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  1. Article ; Online: Protocol of the LATFIA trial (Laser Assisted Treatment of Fistula in Ano): a multicentre, prospective, randomized controlled trial comparing fistula-tract laser closure (FiLaC™) with rectal advancement flap for high trans-sphincteric fistulas.

    Gaillard, Marie / Van den Broeck, Sylvie / Op de Beeck, Bart / Wouters, Kristien / Stijns, Jasper / Van de Putte, Dirk / Gys, Ben / Houben, Bert / Van Dessel, Els / Bislenghi, Gabriele / Komen, Niels

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2024  

    Abstract: Aim: Anal fistula is one of the most common anal diseases, affecting between 1 and 3 per 10 000 people per year. Symptoms have a potentially severe effect on a patient's quality of life. Surgery is the mainstay of treatment, aiming to cure the fistula ... ...

    Abstract Aim: Anal fistula is one of the most common anal diseases, affecting between 1 and 3 per 10 000 people per year. Symptoms have a potentially severe effect on a patient's quality of life. Surgery is the mainstay of treatment, aiming to cure the fistula and preserve anal sphincter function. Rectal advancement flap (RAF) is currently the gold standard treatment but has recurrence rates varying between 20% and 50% and might lead to disturbance of continence. The aim of the trial described in this work is to discover if the minimally invasive fistula tract laser closure (FiLaC™) technique could achieve higher healing rates and a better functional outcome than RAF.
    Method: We will perform a randomized prospective multicentre noninferiority study of the treatment of high trans-sphincteric perianal fistulas, comparing FiLaC™ with RAF in terms of fistula healing, recurrence rate, functional outcome and quality of life. Primary and secondary fistula healing will be evaluated at 26 and 52 weeks' follow-up. Quality of life will be evaluated using the SF-36 questionnaire, the Faecal Incontinence Quality of Life Scale questionnaire and the Vaizey score at 3, 6, 12 and 26 weeks postoperatively.
    Conclusion: High trans-sphincteric fistulas have a potentially severe effect on a patient's quality of life. Classical treatment with RAF is a time-consuming invasive procedure. The LATFIA trial aims to compare FiLaC™ with the gold standard treatment with RAF. In case of noninferiority, FiLaC™ treatment could be standardized as a first line treatment for high trans-sphincteric fistulas. Better conservation of the patient's anal sphincter function could possibly be obtained. Likewise, we will report on the postoperative quality of life when applying these two techniques.
    Language English
    Publishing date 2024-03-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.16951
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  2. Article: Symptomatic gastric involvement in a parastomal hernia: uncommon presentation.

    Vierstraete, Maaike / Van de Putte, Dirk / Pattyn, Piet

    Acta chirurgica Belgica

    2018  Volume 120, Issue 1, Page(s) 57–60

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Aged ; Colostomy/adverse effects ; Female ; Humans ; Incisional Hernia/diagnostic imaging ; Incisional Hernia/etiology ; Incisional Hernia/surgery ; Stomach Diseases/diagnostic imaging ; Stomach Diseases/etiology ; Stomach Diseases/surgery ; Surgical Stomas/adverse effects ; Tomography, X-Ray Computed
    Language English
    Publishing date 2018-08-14
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 210274-2
    ISSN 0001-5458
    ISSN 0001-5458
    DOI 10.1080/00015458.2018.1500800
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  3. Article: The Role of Abdominal Drain Cultures in Managing Abdominal Infections.

    De Waele, Jan J / Boelens, Jerina / Van De Putte, Dirk / Huis In 't Veld, Diana / Coenye, Tom

    Antibiotics (Basel, Switzerland)

    2022  Volume 11, Issue 5

    Abstract: Intra-abdominal infections (IAI) are common in hospitalized patients, both in and outside of the intensive care unit. Management principles include antimicrobial therapy and source control. Typically, these infections are polymicrobial, and intra- ... ...

