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  1. Article ; Online: Candida auris in an Australian health care facility: importance of screening high risk patients.

    Worth, Leon J / Harrison, Simon J / Dickinson, Michael / van Diemen, Annaliese / Breen, Jennifer / Harper, Susan / Marshall, Caroline / Williamson, Deborah A / Thursky, Karin A / Slavin, Monica A

    The Medical journal of Australia

    2020  Volume 212, Issue 11, Page(s) 510–511.e1

    MeSH term(s) Adult ; Aged ; Australia ; Candida ; Candidiasis/diagnosis ; Candidiasis/microbiology ; Candidiasis/transmission ; Cross Infection/diagnosis ; Cross Infection/microbiology ; Cross Infection/prevention & control ; Disease Transmission, Infectious/prevention & control ; Health Facilities/standards ; Humans ; Male ; Mass Screening/methods ; Mass Screening/standards
    Language English
    Publishing date 2020-05-24
    Publishing country Australia
    Document type Case Reports ; Journal Article
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    DOI 10.5694/mja2.50612
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.398: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Victorian Specialist Immunisation Services (VicSIS) - bolstering adult clinics for COVID-19 vaccines.

    Gordon, Sally F / Virah Sawmy, Elise / Duckworth, Eleanor / Wolthuizen, Michelle / Clothier, Hazel J / Chea, Malinda / Tenneti, Naveen / Blow, Ngaree / Buttery, Jim P / de Luca, Joseph / Korman, Tony M / Barnes, Sara / Slade, Charlotte / Maggs, Callum / Giles, Michelle L / Teh, Benjamin W / Aboltins, Craig / Langan, Katherine M / Van Diemen, Annaliese /
    Crawford, Nigel W

    Human vaccines & immunotherapeutics

    2022  Volume 18, Issue 5, Page(s) 2052701

    Abstract: The Victorian Specialist Immunization Services (VicSIS) was established in Victoria, Australia, in February 2021, aiming to enhance vaccine safety services for Coronavirus disease (COVID-19) vaccines. VicSIS supports practitioners and patients with ... ...

    Abstract The Victorian Specialist Immunization Services (VicSIS) was established in Victoria, Australia, in February 2021, aiming to enhance vaccine safety services for Coronavirus disease (COVID-19) vaccines. VicSIS supports practitioners and patients with complex vaccine safety questions, including those who experience adverse events following immunization (AEFI) after COVID-19 vaccines. VicSIS provides individual vaccination recommendations, allergy testing, vaccine challenges, and vaccination under supervision. VicSIS initially comprised of eight adult COVID-19 specialist vaccination clinics, subsequently, expanding to better support pediatric patients as the Australian vaccine roll-out extended to adolescents and children. Since their establishment to September 2021, the inaugural VicSIS clinics received a total of 26,401 referrals and reviewed 6,079 patients. Consults were initially predominantly for pre-vaccination reviews, later predominantly becoming post-vaccination AEFI reviews as the program progressed. Regardless of the type of consult, the most common consult outcome was a recommendation for routine vaccination (73% and 55% of consult outcomes respectively). VicSIS is an integral component of the COVID-19 vaccination program and supports confidence in COVID-19 vaccine safety by providing consistent advice across the state. VicSIS aims to strengthen the health system through the pandemic, bolstering specialist immunization services beyond COVID-19 vaccines, including training the next generation of vaccinology experts.
    MeSH term(s) Adolescent ; Adult ; Adverse Drug Reaction Reporting Systems ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Child ; Humans ; Immunization/adverse effects ; Population Surveillance ; Vaccination/adverse effects ; Vaccines/adverse effects ; Victoria
    Chemical Substances COVID-19 Vaccines ; Vaccines
    Language English
    Publishing date 2022-04-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2664176-8
    ISSN 2164-554X ; 2164-5515
    ISSN (online) 2164-554X
    ISSN 2164-5515
    DOI 10.1080/21645515.2022.2052701
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6967: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Genomics for Molecular Epidemiology and Detecting Transmission of Carbapenemase-Producing

    Sherry, Norelle L / Lane, Courtney R / Kwong, Jason C / Schultz, Mark / Sait, Michelle / Stevens, Kerrie / Ballard, Susan / Gonçalves da Silva, Anders / Seemann, Torsten / Gorrie, Claire L / Stinear, Timothy P / Williamson, Deborah A / Brett, Judith / van Diemen, Annaliese / Easton, Marion / Howden, Benjamin P

    Journal of clinical microbiology

    2019  Volume 57, Issue 9

    Abstract: Carbapenemase- ... ...

