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Article ; Online: Prevalence of transmitted drug resistance and phylogenetic analysis of HIV-1 among antiretroviral therapy-naïve patients in Northern Vietnam from 2019 to 2022.

Tran, Giang Van / Hayashida, Tsunefusa / Dang, An Luong-Dieu / Nagai, Moeko / Matsumoto, Shoko / Tran, Linh Khanh / Le, Hoa Nguyen-Minh / Van, Trang Dinh / Tanuma, Junko / Pham, Thach Ngoc / Oka, Shinichi

Global health & medicine

2024 Volume 6, Issue 2, Page(s) 117–123

Abstract: Since the rapid expansion of antiretroviral therapy (ART) for HIV, transmitted drug resistance (TDR) has become a major concern in Vietnam. HIV services there are transitioning to be covered by social insurance. Access to pre-exposure prophylaxis (PrEP) ... ...

Abstract	Since the rapid expansion of antiretroviral therapy (ART) for HIV, transmitted drug resistance (TDR) has become a major concern in Vietnam. HIV services there are transitioning to be covered by social insurance. Access to pre-exposure prophylaxis (PrEP) is being expanded to tackle the growing HIV epidemic among men who have sex with men. Therefore, a cross-sectional study was conducted at 10 ART facilities in Northern Vietnam from 9
Language	English
Publishing date	2024-01-04
Publishing country	Japan
Document type	Journal Article
ZDB-ID	3140544-7
ISSN	2434-9194 ; 2434-9194 ; 2434-9186
ISSN (online)	2434-9194
ISSN	2434-9194 ; 2434-9186
DOI	10.35772/ghm.2023.01112
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Identification of New Circulating Recombinant Form of HIV-1 CRF127_07109 in Northern Vietnam.

Hayashida, Tsunefusa / Tran, Linh Khanh / Dang, An Luong-Dieu / Nagai, Moeko / Matsumoto, Shoko / Le, Hoa Nguyen-Minh / Van, Trang Dinh / Tran, Giang Van / Tanuma, Junko / Pham, Thach Ngoc / Oka, Shinichi

AIDS research and human retroviruses

2024

Abstract: Some candidates of a new circulating recombinant form (CRF) of HIV-1 were found in northern Vietnam in our previous study. We succeeded in near full-length sequencing using MinION with plasma samples from 12 people living with HIV. Three of the samples ... ...

Abstract	Some candidates of a new circulating recombinant form (CRF) of HIV-1 were found in northern Vietnam in our previous study. We succeeded in near full-length sequencing using MinION with plasma samples from 12 people living with HIV. Three of the samples were CRF109_0107, which was recently reported in China. Three others were the newly identified CRF127_07109, while six of them were considered to be CRF127_07109-related unique recombinant forms (URFs). The time to the most recent common ancestor of CRF127_07109 was estimated to be between 2015 and 2019. Our findings showed that CRF127_07109 and related URFs were generated recently in northern Vietnam, rather than migrated independently to northern Vietnam.
Language	English
Publishing date	2024-05-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	639130-8
ISSN	1931-8405 ; 0889-2229
ISSN (online)	1931-8405
ISSN	0889-2229
DOI	10.1089/AID.2024.0022
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Article ; Online: Complete Genome Sequences, Derived by Next-Generation Sequencing, of JC Polyomavirus Strains Isolated from Vietnamese Renal Transplant Recipients.

Van, Trang Dinh / Rockett, Rebecca J / Ha, An Phan Hai / Nguyen, Trung Vu / Dwyer, Dominic E

Microbiology resource announcements

2020 Volume 9, Issue 2

Abstract: JC polyomavirus (JCPyV) may cause clinical syndromes such as progressive multifocal leukoencephalopathy in immunocompromised patients. Here, we report seven complete genome sequences of JCPyV genotype 7A, generated directly from urine samples from ... ...

Abstract	JC polyomavirus (JCPyV) may cause clinical syndromes such as progressive multifocal leukoencephalopathy in immunocompromised patients. Here, we report seven complete genome sequences of JCPyV genotype 7A, generated directly from urine samples from Vietnamese renal transplant recipients by using rolling-circle amplification and next-generation sequencing.
Language	English
Publishing date	2020-01-09
Publishing country	United States
Document type	Journal Article
ISSN	2576-098X
ISSN (online)	2576-098X
DOI	10.1128/MRA.01350-19
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Article ; Online: Deep Sequencing of Urine Specimens Detects Two BK Polyomavirus Genotypes in a Hematopoietic Stem Cell Transplant Recipient.

