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  1. AU="Vallejos, Humberto"
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  1. Article ; Online: Experiencia del Comité de Ética Asistencial del Hospital Carlos van Buren entre los años 2007-2020.

    Vega, Sebastián / Parry, Santiago / Pérez, Gabriela / Cubillos, Mariana / Araya, Liliana / Novoa, Fernando / Campos, Felipe / Vallejos, Humberto / Villegas, Víctor / Besoain, Camila / Rojas, Bernardita / Valero, Miguel / Quiroz, Vicente

    Revista medica de Chile

    2022  Volume 150, Issue 3, Page(s) 391–396

    Abstract: Background: Clinical Ethics Committees are deliberative groups whose main functions are to assess cases with ethical-clinical conflicts, to generate institutional protocols for preventive purposes, and to train health teams.: Aim: To analyze the ... ...

    Title translation Analysis of a clinical ethics committee activities at a general hospital.
    Abstract Background: Clinical Ethics Committees are deliberative groups whose main functions are to assess cases with ethical-clinical conflicts, to generate institutional protocols for preventive purposes, and to train health teams.
    Aim: To analyze the activity of a clinical ethics committee of a general hospital in the period 2007-2020.
    Material and methods: A retrospective analysis of all session records, annual reports, case resolution and documents generated by the Clinical Ethics Committee of Carlos van Buren Hospital in Valparaíso, Chile, between 2007 and 2020, was carried out.
    Results: On average, 12 cases are analyzed per year. Sixty percent correspond to requests from pediatric units and in 78% of these cases there was at least one neurological disease. In 62% of cases, the main ethical dilemma was adequacy of therapeutic effort, followed by dilemmas related to the exercise of autonomy in 18.2%. In education, two courses are identified aimed to doctors, residents, and other members of the health team. Regarding normative functions, several documents were generated at the request of the Hospital management or in different clinical situations. During COVID-19 pandemia, the active role of the committee was linked to the three main functions, namely evaluating cases, participating in morbidity and mortality meetings for preventive purposes, and issuing guidelines and recommendations for action. The active participation of Pediatric Neurology residents in the Committee, for educational and administrative purposes, stands out.
    Conclusions: The three main functions described for the ethics committees were exerted by this Committee during the evaluated period. The impact of our recommendations remain to be objectively evaluated.
    MeSH term(s) COVID-19 ; Child ; Ethics Committees ; Ethics Committees, Clinical ; Hospitals, General ; Humans ; Retrospective Studies
    Language Spanish
    Publishing date 2022-09-26
    Publishing country Chile
    Document type Journal Article
    ZDB-ID 732136-3
    ISSN 0717-6163 ; 0034-9887
    ISSN (online) 0717-6163
    ISSN 0034-9887
    DOI 10.4067/S0034-98872022000300391
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Angiomiolipoma renal complicado como causa de dolor lumbar: Caso clínico.

    Cifuentes, Melissa / Calleja, Félix / Hola, José / Daviú, Antonio / Jara, Danilo / Vallejos, Humberto

    Revista medica de Chile

    2008  Volume 136, Issue 8, Page(s) 1031–1033

    Abstract: Renal angiomyolipoma is a benign tumor formed by smooth muscle, adipose tissue and blood vessels. It is commonly found incidentally and its clinical manifestations are pain and abdominal mass or spontaneous tumor rupture with retroperitoneal bleeding. ... ...

    Title translation Renal angiomyolipoma rupture as a cause of lumbar pain: report of one case.
    Abstract Renal angiomyolipoma is a benign tumor formed by smooth muscle, adipose tissue and blood vessels. It is commonly found incidentally and its clinical manifestations are pain and abdominal mass or spontaneous tumor rupture with retroperitoneal bleeding. The clinical presentation of a hemorrhagic shock secondary to a retroperitoneal hematoma is uncommon. We report a 40 year-old male who presented to the emergency room with lumbar pain and deterioration of hemodynamic parameters. The CT scan showed a left renal injury associated to an expansive retroperitoneal process. The abdominal exploration, vascular control of the renal pedicle and nephrectomy allowed a successful outcome.
    MeSH term(s) Adult ; Angiomyolipoma/complications ; Angiomyolipoma/diagnosis ; Hematoma/etiology ; Humans ; Kidney Neoplasms/complications ; Kidney Neoplasms/diagnosis ; Low Back Pain/etiology ; Male ; Retroperitoneal Space ; Rupture, Spontaneous ; Tomography, X-Ray Computed
    Language Spanish
    Publishing date 2008-08
    Publishing country Chile
    Document type Case Reports ; English Abstract ; Journal Article
    ZDB-ID 732136-3
    ISSN 0717-6163 ; 0034-9887
    ISSN (online) 0717-6163
    ISSN 0034-9887
    DOI /S0034-98872008000800011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Fulminant hepatic failure associated with propylthiouracil.

    Ruiz, Jorge K / Rossi, Giorgio V / Vallejos, Humberto A / Brenet, Rosemarie W / Lopez, Isabel B / Escribano, Alfonso A

    The Annals of pharmacotherapy

    2003  Volume 37, Issue 2, Page(s) 224–228

    Abstract: Objective: To report 2 fatal cases of fulminant hepatic failure associated with propylthiouracil treatment against hyperthyroidism.: Case summary: Two women, 30 and 32 years old with no previous liver disease, were treated with propylthiouracil ... ...

    Abstract Objective: To report 2 fatal cases of fulminant hepatic failure associated with propylthiouracil treatment against hyperthyroidism.
    Case summary: Two women, 30 and 32 years old with no previous liver disease, were treated with propylthiouracil against Graves' disease. Both patients developed jaundice after a 4- and 5-month treatment period, respectively. The disease was similar to viral hepatitis, with a progressive course to severe liver dysfunction and death, along with multisystem organ failure despite extensive therapeutic measures. One of the patients was pregnant and subsequently miscarried. Neither patient had a history of alcoholism, drug abuse, blood transfusion, or exposure to hepatitis A, B, or C. Extrahepatic obstruction was ruled out with an abdominal ultrasonogram. Serologic studies and immunologic tests were negative. A submassive necrosis was shown in a postmortem histologic study.
    Discussion: Naranjo probability scale criteria applied to both cases confirm the adverse reactions as probable. These cases fit the requirements of drug hepatotoxicity proposed by Hanson and the Council of the International Organization of Medical Sciences. Eight deaths associated to propylthiouracil were found in our review of the medical literature up to December 2000.
    Conclusions: Despite the widespread use of propylthiouracil, fulminant hepatitis with death is exceptionally rare; these 2 cases could be added to the fatal outcomes published to date.
    MeSH term(s) Adult ; Chemical and Drug Induced Liver Injury/pathology ; Fatal Outcome ; Female ; Humans ; Hyperthyroidism/drug therapy ; Propylthiouracil/adverse effects
    Chemical Substances Propylthiouracil (721M9407IY)
    Language English
    Publishing date 2003-02
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 1101370-9
    ISSN 1542-6270 ; 1060-0280
    ISSN (online) 1542-6270
    ISSN 1060-0280
    DOI 10.1177/106002800303700213
    Database MEDical Literature Analysis and Retrieval System OnLINE

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