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  1. Article: Middle-third clavicle fracture with associated type IV acromioclavicular separation: case report and literature review.

    Woolf, Shane K / Valentine, Brandon J / Barfield, William R / Hartsock, Langdon A

    Journal of surgical orthopaedic advances

    2013  Volume 22, Issue 2, Page(s) 183–186

    Abstract: Review of available English literature suggests that combined injuries involving a clavicle shaft fracture and an acromioclavicular (AC) separation are rare. The force dissipation after the occurrence of either a midshaft clavicle fracture or an AC ... ...

    Abstract Review of available English literature suggests that combined injuries involving a clavicle shaft fracture and an acromioclavicular (AC) separation are rare. The force dissipation after the occurrence of either a midshaft clavicle fracture or an AC separation typically renders the injuries mutually exclusive. This article presents a review of literature on this combined injury pattern. A variety of treatment approaches have been put forth, including nonoperative, operative, and hybrid management of the two distinct injuries. The most appropriate treatment rendered depends on the degree of AC joint instability. This case report involves a midshaft clavicle fracture associated with a type IV AC separation in a patient ejected during a high-speed motor vehicle collision. Internal fixation of each injury was chosen and the patient had a successful final result. Other reported treatment options and recommendations are reviewed.
    MeSH term(s) Acromioclavicular Joint/injuries ; Adult ; Clavicle/injuries ; Female ; Fracture Fixation, Internal ; Fractures, Bone/complications ; Fractures, Bone/surgery ; Humans ; Joint Dislocations/complications ; Joint Dislocations/surgery
    Language English
    Publishing date 2013-04-25
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2189157-6
    ISSN 2158-3811 ; 1548-825X ; 1059-1052
    ISSN (online) 2158-3811
    ISSN 1548-825X ; 1059-1052
    DOI 10.3113/jsoa.2013.0183
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4751: Show issues Location:
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  2. Article ; Online: A critical examination of popular assumptions about the benefits and outcomes of monogamous relationships.

    Conley, Terri D / Ziegler, Ali / Moors, Amy C / Matsick, Jes L / Valentine, Brandon

    Personality and social psychology review : an official journal of the Society for Personality and Social Psychology, Inc

    2013  Volume 17, Issue 2, Page(s) 124–141

    Abstract: In this article, we critically examine the social institution of monogamy. First, we discuss the lack of an adequate and consistent definition of the construct of monogamy and consider how common monogamy is. Next, we address perceived benefits of ... ...

    Abstract In this article, we critically examine the social institution of monogamy. First, we discuss the lack of an adequate and consistent definition of the construct of monogamy and consider how common monogamy is. Next, we address perceived benefits of monogamy and whether those ostensible benefits are supported by empirical evidence. We conclude that evidence for the benefits of monogamy relative to other relationship styles is currently lacking, suggesting that, for those who choose it, consensual non-monogamy may be a viable alternative to monogamy. Implications for theories of close relationships are discussed.
    MeSH term(s) Adaptation, Psychological ; Animals ; Cross-Sectional Studies ; Extramarital Relations/psychology ; Female ; Gender Identity ; HIV Infections/prevention & control ; HIV Infections/psychology ; HIV Infections/transmission ; Homosexuality/psychology ; Homosexuality/statistics & numerical data ; Humans ; Interpersonal Relations ; Jealousy ; Love ; Male ; Marriage/psychology ; Marriage/statistics & numerical data ; Mythology ; Parenting/psychology ; Personal Satisfaction ; Psychological Theory ; Sexual Partners/psychology ; Sexually Transmitted Diseases/prevention & control ; Sexually Transmitted Diseases/psychology ; Sexually Transmitted Diseases/transmission ; Social Values ; Unsafe Sex/psychology ; Unsafe Sex/statistics & numerical data
    Language English
    Publishing date 2013-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2022092-3
    ISSN 1532-7957 ; 1088-8683
    ISSN (online) 1532-7957
    ISSN 1088-8683
    DOI 10.1177/1088868312467087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A global metagenomic map of urban microbiomes and antimicrobial resistance.

