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  1. Article ; Online: COVID-19 among Chronic Dialysis Patients after First Year of Pandemic, Argentina.

    Vallejos, Augusto / Baldani, Andrea E M / Gauto, Micaela A / Rueda, Dalila V / Santoro, Federico M / Abriata, Graciela

    Emerging infectious diseases

    2022  Volume 28, Issue 11, Page(s) 2294–2297

    Abstract: We performed a descriptive study to characterize effects from COVID-19 among chronic dialysis patients compared with the general population in Argentina during March 2020-February 2021. COVID-19 case-fatality rate of chronic dialysis patients was 10 ... ...

    Abstract We performed a descriptive study to characterize effects from COVID-19 among chronic dialysis patients compared with the general population in Argentina during March 2020-February 2021. COVID-19 case-fatality rate of chronic dialysis patients was 10 times the national rate; the age-standardized mortality ratio was 6.8 (95% CI 6.3-7.3).
    MeSH term(s) Humans ; Pandemics ; COVID-19/epidemiology ; SARS-CoV-2 ; Argentina/epidemiology ; Renal Dialysis
    Language English
    Publishing date 2022-10-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2811.212597
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Unmet Needs of CKD in Latin America: A Review from Expert Virtual Working Group.

    Correa-Rotter, Ricardo / Méndez Durán, Antonio / Vallejos, Augusto / Rico-Fontalvo, Jorge / Cusumano, Ana María / Rosa-Diez, Guillermo Javier / Sánchez Polo, Vicente / Goecke, Helmuth / Arango, José Javier / Cerón, Vanessa Villavicencio / Diná, Eliana / Fonseca, Fabio Hernández / Valdés, Régulo Adolfo / Vanoni, Miguel

    Kidney international reports

    2023  Volume 8, Issue 5, Page(s) 954–967

    Abstract: Chronic kidney disease (CKD) represents a major challenge for Latin American (LatAm) because of its epidemic proportions. Therefore, the current status and knowledge of CKD in Latin America is not clearly understood. Moreover, there is a paucity of ... ...

    Abstract Chronic kidney disease (CKD) represents a major challenge for Latin American (LatAm) because of its epidemic proportions. Therefore, the current status and knowledge of CKD in Latin America is not clearly understood. Moreover, there is a paucity of epidemiologic studies that makes the comparison across the countries even more difficult. To address these gaps, a virtual kidney expert opinion meeting of 14 key opinion leaders from Argentina, Chile, Colombia, Costa Rica, Dominican Republic, Ecuador, Guatemala, Mexico, and Panama was held in January 2022 to review and discuss the status of CKD in various LatAm regions. The meeting discussed the following: (i) epidemiology, diagnosis, and treatment of CKD, (ii) detection and prevention programs, (iii) clinical guidelines, (iv) state of public policies about diagnosis and management of chronic kidney disease, and (v) role of innovative therapies in the management of CKD. The expert panel emphasized that efforts should be made to implement timely detection programs and early evaluation of kidney function parameters to prevent the development or progression of CKD. Furthermore, the panel discussed the importance of raising awareness among health care professionals; disseminating knowledge to the authorities, the medical community, and the general population about the kidney and cardiovascular benefits of novel therapies; and the need for timely updating of clinical practice guidelines, regulatory policies, and protocols across the region.
    Language English
    Publishing date 2023-02-27
    Publishing country United States
    Document type Journal Article
    ISSN 2468-0249
    ISSN (online) 2468-0249
    DOI 10.1016/j.ekir.2023.02.1082
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Dialysis for acute kidney injury associated with influenza a (H1N1) infection.

    Vallejos, Augusto / Arias, Marcelo / Cusumano, Ana / Coste, Eduardo / Simon, Miguel / Martinez, Ricardo / Mendez, Sandra / Raño, Miguel / Sintado, Luis / Lococo, Bruno / Blanco, Carlos / Cestari, Jorge

    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia

    2013  Volume 24, Issue 3, Page(s) 527–533

    Abstract: In June 2009, the World Health Organization declared a novel influenza A, S-OIV (H1N1), pandemic. We observed 44 consecutive patients during the "first wave" of the pandemic. 70.5% of them showed co-morbidities (hypertension, obesity, chronic respiratory ...

