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  1. Book: Thoracic tumors

    Lokuhetty, Dilani / White, Valeri A. / Cree, Ian A.

    (WHO Classification of Tumours ; 5)

    2021  

    Institution WHO / Classification of Tumours Editorial Board
    International Agency for Research on Cancer
    International Association for the Study of Lung Cancer
    ITMIG
    International Mesothelioma Panel
    Author's details edited by the WHO Classification of Tumours Editorial Board ; Dilani Lokuhetty, Valeri A. White, Ian A. Cree
    Series title WHO Classification of Tumours ; 5
    World Health Organization classification of tumours
    Collection World Health Organization classification of tumours
    Keywords Thoracic Neoplasms
    Language English
    Size XIII, 565 Seiten, Illustrationen (farbig)
    Edition [5. Auflage]
    Publisher International Agency for Research on Cancer, World Health Organization
    Publishing place Lyon Cedex
    Publishing country France
    Document type Book
    HBZ-ID HT020938359
    ISBN 978-92-832-4506-3 ; 92-832-4506-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2021 A 753 on loan 0 Vormerkungen

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  2. Article ; Online: COVID-19 and ESRD: Entering a New Era of Uncertainty.

    Valeri, Anthony

    Kidney international reports

    2020  Volume 5, Issue 9, Page(s) 1381–1382

    Keywords covid19
    Language English
    Publishing date 2020-07-25
    Publishing country United States
    Document type Editorial ; Comment
    ISSN 2468-0249
    ISSN (online) 2468-0249
    DOI 10.1016/j.ekir.2020.07.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Vitamin Supplementation in ESKD: Too Little or Too Much of a Good Thing?

    Valeri, Anthony

    Kidney international reports

    2020  Volume 5, Issue 12, Page(s) 2125–2126

    Language English
    Publishing date 2020-09-28
    Publishing country United States
    Document type Editorial ; Comment
    ISSN 2468-0249
    ISSN (online) 2468-0249
    DOI 10.1016/j.ekir.2020.09.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: State of the Art and Future of Stem Cell Therapy in Ischemic Stroke: Why Don't We Focus on Their Administration?

    Valeri, Andrea / Mazzon, Emanuela

    Bioengineering (Basel, Switzerland)

    2023  Volume 10, Issue 1

    Abstract: Stroke is one of the leading causes of death and disability worldwide, so there is an urgent need to find a therapy for the tragic outcomes of this cerebrovascular disease. Stem cells appeared to be a good solution for many conditions, so different ... ...

    Abstract Stroke is one of the leading causes of death and disability worldwide, so there is an urgent need to find a therapy for the tragic outcomes of this cerebrovascular disease. Stem cells appeared to be a good solution for many conditions, so different experiments were made to establish stem cells as a feasible therapy for stroke. The aim of this review is to analyze the state of the art of stem cell therapy for stroke and if the route of administration could represent a valid adjusting point for ameliorating the therapy's outcome. To obtain this, we searched the scientific literature of the last 10 years for relevant in vitro and in vivo evidence regarding stem cells' potential in stroke therapy. In vitro evidence points to hypoxia, among the preconditioning strategies, as the most used and probably efficient method to enhance cells qualities, while in vivo results raise the question if it is the type of cells or how they are administrated which can make the difference in terms of efficiency. Unfortunately, despite the number of clinical trials, only a few were successfully concluded, demonstrating how urgent the necessity is to translate pre-clinical results into clinics. Since any type of stem cell seems suitable for therapy, the chosen route of administration corresponds to different engraftment rates, distribution and efficiency in terms of the beneficial effects of stem cells. Intravenous administration was widely used for delivering stem cells into the human body, but recently intranasal administration has given promising results in vivo. It allows stem cells to efficiently reach the brain that was precluded to intravenous administration, so it is worth further investigation.
    Language English
    Publishing date 2023-01-14
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering10010118
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Research on texture images and radiomics in urology: a review of urological MR imaging applications.

    Valeri, Antoine / Nguyen, Truong An

    Current opinion in urology

    2023  Volume 33, Issue 6, Page(s) 428–436

    Abstract: Purpose of review: Tumor volume and heterogenicity are associated with diagnosis and prognosis of urological cancers, and assessed by conventional imaging. Quantitative imaging, Radiomics, using advanced mathematical analysis may contain information ... ...

