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  1. AU="Valentini, Laura"
  2. AU="Smith, Mackenzie J"
  3. AU="Ana Maria Murta Santi"
  4. AU="Poloniato, Antonella"
  5. AU="Gramenzi, Annagiulia"
  6. AU="Wang, Li-Feng"
  7. AU="Zhao, Changyu"

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  1. Buch ; Konferenzbeitrag: Consensus Conference on Chiari Malformation

    Valentini, Laura Grazia

    May 7 - 9, 2009 - Milan, Italy

    (Neurological sciences ; 32, Suppl. 3)

    2011  

    Veranstaltung/Kongress Consensus Conference sulla Malformazione di Chiari (2009, Mailand)
    Verfasserangabe [guest ed.: L. Valentini]
    Serientitel Neurological sciences ; 32, Suppl. 3
    Überordnung
    Sprache Englisch
    Umfang A10 S., S. S263 - S356 : Ill., graph. Darst.
    Verlag Springer
    Erscheinungsort Milano
    Erscheinungsland Italien
    Dokumenttyp Buch ; Konferenzbeitrag
    HBZ-ID HT017119698
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  2. Artikel ; Online: Letter to the Editor. Spinal column shortening for secondary TCS.

    Valentini, Laura G / Vetrano, Ignazio G

    Journal of neurosurgery. Pediatrics

    2021  Band 29, Heft 1, Seite(n) 124–125

    Mesh-Begriff(e) Humans ; Lumbar Vertebrae
    Sprache Englisch
    Erscheinungsdatum 2021-10-01
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Letter ; Comment
    ZDB-ID 2403985-8
    ISSN 1933-0715 ; 1933-0707
    ISSN (online) 1933-0715
    ISSN 1933-0707
    DOI 10.3171/2021.6.PEDS21328
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Letter: Posterior Vertebral Column Subtraction Osteotomy for Recurrent Tethered Cord Syndrome: A Multicenter, Retrospective Analysis.

    Vetrano, Ignazio G / Valentini, Laura G

    Neurosurgery

    2021  Band 89, Heft 2, Seite(n) E135–E136

    Mesh-Begriff(e) Humans ; Neural Tube Defects/surgery ; Osteotomy ; Retrospective Studies ; Spinal Nerve Roots ; Spine
    Sprache Englisch
    Erscheinungsdatum 2021-04-20
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1093/neuros/nyab150
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Surgical Management of Chiari 1.5 in Children: A Truly Different Disease?

    Vetrano, Ignazio G / Barbotti, Arianna / Galbiati, Tommaso Francesco / Mariani, Sabrina / Erbetta, Alessandra / Chiapparini, Luisa / Saletti, Veronica / Valentini, Laura G

    Journal of clinical medicine

    2024  Band 13, Heft 6

    Abstract: Background: ...

    Abstract Background:
    Sprache Englisch
    Erscheinungsdatum 2024-03-15
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13061708
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Comparison between clinical evaluations and laboratory findings and the impact of biofilm on antimicrobial susceptibility in vitro in canine otitis externa.

    Luciani, Luca / Stefanetti, Valentina / Rampacci, Elisa / Gobbi, Pietro / Valentini, Laura / Capuozzo, Raffaella / Passamonti, Fabrizio

    Veterinary dermatology

    2023  Band 34, Heft 6, Seite(n) 586–596

    Abstract: Background: In canine otitis externa (OE), biofilm-producing bacteria are frequently present but biofilm may be underdiagnosed clinically.: Hypothesis/objectives: The study aimed to investigate an association between clinical and cytological findings ...

