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Article ; Online: Is water vapor thermal therapy safe and feasible in elderly and frail men? The Italian experience.

Minore, Antonio / Morselli, Simone / Franzoso, Francesco / Maruzzi, Daniele / Varvello, Francesco / Toso, Stefano / Ferrari, Giovanni / Siena, Giampaolo / Conti, Enrico / Papalia, Rocco / Uricchio, Francesco / Balsamo, Raffaele / Scarpa, Roberto Mario / Cindolo, Luca

World journal of urology

2024 Volume 42, Issue 1, Page(s) 60

Abstract: Purpose: In recent years, water vapor thermal therapy (WVTT) has spread as minimally invasive technique in lower urinary tract symptoms due to benign prostatic hyperplasia treatment. Even if its safety and feasibility have been largely proved in young ... ...

Abstract	Purpose: In recent years, water vapor thermal therapy (WVTT) has spread as minimally invasive technique in lower urinary tract symptoms due to benign prostatic hyperplasia treatment. Even if its safety and feasibility have been largely proved in young men, nobody has proved the same feasibility and safety in the elderly (men older than 75 years old). Our aim is to compare WVTT safety outcomes in men older than 75 with younger men. Methods: We prospectively collected data on men who underwent water vapor thermal therapy from 2019. We compared data on operative time, number of injections, intra-operative and post-operative complications, reinterventions rate. Results: We enrolled 426 patients; among these, 60 were older than 75 years old, 366 were younger. Our cohorts of patients had similar results in terms of intra-operative and post-operative complications. Operative time accounts about 11 min for both groups (p = 0.535), total number of injections was seven for young men and eight for elderly (p = 0.314). We found no intra-operative complications in elderly men group and only one in the younger group (p = 0.678), while five younger men underwent clot retention, and two elderly men experienced this complication (p = 0.239). Only one transfusion occurred in the elderly group. No differences between groups occurred in terms of length of stay, post-operative urinary retention and reintervention rate, while catheterization time was longer in the elderly men. Conclusion: WVTT is a safe procedure in elderly patients with comparable intra-operative and post-operative complication rate in comparison with younger patients.
MeSH term(s)	Male ; Aged ; Humans ; Steam ; Frail Elderly ; Prostatic Hyperplasia/complications ; Hyperthermia, Induced/methods ; Italy ; Lower Urinary Tract Symptoms/etiology ; Treatment Outcome
Chemical Substances	Steam
Language	English
Publishing date	2024-01-27
Publishing country	Germany
Document type	Journal Article
ZDB-ID	380333-8
ISSN	1433-8726 ; 0724-4983
ISSN (online)	1433-8726
ISSN	0724-4983
DOI	10.1007/s00345-023-04762-9
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Article ; Online: One-year outcomes after water vapor thermal therapy for symptomatic benign prostatic hyperplasia in an unselected Italian multicenter cohort.

Cindolo, Luca / Morselli, Simone / Campobasso, Davide / Conti, Enrico / Sebastiani, Giancarlo / Franzoso, Francesco / Galluccio, Giuseppe / Maruzzi, Daniele / Visalli, Francesco / Varvello, Francesco / Lucci Chiarissi, Marco / Viola, Lorenzo / Sessa, Francesco / Toso, Stefano / Micali, Salvatore / Ferrari, Giovanni / Siena, Giampaolo

Minerva urology and nephrology

2023 Volume 75, Issue 2, Page(s) 203–209

Abstract: Background: Water vapor therapy (Rezum: Methods: Patients with BPO and moderate to severe LUTS who underwent Rezum: Results: Overall, 352 patients were eligible for the analysis. Procedures were routinely done on an outpatient basis. Mean ... ...