    Abstract Purpose of review: Tumor volume and heterogenicity are associated with diagnosis and prognosis of urological cancers, and assessed by conventional imaging. Quantitative imaging, Radiomics, using advanced mathematical analysis may contain information imperceptible to the human eye, and may identify imaging-based biomarkers, a new field of research for individualized medicine. This review summarizes the recent literature on radiomics in kidney and prostate cancers and the future perspectives.
    Recent findings: Radiomics studies have been developed and showed promising results in diagnosis, in characterization, prognosis, treatment planning and recurrence prediction in kidney tumors and prostate cancer, but its use in guiding clinical decision-making remains limited at present due to several limitations including lack of external validations in most studies, lack of prospective studies and technical standardization.
    Summary: Future challenges, besides developing prospective and validated studies, include automated segmentation using artificial intelligence deep learning networks and hybrid radiomics integrating clinical data, combining imaging modalities and genomic features. It is anticipated that these improvements may allow identify these noninvasive, imaging-based biomarkers, to enhance precise diagnosis, improve decision-making and guide tailored treatment.
    MeSH term(s) Humans ; Artificial Intelligence ; Urology ; Prospective Studies ; Magnetic Resonance Imaging ; Biomarkers
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-09-18
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1091792-5
    ISSN 1473-6586 ; 0963-0643
    ISSN (online) 1473-6586
    ISSN 0963-0643
    DOI 10.1097/MOU.0000000000001131
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3345: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: COVID-19 and ESRD

    Valeri, Anthony

    Kidney International Reports

    Entering a New Era of Uncertainty

    2020  Volume 5, Issue 9, Page(s) 1381–1382

    Keywords Nephrology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2468-0249
    DOI 10.1016/j.ekir.2020.07.020
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  8. Article ; Online: Cannabinoids and Neurogenesis: The Promised Solution for Neurodegeneration?

    Valeri, Andrea / Mazzon, Emanuela

    Molecules (Basel, Switzerland)

    2021  Volume 26, Issue 20

    Abstract: The concept of neurons as irreplaceable cells does not hold true today. Experiments and evidence of neurogenesis, also, in the adult brain give hope that some compounds or drugs can enhance this process, helping to reverse the outcomes of diseases or ... ...

    Abstract The concept of neurons as irreplaceable cells does not hold true today. Experiments and evidence of neurogenesis, also, in the adult brain give hope that some compounds or drugs can enhance this process, helping to reverse the outcomes of diseases or traumas that once were thought to be everlasting. Cannabinoids, both from natural and artificial origins, already proved to have several beneficial effects (e.g., anti-inflammatory, anti-oxidants and analgesic action), but also capacity to increase neuronal population, by replacing the cells that were lost and/or regenerate a damaged nerve cell. Neurogenesis is a process which is not highly represented in literature as neuroprotection, though it is as important as prevention of nervous system damage, because it can represent a possible solution when neuronal death is already present, such as in neurodegenerative diseases. The aim of this review is to resume the experimental evidence of phyto- and synthetic cannabinoids effects on neurogenesis, both in vitro and in vivo, in order to elucidate if they possess also neurogenetic and neurorepairing properties.
    MeSH term(s) Animals ; Brain/drug effects ; Cannabinoids/pharmacology ; Humans ; Neurodegenerative Diseases/drug therapy ; Neurogenesis/drug effects ; Neurons/drug effects ; Neuroprotection/drug effects ; Neuroprotective Agents/pharmacology
    Chemical Substances Cannabinoids ; Neuroprotective Agents
    Language English
    Publishing date 2021-10-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules26206313
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 81: Show issues

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  9. Article: Direct comparison between Grade Group assessed on systematic and MRI/ultrasound fusion targeted biopsies correlated to the radical prostatectomy specimens in patients with prostate cancer.

    Payrard-Starck, C / Fourcade, A / An Nguyen, T / Tissot, V / Doucet, L / Marolleau, J / Lucas, C / Fournier, G / Valeri, A

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

    2023  Volume 33, Issue 5, Page(s) 265–271

    Abstract: Objectives: To compare the correlation of Gleason score (GS) and ISUP grade determined by prostate biopsies (PBx) and radical prostatectomy (RP) specimens according to the biopsy technique: ultrasound randomised (RBx) vs. MRI/ultrasound fusion targeted ( ...