    Abstract Background: In canine otitis externa (OE), biofilm-producing bacteria are frequently present but biofilm may be underdiagnosed clinically.
    Hypothesis/objectives: The study aimed to investigate an association between clinical and cytological findings with bacteriological data from dogs with OE, to establish, through Environmental Scanning Electron Microscope (ESEM) examination, whether the presence of biofilm in vivo can be predicted and to evaluate the impact of biofilm on antimicrobial susceptibility tests.
    Materials and methods: Fifty-six dogs showing clinical signs of OE were enrolled. One cotton swab each was collected for ESEM, bacterial culture and susceptibility testing and for cytology. Staphylococcus pseudintermedius (n = 42, 48.8%) and Pseudomonas aeruginosa (n = 26, 30.2%) were tested for their ability to form biofilm. Minimum Inhibitory Concentrations (MIC), Minimal Biofilm Inhibitory Concentrations (MBIC) and Minimal Biofilm Eradication Concentrations (MBEC) towards enrofloxacin, gentamicin, polymyxin B and rifampicin were determined.
    Results: Pseudomonas aeruginosa was positively associated with the biofilm clinical evaluation (p < 0.01) and neutrophils (p < 0.05), nuclear streaks (p < 0.01) and rods bacteria (p < 0.01) on cytology. S. pseudintermedius was associated with a low presence of neutrophils. There was a statistical correlation between clinical and cytological biofilm presence (p ≤ 0.01), but none with the biofilm production assay nor ESEM biofilm detection. No differences were found comparing the results of MIC and MBIC. MBEC results showed higher values than MIC and MBIC for all antimicrobials tested (p ≤ 0.001).
    Conclusions and clinical relevance: Biofilm presence in OE was often underdiagnosed. Even if there is no specific clinical or cytological pattern related to biofilm, its presence should always be suspected.
    Mesh-Begriff(e) Dogs ; Animals ; Otitis Externa/drug therapy ; Otitis Externa/veterinary ; Otitis Externa/microbiology ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Anti-Infective Agents/pharmacology ; Biofilms ; Microbial Sensitivity Tests/veterinary ; Dog Diseases/drug therapy ; Dog Diseases/microbiology
    Chemische Substanzen Anti-Bacterial Agents ; methyl 2-(-5-fluoro-2-hydroxyphenyl)-1 H-benzo(d)imidazole-5-carboxylate ; Anti-Infective Agents
    Sprache Englisch
    Erscheinungsdatum 2023-08-14
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2011122-8
    ISSN 1365-3164 ; 0959-4493
    ISSN (online) 1365-3164
    ISSN 0959-4493
    DOI 10.1111/vde.13197
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: The in vitro cytotoxic effects of natural (fibrous epsomite crystals) and synthetic (Epsom salt) magnesium sulfate.

    Salucci, Sara / Giordani, Matteo / Betti, Michele / Valentini, Laura / Gobbi, Pietro / Mattioli, Michele

    Microscopy research and technique

    2023  Band 87, Heft 4, Seite(n) 685–694

    Abstract: Exposure to mineral fibers represents an occupational and environmental hazard since particulate inhalation leads to several health disorders. However, few data are available on the effect of fibers with high solubility like natural epsomite, a water- ... ...

    Abstract Exposure to mineral fibers represents an occupational and environmental hazard since particulate inhalation leads to several health disorders. However, few data are available on the effect of fibers with high solubility like natural epsomite, a water-soluble fiber with an inhalable size that allows it to penetrate biological systems, with regard to the respiratory tract. This study evaluated the natural (fibrous epsomite) and synthetic (Epsom salt) magnesium sulfate pathogenicity. Investigations have been performed through morpho-functional and biochemical analyses, in an in vitro cell model that usually grows as monocytes, but that under appropriate conditions differentiates into macrophages. These latter, known as alveolar macrophages, if referred to lungs, represent the first line of defense against harmful inhaled stimuli. Morphological observations reveal that, if Epsom salt induces osmotic stress on cell culture, natural epsomite fibers lead to cellular alterations including thickening of the nuclear envelope and degenerated mitochondria. Moreover, the insoluble fraction (impurities) internalized by cells induces diffuse damage characterized at the highest dosage and exposure time by secondary necrosis or necrotic cell death features. Biochemical analyses confirm this mineral behavior that involves MAPK pathway activation, resulting in many different cellular responses ranging from proliferation control to cell death. Epsom salt leads to MAPK/ERK activation, a marker predictive of overall survival. Unlike, natural epsomite induces upregulation of MAPK/p38 protein involved in the phosphorylation of downstream targets driving necrotic cell death. These findings demonstrate natural epsomite toxicity on U937 cell culture, making the inhalation of these fibers potentially hazardous for human health. RESEARCH HIGHLIGHTS: Natural epsomite and synthetic Epsom salt effects have been evaluated in U937 cell model. Epsom salt induces an osmotic cellular stress. Natural epsomite fibers lead to cellular damage and can be considered potentially dangerous for human health.
    Mesh-Begriff(e) Humans ; Magnesium Sulfate/pharmacology ; U937 Cells ; Antineoplastic Agents ; Cell Culture Techniques ; Macrophages
    Chemische Substanzen Magnesium Sulfate (7487-88-9) ; Antineoplastic Agents
    Sprache Englisch
    Erscheinungsdatum 2023-11-19
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1099714-3
    ISSN 1097-0029 ; 1059-910X
    ISSN (online) 1097-0029
    ISSN 1059-910X
    DOI 10.1002/jemt.24458
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: A Multidisciplinary Approach in Examining the Susceptibility to Microbial Attack of Polyacrylic and Polyurethane Resins Used in Art Restoration.