    Abstract Intra-abdominal infections (IAI) are common in hospitalized patients, both in and outside of the intensive care unit. Management principles include antimicrobial therapy and source control. Typically, these infections are polymicrobial, and intra-operative samples will guide the targeted antimicrobial therapy. Although the use of prophylactic abdominal drains in patients undergoing abdominal surgery is decreasing, the use of drains to treat IAI, both in surgical and non-surgical strategies for abdominal infection, is increasing. In this context, samples from abdominal drains are often used to assist in antimicrobial decision making. In this narrative review, we provide an overview of the current role of abdominal drains in surgery, discuss the importance of biofilm formation in abdominal drains and the mechanisms involved, and review the clinical data on the use of sampling these drains for diagnostic purposes. We conclude that biofilm formation and the colonization of abdominal drains is common, which precludes the use of abdominal fluid to reliably diagnose IAI and identify the pathogens involved. We recommend limiting the use of drains and, when present, avoiding routine microbiological sampling.
    Language English
    Publishing date 2022-05-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics11050697
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  4. Article ; Online: Patient-reported outcomes after pelvic exenteration for colorectal cancer: A systematic review.

    Denys, Andreas / van Nieuwenhove, Yves / Van de Putte, Dirk / Pape, Eva / Pattyn, Piet / Ceelen, Wim / van Ramshorst, Gabriëlle H

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2022  Volume 24, Issue 4, Page(s) 353–368

    Abstract: Aim: Pelvic exenteration (PE) carries high morbidity. Our aim was to analyse the use of patient-reported outcome measures (PROMs) in PE patients.: Method: Search strategies were protocolized and registered in PROSPERO. PubMed, Embase, Cochrane ... ...

    Abstract Aim: Pelvic exenteration (PE) carries high morbidity. Our aim was to analyse the use of patient-reported outcome measures (PROMs) in PE patients.
    Method: Search strategies were protocolized and registered in PROSPERO. PubMed, Embase, Cochrane Library, Google Scholar, Web of Science and ClinicalTrials.gov were searched with the terms 'patient reported outcomes', 'pelvic exenteration' and 'colorectal cancer'. Studies published after 1980 reporting on PROMs for at least 10 PE patients were considered. Study selection, data extraction, rating of certainty of evidence (GRADE) and risk of bias (ROBINS-I) were performed independently by two reviewers.
    Results: Nineteen of 173 studies were included (13 retrospective, six prospective). All studies were low to very low quality, with an overall moderate/serious risk of bias. Studies included data on 878 patients with locally advanced rectal cancer (n = 344), recurrent rectal cancer (n = 411) or cancer of unknown type (n = 123). Thirteen studies used validated questionnaires, four used non-validated measures and two used both. Questionnaires included the Functional Assessment of Cancer Therapy-Colorectal questionnaire (n = 6), Short Form Health Survey (n = 6), European Organization for Research and Treatment for Cancer (EORTC) Quality of Life Questionnaire C30 (n = 6), EORTC-CR38 (n = 4), EORTC-BLM30 (n = 1), Brief Pain Inventory (n = 2), Short Form 12 (n = 1), Assessment of Quality of Life (n = 1), Short Form Six-Dimension (n = 1), the Memorial Sloan Kettering Cancer Center Sphincter Function Scale (n = 1), the Cleveland Global Quality of Life (n = 1) or other (n = 4). Timing varied between studies.
    Conclusions: Whilst the use of validated questionnaires increased over time, this study shows that there is a need for uniform use and timing of PROMs to enable multicentre studies.
    MeSH term(s) Humans ; Neoplasm Recurrence, Local/surgery ; Patient Reported Outcome Measures ; Pelvic Exenteration/methods ; Prospective Studies ; Quality of Life ; Rectal Neoplasms/surgery ; Retrospective Studies
    Language English
    Publishing date 2022-01-30
    Publishing country England
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.16028
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  5. Article ; Online: An Adolescent With Severe Abdominal Pain, An Unexpected Outcome.