Abstract	Background: Water vapor therapy (Rezum Methods: Patients with BPO and moderate to severe LUTS who underwent Rezum Results: Overall, 352 patients were eligible for the analysis. Procedures were routinely done on an outpatient basis. Mean operative was 12 minutes. The catheter was left in place for a median of 7 days. After treatment, Q<inf>max</inf>, IPSS and IPSS-QoL, OAB-q SF, ICIQ-UI SF and IIEF-5 from baseline to last control follow-up (median 16, IQR 13-20 months) were improved (P<0.05). The postoperative anterograde ejaculation rate was recorded in 74.1% vs. preoperative 43.8% (P<0.001). Early (≤30 days) postoperative complications occurred in 176 patients (50%), all Clavien-Dindo Grade ≤2. One patient experienced clot retention and hematuria requiring hospitalization and blood transfusion. No late AEs were recorded. Surgical retreatment rate was 2.5% (9/352), all cases occurred within the first year. Median PGI-I was 2 (1-2). Conclusions: We confirmed the safety and efficacy of water vapor therapy for the treatment of symptomatic benign prostatic obstruction (BPO) on a large cohort of patients. Anterograde ejaculation was preserved in the majority of patients, with good subjective improvement. Further studies may rule out possible role of Rezum
MeSH term(s)	Male ; Humans ; Prostatic Hyperplasia/complications ; Prostatic Hyperplasia/surgery ; Steam ; Quality of Life ; Treatment Outcome ; Prostate/surgery
Chemical Substances	Steam
Language	English
Publishing date	2023-01-19
Publishing country	Italy
Document type	Multicenter Study ; Journal Article
ZDB-ID	3062840-4
ISSN	2724-6442
ISSN (online)	2724-6442
DOI	10.23736/S2724-6051.22.05080-7
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Article ; Online: Do Patients Treated with Water Vapor Therapy and Meeting Randomized Clinical Trial Criteria Have Better Urinary and Sexual Outcomes Than an Unselected Cohort?

Cindolo, Luca / Campobasso, Davide / Conti, Enrico / Uricchio, Francesco / Franzoso, Francesco / Maruzzi, Daniele / Viola, Lorenzo / Varvello, Francesco / Balsamo, Raffaele / Ferrari, Giovanni / Morselli, Simone / Siena, Giampaolo

Journal of endourology

2022 Volume 37, Issue 3, Page(s) 323–329

Abstract: Introduction: ...

Abstract	Introduction:
MeSH term(s)	Male ; Humans ; Prostatic Hyperplasia/drug therapy ; Prostatic Hyperplasia/surgery ; Prostatic Hyperplasia/complications ; Steam ; Treatment Outcome ; Lower Urinary Tract Symptoms/etiology ; Transurethral Resection of Prostate/methods
Chemical Substances	Steam
Language	English
Publishing date	2022-12-20
Publishing country	United States
Document type	Randomized Controlled Trial ; Multicenter Study ; Journal Article
ZDB-ID	356931-7
ISSN	1557-900X ; 0892-7790
ISSN (online)	1557-900X
ISSN	0892-7790
DOI	10.1089/end.2022.0637
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Zs.A 2628: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Composite urinary and sexual outcomes after Rezum: an analysis of predictive factors from an Italian multi-centric study.

Campobasso, Davide / Siena, Giampaolo / Chiodini, Paolo / Conti, Enrico / Franzoso, Francesco / Maruzzi, Daniele / Martinelli, Evangelista / Varvello, Francesco / De Nunzio, Cosimo / Autorino, Riccardo / Somani, Bhaskar Kumar / Ferrari, Giovanni / Cindolo, Luca

Prostate cancer and prostatic diseases

2022 Volume 26, Issue 2, Page(s) 410–414

Abstract: Background: The Rezum system is one of the latest minimally invasive surgical treatments for benign prostatic hyperplasia.: Methods: We retrospectively reviewed all patients who underwent the Rezum treatment in seven different Italian institutions. A ...

Abstract	Background: The Rezum system is one of the latest minimally invasive surgical treatments for benign prostatic hyperplasia. Methods: We retrospectively reviewed all patients who underwent the Rezum treatment in seven different Italian institutions. A successful urinary outcome was defined as: ≥50% improvement in the IPSS <7, improvement in peak flow ≥50% and/or more than 15 ml/s, ≥1-point improvement in the QoL questionnaire and in the absence of perioperative major complications (AUR, transfusion) or postoperative incontinence. A successful sexual outcome was defined as postoperative (latest follow up consultation) antegrade ejaculation or no variation in ejaculatory function and an increase, or stability or max 1 class reduction, in IIEF-5. Results: 262 patients were enrolled with a follow-up period of 11 months (IQR 5-15). No early or late serious adverse events (Clavien III-IV) occurred. Early complications occurred in 39.3% of cases, with 4 cases of clot retention and one case of blood transfusion. Urge incontinence was reported by 6 patients (2.2%). A treatment failure requiring re-intervention occurred in 4 cases (1.5%). The preoperative antegrade ejaculation rate was 56.5%, and after the procedure it increased to 78.2%. The increase of ≥1-point in the QoL was achieved in 92.7% of the cases. Optimal urinary and sexual outcomes were achieved in 52.9% and 87.8%, respectively. Conclusions: In our series, water vapor intraprostatic injections seem to be an effective and safe procedure.
MeSH term(s)	Male ; Humans ; Treatment Outcome ; Retrospective Studies ; Quality of Life ; Prostatic Neoplasms/complications ; Prostatic Hyperplasia/complications ; Lower Urinary Tract Symptoms/etiology
Language	English
Publishing date	2022-08-30
Publishing country	England
Document type	Journal Article
ZDB-ID	1419277-9
ISSN	1476-5608 ; 1365-7852
ISSN (online)	1476-5608
ISSN	1365-7852
DOI	10.1038/s41391-022-00587-6
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Zs.A 5277: Show issues

