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  1. Book ; Online ; E-Book: Locoregional tumor therapy

    Van Cutsem, Eric / Vogl, Thomas J. / Orsi, Franco / Sobrero, Alberto

    2018  

    Author's details Eric Van Cutsem, Thomas J. Vogl, Franco Orsi, Alberto Sobrero editors
    Keywords Medicine ; Interventional radiology ; Oncology ; Surgical oncology
    Subject code 616.994
    Language English
    Size 1 Online-Ressource (viii, 274 Seiten), Illustrationen
    Edition Second edition
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019740344
    ISBN 978-3-319-69947-9 ; 9783319699462 ; 3-319-69947-4 ; 3319699466
    DOI 10.1007/978-3-319-69947-9
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: KRAS G12C inhibition with sotorasib in metastatic colorectal cancer.

    Severi, Christophe / Van Cutsem, Eric

    Annals of palliative medicine

    2022  Volume 11, Issue 8, Page(s) 2792–2795

    MeSH term(s) Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/genetics ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/genetics ; Piperazines ; Proto-Oncogene Proteins p21(ras)/genetics ; Pyridines ; Pyrimidines
    Chemical Substances KRAS protein, human ; Piperazines ; Pyridines ; Pyrimidines ; sotorasib (2B2VM6UC8G) ; Proto-Oncogene Proteins p21(ras) (EC 3.6.5.2)
    Language English
    Publishing date 2022-08-19
    Publishing country China
    Document type Journal Article
    ZDB-ID 2828544-X
    ISSN 2224-5839 ; 2224-5839
    ISSN (online) 2224-5839
    ISSN 2224-5839
    DOI 10.21037/apm-22-532
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The Role of cMET in Gastric Cancer-A Review of the Literature.

    Van Herpe, Filip / Van Cutsem, Eric

    Cancers

    2023  Volume 15, Issue 7

    Abstract: Gastric cancer (GC) is an important cause of cancer worldwide with over one million new cases yearly. The vast majority of cases present in stage IV disease, and it still bears a poor prognosis. However, since 2010, progress has been made with the ... ...

    Abstract Gastric cancer (GC) is an important cause of cancer worldwide with over one million new cases yearly. The vast majority of cases present in stage IV disease, and it still bears a poor prognosis. However, since 2010, progress has been made with the introduction of targeted therapies against HER2 and with checkpoint inhibitors (PDL1). More agents interfering with other targets (FGFR2B, CLDN18.2) are being investigated. cMET is a less frequent molecular target that has been studied for gastric cancer. It is a proto-oncogene that leads to activation of the MAPK pathway and the PI3K pathway, which is responsible for activating the MTOR pathway. The prevalence of cMET is strongly debated as different techniques are being used to detect MET-driven tumors. Because of the difference in diagnostic assays, selecting patients who benefit from cMET inhibitors is difficult. In this review, we discuss the pathway of cMET, its clinical significance and the different diagnostic assays that are currently used, such as immunohistochemy (IHC), fluorescence in situ hybridization (FISH), the H-score and next-generation sequencing (NGS). Next, we discuss all the current data on cMET inhibitors in gastric cancer. Since the data on cMET inhibitors are very heterogenous, it is difficult to provide a general consensus on the outcome, as inclusion criteria differ between trials. Diagnosing cMET-driven gastric tumors is difficult, and potentially the only accurate determination of cMET overexpression/amplification may be next-generation sequencing (NGS).
    Language English
    Publishing date 2023-03-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15071976
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: The multidisciplinary management of gastrointestinal cancer

    Van Cutsem, Eric

    (Best practice & research : Clinical gastroenterology ; 21,6)

    2007  

    Author's details E. Van Cutsem, guest ed
    Series title Best practice & research : Clinical gastroenterology ; 21,6
    Best practice & research
    Best practice & research ; Clinical gastroenterology
    Collection Best practice & research
    Best practice & research ; Clinical gastroenterology
    Language English
    Size S. 919 - 1108 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT015401301
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: Immunotherapy Rechallenge After Checkpoint Inhibitor Induced Hemophagocytic Lymphohistiocytosis: A Case Report and Literature Review.