    Keenswijk, Werner / Van de Putte, Dirk

    Gastroenterology

    2017  Volume 152, Issue 5, Page(s) e1–e2

    Language English
    Publishing date 2017-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2016.08.048
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  6. Article ; Online: Time Is Money in Case of a Button Battery Ingestion.

    Bosschaert, Charlotte / Van Renterghem, Katrien / Van de Putte, Dirk / Matthyssens, Lucas / Vande Velde, Saskia / De Bruyne, Pauline / De Bruyne, Ruth / Beel, Emma / Van Biervliet, Stephanie

    JPGN reports

    2022  Volume 3, Issue 4, Page(s) e259

    Abstract: Button battery (BB) ingestion is a preventable pediatric health hazard with important morbidity and mortality due to complications. We present 3 pediatric patients with a complicated course after BB ingestion and discuss current guidelines. Urgent ... ...

    Abstract Button battery (BB) ingestion is a preventable pediatric health hazard with important morbidity and mortality due to complications. We present 3 pediatric patients with a complicated course after BB ingestion and discuss current guidelines. Urgent endoscopic removal is necessary for every BB impacted in the esophagus. A new strategy before endoscopic removal is the administration of honey or sucralfate. During endoscopy, rinsing the esophageal mucosae with acetic acid can neutralize the alkalic environment and prevent late complications. Prevention of ingestion needs to be pursued by increasing awareness and changing legislation of packaging of BB.
    Language English
    Publishing date 2022-10-20
    Publishing country United States
    Document type Case Reports
    ISSN 2691-171X
    ISSN (online) 2691-171X
    DOI 10.1097/PG9.0000000000000259
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  7. Article ; Online: Interprofessional perspectives on care for patients with low anterior resection syndrome: A qualitative study.

    Pape, Eva / Van Haver, Dora / Lievrouw, An / Van Nieuwenhove, Yves / Van De Putte, Dirk / Van Ongeval, Johan / Rogge, Sofie / Van Hecke, Ann

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2022  Volume 24, Issue 9, Page(s) 1032–1039

    Abstract: Aim: Many patients are confronted with low anterior resection syndrome after rectal surgery. The perspectives of both healthcare professionals and patients on the impact of bowel problems may differ. This study aimed to explore experiences of healthcare ...

    Abstract Aim: Many patients are confronted with low anterior resection syndrome after rectal surgery. The perspectives of both healthcare professionals and patients on the impact of bowel problems may differ. This study aimed to explore experiences of healthcare professionals on how to provide, organise and optimise care for patients with low anterior resection syndrome from an interprofessional perspective.
    Methods: An explorative qualitative design was used. Healthcare professionals were recruited in October 2018 in one general teaching hospital and one university hospital. Twenty one healthcare professionals from different professions caring for patients with low anterior resection syndrome were included in three focus group interviews.
    Results: Healthcare professionals confirmed a lack of focus on patients who are confronted with low anterior resection syndrome and stated a need for a standardised approach of care. Additionally, three levels for care optimization emerged from the data: information before surgery with strong emphasis on the timing of informing, counselling of patients when confronted with low anterior resection syndrome and organisation of care.
    Conclusions: Healthcare professionals find it important to adopt the moment and amount of information to the coping mechanism and timing of the trajectory. Counselling and follow-up of patients with LARS should be organised proactively and should not remain restricted to pharmacological and nutritional advice. A possible strategy is to develop and implement late effects nurse-led clinics coordinated by the clinical nurse specialist.
    MeSH term(s) Digestive System Surgical Procedures ; Humans ; Postoperative Complications ; Quality of Life ; Rectal Diseases ; Rectal Neoplasms/surgery ; Syndrome
    Language English
    Publishing date 2022-05-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.16145
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  8. Article ; Online: Thunderbeat-Assisted Hemorrhoidectomy in Symptomatic Prolapsing Hemorrhoids: A Pilot Trial.