Van, Trang Dinh / Dwyer, Dominic E / Jeoffreys, Neisha / Kok, Jen / Nankivell, Brian J / Rockett, Rebecca J

Microbiology resource announcements

2020 Volume 9, Issue 5

Abstract: BK polyomavirus (BKPyV) is an important pathogen in transplant recipients. We report four draft BKPyV genomes, three of BKPyV genotype I (subtype I-b2) (AUS-105, AUS-106, and AUS-108) and one of genotype II (AUS-107). These draft genomes were identified ... ...

Abstract	BK polyomavirus (BKPyV) is an important pathogen in transplant recipients. We report four draft BKPyV genomes, three of BKPyV genotype I (subtype I-b2) (AUS-105, AUS-106, and AUS-108) and one of genotype II (AUS-107). These draft genomes were identified in longitudinal urine samples collected from a single hematopoietic stem cell transplant recipient.
Language	English
Publishing date	2020-01-30
Publishing country	United States
Document type	Journal Article
ISSN	2576-098X
ISSN (online)	2576-098X
DOI	10.1128/MRA.01461-19
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Article ; Online: Genetic diversity of SARS-CoV-2 and clinical, epidemiological characteristics of COVID-19 patients in Hanoi, Vietnam.

Nguyen, Tam Thi / Pham, Thach Ngoc / Van, Trang Dinh / Nguyen, Trang Thu / Nguyen, Diep Thi Ngoc / Le, Hoa Nguyen Minh / Eden, John-Sebastian / Rockett, Rebecca J / Nguyen, Thuong Thi Hong / Vu, Bich Thi Ngoc / Tran, Giang Van / Le, Tan Van / Dwyer, Dominic E / van Doorn, H Rogier

PloS one

2020 Volume 15, Issue 11, Page(s) e0242537

Abstract: A second cluster of COVID-19 cases imported from Europe occured in Vietnam from early March 2020. We describe 44 SARS-CoV-2 RT-PCR positive patients (cycle threshold value <30) admitted to the National Hospital for Tropical Diseases in Hanoi between ... ...

Abstract	A second cluster of COVID-19 cases imported from Europe occured in Vietnam from early March 2020. We describe 44 SARS-CoV-2 RT-PCR positive patients (cycle threshold value <30) admitted to the National Hospital for Tropical Diseases in Hanoi between March 6 and April 15 2020. Whole SARS-CoV-2 genomes from these patients were sequenced using Illumina Miseq and analysed for common genetic variants and relationships to local and globally circulating strains. Results showed that 32 cases were Vietnamese with a median age of 37 years (range 15-74 years), and 23 were male. Most cases were acquired outside Vietnam, mainly from the UK (n = 15), other European countries (n = 14), Russia (n = 6) and countries in Asia (n = 3). No cases had travelled from China. Forty-one cases had symptoms at admission, typically dry cough (n = 36), fever (n = 20), sore throat (n = 14) and diarrhoea (n = 12). Hospitalisation was long with a median of 25 days, most commonly from 20-29 days. All SARS-CoV-2 genomes were similar (92-100% sequence homology) to the reference sequence Wuhan_1 (NC_045512), and 32 strains belonged to the B.1.1 lineage. The three most common variants were linked, and included C3037T, C14408T (nsp12: P323L) and A23403G (S: D614G) mutations. This group of mutations often accompanied variant C241T (39/44 genomes) or GGG 28881..28883 AAC (33/44 genomes). The prevalence of the former reflected probable European origin of viruses, and the transition D614G was dominant in Vietnam. New variants were identified; however, none could be associated with disease severity.
MeSH term(s)	Adolescent ; Adult ; Aged ; Betacoronavirus/genetics ; Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/virology ; Female ; Genetic Variation ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; Prevalence ; SARS-CoV-2 ; Travel-Related Illness ; Vietnam ; Young Adult
Keywords	covid19
Language	English
Publishing date	2020-11-17
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0242537
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Genetic diversity of SARS-CoV-2 and clinical, epidemiological characteristics of COVID-19 patients in Hanoi, Vietnam