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Article ; Online: Efficacy and safety profile of GreenLight laser photoselective vaporization of the prostate in ≥ 75 years old patients: results from the Italian GreenLight Laser Study Group.

Campobasso, Davide / Morselli, Simone / Greco, Francesco / De Nunzio, Cosimo / Destefanis, Paolo / Fasolis, Giuseppe / Varvello, Francesco / Voce, Salvatore / Reale, Giulio / Cai, Tommaso / Oriti, Rino / Tuccio, Agostino / Ruggera, Lorenzo / Laganà, Antonino / Dadone, Claudio / Gontero, Paolo / De Rienzo, Gaetano / Pucci, Luigi / Carrino, Maurizio /

Montefiore, Franco / Rabito, Salvatore / Miano, Roberto / Schips, Luigi / Frattini, Antonio / Micali, Salvatore / Ferrari, Giovanni / Cindolo, Luca

Aging clinical and experimental research

2023 Volume 35, Issue 4, Page(s) 877–885

Abstract: Background: Benign Prostatic Obstruction (BPO) is the most common non-malignant urological condition among men and its incidence rise with age. Among prostate treatments, GreenLight laser seems to reduce bleeding and would be safer in the aging ... ...

Abstract	Background: Benign Prostatic Obstruction (BPO) is the most common non-malignant urological condition among men and its incidence rise with age. Among prostate treatments, GreenLight laser seems to reduce bleeding and would be safer in the aging population. Aims: We aimed to compare the functional outcomes and safety profile of < 75 years old (Group A) and ≥ 75 years old (Group B) patients. Methods: In a multicenter setting, we retrospectively analyzed all the patients treated with GreenLight Laser vaporization of the prostate (PVP). Results: 1077 patients were eligible for this study. 757 belonged to Group A (median age 66 years) and 320 to Group B (median age 78 years). No differences were present between the two groups in terms of prostate volume, operative time, hospital stay, PSA decrease over time after surgery, complications and re-intervention rate with a median follow-up period of 18 months (IQR 12-26). Nevertheless, focusing on complications, GreenLight laser PVP demonstrated an excellent safety profile in terms of hospital stay, re-intervention and complications, with an overall 29.6% complication rate in older patients and only two cases of Clavien III. Functional outcomes were similar at 12 month and became in favor of Group A over time. These data are satisfactory with a Qmax improvement of 111.7% and an IPSS reduction of 69.5% in older patients. Discussion and conclusions: GreenLight laser photoselective vaporization of the prostate is a safe and efficient procedure for all patients, despite their age, with comparable outcomes and an equal safety profile.
MeSH term(s)	Male ; Humans ; Aged ; Prostate/surgery ; Prostate/pathology ; Prostatic Hyperplasia/surgery ; Prostatic Hyperplasia/complications ; Prostatic Hyperplasia/pathology ; Retrospective Studies ; Volatilization ; Lasers ; Laser Therapy/adverse effects ; Laser Therapy/methods ; Treatment Outcome
Language	English
Publishing date	2023-02-10
Publishing country	Germany
Document type	Multicenter Study ; Journal Article
ZDB-ID	2104785-6
ISSN	1720-8319 ; 1594-0667
ISSN (online)	1720-8319
ISSN	1594-0667
DOI	10.1007/s40520-023-02351-9
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Zs.A 3343: Show issues

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Article ; Online: The safety and feasibility of the simultaneous use of 180-W GreenLight laser for prostate vaporization during concomitant surgery.

Castellucci, Roberto / Marchioni, Michele / Fasolis, Giuseppe / Varvello, Francesco / Ditonno, Pasquale / Di Rienzo, Gaetano / Greco, Francesco / Altieri, Vincenzo Maria / Frattini, Antonio / Ferrari, Giovanni / Schips, Luigi / Cindolo, Luca

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica

2020 Volume 92, Issue 4

Abstract: Objectives: To explore the safety and feasibility of photo-selective vaporization of the prostate (PVP) with GreenLight XPS 180 Watt laser (GL-180- W XPS) combined with other surgical procedures.: Material and methods: Data on patients in whom GL-180- ...

