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  1. Book ; Online: Recent Advances in Nutrition for Disease Prevention and Sports Performance Enhancement

    Valenzuela, Pedro L

    2023  

    Keywords Humanities ; Social interaction ; cardiovascular health ; cardiovascular disease ; aging ; sarcopenia ; microbiota ; physical performance ; sports ; exercise physiology ; muscle damage ; ergogenic ; supplements
    Language English
    Size 1 electronic resource (200 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030377785
    ISBN 9783036577036 ; 3036577033
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Recent Advances in Nutrition for Disease Prevention and Sports Performance Enhancement.

    Valenzuela, Pedro L

    Nutrients

    2023  Volume 15, Issue 5

    Abstract: The important role of nutrition on both health and sports performance, and particularly its joint association with physical exercise, is becoming increasingly clear in recent years [ ... ]. ...

    Abstract The important role of nutrition on both health and sports performance, and particularly its joint association with physical exercise, is becoming increasingly clear in recent years [...].
    MeSH term(s) Nutritional Status ; Athletic Performance ; Exercise
    Language English
    Publishing date 2023-02-26
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15051170
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Physical Activity and Cognitive Performance in Early Childhood: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    Morales, Javier S / Alberquilla Del Río, Eva / Valenzuela, Pedro L / Martínez-de-Quel, Óscar

    Sports medicine (Auckland, N.Z.)

    2024  

    Abstract: Background: Growing evidence suggests that physical activity (PA) could improve cognitive performance in youths, but whether these effects occur from early childhood remains unclear.: Objective: To summarize evidence on the effects of PA ... ...

    Abstract Background: Growing evidence suggests that physical activity (PA) could improve cognitive performance in youths, but whether these effects occur from early childhood remains unclear.
    Objective: To summarize evidence on the effects of PA interventions on cognitive performance in early childhood.
    Methods: We performed a systematic search in PubMed, Scopus, Web of Science and PsycINFO (from inception to 6 September 2023) for randomized controlled trials assessing the effects of PA interventions (≥ 3 weeks) on cognitive-related outcomes in early childhood (3-6 years). We conducted a random-effects meta-analysis when five or more studies assessed a given outcome. The potential moderating role of participant (e.g., age) and intervention characteristics (e.g., duration, volume, intensity, cognitive engagement) was also assessed.
    Results: We found a total of 24 studies (N = 3483 children) that were deemed to be of overall fair methodological quality. PA interventions were supervised and lasted between 3 and 24 weeks. The most common session duration was 30 min, with a frequency of two sessions per week. Pooled analyses revealed that PA interventions have positive effects on all analysed outcomes, including attention (standardized mean difference (SMD) = 0.49, 95% confidence interval (CI) 0.18-0.79, p = 0.002), inhibition (SMD = 0.45, 95% CI 0.06-0.84, p = 0.022), working memory (SMD = 0.50, 95% CI 0.18-0.82, p = 0.002), cognitive flexibility (SMD = 0.39, 0.15-0.62, p = 0.002) and vocabulary (SMD = 1.18, 0.19-2.16, p = 0.019). Sensitivity analyses confirmed the benefits in all cases except for inhibition (p = 0.062). No consistent differences were found relating to any moderator variable.
    Conclusions: Although further research is warranted, our findings suggest that PA interventions may improve cognitive performance in early childhood, particularly in the domains of attention, inhibition, working memory, cognitive flexibility and vocabulary. These findings might support the implementation of PA interventions from early childhood.
    Prospero registration: CRD42021249319.
    Language English
    Publishing date 2024-04-10
    Publishing country New Zealand
    Document type Systematic Review
    ZDB-ID 605911-9
    ISSN 1179-2035 ; 0112-1642
    ISSN (online) 1179-2035
    ISSN 0112-1642
    DOI 10.1007/s40279-024-02020-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Physical exercise: a polypill against chronic kidney disease.

    Valenzuela, Pedro L / Castillo-García, Adrián / Saco-Ledo, Gonzalo / Santos-Lozano, Alejandro / Lucia, Alejandro

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2024  

    Abstract: We are currently facing a pandemic of physical inactivity that might contribute to the growing prevalence of chronic kidney disease (CKD). Here, we summarize currently available evidence on the association between physical activity and CKD, and also ... ...

    Abstract We are currently facing a pandemic of physical inactivity that might contribute to the growing prevalence of chronic kidney disease (CKD). Here, we summarize currently available evidence on the association between physical activity and CKD, and also review the effects of exercise intervention in affected patients. Physical activity/exercise might act as a polypill against CKD, preventing its development or even exerting beneficial effects once it is established (i.e. improvements in patients' physical fitness and cardiovascular risk, as well as in kidney function). Exercise benefits are also found at advanced CKD stages or in patients under hemodialysis. The biological mechanisms behind the clinical evidence are also discussed. An active lifestyle appears as a cornerstone in CKD prevention and management.
    Language English
    Publishing date 2024-03-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfae062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Exerkine response to acute exercise: Still much to discover.