PLoS One

Abstract	A second cluster of COVID-19 cases imported from Europe occured in Vietnam from early March 2020. We describe 44 SARS-CoV-2 RT-PCR positive patients (cycle threshold value <30) admitted to the National Hospital for Tropical Diseases in Hanoi between March 6 and April 15 2020. Whole SARS-CoV-2 genomes from these patients were sequenced using Illumina Miseq and analysed for common genetic variants and relationships to local and globally circulating strains. Results showed that 32 cases were Vietnamese with a median age of 37 years (range 15-74 years), and 23 were male. Most cases were acquired outside Vietnam, mainly from the UK (n = 15), other European countries (n = 14), Russia (n = 6) and countries in Asia (n = 3). No cases had travelled from China. Forty-one cases had symptoms at admission, typically dry cough (n = 36), fever (n = 20), sore throat (n = 14) and diarrhoea (n = 12). Hospitalisation was long with a median of 25 days, most commonly from 20-29 days. All SARS-CoV-2 genomes were similar (92-100% sequence homology) to the reference sequence Wuhan_1 (NC_045512), and 32 strains belonged to the B.1.1 lineage. The three most common variants were linked, and included C3037T, C14408T (nsp12: P323L) and A23403G (S: D614G) mutations. This group of mutations often accompanied variant C241T (39/44 genomes) or GGG 28881..28883 AAC (33/44 genomes). The prevalence of the former reflected probable European origin of viruses, and the transition D614G was dominant in Vietnam. New variants were identified; however, none could be associated with disease severity.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #930647
Database	COVID19

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Article ; Online: Sero-Prevalence of SARS-CoV-2 Antibodies in High-Risk Populations in Vietnam.

Hasan, Tasnim / Pham, Thach Ngoc / Nguyen, Thu Anh / Le, Hien Thi Thu / Van Le, Duyet / Dang, Thuy Thi / Van, Trang Dinh / Pham, Yen Ngoc / Nguyen, Ha Viet / Tran, Giang Linh / Nguyen, Van Thi Cam / Nguyen, Thanh Trung / Truong, Viet Quang / Dao, Than Huu / Le, Chung Thanh / Truong, Nam Tan / Vo, Hoang Trung / Le, Phuc Thanh / Nguyen, Thao Thanh /

Van Luu, Vinh / Nguyen, Vinh Dai / Toelle, Brett G / Marks, Guy B / Fox, Greg J

International journal of environmental research and public health

2021 Volume 18, Issue 12

Abstract: As a response to the coronavirus disease 2019 (COVID-19) pandemic, Vietnam enforced strict quarantine, contact tracing and physical distancing policies resulting in one of the lowest numbers of individuals infected with severe acute respiratory syndrome- ... ...

Abstract	As a response to the coronavirus disease 2019 (COVID-19) pandemic, Vietnam enforced strict quarantine, contact tracing and physical distancing policies resulting in one of the lowest numbers of individuals infected with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) globally. This study aimed to determine the prevalence of SARS-CoV-2 antibody positivity among high-risk populations in Vietnam. A prevalence survey was undertaken within four communities in Vietnam, where at least two COVID-19 cases had been confirmed. Participants were classified according to the location of exposure: household contacts, close contacts, community members, and healthcare workers (HCWs) responsible for treating COVID-19 cases. Participants completed a baseline questionnaire and SARS-CoV-2 IgG antibodies were quantified using a commercial assay. A total of 3049 community members and 149 health care workers consented to the study. Among 13 individuals who were seropositive (0.4%), five household contacts (5/27, 18.5%), one close contact (1/53, 1.9%), and seven community members (7/2954, 0.2%) had detectable SARS-CoV-2 antibodies. All HCWs were negative for SARS-CoV-2 antibodies. Participants were tested a median of 15.1 (interquartile range from 14.9 to 15.2) weeks after exposure. Our study found a low prevalence of SARS-CoV-2 antibodies in high-risk communities and healthcare workers in communities in Vietnam with known COVID-19 cases.
MeSH term(s)	Antibodies, Viral ; COVID-19 ; Health Personnel ; Humans ; Pandemics ; Prevalence ; SARS-CoV-2 ; Seroepidemiologic Studies ; Vietnam/epidemiology
Chemical Substances	Antibodies, Viral
Language	English
Publishing date	2021-06-11
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1660-4601
ISSN (online)	1660-4601
DOI	10.3390/ijerph18126353
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Article: Antibiotic susceptibility and molecular epidemiology of

