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Article ; Online: Szeklers’ Aspirations for Autonomy

Varga Szilvia

Acta Universitatis Sapientiae: European and Regional Studies, Vol 20, Iss 1, Pp 109-

Unconstitutionality or Lack of Political Will?

2021 Volume 112

Keywords	Political science ; J
Language	English
Publishing date	2021-12-01T00:00:00Z
Publisher	Sciendo
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Online Assessment of Morphological Awareness in Grades 2-4: Its Development and Relation to Reading Comprehension.

Varga, Szilvia / Pásztor, Attila / Stekács, János

Journal of Intelligence

2022 Volume 10, Issue 3

Abstract: The aims of the study are to construct an online instrument to assess different aspects of morphological awareness and to examine its development and its relation to reading comprehension in grades 2-4 in Hungarian children. Altogether, 4134 students ... ...

Abstract	The aims of the study are to construct an online instrument to assess different aspects of morphological awareness and to examine its development and its relation to reading comprehension in grades 2-4 in Hungarian children. Altogether, 4134 students were tested. The online test evaluated inflectional, derivational, and compound morphological skills with five subtests. The instrument proved to be reliable. CFA examinations revealed that the five subtests were empirically distinguishable dimensions. Inflectional, derivational, and compound morphology as the three main dimensions of morphological awareness were also empirically supported by our data. Morphological awareness skills improved significantly and developed in parallel with reading skills throughout grades 2-4. The increase in the development of morphological awareness from grade 2 to grade 3 tends to be faster than the growth between grade 3 and 4. Positive moderate correlations were found between morphological skills and reading comprehension and the relationships seem to be stable throughout the three grades. The most significant predictor of reading comprehension is the Affix Identification for Nonwords subtest. Our study showed that morphological awareness could be assessed efficiently through online media and drew attention to the importance of morphological awareness in the development of reading comprehension and linguistic intelligence.
Language	English
Publishing date	2022-07-25
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2721035-2
ISSN	2079-3200 ; 2079-3200
ISSN (online)	2079-3200
ISSN	2079-3200
DOI	10.3390/jintelligence10030047
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Article ; Online: Daganatos nőbetegek termékenységének megőrzése.

Vesztergom, Dóra / Nánássy, László / Polgár, Csaba / Krádi, Anna / Rosta, Viktória / Varga, Szilvia / Novák, Zoltán

Orvosi hetilap

2023 Volume 164, Issue 28, Page(s) 1094–1101

Abstract: The incidence of cancer increases with age and as family planning is being delayed, there is a growing number of cancer patients whose fertility may be affected by oncological treatments. International guidelines recommend that all reproductive age ... ...

Title translation	Fertility preservation in female cancer patients.
Abstract	The incidence of cancer increases with age and as family planning is being delayed, there is a growing number of cancer patients whose fertility may be affected by oncological treatments. International guidelines recommend that all reproductive age cancer patients, including adolescent patients, should be referred for fertility preservation consultation, and if necessary, fertility preservation procedures should be performed. Fertility preservation enables cancer survivors to offer a chance for biological parenthood after recovery. In this review, the gonadotoxic effects of oncological therapies and the fertility preservation possibilities for female cancer patients based on international recommendations and literature are discussed. Our next review will provide detailed information on the special fertility preservation possibilities for different cancer types. The two reviews may help to elaborate a national guidance. Orv Hetil. 2023; 164(28): 1094-1101.
MeSH term(s)	Adolescent ; Humans ; Female ; Fertility Preservation/methods ; Cryopreservation/methods ; Neoplasms/complications ; Neoplasms/therapy ; Fertility ; Reproduction
Language	Hungarian
Publishing date	2023-07-16
Publishing country	Hungary
Document type	Review ; English Abstract ; Journal Article
ZDB-ID	123879-6
ISSN	1788-6120 ; 0030-6002
ISSN (online)	1788-6120
ISSN	0030-6002
DOI	10.1556/650.2023.32823
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Article ; Online: Gyermek- és felnőttkorú daganatos férfiak nemzőképességének megőrzése.