    Abstract In June 2009, the World Health Organization declared a novel influenza A, S-OIV (H1N1), pandemic. We observed 44 consecutive patients during the "first wave" of the pandemic. 70.5% of them showed co-morbidities (hypertension, obesity, chronic respiratory diseases, chronic renal disease, diabetes, pregnancy). Serious cases were admitted to the intensive care unit (ICU), particularly those with severe acute respiratory failure. Some of them developed acute kidney injury (AKI) and required renal replacement therapy (RRT). The average time between admission to the ICU and initiation of RRT was 3.16 ± 2.6 days. At initiation of RRT, most patients required mechanical ventilation. No relationship was found with creatinine-kinase levels. Seventy-five percent of the cases were observed during a 3-week period and mortality, related to respiratory failure, doubling of alanine amino transferase and use of inotropics was 81.8%. In conclusion, the H1N1-infected patients who developed RRT-requiring AKI, in the context of multi-organ failure, showed a high mortality rate. Thus, it is mandatory that elaborate strategies aimed at anticipating potential renal complications associated to future pandemics are implemented.
    MeSH term(s) Acute Kidney Injury/diagnosis ; Acute Kidney Injury/epidemiology ; Acute Kidney Injury/mortality ; Acute Kidney Injury/therapy ; Acute Kidney Injury/virology ; Adult ; Argentina/epidemiology ; Chi-Square Distribution ; Comorbidity ; Critical Care ; Female ; Humans ; Influenza A Virus, H1N1 Subtype/pathogenicity ; Influenza, Human/diagnosis ; Influenza, Human/epidemiology ; Influenza, Human/mortality ; Influenza, Human/virology ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Pandemics ; Renal Dialysis/adverse effects ; Renal Dialysis/mortality ; Respiration, Artificial ; Respiratory Insufficiency/epidemiology ; Respiratory Insufficiency/therapy ; Respiratory Insufficiency/virology ; Retrospective Studies ; Risk Factors ; Time Factors ; Time-to-Treatment ; Treatment Outcome ; Young Adult
    Language English
    Publishing date 2013-05-02
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 1379955-1
    ISSN 1319-2442
    ISSN 1319-2442
    DOI 10.4103/1319-2442.111045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Resistive index and chronic allograft nephropathy evaluated in protocol biopsies as predictors of graft outcome.

    Vallejos, Augusto / Alperovich, Gabriela / Moreso, Francesc / Cañas, Concepcion / de Lama, M Eugenia / Gomà, Montserrat / Fulladosa, Xavier / Carrera, Marta / Hueso, Miguel / Grinyó, Josep M / Serón, Daniel

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2005  Volume 20, Issue 11, Page(s) 2511–2516

    Abstract: Introduction: The presence of chronic allograft nephropathy (CAN) in protocol biopsies is negatively associated with graft survival. Although recent studies have indicated that the resistive index (RI) is a predictor of graft failure, it does not ... ...

    Abstract Introduction: The presence of chronic allograft nephropathy (CAN) in protocol biopsies is negatively associated with graft survival. Although recent studies have indicated that the resistive index (RI) is a predictor of graft failure, it does not correlate with CAN in stable grafts. We therefore studied the relationship between RI and CAN and examined the predictive value of both parameters on graft outcome.
    Methods: Included were patients transplanted between 1997 and 2002 and who had protocol biopsies and RI determinations. Renal lesions were blindly evaluated according to Banff 97 criteria. Mean glomerular volume, cortical interstitial volume fraction and intimal arterial volume fraction were estimated using a point counting technique. RI was determined before biopsy in at least two different renal locations. The outcome variable was defined as graft failure or a 30% serum creatinine increase between protocol biopsy and last follow-up.
    Results: Eighty-seven patients were included. RI correlated with recipient age (R = 0.52, P < 0.0001), diastolic blood pressure (R = -0.36, P = 0.0006), pulse pressure index (R = 0.27, P = 0.009) and g-score for histological glomerulitis (rho = 0.30, P = 0.0054), but there were no correlations between RI and chronic Banff scores or any morphometric parameter. The presence of CAN (relative risk, 3.5; 95% confidence interval 1.2-10.2; P = 0.02) but not RI was associated with the outcome variable.
    Conclusion: RI was associated with surrogate measures of vascular compliance such as recipient age and pulse pressure index but not with chronic allograft damage, even when it was evaluated by histomorphometry. Our results indicate that histology may be superior to RI in predicting graft function deterioration, at least in patients with stable renal function.
    MeSH term(s) Adult ; Biopsy, Needle ; Chronic Disease ; Female ; Follow-Up Studies ; Glomerulonephritis/etiology ; Glomerulonephritis/pathology ; Graft Rejection/complications ; Graft Rejection/pathology ; Graft Survival ; Humans ; Kidney Failure, Chronic/therapy ; Kidney Glomerulus/pathology ; Kidney Transplantation ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Risk Factors ; Severity of Illness Index ; Transplantation, Homologous
    Language English
    Publishing date 2005-11
    Publishing country England
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfi041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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