LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Your last searches

  1. AU="Van Tuijn, Charlotte F J"
  2. AU="Cooper, Timothy"

Search results

Result 1 - 10 of total 19

Search options

  1. Article ; Online: Prevalence of autoimmune diseases in patients with sickle cell disease: a single center retrospective analysis.

    Tang, Man Wai / Nur, Erfan / Van Tuijn, Charlotte F J / Biemond, Bart J

    Haematologica

    2024  

    Abstract: Not available. ...

    Abstract Not available.
    Language English
    Publishing date 2024-03-28
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2333-4
    ISSN 1592-8721 ; 0017-6567 ; 0390-6078
    ISSN (online) 1592-8721
    ISSN 0017-6567 ; 0390-6078
    DOI 10.3324/haematol.2023.284552
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: The association between renal function decline and disease severity in sickle cell disease.

    Gaartman, Aafke E / van Tuijn, Charlotte F J / Nur, Erfan / Vogt, Liffert / Biemond, Bart J

    American journal of hematology

    2023  Volume 98, Issue 5, Page(s) E95–E97

    MeSH term(s) Humans ; Anemia, Sickle Cell/complications ; Patient Acuity ; Kidney/physiology
    Language English
    Publishing date 2023-02-06
    Publishing country United States
    Document type Letter
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.26860
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Azathioprine/hydroxyurea preconditioning prior to nonmyeloablative matched sibling donor hematopoietic stem cell transplantation in adults with sickle cell disease: A prospective observational cohort study.

    Dovern, Elisabeth / Aydin, Mesire / Hazenberg, Mette D / Tang, Man Wai / Suijk, Elisabeth M / Hoogendoorn, Gerianne M / Van Tuijn, Charlotte F J / Kerkhoffs, Jean-Louis / Rutten, Caroline E / Zeerleder, Sacha S / de la Fuente, Josu / Biemond, Bart J / Nur, Erfan

    American journal of hematology

    2024  

    Abstract: Nonmyeloablative, matched sibling donor hematopoietic stem cell transplantation with alemtuzumab/total body irradiation (TBI) conditioning is a curative therapy with low toxicity for adults with sickle cell disease (SCD). However, relatively low donor ... ...

    Abstract Nonmyeloablative, matched sibling donor hematopoietic stem cell transplantation with alemtuzumab/total body irradiation (TBI) conditioning is a curative therapy with low toxicity for adults with sickle cell disease (SCD). However, relatively low donor chimerism levels and graft rejection remain important challenges. We hypothesized that adding azathioprine/hydroxyurea preconditioning will improve donor chimerism levels and reduce graft failure rate. In this prospective cohort study, we enrolled consecutive adult patients with SCD undergoing matched sibling donor transplantation at the Amsterdam UMC. Patients received azathioprine 150 mg/day and hydroxyurea 25 mg/kg/day for 3 months prior to alemtuzumab 1 mg/kg and 300 cGy TBI conditioning. Twenty patients with SCD (median age 26 years [range 19-49], 13 females) were transplanted. Median follow-up was 46.0 months (IQR 21.8-57.9). One-year overall survival and event-free survival (graft failure or death) were both 95% (95% confidence interval 86-100). Mean donor myeloid and T-cell chimerism 1-year post-transplant were 95.2% (SD ±10.6) and 67.3% (±15.3), respectively. One patient (5%) experienced graft failure without autologous regeneration, resulting in infections and death. All other patients had a corrected SCD phenotype and were able to discontinue sirolimus. Three patients were successfully treated with alemtuzumab (1 mg/kg) after the transplant because of declining donor chimerism and cytopenias to revert impending graft rejection. Toxicity was mostly related to sirolimus and alemtuzumab. One patient developed steroid-responsive grade II intestinal acute graft-versus-host disease. Collectively, preconditioning with azathioprine/hydroxyurea prior to nonmyeloablative matched sibling donor transplantation resulted in excellent event-free survival and robust donor T-cell chimerism, enabling the successful withdrawal of sirolimus. ClinicalTrials.gov: NCT05249452.
    Language English
    Publishing date 2024-05-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.27360
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Vaso-occlusive crisis and acute chest syndrome in sickle cell disease due to 2019 novel coronavirus disease (COVID-19).