Vesztergom, Dóra / Takács, Tamás / Bíró, Krisztina / Polgár, Csaba / Krádi, Anna / Varga, Szilvia / Novák, Zoltán / Kopa, Zsolt

Orvosi hetilap

2023 Volume 164, Issue 51, Page(s) 2016–2023

Title translation	Fertility preservation of adult and prepubertal male cancer patients.
MeSH term(s)	Adult ; Humans ; Male ; Fertility Preservation ; Testis ; Neoplasms/therapy ; Cryopreservation
Language	Hungarian
Publishing date	2023-12-24
Publishing country	Hungary
Document type	Journal Article
ZDB-ID	123879-6
ISSN	1788-6120 ; 0030-6002
ISSN (online)	1788-6120
ISSN	0030-6002
DOI	10.1556/650.2023.32953
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Article ; Online: Nõgyógyászati tumorok képvezérelt, intenzitásmodulált adjuváns sugárkezelésével szerzett kezdeti tapasztalataink.

Király, Réka / Pesznyák, Csilla / Varga, Szilvia / Nguyen, Nhung Anhhong / Major, Tibor / Polgár, Csaba

Magyar onkologia

2018 Volume 63, Issue 2, Page(s) 110–115

Abstract: Our goal was to determine the extent of the CTV-PTV margin. Accuracy of patient setup was checked with daily CBCT. Two radiation oncologists performed the image matching independently. The CTV-PTV margin was calculated with the van Herk formula. The ... ...

Title translation	Initial experience with image-guided and intensity-modulated postoperative radiotherapy of gynecological cancer.
Abstract	Our goal was to determine the extent of the CTV-PTV margin. Accuracy of patient setup was checked with daily CBCT. Two radiation oncologists performed the image matching independently. The CTV-PTV margin was calculated with the van Herk formula. The treatment plans were created with the Varian Eclipse v11 planning system, and the treatments were carried out with a Varian TrueBeam accelerator by using RapidArc technique with two full arcs. Dose constraints on the target volume and organs at risk recommended by international bodies were applied. Conformity number (CN) for PTV, V45 and V50 for organs at risk were used to assess and compare the treatment plans of RapidArc and 3D-KRT (conformal radiotherapy) techniques. The average CTV-PTV margins with or without IGRT were 0.67 cm vs. 1.53 cm, 0.66 cm vs. 1.25 cm and 0.34 cm vs. 0.98 cm in vertical, longitudinal and lateral directions, respectively. In case of daily on-line CBCT verification 0.5 cm margin can be used.
MeSH term(s)	Female ; Genital Diseases, Female/radiotherapy ; Humans ; Neoplasms/radiotherapy ; Postoperative Period ; Radiotherapy Dosage ; Radiotherapy, Conformal ; Radiotherapy, Image-Guided ; Radiotherapy, Intensity-Modulated
Language	Hungarian
Publishing date	2018-08-25
Publishing country	Hungary
Document type	Journal Article
ZDB-ID	414033-3
ISSN	2060-0399 ; 0025-0244
ISSN (online)	2060-0399
ISSN	0025-0244
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Article: Analysis of the full-length VP2 protein of canine parvoviruses circulating in Hungary

Cságola, Attila / Varga, Szilvia / Lőrincz, Márta / Tuboly, Tamás

Archives of virology. 2014 Sept., v. 159, no. 9

2014

Abstract: In recent years, the number of cases of disease caused by canine parvovirus 2 (CPV-2) in vaccinated dogs has increased. The aim of the present study was to identify CPV-2 strains present in Hungary. Forty-two out of 50 faecal specimens examined were ... ...

