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  1. Article ; Online: Nasal polyp syndrome: a patient-centred term for CRSwNP by EUFOREA.

    Teeling, T / Djouder, C / Laurens, H / Preyra, J H / Shire, C M E / Van Staeyen, E / Conti, D M / Scadding, G K / Hellings, P W

    Frontiers in allergy

    2024  Volume 5, Page(s) 1372919

    Abstract: Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is a chronic inflammatory disease of the nose and paranasal sinus cavities that significantly affects well-being and social function, particularly in young adults and middle-aged populations. CRSwNP is a ... ...

    Abstract Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is a chronic inflammatory disease of the nose and paranasal sinus cavities that significantly affects well-being and social function, particularly in young adults and middle-aged populations. CRSwNP is a common health condition in the Western world, with an estimated prevalence of 3%. Despite worldwide evidence-based treatment guidelines such as the European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS) 2020 and the European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) chronic rhinosinusitis (CRS) pocket guide, a significant number of patients remain undiagnosed and/or uncontrolled with repeated oral corticosteroids (OCS) treatments and/or (multiple) endoscopic sinus surgeries (ESS).
    Language English
    Publishing date 2024-03-20
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-6101
    ISSN (online) 2673-6101
    DOI 10.3389/falgy.2024.1372919
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: EPOS/EUFOREA update on indication and evaluation of Biologics in Chronic Rhinosinusitis with Nasal Polyps 2023.

    Fokkens, W J / Viskens, A-S / Backer, V / Conti, D / De Corso, E / Gevaert, P / Scadding, G K / Wagemann, M / Bernal-Sprekelsen, M / Chaker, A / Heffler, E / Han, J K / Van Staeyen, E / Hopkins, C / Mullol, J / Peters, A / Reitsma, S / Senior, B A / Hellings, P W

    Rhinology

    2023  Volume 61, Issue 3, Page(s) 194–202

    Abstract: Severe chronic rhinosinusitis with nasal polyps (CRSwNP) is a debilitating disease with a significant impact on the quality of life (QoL). It is typically characterized by a type 2 inflammatory reaction and by comorbidities such as asthma, allergies and ... ...

    Abstract Severe chronic rhinosinusitis with nasal polyps (CRSwNP) is a debilitating disease with a significant impact on the quality of life (QoL). It is typically characterized by a type 2 inflammatory reaction and by comorbidities such as asthma, allergies and NSAID-Exacerbated Respiratory Disease (N-ERD). Here, the European Forum for Research and Education in Allergy and Airway diseases discusses practical guidelines for patients on biologic treatment. Criteria for the selection of patients who would benefit from biologics were updated. Guidelines are proposed concerning the monitoring of the drug effects that provide recognition of responders to the therapy and, subsequently, the decision about continuation, switching or discontinuation of a biologic. Furthermore, gaps in the current knowledge and unmet needs were discussed.
    MeSH term(s) Humans ; Nasal Polyps/drug therapy ; Quality of Life ; Rhinitis/drug therapy ; Sinusitis/therapy ; Biological Products/therapeutic use ; Chronic Disease
    Chemical Substances Biological Products
    Language English
    Publishing date 2023-03-31
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 80336-4
    ISSN 0300-0729
    ISSN 0300-0729
    DOI 10.4193/Rhin22.489
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: A EUFOREA comment on a lost comorbidity of asthma.

    Conti, Diego M / Hellings, Peter W / Diamant, Zuzana / Bjermer, Leif / Jesenak, Milos / Backer, Vibeke / Fokkens, Wytske / Lau, Susanne / Van Staeyen, Elizabeth / Scadding, Glenis K

    Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology

    2023  Volume 19, Issue 1, Page(s) 56

    Abstract: Epidemiology of comorbidities and their association with asthma control" (Tomisa, G., Horváth, A., Sánta, B. et al. Epidemiology of comorbidities and their association with asthma control. Allergy Asthma Clin Immunol 17, 95 (2021). https://doi.org/10 ... ...

