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  1. Article: Désensibilisation dans l’asthme et la rhinoconjonctivite allergiques : mise au point.

    Beniada, Camille / Vandenberghe-Dürr, Sophie

    Revue medicale suisse

    2023  Volume 19, Issue 821, Page(s) 658–662

    Abstract: Allergenic immunotherapy consists of repeated administration of allergenic extracts to which an individual is allergic. It is currently the only treatment that modifies the course of allergic disease and induces short- as well as long-term remission of ... ...

    Title translation Update on allergenic immunotherapy for asthma and rhinoconjunctivitis.
    Abstract Allergenic immunotherapy consists of repeated administration of allergenic extracts to which an individual is allergic. It is currently the only treatment that modifies the course of allergic disease and induces short- as well as long-term remission of symptoms. Two formulations are currently available: subcutaneous immunotherapy (SCIT) or sublingual immunotherapy (SLIT), with comparable efficacy. In specific situations, it can be used in combination with the new approved biologic therapies for asthma to improve tolerance of immunotherapy.
    MeSH term(s) Humans ; Injections, Subcutaneous ; Desensitization, Immunologic ; Asthma/therapy ; Hypersensitivity/therapy ; Sublingual Immunotherapy ; Allergens ; Immunotherapy ; Rhinitis, Allergic
    Chemical Substances Allergens
    Language French
    Publishing date 2023-04-05
    Publishing country Switzerland
    Document type English Abstract ; Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    DOI 10.53738/REVMED.2023.19.821.658
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Antihistaminiques : une histoire sans fin.

    Vandenberghe-Dürr, Sophie / Harr, Thomas / Vandenberghe, Frederik

    Revue medicale suisse

    2024  Volume 20, Issue 868, Page(s) 711–719

    Abstract: Histamine is responsible for many processes mediated by different receptors expressed on a variety of cells. The discovery of the first H1 antihistamines in the 1940s led to the development of numerous H1 and H2 antagonists with a broad application in ... ...

    Title translation Antihistamines : An ongoing narrative.
    Abstract Histamine is responsible for many processes mediated by different receptors expressed on a variety of cells. The discovery of the first H1 antihistamines in the 1940s led to the development of numerous H1 and H2 antagonists with a broad application in many indications. The recent identification of two new histamine receptors (H3, H4) in the 1980s and 2000s led to the market authorization in Switzerland of new drugs since 2018. The purpose of this review is to provide a brief overview of the physiology of histamine, the recent development of new compounds in this field, antihistamine drug indications and relevant side effects.
    MeSH term(s) Humans ; Histamine ; Histamine Antagonists/adverse effects ; Narration ; Switzerland
    Chemical Substances Histamine (820484N8I3) ; Histamine Antagonists
    Language French
    Publishing date 2024-04-03
    Publishing country Switzerland
    Document type Review ; English Abstract ; Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    DOI 10.53738/REVMED.2024.20.868.711
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Nouveaux outils dans les hypersensibilités alimentaires : par-delà les prick tests et IgE spécifiques.

    Vandenberghe-Durr, Sophie / Caubet, Jean-Christoph / Spoerl, David

    Revue medicale suisse

    2021  Volume 17, Issue 733, Page(s) 670–674

    Abstract: Food hypersensitivity represents a group of adverse immunological reactions linked to food ingestions such as anaphylaxis or eosinophilic esophagitis. Identification of the responsible food is currently based on a detailed history and complementary exams, ...

    Title translation New tools in the diagnosis of food hypersensitivity reactions: beyond IgE and prick testing.
    Abstract Food hypersensitivity represents a group of adverse immunological reactions linked to food ingestions such as anaphylaxis or eosinophilic esophagitis. Identification of the responsible food is currently based on a detailed history and complementary exams, mostly prick testing and assessment of serum specific IgE, either by ImmunoCAP or multiplex assay. Other skin and laboratory tools such as functional in vitro or patch testing are currently not validated although some show promising results in the field of food allergy. This article presents the different diagnostic procedures that are commonly and less commonly used in the workup of food allergies and their potential for future use in the workup of food-induced hypersensitivity reactions. Non-immunological reactions, rare entities (Heiner syndrome) and celiac disease will not be addressed in this review.
    MeSH term(s) Allergens ; Anaphylaxis ; Food ; Food Hypersensitivity/diagnosis ; Humans ; Immunoglobulin E ; Skin Tests
    Chemical Substances Allergens ; Immunoglobulin E (37341-29-0)
    Language French
    Publishing date 2021-04-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Syndrome de Widal : manifestations cliniques, physiopathologie et avancées thérapeutiques.