Van, Trang Dinh / Dinh, Quynh-Dao / Vu, Phu Dinh / Nguyen, Trung Vu / Pham, Ca Van / Dao, Trinh Tuyet / Phung, Cam Dac / Hoang, Ha Thu Thi / Tang, Nga Thi / Do, Nga Thuy / Nguyen, Kinh Van / Wertheim, Heiman

Journal of global antimicrobial resistance

2014 Volume 2, Issue 4, Page(s) 318–321

Abstract: Acinetobacter calcoaceticus- ... ...

Abstract	Acinetobacter calcoaceticus-baumannii
Language	English
Publishing date	2014-12
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2710046-7
ISSN	2213-7173 ; 2213-7165
ISSN (online)	2213-7173
ISSN	2213-7165
DOI	10.1016/j.jgar.2014.05.003
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Article ; Online: Spatiotemporal Evolution of SARS-CoV-2 Alpha and Delta Variants during a Large Nationwide Outbreak in Vietnam, 2021

Nguyen, Tam Thi / Nguyen, Anh To / Trinh, Tung Son / Pham, Thach Ngoc / Nguyen, Dung Thanh / Van, Trang Dinh / Le, Hung Manh / Trinh, Dien Cong / Nghiem, Ngoc My / Le, Duyet Van / Phan, Cuong Manh / Hoang, Phuong Vu Mai / Pham, Thai Quang / Nguyen, Tung Le Nhu / Dinh, Man Nguyen Huy / Nguyen, Phong Thanh / Vo, Quang Minh / Pham, Thoa Thi Ngoc / Nguyen, Truong Thanh /

Tran, Thao Nguyen Phuong / Dao, Linh Phuong / Ngo, Tai Tan / Ho, Bao The / Vo, Vuong Trong / Huynh, Nhung Thi Kim / Phan, Hong Nu Dieu / Le, Hanh Thi Phuoc / Le, Chung Thanh / Nguyen, Nhan Thi Thanh / Ton, Thanh That / Do, Hung Thai / Huynh, Mai Kim / Trinh, Long Hoang / Nguyen, Trang Thu / Nguyen, Thuong Thi Hong / Nguyen, Hong Thi Thu / Le, Nhu Nguyen Truc / Nguyen, Ny Thi Han / Cao, Thuy Thu / Le, Thanh Kim / Lam, Nguyet Anh / Le, Mai Thi Quynh / Tang, Thuong Chi / Le, Nga Hong / Tran, Thanh Tan / Thwaites, Guy / van Doorn, H.Rogier / Nguyen, Chau Van Vinh / Kesteman, Thomas / Le, Tan Van

medRxiv

Abstract: In 2021, Vietnam experienced a large nationwide outbreak of COVID-19, with over 1.7 million infections and 32,000 deaths. We generated 1,303 SARS-CoV-2 whole-genome sequences, and mapped out the public health measures alongside the evolutionary ... ...

Abstract	In 2021, Vietnam experienced a large nationwide outbreak of COVID-19, with over 1.7 million infections and 32,000 deaths. We generated 1,303 SARS-CoV-2 whole-genome sequences, and mapped out the public health measures alongside the evolutionary trajectory of the pathogen. The Alpha variant caused sporadic outbreaks in early 2021 prior to the upsurge in cases associated with the Delta variant from June onward. The Delta variant outbreak was almost entirely confined to the AY.57 lineage, accounting for 99.2% of 1,212 Delta variant sequences, and resulting from a single introduction. Viral dispersal from the north, where it was first introduced into Vietnam, to the south, marked the start of the nationwide outbreak, with the south subsequently seeding the virus back to the other regions. Distinct AY.57 phylogenetic clusters in different regions of Vietnam were documented, pointing to the impact of in-country lockdown. Genomic surveillance is critical to inform pandemic response.
Keywords	covid19
Language	English
Publishing date	2023-01-05
Publisher	Cold Spring Harbor Laboratory Press
Document type	Article ; Online
DOI	10.1101/2023.01.03.22283384
Database	COVID19

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