Abstract	In recent years, the number of cases of disease caused by canine parvovirus 2 (CPV-2) in vaccinated dogs has increased. The aim of the present study was to identify CPV-2 strains present in Hungary. Forty-two out of 50 faecal specimens examined were positive, and 25 VP2 sequences were determined and analysed. Based on the current classification, the Hungarian viruses belong to New CPV-2a type, except two viruses that are recombinants of vaccine viruses and CPV-2a strains. The Tyr324Ile alteration was detected for the first time in Europe, and a “Hungarian-specific” substitution (Ala516Thr) was also identified in this study. The immunologically important parts of the currently spreading canine parvoviruses were examined and found to differ greatly from the vaccine strains that are widely used in Hungary.
Keywords	Feline panleukopenia virus ; dogs ; feces ; recombinant vaccines ; viruses ; Hungary
Language	English
Dates of publication	2014-09
Size	p. 2441-2444.
Publishing place	Springer-Verlag
Document type	Article
ZDB-ID	7491-3
ISSN	1432-8798 ; 0304-8608
ISSN (online)	1432-8798
ISSN	0304-8608
DOI	10.1007/s00705-014-2068-5
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Analysis of the full-length VP2 protein of canine parvoviruses circulating in Hungary.

Cságola, Attila / Varga, Szilvia / Lőrincz, Márta / Tuboly, Tamás

Archives of virology

2014 Volume 159, Issue 9, Page(s) 2441–2444

Abstract	In recent years, the number of cases of disease caused by canine parvovirus 2 (CPV-2) in vaccinated dogs has increased. The aim of the present study was to identify CPV-2 strains present in Hungary. Forty-two out of 50 faecal specimens examined were positive, and 25 VP2 sequences were determined and analysed. Based on the current classification, the Hungarian viruses belong to New CPV-2a type, except two viruses that are recombinants of vaccine viruses and CPV-2a strains. The Tyr324Ile alteration was detected for the first time in Europe, and a "Hungarian-specific" substitution (Ala516Thr) was also identified in this study. The immunologically important parts of the currently spreading canine parvoviruses were examined and found to differ greatly from the vaccine strains that are widely used in Hungary.
MeSH term(s)	Amino Acid Substitution ; Animals ; DNA, Viral/chemistry ; DNA, Viral/genetics ; Dog Diseases/virology ; Dogs ; Feces/virology ; Genotype ; Hungary ; Molecular Sequence Data ; Parvoviridae Infections/veterinary ; Parvoviridae Infections/virology ; Parvovirus, Canine/classification ; Parvovirus, Canine/genetics ; Parvovirus, Canine/isolation & purification ; Sequence Analysis, DNA ; Viral Structural Proteins/genetics ; Viral Vaccines/immunology
Chemical Substances	DNA, Viral ; Viral Structural Proteins ; Viral Vaccines
Language	English
Publishing date	2014-09
Publishing country	Austria
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	7491-3
ISSN	1432-8798 ; 0304-8608
ISSN (online)	1432-8798
ISSN	0304-8608
DOI	10.1007/s00705-014-2068-5
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Article ; Online: Durvalumab versus placebo with chemoradiotherapy for locally advanced cervical cancer (CALLA): a randomised, double-blind, phase 3 trial.

Monk, Bradley J / Toita, Takafumi / Wu, Xiaohua / Vázquez Limón, Juan C / Tarnawski, Rafal / Mandai, Masaki / Shapira-Frommer, Ronnie / Mahantshetty, Umesh / Del Pilar Estevez-Diz, Maria / Zhou, Qi / Limaye, Sewanti / Godinez, Francisco J Ramirez / Oppermann Kussler, Christina / Varga, Szilvia / Valdiviezo, Natalia / Aoki, Daisuke / Leiva, Manuel / Lee, Jung-Yun / Sulay, Raymond /

Kreynina, Yulia / Cheng, Wen-Fang / Rey, Felipe / Rong, Yi / Ke, Guihao / Wildsmith, Sophie / Lloyd, Andrew / Dry, Hannah / Tablante Nunes, Ana / Mayadev, Jyoti

The Lancet. Oncology

2023 Volume 24, Issue 12, Page(s) 1334–1348

Abstract: Background: Concurrent chemoradiotherapy has been the standard of care for locally advanced cervical cancer for over 20 years; however, 30-40% of treated patients have recurrence or progression within 5 years. Immune checkpoint inhibition has improved ... ...