    Vandenberghe-Dürr, Sophie / Landis, Basile Nicolas / Jandus, Peter

    Revue medicale suisse

    2020  Volume 16, Issue 689, Page(s) 694–697

    Abstract: NSAID-Exacerbated respiratory disease (also known as Samter's or Widal's triad, aspirin-exacerbated respiratory disease) is characte- rized by asthma, nasal polyposis and hypersensitivity to NSAIDs. The pathogenesis of this chronic inflammation arises ... ...

    Title translation Widal's triad : clinical manifestations, pathophysiology and therapeutic advances.
    Abstract NSAID-Exacerbated respiratory disease (also known as Samter's or Widal's triad, aspirin-exacerbated respiratory disease) is characte- rized by asthma, nasal polyposis and hypersensitivity to NSAIDs. The pathogenesis of this chronic inflammation arises from an imbalance in arachidonic acid metabolism, leading to an increase in pro- inflammatory cysteinyl-leukotrienes. The treatment is based on drug management of asthma and polyps and, in advanced situations, surgical management of polyposis. Monoclonal antibodies have shown promising results in the further medical treatment of this entity.
    MeSH term(s) Anti-Inflammatory Agents, Non-Steroidal/adverse effects ; Anti-Inflammatory Agents, Non-Steroidal/immunology ; Aspirin/adverse effects ; Aspirin/immunology ; Asthma/chemically induced ; Drug Hypersensitivity ; Humans ; Nasal Polyps/chemically induced ; Sinusitis/chemically induced
    Chemical Substances Anti-Inflammatory Agents, Non-Steroidal ; Aspirin (R16CO5Y76E)
    Language French
    Publishing date 2020-04-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Human neutrophils drive skin autoinflammation by releasing interleukin (IL)-26.

    Baldo, Alessia / Di Domizio, Jeremy / Yatim, Ahmad / Vandenberghe-Dürr, Sophie / Jenelten, Raphael / Fries, Anissa / Grizzetti, Lorenzo / Kuonen, François / Paul, Carle / Modlin, Robert L / Conrad, Curdin / Gilliet, Michel

    The Journal of experimental medicine

    2024  Volume 221, Issue 5

    Abstract: Autoinflammation is a sterile inflammatory process resulting from increased neutrophil infiltration and overexpression of IL-1 cytokines. The factors that trigger these events are, however, poorly understood. By investigating pustular forms of psoriasis, ...

    Abstract Autoinflammation is a sterile inflammatory process resulting from increased neutrophil infiltration and overexpression of IL-1 cytokines. The factors that trigger these events are, however, poorly understood. By investigating pustular forms of psoriasis, we show that human neutrophils constitutively express IL-26 and abundantly release it from granular stores upon activation. In pustular psoriasis, neutrophil-derived IL-26 drives the pathogenic autoinflammation process by inducing the expression of IL-1 cytokines and chemokines that further recruit neutrophils. This occurs via activation of IL-26R in keratinocytes and via the formation of complexes between IL-26 and microbiota DNA, which trigger TLR9 activation of neutrophils. Thus our findings identify neutrophils as an important source of IL-26 and point to IL-26 as the key link between neutrophils and a self-sustaining autoinflammation loop in pustular psoriasis.
    MeSH term(s) Humans ; Neutrophils ; Psoriasis ; Interleukins ; Cytokines ; Interleukin-1
    Chemical Substances Interleukins ; Cytokines ; Interleukin-1
    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 218343-2
    ISSN 1540-9538 ; 0022-1007
    ISSN (online) 1540-9538
    ISSN 0022-1007
    DOI 10.1084/jem.20231464
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Proposition de prise en charge de l’« allergie à la pénicilline » en médecine interne et de premier recours.

    Vandenberghe-Dürr, Sophie / Jandus, Peter / Serratrice, Jacques / Harr, Thomas

    Revue medicale suisse

    2020  Volume 16, Issue 678, Page(s) 138–142

    Abstract: Penicillin allergy » is a common finding in patient's medical files (up to 10 %). Although it is important not to neglect such records (due to the serious and life-threatening reactions an allergic patient may suffer from), most of the time these ... ...

    Title translation A first-line guide to the evaluation of « Penicillin Allergy » in general medical practice.
    Abstract « Penicillin allergy » is a common finding in patient's medical files (up to 10 %). Although it is important not to neglect such records (due to the serious and life-threatening reactions an allergic patient may suffer from), most of the time these reported notions of allergy are wrong and lead to the unfortunate avoidance of all betalactamins. This in turn leads to increased risks of antibiotic resistance and increased health costs. This review aims to summarize the current knowledge on penicillin allergy epidemiologic data and proposes a first-line guide for general practitioners to the evaluation of the patient with a history of « penicillin allergy ».
    MeSH term(s) Anti-Bacterial Agents/adverse effects ; Drug Hypersensitivity ; Humans ; Penicillins/adverse effects
    Chemical Substances Anti-Bacterial Agents ; Penicillins
    Language French
    Publishing date 2020-01-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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