Abstract	Objectives: To explore the safety and feasibility of photo-selective vaporization of the prostate (PVP) with GreenLight XPS 180 Watt laser (GL-180- W XPS) combined with other surgical procedures. Material and methods: Data on patients in whom GL-180-W XPS was performed to relieve lower urinary tract symptoms/ benign prostatic hyperplasia (LUTS/BPH) symptoms were extracted from a multi-institutional database (2011-2016). Patients were stratified into two groups. In the first all patients who had GL-180-W XPS with a concomitant procedure during the same surgical session were included as cases while those who underwent GL-180-W XPS PVP only were included as control. Results: A total of 487 patients were included. Fifty-eight (11.9%) patients underwent concomitant procedures. Multivariable linear regression models failed to find an association between concomitant procedures and longer laser time (p = 0.4). Similarly, multivariable linear regression models failed to find an association between concomitant procedures and laser time even when the analyses were repeated and stratified into endoscopic (p = 0.6) and open/laparoscopic (p = 0.4) procedures. Multivariable logistic regression models failed to demonstrate any association between concomitant procedures and early complications (OR:1.39, CI: 0.379-2.44, p = 0.2), late complications (OR:1.84, CI:0.78-3.98; p = 0.1) and acute urinary retention (OR:1.84, CI:0.78-3.98; p = 0.1). When the analyses were repeated and the concomitant procedures stratified into endoscopic and open/laparoscopic ones, they yielded virtually the same results. Conclusions: GL-180-W XPS PVP could be safely performed in concomitant endoscopic or open/laparoscopic surgery. These results should be taken into consideration in the counseling of the patient who might choose to undergo simultaneous procedures.
MeSH term(s)	Aged ; Feasibility Studies ; Humans ; Laser Therapy/adverse effects ; Laser Therapy/methods ; Lower Urinary Tract Symptoms/etiology ; Lower Urinary Tract Symptoms/surgery ; Male ; Middle Aged ; Prostatic Hyperplasia/complications ; Prostatic Hyperplasia/surgery ; Retrospective Studies ; Urologic Surgical Procedures, Male
Language	English
Publishing date	2020-12-17
Publishing country	Italy
Document type	Journal Article
ZDB-ID	1153526-x
ISSN	2282-4197 ; 1120-8538 ; 1124-3562
ISSN (online)	2282-4197
ISSN	1120-8538 ; 1124-3562
DOI	10.4081/aiua.2020.4.297
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Article: Impiego dell'esame estemporaneo al congelatore per la valutazione dei margini chirurgici in corso di prostatectomia radicale

Varvello, Francesco / Conti, Enrico / Camilli, Marco / Lacquaniti, Sergio / Fasolis, Giuseppe

Urologia

2013 Volume 80 Suppl 22, Page(s) 39–43

Abstract: Introduction: At present there is no consensus on the use of frozen sections (FS) during radical prostatectomy. Several groups have proposed the benefit of FS although the studies differ widely in sampling methods and sites where FS were taken. This ... ...

Title translation	Use of frozen sections to assess surgical margins during radical prostatectomy.
Abstract	Introduction: At present there is no consensus on the use of frozen sections (FS) during radical prostatectomy. Several groups have proposed the benefit of FS although the studies differ widely in sampling methods and sites where FS were taken. This study aims to evaluate the usefulness and reliability of standard assessment of FS in multiple sites during radical prostatectomy. Methods: During open radical prostatectomy in all patients we sampled tissue from the urethral stump, the neurovascular bundles, the Denonvillier fascia and the bladder neck after removing the prostate. Where FS showed positive margins, further periprostatic tissue was resected from the prostatic bed until negative margins were achieved. The results of FS were compared with margin status of final pathology. Results: From 1998 to 2004 we performed FS during 250 consecutive open radical prostatectomies (104 nerve sparing procedures). 66 patients had positive FS (26.4%) and 53 patients had positive surgical margins at final pathology (21.2%). All patients with positive FS had negative margins when further tissue was resected in the prostatic bed. During nerve sparing procedures positive FS were found in 14 patients. In these cases the procedure was converted into standard prostatectomy by resecting the neurovascular bundles. Sensibility and specificity were both 90%. Positive and negative predictive values were respectively 72% and 97%. Conclusions: Standard assessment of FS in multiple sites during radical prostatectomy achieved sensibility and specificity as high as 90%. Although the resection of urethral stump and tissue close to the neurovascular bundles could compromise functional results, standard assessment of FS in multiple sites could help the surgeon to reduce the positive surgical margins, to monitor the oncological safety of a nerve sparing procedure and to improve the pathological staging.
MeSH term(s)	Frozen Sections ; Humans ; Intraoperative Period ; Male ; Prostatectomy/methods ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms/surgery
Language	Italian
Publishing date	2013-04-24
Publishing country	Italy
Document type	English Abstract ; Journal Article
ZDB-ID	204043-8
ISSN	1724-6075 ; 0391-5603 ; 0376-0057
ISSN (online)	1724-6075
ISSN	0391-5603 ; 0376-0057
DOI	10.5301/RU.2013.10594
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Article ; Online: Which patient may benefit the most from penile prosthesis implantation?