    Campana, Raffaella / Sabatini, Luigia / Giorgi, Luca / Pettinari, Giulia / Valentini, Laura / Gobbi, Pietro

    International journal of molecular sciences

    2022  Band 23, Heft 19

    Abstract: The synthetic polymers used to protect artworks from deterioration process can be colonized by the fungi and bacteria responsible for the biodeterioration process. In this study, the susceptibility of synthetic polyacrylics and polyurethane resins to ... ...

    Abstract The synthetic polymers used to protect artworks from deterioration process can be colonized by the fungi and bacteria responsible for the biodeterioration process. In this study, the susceptibility of synthetic polyacrylics and polyurethane resins to microorganisms (
    Mesh-Begriff(e) Bacteria ; Disinfectants ; Esters ; Fungi ; Penicillium ; Polymers ; Polyurethanes/pharmacology
    Chemische Substanzen Disinfectants ; Esters ; Polymers ; Polyurethanes
    Sprache Englisch
    Erscheinungsdatum 2022-10-03
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms231911725
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Morphological analysis of the seeds of three pseudocereals by using light microscopy and ESEM-EDS.

    Ninfali, Paolino / Panato, Anna / Bortolotti, Federica / Valentini, Laura / Gobbi, Pietro

    European journal of histochemistry : EJH

    2020  Band 64, Heft 1

    Abstract: The seed morphology of three Pseudocereal Grains (PSCg), i.e. quinoa (Chenopodium quinoa Willd, Chenopodiaceae), buckwheat (Fagopyrum esculentum Moench, Polygonaceae) and amaranth (Amaranthus caudatus L., Amaranthaceae) was studied by light microscopy ( ... ...

    Abstract The seed morphology of three Pseudocereal Grains (PSCg), i.e. quinoa (Chenopodium quinoa Willd, Chenopodiaceae), buckwheat (Fagopyrum esculentum Moench, Polygonaceae) and amaranth (Amaranthus caudatus L., Amaranthaceae) was studied by light microscopy (LM) and Environmental Scanning Electron Microscopy coupled with Energy Dispersive Spectroscopy (ESEM-EDS). LM was used with visible light to evaluate either unstained sections or sections stained with Azan mixture and with fluorescent light. The aim of the study was to compare the architecture of the three seeds in order to connect their morphology with nutrient localization. The Azan staining allowed for the visualization of the seed coat, the embryo - with its shoot apical meristem - and the radicle cell layers, whereas the use of fluorescent microscopy identified the cells rich in phenolic compounds. Finally, the ESEM-EDS analysis revealed that the seed coat of the quinoa was thinner than that of amaranth or buckwheat. In all PSCg, starch granules appeared to be located in large polygonal cells, surrounded by a thin cell wall. Several globoids of proteins were observed in the embryo cells. In the radicle section, the vascular bundles of the procambium were evident, while Amaranth only showed a consistent layer of calcium crystals, located between the embryo and the perysperm. The morphological differences of the three PSCg were discussed in the context of their structural resistance to processing technologies which impact on nutritional value of derived foods.
    Mesh-Begriff(e) Amaranthus/anatomy & histology ; Amaranthus/embryology ; Chenopodium quinoa/anatomy & histology ; Chenopodium quinoa/embryology ; Edible Grain/anatomy & histology ; Edible Grain/embryology ; Fagopyrum/anatomy & histology ; Fagopyrum/embryology ; Microscopy, Electron, Scanning ; Microscopy, Fluorescence ; Seeds/anatomy & histology ; Seeds/embryology
    Sprache Englisch
    Erscheinungsdatum 2020-01-10
    Erscheinungsland Italy
    Dokumenttyp Journal Article
    ZDB-ID 1109511-8
    ISSN 2038-8306 ; 0391-7258 ; 1121-4201 ; 1121-760X
    ISSN (online) 2038-8306
    ISSN 0391-7258 ; 1121-4201 ; 1121-760X
    DOI 10.4081/ejh.2020.3075
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Innovative scanning electron microscopic investigation in blood samples of patients affected by leukaemia: A physical-chemical-biological approach.