    Danko, David / Bezdan, Daniela / Afshin, Evan E / Ahsanuddin, Sofia / Bhattacharya, Chandrima / Butler, Daniel J / Chng, Kern Rei / Donnellan, Daisy / Hecht, Jochen / Jackson, Katelyn / Kuchin, Katerina / Karasikov, Mikhail / Lyons, Abigail / Mak, Lauren / Meleshko, Dmitry / Mustafa, Harun / Mutai, Beth / Neches, Russell Y / Ng, Amanda /
    Nikolayeva, Olga / Nikolayeva, Tatyana / Png, Eileen / Ryon, Krista A / Sanchez, Jorge L / Shaaban, Heba / Sierra, Maria A / Thomas, Dominique / Young, Ben / Abudayyeh, Omar O / Alicea, Josue / Bhattacharyya, Malay / Blekhman, Ran / Castro-Nallar, Eduardo / Cañas, Ana M / Chatziefthimiou, Aspassia D / Crawford, Robert W / De Filippis, Francesca / Deng, Youping / Desnues, Christelle / Dias-Neto, Emmanuel / Dybwad, Marius / Elhaik, Eran / Ercolini, Danilo / Frolova, Alina / Gankin, Dennis / Gootenberg, Jonathan S / Graf, Alexandra B / Green, David C / Hajirasouliha, Iman / Hastings, Jaden J A / Hernandez, Mark / Iraola, Gregorio / Jang, Soojin / Kahles, Andre / Kelly, Frank J / Knights, Kaymisha / Kyrpides, Nikos C / Łabaj, Paweł P / Lee, Patrick K H / Leung, Marcus H Y / Ljungdahl, Per O / Mason-Buck, Gabriella / McGrath, Ken / Meydan, Cem / Mongodin, Emmanuel F / Moraes, Milton Ozorio / Nagarajan, Niranjan / Nieto-Caballero, Marina / Noushmehr, Houtan / Oliveira, Manuela / Ossowski, Stephan / Osuolale, Olayinka O / Özcan, Orhan / Paez-Espino, David / Rascovan, Nicolás / Richard, Hugues / Rätsch, Gunnar / Schriml, Lynn M / Semmler, Torsten / Sezerman, Osman U / Shi, Leming / Shi, Tieliu / Siam, Rania / Song, Le Huu / Suzuki, Haruo / Court, Denise Syndercombe / Tighe, Scott W / Tong, Xinzhao / Udekwu, Klas I / Ugalde, Juan A / Valentine, Brandon / Vassilev, Dimitar I / Vayndorf, Elena M / Velavan, Thirumalaisamy P / Wu, Jun / Zambrano, María M / Zhu, Jifeng / Zhu, Sibo / Mason, Christopher E

    Cell

    2021  Volume 184, Issue 13, Page(s) 3376–3393.e17

    Abstract: We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an annotated, geospatial profile of ... ...

    Abstract We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an annotated, geospatial profile of microbial strains, functional characteristics, antimicrobial resistance (AMR) markers, and genetic elements, including 10,928 viruses, 1,302 bacteria, 2 archaea, and 838,532 CRISPR arrays not found in reference databases. We identified 4,246 known species of urban microorganisms and a consistent set of 31 species found in 97% of samples that were distinct from human commensal organisms. Profiles of AMR genes varied widely in type and density across cities. Cities showed distinct microbial taxonomic signatures that were driven by climate and geographic differences. These results constitute a high-resolution global metagenomic atlas that enables discovery of organisms and genes, highlights potential public health and forensic applications, and provides a culture-independent view of AMR burden in cities.
    MeSH term(s) Biodiversity ; Databases, Genetic ; Drug Resistance, Bacterial/genetics ; Humans ; Metagenomics ; Microbiota/genetics ; Urban Population
    Language English
    Publishing date 2021-05-26
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 187009-9
    ISSN 1097-4172 ; 0092-8674
    ISSN (online) 1097-4172
    ISSN 0092-8674
    DOI 10.1016/j.cell.2021.05.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1167: Show issues Location:
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  4. Article: Effect of green tea extract on cardiac hypertrophy following 5/6 nephrectomy in the rat.