    Abstract Carbapenemase-producing
    MeSH term(s) Aged ; Bacterial Proteins/genetics ; Bacteriological Techniques ; Carbapenem-Resistant Enterobacteriaceae/classification ; Carbapenem-Resistant Enterobacteriaceae/genetics ; Carbapenem-Resistant Enterobacteriaceae/isolation & purification ; Disease Transmission, Infectious ; Enterobacteriaceae Infections/microbiology ; Enterobacteriaceae Infections/transmission ; Female ; Humans ; Male ; Middle Aged ; Molecular Diagnostic Techniques/methods ; Molecular Epidemiology/methods ; Molecular Typing/methods ; Multiplex Polymerase Chain Reaction ; Victoria ; Whole Genome Sequencing ; beta-Lactamases/genetics
    Chemical Substances Bacterial Proteins ; beta-Lactamases (EC 3.5.2.6) ; carbapenemase (EC 3.5.2.6)
    Language English
    Publishing date 2019-08-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 390499-4
    ISSN 1098-660X ; 0095-1137
    ISSN (online) 1098-660X
    ISSN 0095-1137
    DOI 10.1128/JCM.00573-19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1188: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Tracking the COVID-19 pandemic in Australia using genomics.

    Seemann, Torsten / Lane, Courtney R / Sherry, Norelle L / Duchene, Sebastian / Gonçalves da Silva, Anders / Caly, Leon / Sait, Michelle / Ballard, Susan A / Horan, Kristy / Schultz, Mark B / Hoang, Tuyet / Easton, Marion / Dougall, Sally / Stinear, Timothy P / Druce, Julian / Catton, Mike / Sutton, Brett / van Diemen, Annaliese / Alpren, Charles /
    Williamson, Deborah A / Howden, Benjamin P

    Nature communications

    2020  Volume 11, Issue 1, Page(s) 4376

    Abstract: Genomic sequencing has significant potential to inform public health management for SARS-CoV-2. Here we report high-throughput genomics for SARS-CoV-2, sequencing 80% of cases in Victoria, Australia (population 6.24 million) between 6 January and 14 ... ...

    Abstract Genomic sequencing has significant potential to inform public health management for SARS-CoV-2. Here we report high-throughput genomics for SARS-CoV-2, sequencing 80% of cases in Victoria, Australia (population 6.24 million) between 6 January and 14 April 2020 (total 1,333 COVID-19 cases). We integrate epidemiological, genomic and phylodynamic data to identify clusters and impact of interventions. The global diversity of SARS-CoV-2 is represented, consistent with multiple importations. Seventy-six distinct genomic clusters were identified, including large clusters associated with social venues, healthcare and cruise ships. Sequencing sequential samples from 98 patients reveals minimal intra-patient SARS-CoV-2 genomic diversity. Phylodynamic modelling indicates a significant reduction in the effective viral reproductive number (R
    MeSH term(s) Adult ; Australia/epidemiology ; Betacoronavirus/genetics ; Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Female ; Genome, Viral ; Genomics/methods ; Health Personnel ; Humans ; Male ; Middle Aged ; Molecular Epidemiology ; Pandemics ; Phylogeny ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; Public Health ; Retrospective Studies ; SARS-CoV-2 ; Travel
    Keywords covid19
    Language English
    Publishing date 2020-09-01
    Publishing country England
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-020-18314-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Search and Contain: Impact of an Integrated Genomic and Epidemiological Surveillance and Response Program for Control of Carbapenemase-producing Enterobacterales.