    Abstract Objectives: To compare the correlation of Gleason score (GS) and ISUP grade determined by prostate biopsies (PBx) and radical prostatectomy (RP) specimens according to the biopsy technique: ultrasound randomised (RBx) vs. MRI/ultrasound fusion targeted (TBx).
    Materials and methods: Between March 2013 and June 2018, we retrospectively included patients who underwent RP for prostate cancer (PCa) histopathologically proven by RBx and/or TBx. All patients had a prebiopsy MRI by a single radiologist (using PI-RADS score), then transrectal RBx (12cores, blinded to MRI lesions) and TBx (2-4 cores/target) with elastic MRI/ultrasound fusion (UroStation™, Koelis, Grenoble, France). Histological findings were compared: PBx vs. RP.
    Results: One hundred and four patients underwent RP after RBx and/or TBx. ISUP concordance rate was better with the association RBx+TBx 49% (51/104) vs. 43.3% with TBx (P=0.07) and 43.3% with RBx (P=0.13). With RBx, 50% of the patients were downgraded (52/104) against 42.3% (44/104) with TBx (P=0.088). The association RBx+TBx significantly decreased the rate of downgrading of the ISUP score compared to the ISUP score of RP 35.6% (37/104) vs. RBx (50%, P=0.0001) and vs. TBx (42.3%, P=0.016).
    Conclusion: In half of cases, the ISUP score was underestimated in RBx compared to RP specimens. Adding TBx to RBx significantly reduced downgrading. The combination of both biopsy techniques appeared to be the best protocol to get closer to ISUP score and GS of the RP specimens.
    Level of evidence: C.
    MeSH term(s) Humans ; Male ; Image-Guided Biopsy/methods ; Magnetic Resonance Imaging/methods ; Neoplasm Grading ; Prostate/diagnostic imaging ; Prostate/surgery ; Prostate/pathology ; Prostatectomy/methods ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/surgery ; Prostatic Neoplasms/pathology ; Retrospective Studies
    Language English
    Publishing date 2023-02-04
    Publishing country France
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1186190-3
    ISSN 1166-7087
    ISSN 1166-7087
    DOI 10.1016/j.purol.2023.01.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3959: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Correlation dimension of high-dimensional and high-definition experimental time series.

    Makarov, Valeri A / Muñoz, Ricardo / Herreras, Oscar / Makarova, Julia

    Chaos (Woodbury, N.Y.)

    2023  Volume 33, Issue 12

    Abstract: The correlation dimension (CD) is a nonlinear measure of the complexity of invariant sets. First introduced for describing low-dimensional chaotic attractors, it has been later extended to the analysis of experimental electroencephalographic (EEG), ... ...

    Abstract The correlation dimension (CD) is a nonlinear measure of the complexity of invariant sets. First introduced for describing low-dimensional chaotic attractors, it has been later extended to the analysis of experimental electroencephalographic (EEG), magnetoencephalographic (MEG), and local field potential (LFP) recordings. However, its direct application to high-dimensional (dozens of signals) and high-definition (kHz sampling rate) 2HD data revealed a controversy in the results. We show that the need for an exponentially long data sample is the main difficulty in dealing with 2HD data. Then, we provide a novel method for estimating CD that enables orders of magnitude reduction of the required sample size. The approach decomposes raw data into statistically independent components and estimates the CD for each of them separately. In addition, the method allows ongoing insights into the interplay between the complexity of the contributing components, which can be related to different anatomical pathways and brain regions. The latter opens new approaches to a deeper interpretation of experimental data. Finally, we illustrate the method with synthetic data and LFPs recorded in the hippocampus of a rat.
    MeSH term(s) Rats ; Animals ; Time Factors ; Electroencephalography/methods ; Magnetoencephalography ; Brain ; Hippocampus
    Language English
    Publishing date 2023-12-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1472677-4
    ISSN 1089-7682 ; 1054-1500
    ISSN (online) 1089-7682
    ISSN 1054-1500
    DOI 10.1063/5.0168400
    Database MEDical Literature Analysis and Retrieval System OnLINE

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