    Abstract "Epidemiology of comorbidities and their association with asthma control" (Tomisa, G., Horváth, A., Sánta, B. et al. Epidemiology of comorbidities and their association with asthma control. Allergy Asthma Clin Immunol 17, 95 (2021). https://doi.org/10.1186/s13223-021-00598-3 ) is an interesting paper reflecting data collection from more than 12,000 asthmatic patients in Hungary regarding their condition and associated comorbidities. We found it valuable that the paper provides an overview of asthma comorbidities not usually considered in similar reports. Nevertheless, we believe that chronic rhinosinusitis (CRS) with or without nasal polyps (CRSwNP or CRSsNP) should have been listed due to its high incidence and prevalence, its association with asthma which is also endorsed in both GINA and EPOS, as well as in several peer-reviewed scientific papers, and to reflect the role of this comorbidity in poor control and a most severe presentation of asthma for the patient. Consequently, several targeted therapies (especially monoclonal antibodies) used for several years in severe forms of asthma are now indicated also for the effective treatment of nasal polyps.
    Language English
    Publishing date 2023-06-30
    Publishing country England
    Document type Letter
    ZDB-ID 2434973-2
    ISSN 1710-1492 ; 1710-1484
    ISSN (online) 1710-1492
    ISSN 1710-1484
    DOI 10.1186/s13223-023-00816-0
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    Zs.A 6713: Show issues Location:
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  4. Article ; Online: White Paper on European Patient Needs and Suggestions on Chronic Type 2 Inflammation of Airways and Skin by EUFOREA.

    De Prins, Louise / Raap, Ulrike / Mueller, Tara / Schmid-Grendelmeier, Peter / Haase, Christiane H / Backer, Vibeke / Fokkens, Wytske / Benoist, Linda B / Prokopakis, Emmanuel / Hopkins, Claire / Claeys, Nele / Teeling, Thijs / Cypers, Lindsay / Cools, Leen / Bjermer, Leif H / Diamant, Zuzana / Wahn, Ulrich / Scadding, Glenis / Bachert, Claus /
    Patel, Sunni R / Van Staeyen, Elizabeth / Hellings, Peter

    Frontiers in allergy

    2022  Volume 3, Page(s) 889221

    Abstract: Background: Type 2 inflammation underlies the chronicity of disease in subgroups of patients with asthma, chronic rhinosinusitis with nasal polyps (CRSwNP) and atopic dermatitis (AD), that often co-exist. Although several studies have investigated the ... ...

    Abstract Background: Type 2 inflammation underlies the chronicity of disease in subgroups of patients with asthma, chronic rhinosinusitis with nasal polyps (CRSwNP) and atopic dermatitis (AD), that often co-exist. Although several studies have investigated the unmet needs of asthma, AD and CRSwNP as such, little is known about the similarities and differences in experiences and perspectives of the current management of patients with comorbid Type 2 inflammatory diseases.
    Aims: To improve insight into the common and organ-specific needs of patients with Type 2 inflammation and comorbidities, allowing the formulation of recommendations to better address these needs in the future.
    Methodology: This qualitative study was conducted between July 2021 and December 2021 using semi-structured face-to-face or telephone interviews with patients suffering from year-long severe chronic Type 2 inflammation and at least one co-morbid inflammatory condition. Seven participating academic centers in Europe interviewed asthma (Copenhagen and Leuven), CRSwNP (London, Amsterdam and Crete) and/or AD (Oldenburg and Zurich) patients on patient characteristics, disease severity, shortcomings of current care pathways and suggestions for improvement of care. Transcripts were analyzed using an inductive thematic analysis approach.
    Results: Eighty-one patients with severe Type 2 inflammation and comorbidities were interviewed. Similar needs were recognized by patients with Type 2 inflammation, with both a lack of coordination in care and a lack of a real cure reported as being most frustrating. However, several needs are specific to asthma, CRSwNP and AD. Suggestions for improvement of care were generic across diseases, such as the implementation of a multidisciplinary approach, the improved facilitation of access to better treatments, the increase of general awareness on disease burden, and better educational programs for healthcare providers and patients. Of note, patients with CRSwNP also stated the need for alternatives to sinus surgery, whereas patients with asthma requested better medical care to prevent exacerbations and patients with AD would warmly welcome the reimbursement of emollients.
    Conclusion: Patients with asthma, CRSwNP and AD have shared unmet needs that need to be addressed by physicians, the academic community and health policy makers. This survey provides unique recommendations made by patients for the implementation of better care.
    Language English
    Publishing date 2022-06-02
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-6101
    ISSN (online) 2673-6101
    DOI 10.3389/falgy.2022.889221
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Corrigendum on: White paper on European patient needs and suggestions on chronic type 2 inflammation of airways and skin by EUFOREA.

    De Prins, Louise / Raap, Ulrike / Mueller, Tara / Schmid-Grendelmeier, Peter / Haase, Christiane H / Backer, Vibeke / Fokkens, Wytske / Benoist, Linda B / Prokopakis, Emmanuel / Doulaptsi, Maria / Hopkins, Claire / Claeys, Nele / Teeling, Thijs / Cypers, Lindsay / Cools, Leen / Bjermer, Leif H / Diamant, Zuzana / Wahn, Ulrich / Scadding, Glenis /
    Bachert, Claus / Walther, Peter / Patel, Sunni R / Van Staeyen, Elizabeth / Hellings, Peter

    Frontiers in allergy

    2022  Volume 3, Page(s) 1001078

    Abstract: This corrects the article DOI: 10.3389/falgy.2022.889221.]. ...