Andrology

2022 Volume 10, Issue 8, Page(s) 1567–1574

Abstract: Background: Penile prosthesis implantation has been associated with overall good functional outcomes. Of relevance, some patients reported higher level of satisfaction and quality of life.: Aim: We investigated the profile of the patients who may ... ...

Abstract	Background: Penile prosthesis implantation has been associated with overall good functional outcomes. Of relevance, some patients reported higher level of satisfaction and quality of life. Aim: We investigated the profile of the patients who may benefit the most from penile prosthesis implantation. Materials and methods: Data from a national multi-institutional registry of penile prostheses including patients treated from 2014 to 2017 in Italy (Italian Nationwide Systematic Inventarization of Surgical Treatment for Erectile Dysfunction) were analyzed. All data have been prospectively recorded by 45 surgeons on a dedicated website (www.registro.andrologiaitaliana.it) and revised by a single data manager. Patients' baseline characteristics were recorded. In order to simultaneously evaluate perceived penile prosthesis function and quality of life, all patients were re-assessed at 1-year follow-up using the validated questionnaire Quality of Life and Sexuality with Penile Prosthesis. High quality of life after surgery was defined as a score higher than the 75th percentile in each of the subdomains of the Quality of Life and Sexuality with Penile Prosthesis questionnaire. Logistic regression analysis tested the association between clinical characteristics and high quality of life after penile prosthesis implantation. Results: Follow-up data were available for 285 patients (median age 60 years; interquartile range: 56-67) who underwent penile prosthesis implantation. Erectile dysfunction etiology was organic in 40% (114), pelvic surgery/radiotherapy in 39% (111), and Peyronie's disease in 21% (60) of the cases. Patients showed good overall Quality of Life and Sexuality with Penile Prosthesis scores at 1-year follow-up for functional (22/25), personal (13/15), relational (17/20), and social (13/15) domains. Overall, 27.0% (77) of patients achieved scores consistent with the high quality of life definition. These patients did not differ in terms of median age (60 vs. 62), type of prosthesis (inflatable penile prostheses: 95% in both of the cases), and post-operative complications (10% vs. 14%) than those with lower quality of life score (all p > 0.1). At logistic regression analysis, erectile dysfunction etiology was the only factor independently associated with high quality of life at 1 year after surgery (p = 0.02). Patients treated for Peyronie's disease (odds ratio: 2.62; p = 0.01; 95% confidence interval: 1.20-5.74) were more likely to report better outcomes after accounting for age, post-operative complications, and surgical volume. Conclusion: Penile prosthesis implantation is associated with an overall good quality of life. The subset of patients affected by erectile dysfunction secondary to Peyronie's disease seemed to benefit the most from penile prosthesis implantation in terms of functional outcomes, relationship with their partners and the outside world, and perceived self-image. The systematic use of validated questionnaires specifically addressed at evaluating quality of life and satisfaction after penile prosthesis implantation should be further implemented in future studies to better define the predictors of optimal satisfaction after penile prosthesis implantation.
MeSH term(s)	Erectile Dysfunction/complications ; Erectile Dysfunction/surgery ; Humans ; Male ; Middle Aged ; Patient Satisfaction ; Penile Implantation/adverse effects ; Penile Implantation/methods ; Penile Induration/surgery ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Quality of Life
Language	English
Publishing date	2022-09-26
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2696108-8
ISSN	2047-2927 ; 2047-2919
ISSN (online)	2047-2927
ISSN	2047-2919
DOI	10.1111/andr.13294
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Article ; Online: Risk of unfavorable outcomes after penile prosthesis implantation - results from a national registry (INSIST-ED).