    Priyadarshi, Snigdha / Valentine, Brandon / Han, Chi / Fedorova, Olga V / Bagrov, Alexei Y / Liu, Jiang / Periyasamy, Sankaridrug M / Kennedy, David / Malhotra, Deepak / Xie, Zijian / Shapiro, Joseph I

    Kidney international

    2003  Volume 63, Issue 5, Page(s) 1785–1790

    Abstract: Background: Left ventricular hypertrophy commonly complicates chronic renal failure. We have observed that at least one pathway of left ventricular hypertrophy appears to involve signaling through reactive oxygen species (ROS). Green tea is a substance ... ...

    Abstract Background: Left ventricular hypertrophy commonly complicates chronic renal failure. We have observed that at least one pathway of left ventricular hypertrophy appears to involve signaling through reactive oxygen species (ROS). Green tea is a substance that appears to have substantial antioxidant activity, yet is safe and is currently widely used. We, therefore, studied whether green tea supplementation could attenuate the development of left ventricular hypertrophy in an animal model of chronic renal failure.
    Methods: Male Sprague-Dawley rats were subjected to sham or remnant kidney surgery and given green tea extract (0.1% and 0.25%) or plain drinking water for the next 4 weeks. Heart weight, body weight, and cardiac Na-K-ATPase activity were measured at the end of this period. To further test our hypothesis, we performed studies in cardiac myocytes isolated from adult male Sprague-Dawley rats. We measured the generation of ROS using the oxidant sensitive dye dichlorofluorescein (DCF) as well as (3H)phenylalanine incorporation following exposure to cardiac glycosides with and without green tea extract.
    Results: Administration of green tea extract at 0.25% resulted in attenuation of left ventricular hypertrophy, hypertension, and preserved cardiac Na-K-ATPase activity in rats subjected to remnant kidney surgery (all P < 0.01). In subsequent studies performed in isolated cardiac myocytes, both ouabain and marinobufagenin (MBG) were both found to increase ROS production and (3H)phenylalanine incorporation at concentrations substantially below their inhibitor concentration (IC) 50 for the sodium pump. Addition of green tea extract prevented increases in ROS production as well as (3H)phenylalanine incorporation in these isolated cardiac myocytes.
    Conclusion: Green tea extract appears to block the development of cardiac hypertrophy in experimental renal failure. Some of this effect may be related to the attenuation of hypertension, but a direct effect on cardiac myocyte ROS production and growth was also identified. Clinical studies of green tea extract in chronic renal failure patients may be warranted.
    MeSH term(s) Animals ; Blood Pressure/drug effects ; Bufanolides/blood ; Cardenolides ; Cell Division/drug effects ; Cells, Cultured ; Digoxin/blood ; Disease Models, Animal ; Enzyme Activation/drug effects ; Hypertrophy, Left Ventricular/drug therapy ; Hypertrophy, Left Ventricular/etiology ; Hypertrophy, Left Ventricular/pathology ; Kidney Failure, Chronic/complications ; Male ; Myocardium/cytology ; Myocardium/pathology ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/metabolism ; Nephrectomy ; Phytotherapy ; Plant Extracts/pharmacology ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Rubidium Radioisotopes ; Saponins/blood ; Sodium-Potassium-Exchanging ATPase/metabolism ; Tea
    Chemical Substances Bufanolides ; Cardenolides ; Plant Extracts ; Reactive Oxygen Species ; Rubidium Radioisotopes ; Saponins ; Tea ; digoxin-like factors ; marinobufagenin (3KBT25GV2B) ; Digoxin (73K4184T59) ; Sodium-Potassium-Exchanging ATPase (EC 3.6.3.9)
    Language English
    Publishing date 2003-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1046/j.1523-1755.2003.00914.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 797: Show issues Location:
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  5. Article ; Online: Global Genetic Cartography of Urban Metagenomes and Anti-Microbial Resistance