Abstract	Background: Concurrent chemoradiotherapy has been the standard of care for locally advanced cervical cancer for over 20 years; however, 30-40% of treated patients have recurrence or progression within 5 years. Immune checkpoint inhibition has improved outcomes for patients with PD-L1 positive metastatic or recurrent cervical cancer. We assessed the benefit of adding durvalumab, a PD-L1 antibody, with and following chemoradiotherapy for locally advanced cervical cancer. Methods: The CALLA randomised, double-blind, phase 3 trial included 105 hospitals across 15 countries. Patients aged at least 18 years with previously untreated locally advanced cervical cancer (adenocarcinoma, squamous, or adenosquamous; International Federation of Gynaecology and Obstetrics [FIGO] 2009 stage IB2-IIB lymph node positive, stage ≥III any lymph node status) and WHO or Eastern Cooperative Oncology Group performance status of 0 or 1 were randomly assigned (1:1) through an interactive web response system using a permuted block size of 4 to receive durvalumab (1500 mg intravenously once every 4 weeks) or placebo with and following chemoradiotherapy, for up to 24 cycles. Chemoradiotherapy included 45 Gy external beam radiotherapy at 5 fractions per week concurrent with intravenous cisplatin (40 mg/m Findings: Between Feb 15, 2019, and Dec 10, 2020, 770 women were randomly assigned (385 to durvalumab and 385 to placebo; median age 49 years [IQR 41-57]). Median follow-up was 18·5 months (IQR 13·2-21·5) in the durvalumab group and 18·4 months (13·2-23·7) in the placebo group. At data cutoff, median progression-free survival had not been reached (95% CI not reached-not reached) for either group (HR 0·84; 95% CI 0·65-1·08; p=0·17); 12-month progression-free survival was 76·0% (71·3-80·0) with durvalumab and 73·3% (68·4-77·5) with placebo. The most frequently reported grade 3-4 adverse events in both groups were anaemia (76 [20%] of 385 in the durvalumab group vs 56 [15%] of 384 in the placebo group) and decreased white blood cells (39 [10%] vs 49 [13%]). Serious adverse events occurred for 106 (28%) patients who received durvalumab and 89 (23%) patients who received placebo. There were five treatment-related deaths in the durvalumab group (one case each of urinary tract infection, blood loss anaemia, and pulmonary embolism related to chemoradiotherapy only; one case of endocrine disorder related to durvalumab only; and one case of sepsis related to both durvalumab and chemoradiotherapy). There was one treatment-related death in the placebo group (pneumonia related to chemoradiotherapy). Interpretation: Durvalumab concurrent with chemoradiotherapy was well tolerated in participants with locally advanced cervical cancer, however it did not significantly improve progression-free survival in a biomarker unselected, all-comers population. Concurrent durvalumab plus chemoradiotherapy warrants further exploration in patients with high tumoral PD-L1 expression. Rigorous monitoring ensured high chemoradiotherapy compliance with advanced technology and allowed patients to receive optimal care. Funding: AstraZeneca.
MeSH term(s)	Adolescent ; Adult ; Female ; Humans ; Middle Aged ; Anemia ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; B7-H1 Antigen ; Chemoradiotherapy/adverse effects ; Double-Blind Method ; Neoplasm Recurrence, Local ; Uterine Cervical Neoplasms/drug therapy
Chemical Substances	B7-H1 Antigen ; durvalumab (28X28X9OKV)
Language	English
Publishing date	2023-12-01
Publishing country	England
Document type	Randomized Controlled Trial ; Clinical Trial, Phase III ; Journal Article
ZDB-ID	2049730-1
ISSN	1474-5488 ; 1470-2045
ISSN (online)	1474-5488
ISSN	1470-2045
DOI	10.1016/S1470-2045(23)00479-5
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Article: A külföldi tőkeberuházások a világgazdaságban, [Teil 1]