    Gatti, Antonietta / Manti, Anita / Valentini, Laura / Rocchi, Marco Bruno Luigi / Montanari, Stefano

    Micron (Oxford, England : 1993)

    2021  Band 144, Seite(n) 103037

    Abstract: The study proposes an innovative, interdisciplinary observation on blood samples of patients coming from the region Marche (Italy) suffering from acute myeloid leukaemia (AML) by means of a scanning electron microscope coupled with an X-ray microprobe of ...

    Abstract The study proposes an innovative, interdisciplinary observation on blood samples of patients coming from the region Marche (Italy) suffering from acute myeloid leukaemia (AML) by means of a scanning electron microscope coupled with an X-ray microprobe of an Energy Dispersive Spectroscope. A novel protocol of blood preparation was studied and prepared to identify exogenous, potentially toxic foreign bodies coming from an environmental contamination. The results on the four different blood fractions of 38 blood samples (erythrocytes, leukocytes, platelets, and plasma) indicate that the circulating blood of leukaemic patients shows the systematic presence of physical contaminants, with a frequency and concentration which are statistically meaningful as compared to the healthy controls. The chemical compositions of the particles were identified as well as the frequency of the elements they were composed of. The analysis of these chemical compositions demonstrated that these patients had undergone a remarkable environmental, occupational, industrial exposure at some time. A possible pathological mechanism based on a nano-bio-interaction between the internalized environmental particulate matter and the blood components is hypothesized and discussed.
    Mesh-Begriff(e) Adult ; Aged ; Environmental Exposure ; Environmental Pollutants/blood ; Humans ; Leukemia, Myeloid, Acute/blood ; Microscopy, Electron, Scanning/methods ; Middle Aged ; Nanoparticles/analysis ; Nanoparticles/chemistry ; Particulate Matter/blood ; Spectrometry, X-Ray Emission/methods
    Chemische Substanzen Environmental Pollutants ; Particulate Matter
    Sprache Englisch
    Erscheinungsdatum 2021-02-19
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 207808-9
    ISSN 1878-4291 ; 0047-7206 ; 0968-4328
    ISSN (online) 1878-4291
    ISSN 0047-7206 ; 0968-4328
    DOI 10.1016/j.micron.2021.103037
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Buch: Justice in a globalized world

    Valentini, Laura

    a normative framework

    2011  

    Verfasserangabe Laura Valentini
    Schlagwörter Cosmopolitanism ; Economic assistance/Philosophy ; Justice (Philosophy) ; Social justice ; Gerechtigkeit ; Verteilungsgerechtigkeit ; Globalisierung ; Welt
    Sprache Englisch
    Umfang VIII, 229 S.
    Verlag Oxford Univ. Press
    Erscheinungsort Oxford u.a.
    Dokumenttyp Buch
    Anmerkung Literaturverz. S. [213] - 222
    ISBN 019959385X ; 9780199593859
    Datenquelle Ehemaliges Sondersammelgebiet Küsten- und Hochseefischerei

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