    Danko, David / Bezdan, Daniela / Afshinnekoo, Ebrahim / Ahsanuddin, Sofia / Bhattacharya, Chandrima / Butler, Daniel J / Chng, Kern Rei / Donnellan, Daisy / Hecht, Jochen / Kuchin, Katerina / Karasikov, Mikhail / Lyons, Abigail / Mak, Lauren / Meleshko, Dmitry / Mustafa, Harun / Mutai, Beth / Neches, Russell Y / Ng, Amanda / Nikolayeva, Olga /
    Nikolayeva, Tatyana / Png, Eileen / Ryon, Krista / Sanchez, Jorge L / Shaaban, Heba / Sierra, Maria A / Thomas, Dominique / Young, Ben / Abudayyeh, Omar O. / Alicea, Josue / Bhattacharyya, Malay / Blekhman, Ran / Castro-Nallar, Eduardo / Cañas, Ana M / Chatziefthimiou, Aspassia D / Crawford, Robert W / De Filippis, Francesca / Deng, Youping / Desnues, Christelle / Dias-Neto, Emmanuel / Dybwad, Marius / Elhaik, Eran / Ercolini, Danilo / Frolova, Alina / Gankin, Dennis / Gootenberg, Jonathan S. / Graf, Alexandra B / Green, David C / Hajirasouliha, Iman / Hernandez, Mark / Iraola, Gregorio / Jang, Soojin / Kahles, Andre / Kelly, Frank J / Knights, Kaymisha / Kyrpides, Nikos C / Łabaj, Paweł P / Lee, Patrick K H / Leung, Marcus H Y / Ljungdahl, Per / Mason-Buck, Gabriella / McGrath, Ken / Meydan, Cem / Mongodin, Emmanuel F / Moraes, Milton Ozorio / Nagarajan, Niranjan / Nieto-Caballero, Marina / Noushmehr, Houtan / Oliveira, Manuela / Ossowski, Stephan / Osuolale, Olayinka O / Özcan, Orhan / Paez-Espino, David / Rascovan, Nicolas / Richard, Hugues / Rätsch, Gunnar / Schriml, Lynn M / Semmler, Torsten / Sezerman, Osman U / Shi, Leming / Shi, Tieliu / Song, Le Huu / Suzuki, Haruo / Tighe, Scott W / Tong, Xinzhao / Udekwu, Klas I / Ugalde, Juan A / Valentine, Brandon / Vassilev, Dimitar I / Vayndorf, Elena / Velavan, Thirumalaisamy P / Wu, Jun / Zambrano, María M / Zhu, Jifeng / Zhu, Sibo / Mason, Christopher E

    bioRxiv

    Abstract: Although studies have shown that urban environments and mass-transit systems have distinct genetic profiles, there are no systematic worldwide studies of these dense, human microbial ecosystems. To address this gap in knowledge, we created a global ... ...

    Abstract Although studies have shown that urban environments and mass-transit systems have distinct genetic profiles, there are no systematic worldwide studies of these dense, human microbial ecosystems. To address this gap in knowledge, we created a global metagenomic and antimicrobial resistance (AMR) atlas of urban mass transit systems from 60 cities, spanning 4,728 samples and 4,424 taxonomically-defined microorganisms collected for three years. This atlas provides an annotated, geospatial profile of microbial strains, functional characteristics, antimicrobial resistance markers, and novel genetic elements, including 10,928 novel predicted viral species, 1302 novel bacteria, and 2 novel archaea. Urban microbiomes often resemble human commensal microbiomes from the skin and airways, but also contain a consistent “core” of 31 species which are predominantly not human commensal species. Samples show distinct microbial signatures which may be used to accurately predict properties of their city of origin including population, proximity to the coast, and taxonomic profile. These data also show that AMR density across cities varies by several orders of magnitude, including many AMRs present on plasmids with cosmopolitan distributions. Together, these results constitute a high-resolution, global metagenomic atlas, which enables the discovery of new genetic components of the built human environment, highlights potential forensic applications, and provides an essential first draft of the global AMR burden of the world’s cities.
    Keywords covid19
    Publisher BioRxiv
    Document type Article ; Online
    DOI 10.1101/724526
    Database COVID19