    Valenzuela, Pedro L / Rivas-Baeza, Beatriz / Fiuza-Luces, Carmen / Lucia, Alejandro

    Journal of sport and health science

    2024  

    Language English
    Publishing date 2024-04-12
    Publishing country China
    Document type Journal Article
    ZDB-ID 2673028-5
    ISSN 2213-2961 ; 2095-2546
    ISSN (online) 2213-2961
    ISSN 2095-2546
    DOI 10.1016/j.jshs.2024.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Exercise benefits meet the esophagus.

    Santos-Lozano, Alejandro / Valenzuela, Pedro L / Fiuza-Luces, Carmen / Lucia, Alejandro

    Journal of sport and health science

    2024  

    Language English
    Publishing date 2024-04-02
    Publishing country China
    Document type Journal Article
    ZDB-ID 2673028-5
    ISSN 2213-2961 ; 2095-2546
    ISSN (online) 2213-2961
    ISSN 2095-2546
    DOI 10.1016/j.jshs.2024.04.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Supervised Versus Unsupervised Exercise for the Improvement of Physical Function and Well-Being Outcomes in Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

    Gómez-Redondo, Paola / Valenzuela, Pedro L / Morales, Javier S / Ara, Ignacio / Mañas, Asier

    Sports medicine (Auckland, N.Z.)

    2024  

    Abstract: Background: Unsupervised exercise intervention (UNSUP) appears to be a practical and beneficial strategy for older adults, although its feasibility and effectiveness compared to supervised exercise intervention (SUP) remains unknown. We aimed to compare ...

    Abstract Background: Unsupervised exercise intervention (UNSUP) appears to be a practical and beneficial strategy for older adults, although its feasibility and effectiveness compared to supervised exercise intervention (SUP) remains unknown. We aimed to compare the safety, attendance/adherence rates, and effectiveness of SUP versus UNSUP on physical function and well-being outcomes in older adults.
    Methods: A systematic search was conducted in PubMed, Web of Science, CINAHL, SPORTDiscus, and APA PsycINFO up to September 2022 for randomized controlled trials comparing SUP versus UNSUP in older adults (≥ 60 years). Safety and attendance/adherence rates were registered as indicators of feasibility, and meta-analyses were performed for physical function and well-being outcomes. Sub-analyses were performed for those studies that applied a similar intervention in both groups and for those studies where participants performed ≥ 66% of the sessions in the assigned condition.
    Results: Thirty-four studies were included (n = 2830). No serious adverse events were reported, with similar attendance rates (81%) for both SUP and UNSUP. Compared with UNSUP, SUP induced significant higher benefits on knee extension strength (standardized mean difference (SMD) = 0.18, p = 0.002), sit-to-stand test (STS, SMD = 0.25, p = 0.050), timed-up-and-go test (TUG, SMD = 0.21, p = 0.035), usual gait speed (SMD = 0.29, p = 0.026), lean mass (mean difference = 1.05 kg, p < 0.001) and health-related quality of life (HRQoL, SMD = 0.21, p = 0.035), albeit only knee extension strength remained significant in sensitivity analyses. Sub-analyses revealed superior benefits of SUP on knee extension strength when only considering those studies that applied a similar intervention in both SUP and UNSUP groups. However, no significant benefits were found for the remaining outcomes. Beneficial effects of SUP over UNSUP were also observed for knee extension strength, STS, functional reach test, TUG, usual gait speed, lean mass, and HRQoL when separately analyzing those studies in which participants performed ≥ 66% of the sessions in the assigned condition.
    Conclusions: Current evidence suggests that both SUP and UNSUP programs are safe and could exert benefits on physical function and HRQoL. However, despite being associated with similar attendance rates, SUP might offer some additional benefits, although further high-quality research (i.e., accounting for confounding factors such as presence of supervised sessions in UNSUP or vice versa, as well as equating the exercise dose) is necessary to confirm these findings.
    Prospero registration number: CRD42022326420.
    Language English
    Publishing date 2024-04-22
    Publishing country New Zealand
    Document type Systematic Review
    ZDB-ID 605911-9
    ISSN 1179-2035 ; 0112-1642
    ISSN (online) 1179-2035
    ISSN 0112-1642
    DOI 10.1007/s40279-024-02024-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Influence of Preterm Birth and Low Birthweight on Physical Fitness: A Systematic Review, Meta-Analysis, and Meta-Regression.

    Martínez-Zamora, Marcos D / Martín-Martínez, Carlos / Martínez-de-Quel, Óscar / Valenzuela, Pedro L

    Sports medicine (Auckland, N.Z.)

    2024  

    Abstract: Background: Preterm birth and low birthweight (LBW) might be associated with reduced physical fitness, although evidence remains inconclusive.: Objective: To examine the influence of preterm birth and LBW on physical fitness, as well as to assess ... ...