    Geusens, Dorien / Dierickx, Daan / Carton, Saskia / Van Cutsem, Eric / Dekervel, Jeroen

    Clinical colorectal cancer

    2024  

    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2112638-0
    ISSN 1938-0674 ; 1533-0028
    ISSN (online) 1938-0674
    ISSN 1533-0028
    DOI 10.1016/j.clcc.2024.01.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Conference proceedings: Highlights in gastrointestinal oncology

    Van Cutsem, Eric

    proceedings of the Falk Symposium 149 held in Berlin, Germany, October 1 - 2, 2005

    (Falk symposium series ; 149)

    2006  

    Event/congress Falk Symposium (149, 2005, Berlin)
    Author's details ed. by E. van Cutsem
    Series title Falk symposium series ; 149
    Collection
    Language English
    Size XIII, 184 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT014768467
    ISBN 978-1-4020-5108-1 ; 1-4020-5108-5
    Database Catalogue ZB MED Medicine, Health

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  7. Book ; Conference proceedings: ESMO 13th World Congress on Gastrointestinal Cancer

    Dicato, Mario / Van Cutsem, Eric

    22 - 25 June 2011, Barcelona, Spain

    (Annals of oncology ; 22, Suppl. 5)

    2011  

    Institution European Society for Medical Oncology
    Event/congress World Congress on Gastrointestinal Cancer (13, 2011, Barcelona)
    Author's details chairs: Mario Dicato ; Eric van Cutsem
    Series title Annals of oncology ; 22, Suppl. 5
    Collection
    Language English
    Size 144 S. : graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    HBZ-ID HT016888919
    Database Catalogue ZB MED Medicine, Health

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  8. Book ; Conference proceedings: Second Clinical Investigators Update Meeting on Gastrointestinal Cancer

    Van Cutsem, Eric

    11th October 2003, Tenerife, Spain

    (EJC Supplements ; 2,7)

    2004  

    Event/congress Clinical Investigators Update Meeting on Gastrointestinal Cancer (2, 2003)
    Author's details guest ed. Eric Van Cutsem
    Series title EJC Supplements ; 2,7
    European journal of cancer
    Collection European journal of cancer
    Language English
    Size 62 S. : graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT014087195
    Database Catalogue ZB MED Medicine, Health

    Kategorien

  9. Book ; Conference proceedings: ESMO conference: 12th World Congress on Gastrointestinal Cancer

    Dicato, Mario / Van Cutsem, Eric

    30 June to 3 July, 2010: Barcelona, Spain

    (Annals of oncology ; 21, Suppl. 6)

    2010  

    Institution European Society for Medical Oncology
    Event/congress World Congress on Gastrointestinal Cancer (12, 2010, Barcelona)
    Author's details chairs: Mario Dicato ; Eric van Cutsem
    Series title Annals of oncology ; 21, Suppl. 6
    Collection
    Language English
    Size vi132 S.
    Publisher Oxford Univ. Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    HBZ-ID HT016475454
    Database Catalogue ZB MED Medicine, Health

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  10. Book: Oral tegafur uracil plus leucovorin in metastatic colorectal cancer: clinical insights

    Van Cutsem, Eric

    based on a round table expert meeting, October 2002, Nice

    (Anti-cancer drugs ; 14, Suppl. 2)

    2003  

    Title variant Oral tegafur-uracil plus leucovorin in metastaticcolorectal cancer: clinical insights
    Author's details guest ed.: Eric van Cutsem
    Series title Anti-cancer drugs ; 14, Suppl. 2
    Collection
    Language English
    Size S10 S.
    Publisher Lippincott Williams & Wilkins
    Publishing place London
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT013813038
    Database Catalogue ZB MED Medicine, Health

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