    Lane, Courtney R / Brett, Judith / Schultz, Mark / Gorrie, Claire L / Stevens, Kerrie / Cameron, Donna R M / St George, Siobhan / van Diemen, Annaliese / Easton, Marion / Stuart, Rhonda L / Sait, Michelle / Peleg, Anton Y / Stewardson, Andrew J / Cheng, Allen C / Spelman, Denis W / Waters, Mary Jo / Ballard, Susan A / Sherry, Norelle L / Williamson, Deborah A /
    Romanes, Finn / Sutton, Brett / Kwong, Jason C / Seemann, Torsten / Goncalves da Silva, Anders / Stephens, Nicola / Howden, Benjamin P

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2020  Volume 73, Issue 11, Page(s) e3912–e3920

    Abstract: Background: Multiresistant organisms (MROs) pose a critical threat to public health. Population-based programs for control of MROs such as carbapenemase-producing Enterobacterales (CPE) have emerged and evaluation is needed. We assessed the feasibility ... ...

    Abstract Background: Multiresistant organisms (MROs) pose a critical threat to public health. Population-based programs for control of MROs such as carbapenemase-producing Enterobacterales (CPE) have emerged and evaluation is needed. We assessed the feasibility and impact of a statewide CPE surveillance and response program deployed across Victoria, Australia (population 6.5 million).
    Methods: A prospective multimodal intervention including active screening, carrier isolation, centralized case investigation, and comparative pathogen genomics was implemented. We analyzed trends in CPE incidence and clinical presentation, risk factors, and local transmission over the program's first 3 years (2016-2018).
    Results: CPE case ascertainment increased over the study period to 1.42 cases/100 000 population, linked to increased screening without a concomitant rise in active clinical infections (0.45-0.60 infections/100 000 population, P = .640). KPC-2 infection decreased from 0.29 infections/100 000 population prior to intervention to 0.03 infections/100 000 population in 2018 (P = .003). Comprehensive case investigation identified instances of overseas community acquisition. Median time between isolate referral and genomic and epidemiological assessment for local transmission was 11 days (IQR, 9-14). Prospective surveillance identified numerous small transmission networks (median, 2; range, 1-19 cases), predominantly IMP and KPC, with median pairwise distance of 8 (IQR, 4-13) single nucleotide polymorphisms; low diversity between clusters of the same sequence type suggested genomic cluster definitions alone are insufficient for targeted response.
    Conclusions: We demonstrate the value of centralized CPE control programs to increase case ascertainment, resolve risk factors, and identify local transmission through prospective genomic and epidemiological surveillance; methodologies are transferable to low-prevalence settings and MROs globally.
    MeSH term(s) Bacterial Proteins/genetics ; Enterobacteriaceae Infections/epidemiology ; Enterobacteriaceae Infections/prevention & control ; Genomics ; Humans ; Prospective Studies ; Victoria ; beta-Lactamases/genetics
    Chemical Substances Bacterial Proteins ; beta-Lactamases (EC 3.5.2.6) ; carbapenemase (EC 3.5.2.6)
    Language English
    Publishing date 2020-07-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa972
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1505: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 480: Show issues

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  6. Article ; Online: Tracking the COVID-19 pandemic in Australia using genomics

    Seemann, Torsten / Lane, Courtney R. / Sherry, Norelle L. / Duchene, Sebastian / Gonçalves da Silva, Anders / Caly, Leon / Sait, Michelle / Ballard, Susan A. / Horan, Kristy / Schultz, Mark B. / Hoang, Tuyet / Easton, Marion / Dougall, Sally / Stinear, Timothy P. / Druce, Julian / Catton, Mike / Sutton, Brett / van Diemen, Annaliese / Alpren, Charles /
    Williamson, Deborah A. / Howden, Benjamin P.

    Nature Communications

    2020  Volume 11, Issue 1

    Keywords General Biochemistry, Genetics and Molecular Biology ; General Physics and Astronomy ; General Chemistry ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2553671-0
    ISSN 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-020-18314-x
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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