    Abstract Background: Preterm birth and low birthweight (LBW) might be associated with reduced physical fitness, although evidence remains inconclusive.
    Objective: To examine the influence of preterm birth and LBW on physical fitness, as well as to assess whether variables such as gestational age, birthweight, or age at assessment moderate these effects.
    Methods: PubMed, Scopus, and PsycINFO were systematically searched from inception to 7 December 2023 for case-control and cohort studies analyzing the association between preterm birth or LBW (or gestational age or birthweight as continuous variables) with at least one physical fitness-related outcome (i.e., cardiorespiratory fitness (CRF), muscle strength, flexibility, speed, agility). Random-effects meta-analysis and meta-regression models were used to estimate the pooled effect size, as well as to examine potential associations between the magnitude of the effect and gestational age, birthweight, or age at assessment.
    Results: Fifty-two studies (n = 920,603 participants, average age ranging from 4.7 to 34.4 years) were included. Preterm birth was associated with reduced CRF (standardized mean difference (SMD) = -0.38, 95% confidence interval (CI) = -0.51 to -0.25) and muscle strength (SMD = -0.44, 95% CI = -0.79 to -0.08). LBW was associated with reduced CRF (SMD = -0.40, 95% CI = -0.64 to -0.17), muscle strength (SMD = -0.18, 95% CI = -0.24 to -0.13), flexibility (SMD = -0.11, 95% CI = -0.22 to -0.01), and agility (SMD = -0.99, 95% CI = -1.91 to -0.07). Meta-regression analyses showed that a lower gestational age or birthweight were associated with larger reductions in physical fitness, whereas no consistent association was found for the age at assessment.
    Conclusion: Both preterm birth and LBW seem associated with reduced physical fitness regardless of age, with larger reductions overall observed in individuals with lower gestational age or birthweight. These findings might support the implementation of preventive strategies (e.g., fitness monitoring and physical exercise interventions) in these populations through the life course. PROSPERO registration: CRD42021231845.
    Language English
    Publishing date 2024-05-06
    Publishing country New Zealand
    Document type Systematic Review
    ZDB-ID 605911-9
    ISSN 1179-2035 ; 0112-1642
    ISSN (online) 1179-2035
    ISSN 0112-1642
    DOI 10.1007/s40279-024-02026-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: What Does It Take to Become a Professional Cyclist? A Laboratory-Based Longitudinal Analysis in Competitive Young Riders.

    Valenzuela, Pedro L / Alejo, Lidia B / Lucia, Alejandro / Barranco-Gil, David

    International journal of sports physiology and performance

    2023  Volume 18, Issue 11, Page(s) 1275–1282

    Abstract: Purpose: Laboratory-based indicators are commonly used for performance assessment in young cyclists. However, evidence supporting the use of these indicators mostly comes from cross-sectional research, and their validity as predictors of potential ... ...

    Abstract Purpose: Laboratory-based indicators are commonly used for performance assessment in young cyclists. However, evidence supporting the use of these indicators mostly comes from cross-sectional research, and their validity as predictors of potential future performance remains unclear. We aimed to assess the role of laboratory variables for predicting transition from U23 (under 23 y) to professional category in young cyclists.
    Methods: Sixty-five U23 male road cyclists (19.6 [1.5] y) were studied. Endurance (maximal graded test and simulated 8-min time trial [TT]), muscle strength/power (squat, lunge, and hip thrust), and body composition (assessed with dual-energy X-ray absorptiometry) indicators were determined. Participants were subsequently followed and categorized attending to whether they had transitioned ("Pro") or not ("Non-Pro") to the professional category during the study period.
    Results: The median follow-up period was 3 years. Pro cyclists (n = 16) showed significantly higher values than Non-Pro riders (n = 49) for ventilatory thresholds, peak power output, peak oxygen uptake, and TT performance (all P < .05, effect size > 0.69) and lower levels of fat mass and bone mineral content/density (P < .05, effect size > 0.63). However, no significant differences were found for muscle strength/power indicators (P > .05, effect size < 49). The most accurate individual predictor was TT performance (overall predictive value = 76% for a cutoff value of 5.6 W·kg-1). However, some variables that did not reach statistical significance in univariate analyses contributed significantly to a multivariate model (R2 = .79, overall predictive value = 94%).
    Conclusions: Although different "classic" laboratory-based endurance indicators can predict the potential of reaching the professional category in U23 cyclists, a practical indicator such as 8-minute TT performance showed the highest prediction accuracy.
    MeSH term(s) Humans ; Male ; Cross-Sectional Studies ; Body Composition ; Muscle Strength ; Bone Density ; Absorptiometry, Photon ; Bicycling/physiology ; Oxygen Consumption
    Language English
    Publishing date 2023-08-23
    Publishing country United States
    Document type Journal Article
    ISSN 1555-0273
    ISSN (online) 1555-0273
    DOI 10.1123/ijspp.2023-0083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Calorie Restriction with or without Time-Restricted Eating in Weight Loss.

    Valenzuela, Pedro L / Castillo-García, Adrián / Lucia, Alejandro

    The New England journal of medicine

    2022  Volume 387, Issue 3, Page(s) 280–281

    MeSH term(s) Caloric Restriction ; Diet, Reducing ; Humans ; Weight Loss
    Language English
    Publishing date 2022-07-13
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2207023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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