOI 10.1016/j.tjog.2022.07.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Quality of life and sexual function analysis in a group of Italian postmenopausal women after COVID-19 vaccination.

    Yacoub, Veronica / Carletti, Valerio / Grilli, Debora / Morgani, Claudia / Palazzetti, Pierluigi / Zullo, Marzio Angelo / Luffarelli, Paolo / Valensise, Herbert Carmelo Carlo / Schiavi, Michele Carlo

    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology

    2022  , Page(s) 1–4

    Abstract: Aim: The aim of the study was to evaluate the impact of SARS-CoV-2 vaccination on quality of life, psychological aspect and sexual life in a group of Italian postmenopausal women during the COVID-19 pandemic.: Methods: The study was a prospective, ... ...

    Abstract Aim: The aim of the study was to evaluate the impact of SARS-CoV-2 vaccination on quality of life, psychological aspect and sexual life in a group of Italian postmenopausal women during the COVID-19 pandemic.
    Methods: The study was a prospective, observational analysis of postmenopausal women before and after the COVID-19 vaccination. The population previously answered different questionnaires, such as the Female Sexual Function Index (FSFI), the Female Sexual Distress Scale (FSDS), the 36-Item Short Form Survey (SF-36) and the Hospital Anxiety and Depression Scale (HADS). Twelve weeks after the end of the vaccine cycle, these women were invited to complete the same questionnaires by e-mail to evaluate if vaccination coverage could positively impact the quality of life of postmenopausal women. The Patient Impression of Global Improvement (PGI-I) after three months of treatment was also calculated.
    Results: A total of 114 patients were reported. The median age was 60.96 (52-66) years. Mean sexual intercourses/month increased from 1.28 ± 1.23 to 4.21 ± 1.80 (
    Conclusions: The spread of COVID-19 vaccine coverage positively influenced sexual function, quality of life and psychological aspect in postmenopausal women.
    Language English
    Publishing date 2022-10-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 639237-4
    ISSN 1473-0766 ; 0951-3590
    ISSN (online) 1473-0766
    ISSN 0951-3590
    DOI 10.1080/09513590.2022.2132224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: TOT in combination with solifenacin or intravaginal prasterone in postmenopausal women with mixed urinary incontinence: A retrospective analysis in 112 patients.

    Sala, Federica / Loggia, Melania / Cardella, Giorgia / Morgani, Claudia / Grossi, Giovanni / Zullo, Marzio Angelo / Valensise, Herbert Carmelo Carlo / Palazzetti, Pier Luigi / Schiavi, Michele Carlo

    Lower urinary tract symptoms

    2023  Volume 15, Issue 3, Page(s) 96–101

    Abstract: Objectives: The aim of this study was to compare the efficacy of the transobturator tape (TOT) procedure combined with solifenacin (TOT-S) or prasterone (TOT-P) in postmenopausal women affected by mixed urinary incontinence (MUI) with a predominant ... ...

    Abstract Objectives: The aim of this study was to compare the efficacy of the transobturator tape (TOT) procedure combined with solifenacin (TOT-S) or prasterone (TOT-P) in postmenopausal women affected by mixed urinary incontinence (MUI) with a predominant stress urinary incontinence component.
    Methods: This is a retrospective analysis including 112 patients: 60 patients of the TOT-S group and 52 patients of the TOT-P group. Physical examination, 3-day voiding diary, urodynamic tests, and Vaginal Health Index (VHI) were compared at the beginning of the analysis and after 12 weeks of follow-up (FU). Specific questionnaires were administered to indagate the impact on women's quality of life and sexual function.
    Results: After 12 weeks of FU, the detrusor's peak flow pressure was significantly different between the two groups (p = .02). Detrusor overactivity decreased only in the TOT-P group (p = .05). At the end of FU, 58 patients (96.7%) of the TOT-S group and 50 patients (96.2%) of the TOT-P group were dry at the stress test. A significative group difference was observed in urge urinary incontinence (24 h) (p = .01) but not in the mean number of voids (24 h) and urgent micturition events (24 h). VHI improved only in the TOT-P group (12.57 ± 3.80 vs. 19.75 ± 4.13, p < .0001). The questionnaires and Patient Global Index of Improvement (PGI-I) scores showed comparable improvements, while the Female Sexual Function Index improved especially in the TOT-P group (p < .001).
    Conclusions: In postmenopausal women with MUI, TOT-P demonstrated the same effectiveness as TOT-S in reducing urinary symptoms. In addition, TOT-P increased VHI and sexual function scores compared with TOT-S.
    MeSH term(s) Humans ; Female ; Urinary Incontinence, Stress/drug therapy ; Solifenacin Succinate/therapeutic use ; Retrospective Studies ; Treatment Outcome ; Dehydroepiandrosterone ; Postmenopause ; Suburethral Slings ; Quality of Life ; Urinary Incontinence, Urge
    Chemical Substances Solifenacin Succinate (KKA5DLD701) ; Dehydroepiandrosterone (459AG36T1B)
    Language English
    Publishing date 2023-03-04
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2519111-1
    ISSN 1757-5672 ; 1757-5664
    ISSN (online) 1757-5672
    ISSN 1757-5664
    DOI 10.1111/luts.12476
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Mature Ovarian Teratoma: Neurological Implications in a Young Woman.

    Schiavi, Michele Carlo / Manganelli, Fabio / Morgani, Claudia / Cignini, Pietro / Yacoub, Veronica / Carletti, Valerio / Grilli, Debora / Di Pinto, Anna / Bisogni, Francesco / Ligato, Azzurra / Galanti, Francesco / Valensise, Herbert Carmelo Carlo / Palazzetti, Pier Luigi

    Case reports in obstetrics and gynecology

    2021  Volume 2021, Page(s) 3085559

    Abstract: Anti-NMDAR encephalitis is an autoimmune syndrome associated with antibodies against NMDA receptors. In some cases, it is associated with various tumors; one of them is ovarian teratoma, which mostly affects women below the age of 30 years. Here, we ... ...

    Abstract Anti-NMDAR encephalitis is an autoimmune syndrome associated with antibodies against NMDA receptors. In some cases, it is associated with various tumors; one of them is ovarian teratoma, which mostly affects women below the age of 30 years. Here, we report a case of ovarian teratoma associated with anti-NMDAR encephalitis treated with both laparoscopic surgery and immunotherapy. Multidisciplinary approach is the cornerstone for the management of this syndrome.
    Language English
    Publishing date 2021-11-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2627654-9
    ISSN 2090-6692 ; 2090-6684
    ISSN (online) 2090-6692
    ISSN 2090-6684
    DOI 10.1155/2021/3085559
    Database MEDical Literature Analysis and Retrieval System OnLINE

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