    Heyerick, Lander / Van de Putte, Dirk / De Visschere, Marieke / Pattyn, Piet / Tate, David J / Van Vlierberghe, Hans / De Looze, Danny

    Surgical innovation

    2020  Volume 27, Issue 3, Page(s) 311–312

    MeSH term(s) Hemorrhoidectomy/adverse effects ; Hemorrhoids/surgery ; Humans ; Network Meta-Analysis ; Pain, Postoperative ; Pilot Projects ; Surgical Stapling
    Language English
    Publishing date 2020-03-07
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2182571-3
    ISSN 1553-3514 ; 1553-3506
    ISSN (online) 1553-3514
    ISSN 1553-3506
    DOI 10.1177/1553350620908381
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  9. Article: Primary care providers' knowledge about the therapeutic management of refractory pelvic floor dysfunctions in Flanders, Belgium: a cross-sectional study.

    Ghijselings, Lynn / Pauwaert, Kim / Verla, Wesley / Beeckman, Dimitri / Van de Putte, Dirk / Pattyn, Piet / Everaert, Karel

    Acta chirurgica Belgica

    2020  Volume 121, Issue 6, Page(s) 386–393

    Abstract: Background: Pelvic floor dysfunctions (PFD) are prevalent conditions in primary care practice. Basic knowledge of second-line therapies among primary care providers (PCPs) is indispensable to well-inform refractory patients and improve their access to ... ...

    Abstract Background: Pelvic floor dysfunctions (PFD) are prevalent conditions in primary care practice. Basic knowledge of second-line therapies among primary care providers (PCPs) is indispensable to well-inform refractory patients and improve their access to specialized care.
    Objectives: Getting insight into the extent of knowledge about second-line therapies for refractory PFD among PCPs in Flanders, Belgium.
    Methods: From January to March 2019 Flemish PCPs participated in the OptiLUTS trial - Part A (EC/2018/0244), by the completion of a 22-item online Dutch questionnaire. Prevalence of PCPs having awareness about sacral neuromodulation (SNM), intradetrusor botulinum toxin injections (BTX) and percutaneous tibial nerve stimulation (PTNS) was explored. Descriptive statistics, univariate analyses, and multiple logistic regression analyses were performed.
    Results: Sixty PCPs, 55% GPs, 45% GP trainees, median age 29 years, participated. Respectively, 90, 73 and 5% had ever heard about BTX, SNM and PTNS. The profession was an independent predictive factor for never having heard of SNM therapy, GPs being more likely to have a lack of knowledge than trainees (OR = 29, 95%CI [1.9-442.5]). Ninety-three percent want to learn more about these therapies.
    Conclusion: There is a margin for improvement in the knowledge of PCPs regarding therapies for refractory PFD. Awareness among PCPs should be increased for the optimization of patient care.
    MeSH term(s) Adult ; Belgium ; Cross-Sectional Studies ; Humans ; Pelvic Floor ; Primary Health Care ; Treatment Outcome
    Language English
    Publishing date 2020-07-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 210274-2
    ISSN 0001-5458
    ISSN 0001-5458
    DOI 10.1080/00015458.2020.1794338
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  10. Article: High post-operative pain scores despite multimodal analgesia in ambulatory anorectal surgery: a prospective cohort study.

    Ceulemans, Aline / De Looze, Danny / Van de Putte, Dirk / Stiers, Eline / Coppens, Marc

    Acta chirurgica Belgica

    2018  Volume 119, Issue 4, Page(s) 224–230

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Adult ; Aged ; Ambulatory Surgical Procedures ; Anal Canal/surgery ; Analgesia/methods ; Cohort Studies ; Digestive System Surgical Procedures/methods ; Female ; Humans ; Male ; Middle Aged ; Pain Measurement ; Pain, Postoperative/diagnosis ; Prospective Studies ; Rectum/surgery ; Young Adult
    Language English
    Publishing date 2018-09-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 210274-2
    ISSN 0001-5458
    ISSN 0001-5458
    DOI 10.1080/00015458.2018.1500802
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