    Abstract [This corrects the article DOI: 10.3389/falgy.2022.889221.].
    Language English
    Publishing date 2022-09-09
    Publishing country Switzerland
    Document type Published Erratum
    ISSN 2673-6101
    ISSN (online) 2673-6101
    DOI 10.3389/falgy.2022.1001078
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  6. Article ; Online: EUFOREA pocket guide on the diagnosis and management of asthma: An educational and practical tool for general practitioners, non-respiratory physicians, paramedics and patients.

    Diamant, Zuzana / Jesenak, Milos / Hanania, Nicola A / Heaney, Liam G / Djukanovic, Ratko / Ryan, Dermot / Quirce, Santiago / Backer, Vibeke / Gaga, Mina / Pavord, Ian / Antolín-Amérigo, Darío / Assaf, Sara / Bakakos, Petros / Bobcakova, Anna / Busse, William / Kappen, Jasper / Loukides, Stelios / van Maaren, Maurits / Panzner, Petr /
    Pite, Helena / Spanevello, Antonio / Stenberg, Henning / Striz, Ilja / Thio, Boony / Vasakova, Martina Koziar / Conti, Diego / Fokkens, Wytske / Lau, Susanne / Scadding, Glenis K / Van Staeyen, Elizabeth / Hellings, Peter W / Bjermer, Leif

    Respiratory medicine

    2023  Volume 218, Page(s) 107361

    MeSH term(s) Humans ; General Practitioners ; Paramedics ; Asthma/diagnosis ; Asthma/therapy ; Educational Status ; Patients
    Language English
    Publishing date 2023-07-28
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1003348-8
    ISSN 1532-3064 ; 0954-6111
    ISSN (online) 1532-3064
    ISSN 0954-6111
    DOI 10.1016/j.rmed.2023.107361
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui III Zs.19: Show issues Location:
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  7. Article: The EUFOREA pocket guide for chronic rhinosinusitis.

    Hellings, P W / Fokkens, W J / Orlandi, R / Adriaensen, G F / Alobid, I / Baroody, F M / Bjermer, L / Senior, B A / Cervin, A / Cohen, N A / Constantinidis, J / De Corso, E / Desrosiers, M / Diamant, Z / Douglas, R G / Gane, S / Gevaert, P / Han, J K / Harvey, R J /
    Hopkins, C / Kern, R C / Landis, B N / Lee, J T / Lee, S E / Leunig, A / Lund, V J / Bernal-Sprekelsen, M / Mullol, J / Philpott, C / Prokopakis, E / Reitsma, S / Ryan, D / Salmi, S / Scadding, G / Schlosser, R J / Steinsvik, A / Tomazic, P V / Van Staeyen, E / Van Zele, T / Vanderveken, O / Viskens, A-S / Conti, D / Wagenmann, M

    Rhinology

    2022  Volume 61, Issue 1, Page(s) 85–89

    Abstract: Chronic rhinosinusitis (CRS) is known to affect around 5 % of the total population, with major impact on the quality of life of those severely affected (1). Despite a substantial burden on individuals, society and health economies, CRS often remains ... ...

    Abstract Chronic rhinosinusitis (CRS) is known to affect around 5 % of the total population, with major impact on the quality of life of those severely affected (1). Despite a substantial burden on individuals, society and health economies, CRS often remains underdiagnosed, under-estimated and under-treated (2). International guidelines like the European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS) (3) and the International Consensus statement on Allergy and Rhinology: Rhinosinusitis 2021 (ICAR) (4) offer physicians insight into the recommended treatment options for CRS, with an overview of effective strategies and guidance of diagnosis and care throughout the disease journey of CRS.
    MeSH term(s) Humans ; Rhinitis/diagnosis ; Rhinitis/therapy ; Rhinitis/epidemiology ; Quality of Life ; Sinusitis/diagnosis ; Sinusitis/therapy ; Sinusitis/epidemiology ; Hypersensitivity ; Chronic Disease ; Nasal Polyps/diagnosis ; Nasal Polyps/therapy
    Language English
    Publishing date 2022-12-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 80336-4
    ISSN 0300-0729
    ISSN 0300-0729
    DOI 10.4193/Rhin22.344
    Database MEDical Literature Analysis and Retrieval System OnLINE

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