    Nur, Erfan / Gaartman, Aafke E / van Tuijn, Charlotte F J / Tang, Man Wai / Biemond, Bart J

    American journal of hematology

    2020  Volume 95, Issue 6, Page(s) 725–726

    MeSH term(s) Acute Chest Syndrome/complications ; Acute Chest Syndrome/diagnosis ; Acute Chest Syndrome/physiopathology ; Adult ; Anemia, Sickle Cell/complications ; Anemia, Sickle Cell/physiopathology ; Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/physiopathology ; Diagnosis, Differential ; Female ; Humans ; Male ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/physiopathology ; SARS-CoV-2 ; Tomography, X-Ray Computed
    Keywords covid19
    Language English
    Publishing date 2020-04-21
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.25821
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Incentive spirometry to prevent acute chest syndrome in adults with sickle cell disease; a randomized controlled trial.

    van Tuijn, Charlotte F J / Gaartman, Aafke E / Nur, Erfan / Rijneveld, Anita W / Biemond, Bart J

    American journal of hematology

    2020  Volume 95, Issue 7, Page(s) E160–E163

    MeSH term(s) Acute Chest Syndrome/physiopathology ; Acute Chest Syndrome/prevention & control ; Adult ; Humans ; Male ; Spirometry
    Keywords covid19
    Language English
    Publishing date 2020-05-01
    Publishing country United States
    Document type Letter ; Multicenter Study ; Randomized Controlled Trial
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.25805
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: A multimodal pain protocol for treatment of vaso-occlusive crisis in patients with sickle cell disease: Implementation and evaluation.

    Admiraal, Manouk / van Daalen, Jonathan / Ritt, Michael W J / Dekker, Joost / van Tuijn, Charlotte F J / Nur, Erfan / Hollmann, Markus W / Hermanns, Henning / Hermanides, Jeroen / Biemond, Bart J

    European journal of haematology

    2023  Volume 111, Issue 3, Page(s) 382–390

    Abstract: Objectives: Pain management during a vaso-occlusive crisis (VOC) for patients with sickle cell disease (SCD) remains a major challenge and strongly depends on opioids. We developed a multimodality pain protocol for rapid, opioid-sparing pain treatment ... ...

    Abstract Objectives: Pain management during a vaso-occlusive crisis (VOC) for patients with sickle cell disease (SCD) remains a major challenge and strongly depends on opioids. We developed a multimodality pain protocol for rapid, opioid-sparing pain treatment of VOC and evaluated its feasibility.
    Methods: Patients were included for evaluation if they were ≥18 years, diagnosed with SCD and visited the emergency department (ED) because of VOC between July 2018 and December 2020. Primary evaluation outcome was the feasibility of multimodal pain analgesia (i.e., the use of at least two analgesics with different underlying mechanisms of action).
    Results: A total of 131 SCD patients visited the ED because of VOC with a total of 550 ED presentations, of which 377 were eventually hospitalised. A total of 508 (92.4%) ED presentations and 374 (99.2%) hospital admissions received multimodal pain treatment. Time to first administration of an opioid was median [IQR] 34.0 [21.0-62.0] minutes.
    Conclusion: The implementation of a pain protocol using multimodal analgesia for VOC in patients with SCD appeared to be feasible and facilitated rapid administration of opioids. Controlled trials are needed to investigate the effectiveness of multimodal analgesia on pain and should focus on patient reported outcome measures.
    MeSH term(s) Humans ; Analgesics, Opioid/therapeutic use ; Volatile Organic Compounds ; Pain/diagnosis ; Pain/drug therapy ; Pain/etiology ; Pain Management/adverse effects ; Pain Management/methods ; Anemia, Sickle Cell/complications ; Anemia, Sickle Cell/diagnosis
    Chemical Substances Analgesics, Opioid ; Volatile Organic Compounds
    Language English
    Publishing date 2023-06-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 392482-8
    ISSN 1600-0609 ; 0902-4441
    ISSN (online) 1600-0609
    ISSN 0902-4441
    DOI 10.1111/ejh.14017
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Incidence of SARS-COV-2 infection in sickle cell patients presenting with a painful crisis: A 12-month prospective cohort study.