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  6. Article: A global metagenomic map of urban microbiomes and antimicrobial resistance

    Danko, David / Bezdan, Daniela / Afshin, Evan E / Ahsanuddin, Sofia / Bhattacharya, Chandrima / Butler, Daniel J / Chng, Kern Rei / Donnellan, Daisy / Hecht, Jochen / Jackson, Katelyn / Kuchin, Katerina / Karasikov, Mikhail / Lyons, Abigail / Mak, Lauren / Meleshko, Dmitry / Mustafa, Harun / Mutai, Beth / Neches, Russell Y / Ng, Amanda /
    Nikolayeva, Olga / Nikolayeva, Tatyana / Png, Eileen / Ryon, Krista A / Sanchez, Jorge L / Shaaban, Heba / Sierra, Maria A / Thomas, Dominique / Young, Ben / Abudayyeh, Omar O / Alicea, Josue / Bhattacharyya, Malay / Blekhman, Ran / Castro-Nallar, Eduardo / Cañas, Ana M / Chatziefthimiou, Aspassia D / Crawford, Robert W / De Filippis, Francesca / Deng, Youping / Desnues, Christelle / Dias-Neto, Emmanuel / Dybwad, Marius / Elhaik, Eran / Ercolini, Danilo / Frolova, Alina / Gankin, Dennis / Gootenberg, Jonathan S / Graf, Alexandra B / Green, David C / Hajirasouliha, Iman / Hastings, Jaden J.A / Hernandez, Mark / Iraola, Gregorio / Jang, Soojin / Kahles, Andre / Kelly, Frank J / Knights, Kaymisha / Kyrpides, Nikos C / Łabaj, Paweł P / Lee, Patrick K.H / Leung, Marcus H.Y / Ljungdahl, Per O / Mason-Buck, Gabriella / McGrath, Ken / Meydan, Cem / Mongodin, Emmanuel F / Moraes, Milton Ozorio / Nagarajan, Niranjan / Nieto-Caballero, Marina / Noushmehr, Houtan / Oliveira, Manuela / Ossowski, Stephan / Osuolale, Olayinka O / Özcan, Orhan / Paez-Espino, David / Rascovan, Nicolás / Richard, Hugues / Rätsch, Gunnar / Schriml, Lynn M / Semmler, Torsten / Sezerman, Osman U / Shi, Leming / Shi, Tieliu / Siam, Rania / Song, Le Huu / Suzuki, Haruo / Court, Denise Syndercombe / Tighe, Scott W / Tong, Xinzhao / Udekwu, Klas I / Ugalde, Juan A / Valentine, Brandon / Vassilev, Dimitar I / Vayndorf, Elena M / Velavan, Thirumalaisamy P / Wu, Jun / Zambrano, María M / Zhu, Jifeng / Zhu, Sibo / Mason, Christopher E / Abdullah, Natasha / Abraao, Marcos / Adel, Ait-hamlat / Afaq, Muhammad / Al-Quaddoomi, Faisal S / Alam, Ireen / Albuquerque, Gabriela E / Alexiev, Alex / Ali, Kalyn / Alvarado-Arnez, Lucia E / Aly, Sarh / Amachee, Jennifer / Amorim, Maria G / Ampadu, Majelia / Amran, Muhammad Al-Fath / An, Nala / Andrew, Watson / Andrianjakarivony, Harilanto / Angelov, Michael / Antelo, Verónica / Aquino, Catharine / Aranguren, Álvaro / Araujo, Luiza F / Vasquez Arevalo, Hitler Francois / Arevalo, Jenny / Arnan, Carme / Alvarado Arnez, Lucia Elena / Arredondo, Fernanda / Arthur, Matthew / Asenjo, Freddy / Aung, Thomas Saw / Auvinet, Juliette / Aventin, Nuria / Ayaz, Sadaf / Baburyan, Silva / Bakere, Abd-Manaaf / Bakhl, Katrin / Bartelli, Thais F / Batdelger, Erdenetsetseg / Baudon, François / Becher, Kevin / Bello, Carla / Benchouaia, Médine / Benisty, Hannah / Benoiston, Anne-Sophie / Benson, Joseph / Benítez, Diego / Bernardes, Juliana / Bertrand, Denis / Beurmann, Silvia / Bitard-Feildel, Tristan / Bittner, Lucie / Black, Christina / Blanc, Guillaume / Blyther, Brittany / Bode, Toni / Boeri, Julia / Boldgiv, Bazartseren / Bolzli, Kevin / Bordigoni, Alexia / Borrelli, Ciro / Bouchard, Sonia / Bouly, Jean-Pierre / Boyd, Alicia / Branco, Gabriela P / Breschi, Alessandra / Brindefalk, Björn / Brion, Christian / Briones, Alan / Buczansla, Paulina / Burke, Catherine M / Burrell, Aszia / Butova, Alina / Buttar, Irvind / Bynoe, Jalia / Bönigk, Sven / Bøifot, Kari O / Caballero, Hiram / Cai, Xiao Wen / Calderon, Dayana / Cantillo, Angela / Carbajo, Miguel / Carbone, Alessandra / Cardenas, Anais / Carrillo, Katerine / Casalot, Laurie / Castro, Sofia / Castro, Ana V / Castro, Astred / Castro, Ana Valeria B / Cawthorne, Simone / Cedillo, Jonathan / Chaker, Salama / Chalangal, Jasna / Chan, Allison / Chasapi, Anastasia I / Chatziefthimiou, Starr / Chaudhuri, Sreya Ray / Chavan, Akash Keluth / Chavez, Francisco / Chem, Gregory / Chen, Xiaoqing / Chen, Michelle / Chen, Jenn-Wei / Chernomoretz, Ariel / Chettouh, Allaeddine / Cheung, Daisy / Chicas, Diana / Chiu, Shirley / Choudhry, Hira / Chrispin, Carl / Ciaramella, Kianna / Cifuentes, Erika / Cohen, Jake / Coil, David A / Collin, Sylvie / Conger, Colleen / Conte, Romain / Corsi, Flavia / Cossio, Cecilia N / Costa, Ana F / Cuebas, Delisia / D’Alessandro, Bruno / Dahlhausen, Katherine E / Darling, Aaron E / Das, Pujita / Davenport, Lucinda B / David, Laurent / Davidson, Natalie R / Dayama, Gargi / Delmas, Stéphane / Deng, Chris K / Dequeker, Chloé / Desert, Alexandre / Devi, Monika / Dezem, Felipe S / Dias, Clara N / Donahoe, Timothy Ryan / Dorado, Sonia / Dorsey, LaShonda / Dotsenko, Valeriia / Du, Steven / Dutan, Alexandra / Eady, Naya / Eisen, Jonathan A / Elaskandrany, Miar / Epping, Lennard / Escalera-Antezana, Juan P / Ettinger, Cassie L / Faiz, Iqra / Fan, Luice / Farhat, Nadine / Faure, Emile / Fauzi, Fazlina / Feigin, Charlie / Felice, Skye / Ferreira, Laís Pereira / Figueroa, Gabriel / Fleiss, Aubin / Flores, Denisse / Velasco Flores, Jhovana L / Fonseca, Marcos A.S / Foox, Jonathan / Forero, Juan Carlos / Francis, Aaishah / French, Kelly / Fresia, Pablo / Friedman, Jacob / Fuentes, Jaime J / Galipon, Josephine / Garcia, Mathilde / Garcia, Laura / García, Catalina / Geiger, Annie / Gerner, Samuel M / Ghose, Sonia L / Giang, Dao Phuong / Giménez, Matías / Giovannelli, Donato / Githae, Dedan / Gkotzis, Spyridon / Godoy, Liliana / Goldman, Samantha / Gonnet, Gaston H / Gonzalez, Juana / Gonzalez, Andrea / Gonzalez-Poblete, Camila / Gray, Andrew / Gregory, Tranette / Greselle, Charlotte / Guasco, Sophie / Guerra, Juan / Gurianova, Nika / Haehr, Wolfgang / Halary, Sebastien / Hartkopf, Felix / Hawkins-Zafarnia, Arya / Hazrin-Chong, Nur Hazlin / Helfrich, Eric / Hell, Eva / Henry, Tamera / Hernandez, Samuel / Hernandez, Pilar Lopez / Hess-Homeier, David / Hittle, Lauren E / Hoan, Nghiem Xuan / Holik, Aliaksei / Homma, Chiaki / Hoxie, Irene / Huber, Michael / Humphries, Elizabeth / Hyland, Stephanie / Hässig, Andrea / Häusler, Roland / Hüsser, Nathalie / Petit, Robert A / Iderzorig, Badamnyambuu / Igarashi, Mizuki / Iqbal, Shaikh B / Ishikawa, Shino / Ishizuka, Sakura / Islam, Sharah / Islam, Riham / Ito, Kohei / Ito, Sota / Ito, Takayuki / Ivankovic, Tomislav / Iwashiro, Tomoki / Jackson, Sarah / Jacobs, JoAnn / James, Marisano / Jaubert, Marianne / Jerier, Marie-Laure / Jiminez, Esmeralda / Jinfessa, Ayantu / De Jong, Ymke / Joo, Hyun Woo / Jospin, Guilllaume / Kajita, Takema / Ahmad Kassim, Affifah Saadah / Kato, Nao / Kaur, Amrit / Kaur, Inderjit / de Souza Gomes Kehdy, Fernanda / Khadka, Vedbar S / Khan, Shaira / Khavari, Mahshid / Ki, Michelle / Kim, Gina / Kim, Hyung Jun / Kim, Sangwan / King, Ryan J / KoLoMonaco, Giuseppe / Koag, Ellen / Kobko-Litskevitch, Nadezhda / Korshevniuk, Maryna / Kozhar, Michael / Krebs, Jonas / Kubota, Nanami / Kuklin, Andrii / Kumar, Sheelta S / Kwong, Rachel / Kwong, Lawrence / Lafontaine, Ingrid / Lago, Juliana / Lai, Tsoi Ying / Laine, Elodie / Laiola, Manolo / Lakhneko, Olha / Lamba, Isha / de Lamotte, Gerardo / Lannes, Romain / De Lazzari, Eleonora / Leahy, Madeline / Lee, Hyunjung / Lee, Yunmi / Lee, Lucy / Lemaire, Vincent / Leong, Emily / Lewandowska, Dagmara / Li, Chenhao / Liang, Weijun / Lin, Moses / Lisboa, Priscilla / Litskevitch, Anna / Liu, Eric Minwei / Liu, Tracy / Livia, Mayra Arauco / Lo, Yui Him / Losim, Sonia / Loubens, Manon / Lu, Jennifer / Lykhenko, Olexandr / Lysakova, 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    Cell. 2021 June 24, v. 184, no. 13