Némedi-Varga, Szilvia

Statisztikai szemle : a Központi Statisztikai Hivatal folyóirata Vol. 76, No. 4/5 , p. 390-406

1998 Volume 76, Issue 4, Page(s) 390–406

Author's details	Némedi-Varga Szilvia
Keywords	Auslandsinvestition ; Welt
Language	Hungarian
Size	graph. Darst
Publishing place	Budapest
Document type	Article
Note	Zsfassung in engl. Sprache
ZDB-ID	301006-5 ; 2798576-3
ISSN	0039-0690
ISSN	0039-0690
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Article: Patológiai komplett remisszió preoperatív, nagy dózisteljesítményû brachyterápiát követően operábilis méhnyakdaganatos betegeknél: egy prospektív, randomizált vizsgálat előzetes eredményei.

Vízkeleti, Júlia / Pete, Imre / Vereczkey, Ildikó / Fröhlich, Georgina / Horváth, Katalin / Varga, Szilvia / Pulay, Tamás / Kásler, Miklós / Polgár, Csaba

Magyar onkologia

2012 Volume 56, Issue 3, Page(s) 171–177

Abstract: The purpose of the study was a preliminary evaluation of the efficacy of preoperative intracavitary high-dose-rate brachytherapy (HDR BT) in sterilization of the specimen of operable cervical cancer patients enrolled into a prospective, randomized study. ...

Title translation	Complete pathologic remission after preoperative high-dose brachytherapy in patients with operable cervical cancer: preliminary results of a prospective randomized study.
Abstract	The purpose of the study was a preliminary evaluation of the efficacy of preoperative intracavitary high-dose-rate brachytherapy (HDR BT) in sterilization of the specimen of operable cervical cancer patients enrolled into a prospective, randomized study. Between 2005 and 2010, 100 operable cervical cancer patients of FIGO stage I/A2 (n=4), I/B1 (n=51), I/B2 (n=19), IIA (n=17), and proximal II/B (n=9) were randomized in two arms: in arm "A" (n=50) allocated treatment was 2x8 Gy preoperative intracavitary HDR BT followed by radical surgery, in arm "B" (n= 50) no preoperative treatment was given before the planned radical Wertheim hysterectomy. The rates of pathologic complete remission (pCR) were compared using the Fisher-exact test. In arm "A" 41 patients (82%), in arm "B" 42 patients (84%) underwent radical hysterectomy. The rate of pCR after preoperative BT was 26.8% (11/41), while in the control group the specimen was free of tumor in 7.1% (3/42; p=0.0204). Preoperative HDR BT for cervical cancer patients significantly increases the rate of pathologically tumor-free specimens. Longer follow-up is needed to evaluate the impact of pCR on local tumor control and survival. Our preliminary results support further enrollment of patients into our randomized clinical trial.
MeSH term(s)	Adult ; Aged ; Brachytherapy/methods ; Disease-Free Survival ; Female ; Humans ; Hysterectomy/methods ; Middle Aged ; Neoadjuvant Therapy/methods ; Neoplasm Staging ; Prospective Studies ; Radiotherapy Dosage ; Remission Induction ; Survival Analysis ; Treatment Outcome ; Uterine Cervical Neoplasms/mortality ; Uterine Cervical Neoplasms/pathology ; Uterine Cervical Neoplasms/radiotherapy ; Uterine Cervical Neoplasms/surgery
Language	Hungarian
Publishing date	2012-09
Publishing country	Hungary
Document type	English Abstract ; Journal Article ; Randomized Controlled Trial
ZDB-ID	414033-3
ISSN	0025-0244
ISSN	0025-0244
DOI	MagyOnkol.2012.56.3.171
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