    Konté, Kadère / Nur, Erfan / Tang, Man Wai / Heijmans, Jarom / van Tuijn, Charlotte F J / Biemond, Bart J

    International journal of laboratory hematology

    2021  Volume 44, Issue 2, Page(s) e87–e90

    MeSH term(s) Anemia, Sickle Cell/complications ; Anemia, Sickle Cell/epidemiology ; COVID-19/epidemiology ; Humans ; Incidence ; Prospective Studies ; SARS-CoV-2
    Language English
    Publishing date 2021-10-15
    Publishing country England
    Document type Letter
    ZDB-ID 2268590-X
    ISSN 1751-553X ; 1751-5521 ; 0141-9854
    ISSN (online) 1751-553X
    ISSN 1751-5521 ; 0141-9854
    DOI 10.1111/ijlh.13739
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Changing Stress Mindset Through Stressjam: A Virtual Reality Game Using Biofeedback.

    Maarsingh, Bernard M / Bos, Jannah / Van Tuijn, Charlotte F J / Renard, Selwyn B

    Games for health journal

    2019  Volume 8, Issue 5, Page(s) 326–331

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adult ; Biofeedback, Psychology/methods ; Female ; Humans ; Male ; Middle Aged ; Psychometrics/instrumentation ; Psychometrics/methods ; Stress, Psychological/psychology ; Stress, Psychological/therapy ; Video Games/psychology ; Video Games/standards ; Virtual Reality
    Language English
    Publishing date 2019-09-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2650543-5
    ISSN 2161-7856 ; 2161-783X
    ISSN (online) 2161-7856
    ISSN 2161-783X
    DOI 10.1089/g4h.2018.0145
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Vaso-occlusive crisis and acute chest syndrome in sickle cell disease due to 2019 novel coronavirus disease (COVID-19)

    Nur, Erfan / Gaartman, Aafke E / van Tuijn, Charlotte F J / Tang, Man Wai / Biemond, Bart J

    Am J Hematol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #42166
    Database COVID19

    Kategorien

  10. Article ; Online: Prospective evaluation of chronic organ damage in adult sickle cell patients: A seven-year follow-up study.

    van Tuijn, Charlotte F J / Schimmel, Marein / van Beers, Eduard J / Nur, Erfan / Biemond, Bart J

    American journal of hematology

    2017  Volume 92, Issue 10, Page(s) E584–E590

    Abstract: Organ damage in sickle cell disease (SCD) is a crucial determinant for disease severity and prognosis. In a previous study, we analyzed the prevalence of SCD-related organ damage and complications in adult sickle cell patients. We now describe a seven- ... ...

    Abstract Organ damage in sickle cell disease (SCD) is a crucial determinant for disease severity and prognosis. In a previous study, we analyzed the prevalence of SCD-related organ damage and complications in adult sickle cell patients. We now describe a seven-year follow-up of this cohort.All patients from the primary analysis in 2006 (n = 104), were included for follow-up. Patients were screened for SCD-related organ damage and complications (microalbuminuria, renal failure, elevated tricuspid regurgitation flow velocity (TRV) (≥2.5 m/seconds), retinopathy, iron overload, cholelithiasis, avascular osteonecrosis, leg ulcers, acute chest syndrome (ACS), stroke, priapism and admissions for vaso-occlusive crises (VOC) biannually. Upon 7 years of follow-up, progression in the prevalence of avascular osteonecrosis (from 12.5% to 20.4%), renal failure (from 6.7% to 23.4%), retinopathy (from 39.7% to 53.8%) was observed in the whole group. In HbSS/HbSβ
    MeSH term(s) Adult ; Anemia, Sickle Cell/blood ; Anemia, Sickle Cell/complications ; Anemia, Sickle Cell/mortality ; Anemia, Sickle Cell/therapy ; Arterial Occlusive Diseases/epidemiology ; Arterial Occlusive Diseases/etiology ; Cholelithiasis/epidemiology ; Cholelithiasis/etiology ; Cross-Sectional Studies ; Female ; Follow-Up Studies ; Genotype ; Hospitalization/statistics & numerical data ; Humans ; Kaplan-Meier Estimate ; Kidney Diseases/epidemiology ; Kidney Diseases/etiology ; Male ; Middle Aged ; Prevalence ; Prospective Studies ; Retinal Diseases/epidemiology ; Retinal Diseases/etiology ; Tricuspid Valve Insufficiency/epidemiology ; Tricuspid Valve Insufficiency/etiology
    Language English
    Publishing date 2017-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.24855
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top