Preto, Mirko / Falcone, Marco / Plamadeala, Natalia / Schifano, Nicolò / Bettocchi, Carlo / Colombo, Fulvio / Fiordelise, Stefano / Vitarelli, Antonio / Silvani, Mauro / Mondaini, Nicola / Paradiso, Matteo / Ceruti, Carlo / Varvello, Francesco / Palumbo, Fabrizio / Avolio, Antonio / Antonini, Gabriele / Corvasce, Antonio / Pozza, Diego / Franco, Giorgio /

International journal of impotence research

2023

Abstract: Like all surgeries, penile prosthesis implantation (PPI) has the potential for both postoperative complications and suboptimal patient satisfaction. In order to assess risk factors for poor satisfaction, we reviewed patients who had been prospectively ... ...

Abstract	Like all surgeries, penile prosthesis implantation (PPI) has the potential for both postoperative complications and suboptimal patient satisfaction. In order to assess risk factors for poor satisfaction, we reviewed patients who had been prospectively recruited in a national multi-institutional registry of penile prostheses procedures (INSIST-ED) from 2014 to 20121. Patient baseline characteristics and postoperative complications were recorded. The primary endpoint of this study was unfavorable outcomes after inflatable PPI, defined as significant postoperative complications (Clavien-Dindo ≥2) and/or Sexuality with Quality of Life and Sexuality with Penile Prosthesis (QoLSPP) scores below the 10th percentile. A total of 256 patients were included in the study. The median age was 60 years (IQR 56-67). The most common cause of erectile dysfunction (ED) was organic (42.2%), followed by pelvic surgery/radiotherapy (39.8%) and Peyronie's disease (18.0%). Postoperative complications were recorded in 9.6%. High-grade complications (Clavien ≥2) occurred in 4.7%. At 1-year follow-up, the median QoLSPP total score was 71 (IQR 65-76). In all, 14.8% of patients were classified as having experienced unfavorable outcomes because of significant postoperative complications and/or QoLSPP scores below the 10th percentile. Logistic regression analysis demonstrated patient age to be non-linearly associated with the risk of experiencing unfavorable outcomes. A U-shaped correlation showed a lower risk for younger and older patients and a higher risk for middle-aged men. ED etiology and surgical volume were not associated with PPI outcomes. Physicians should, therefore, be aware that middle-aged men may be at higher risk of being unsatisfied following PPI compared to both younger and older patients.
Language	English
Publishing date	2023-10-31
Publishing country	England
Document type	Journal Article
ZDB-ID	1034295-3
ISSN	1476-5489 ; 0955-9930
ISSN (online)	1476-5489
ISSN	0955-9930
DOI	10.1038/s41443-023-00784-4
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Article: Therapeutic ureteral occlusion with Ifabond cyanoacrylate glue: an interesting solution.

Oderda, Marco / Lacquaniti, Sergio / Fraire, Flavio / Antolini, Jacopo / Camilli, Marco / Mandras, Roberto / Puccetti, Luca / Varvello, Francesco / Fasolis, Giuseppe

Urologia

2017 Volume 84, Issue 3, Page(s) 203–205

Abstract: Objective: The aim of this study was to present a novel approach for complete and permanent ureteral occlusion using a percutaneous injection of Ifabond cyanoacrylate glue.: Methods: We describe in detail all the steps of our surgery, performed on a ... ...

Abstract	Objective: The aim of this study was to present a novel approach for complete and permanent ureteral occlusion using a percutaneous injection of Ifabond cyanoacrylate glue. Methods: We describe in detail all the steps of our surgery, performed on a 79-year-old patient with urinary leakage from ureteral stump following radical cystectomy. N-hexyl-cyanoacrylate glue (Ifabond) was used to occlude the distal ureter and solve the leakage. Results: Our approach was successful, sparing our already frail patient further surgical procedures. Six months pyelography confirmed the complete ureteral blockage with absence of extravasation. Conclusions: In complicated scenarios with urinary leakages and frail patients, synthetic glues such as Ifabond might represent an interesting therapeutic option to solve the fistulas, leading to durable success with a minimally invasive approach.
Language	English
Publishing date	2017-08-01
Publishing country	Italy
Document type	Journal Article
ZDB-ID	204043-8
ISSN	1724-6075 ; 0391-5603 ; 0376-0057
ISSN (online)	1724-6075
ISSN	0391-5603 ; 0376-0057
DOI	10.5301/uro.5000217
Database	MEDical Literature Analysis and Retrieval System OnLINE

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