    2021  

    Abstract: We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an annotated, geospatial profile of ... ...

    Institution The International MetaSUB Consortium
    Abstract We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an annotated, geospatial profile of microbial strains, functional characteristics, antimicrobial resistance (AMR) markers, and genetic elements, including 10,928 viruses, 1,302 bacteria, 2 archaea, and 838,532 CRISPR arrays not found in reference databases. We identified 4,246 known species of urban microorganisms and a consistent set of 31 species found in 97% of samples that were distinct from human commensal organisms. Profiles of AMR genes varied widely in type and density across cities. Cities showed distinct microbial taxonomic signatures that were driven by climate and geographic differences. These results constitute a high-resolution global metagenomic atlas that enables discovery of organisms and genes, highlights potential public health and forensic applications, and provides a culture-independent view of AMR burden in cities.
    Keywords Archaea ; antibiotic resistance ; climate ; forensic sciences ; humans ; metagenomics ; microbial ecology ; microbiome ; public health
    Language English
    Dates of publication 2021-0624
    Size p. 3376-3393.e17.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 187009-9
    ISSN 1097-4172 ; 0092-8674
    ISSN (online) 1097-4172
    ISSN 0092-8674
    DOI 10.1016/j.cell.2021.05.002
    Database NAL-Catalogue (AGRICOLA)

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