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  1. Article ; Online: Results of a simple treatment protocol for aseptic femoral shaft nonunion in 330 patients.

    Devendra, Agraharam / Patra, Sudipta Kumar / Velmurugesan, P / Zackariya, Mohd / Ramesh, P / Arun Kamal, Chandramohan / Dheenadhayalan, Jayaramaraju / Rajasekaran, Shanmuganathan

    Injury

    2024  Volume 55, Issue 3, Page(s) 111412

    Abstract: Introduction: Our primary aim of the study was to assess the results of a treatment protocol for aseptic femoral shaft nonunion treated by three techniques - Exchange Nailing (EN), Plate Augmentation (PA), and Exchange Nailing combined with Plate ... ...

    Abstract Introduction: Our primary aim of the study was to assess the results of a treatment protocol for aseptic femoral shaft nonunion treated by three techniques - Exchange Nailing (EN), Plate Augmentation (PA), and Exchange Nailing combined with Plate augmentation (NP). The secondary objective was to assess the radiological outcome, duration of surgery (DOS) and need for blood transfusion (BT) in all the three groups.
    Materials and methods: We analyzed 330 patients treated for AFNU between Jan 2007 and Dec 2019. Using a simple treatment algorithm, EN, PA and NP were performed in 24,183 and 123 patients respectively. Patients in all the three groups were assessed for radiological-union (union rate and time to union), DOS and BT.
    Results: Of these 330 patients, 327 (99 %) patients achieved radiological union at a mean duration of 6.07 months. Union rate is highest with NP followed by PA and EN. The union rate in patients with NP, PA and EN were 100 %, 99.5 % and 91.7 % respectively (p < 0.01). Time to union was lowest for NP followed by PA and EN (p < 0.001).The mean time to union for NP, PA and EN were 3.76, 7.2and 9.21 months respectively (p < 0.001). The mean DOS in minutes for NP, EN and PA was 107, 94 and 82 respectively (p < 0.01). The mean need for BT in the form of packed red blood cells for NP, PA and EN were 1.95, 1.87 and 1.38 units respectively (p < 0.01).
    Conclusion: Following a simple algorithm to decide treatment protocol on a case-to case basis helps to achieve good results in an optimal time period. When compared with EN and PA, NP is associated with 100 % union rate with least time to union making NP a reasonably effective procedure with a very high success rate.
    Level of evidence: IV.
    MeSH term(s) Humans ; Fracture Fixation, Intramedullary/methods ; Treatment Outcome ; Femoral Fractures/diagnostic imaging ; Femoral Fractures/surgery ; Femoral Fractures/etiology ; Fractures, Ununited/surgery ; Fractures, Ununited/etiology ; Bone Nails/adverse effects ; Bone Plates ; Clinical Protocols ; Retrospective Studies
    Language English
    Publishing date 2024-02-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2024.111412
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Surgical management of peripheral artery pseudoaneurysm following orthopedic trauma: a report of 14 cases.

    Devendra, A / Nishith, P Gupta / Velmurugesan, P / Venkatramani, Hari / Dheenadhayalan, J / Rajasekaran, S

    European journal of trauma and emergency surgery : official publication of the European Trauma Society

    2020  Volume 48, Issue 1, Page(s) 637–645

    Abstract: Purpose: Purpose of this study was to report the etiology, diagnosis, surgical management, and outcome of pseudoaneurysm associated with orthopedic trauma.: Methods: A retrospective review was conducted of all patients presenting to a Level 1 trauma ... ...

    Abstract Purpose: Purpose of this study was to report the etiology, diagnosis, surgical management, and outcome of pseudoaneurysm associated with orthopedic trauma.
    Methods: A retrospective review was conducted of all patients presenting to a Level 1 trauma center between 2013 and 2019. Clinical records were reviewed for the mechanism of primary injury, associated fracture pattern, time of presentation, site of involvement, etiology of the pseudoaneurysm, diagnosis, management, and complications. We identified 14 patients with pseudoaneurysm of peripheral arteries following orthopedic trauma.
    Results: The mean interval between primary injury and the manifestation of clinical symptoms was 88.5 days (range, 16-304 days). There were 3 upper limb injuries and 11 lower limb injuries. The presenting symptoms were pain associated with excessive extremity swelling in most of the patients. A significant drop in hemoglobin (mean fall- 2.9 g/dL) was noted in nine patients. Most common artery involved was the superficial branch of femoral artery and posterior tibial artery followed by the brachial artery. Fractured bone spike was the cause of injury in eight patients and iatrogenic injury in six patients. Diagnosis was confirmed by CT angiography with duplex scan in eight patients, duplex scan alone in one patient, MRI along with duplex scan in one patient. The remaining four patients were diagnosed intraoperatively. Excision of the pseudoaneurysm and ligation of the involved minor arteries was done in eight patients. Surgical repair of the major artery with critical vascular injury was done in six patients. One patient underwent secondary amputation following the anastomotic blowout.
    Conclusion: Early diagnosis of pseudoaneurysm requires knowledge and a high index of suspicion. Surgical reconstruction of major arteries should always be done and ligation of major vessels can lead to catastrophes. Excision of pseudoaneurysm can be done when minor arteries are involved with the presence of good collateral circulation.
    Level of study: Level IV Study.
    MeSH term(s) Aneurysm, False/diagnostic imaging ; Aneurysm, False/etiology ; Aneurysm, False/surgery ; Femoral Artery ; Humans ; Lower Extremity ; Retrospective Studies ; Treatment Outcome ; Vascular System Injuries/diagnostic imaging ; Vascular System Injuries/surgery
    Language English
    Publishing date 2020-11-23
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 2275480-5
    ISSN 1863-9941 ; 1863-9933
    ISSN (online) 1863-9941
    ISSN 1863-9933
    DOI 10.1007/s00068-020-01546-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Reconstruction of Massive Segmental Distal Femoral Metaphyseal Bone Defects After Open Injury: A Study of 20 Patients Managed with Intercalary Gamma-Irradiated Structural Allografts and Autologous Cancellous Grafts.

    Dheenadhayalan, J / Devendra, A / Velmurugesan, P / Shanmukha Babu, T / Ramesh, P / Zackariya, Mohd / Sabapathy, S Raja / Rajasekaran, S

    The Journal of bone and joint surgery. American volume

    2021  Volume 104, Issue 2, Page(s) 172–180

    Abstract: Background: Our aim was to examine the outcome of gamma-irradiated intercalary structural allografts combined with autologous cancellous grafts in treating large metaphyseal bone defects of the distal femur following open injuries.: Methods: We ... ...

    Abstract Background: Our aim was to examine the outcome of gamma-irradiated intercalary structural allografts combined with autologous cancellous grafts in treating large metaphyseal bone defects of the distal femur following open injuries.
    Methods: We prospectively included 20 consecutive patients with large metaphyseal bone defects of >4 cm located in the region of the distal femur following open injuries treated between 2010 and 2018, with a mean follow-up of 2 years (range, 2 to 10 years). Of these patients,18 were men and 2 were women. The mean age was 39 years (range, 22 to 72 years). The mean length of the bone defects was 10.1 cm (range, 5.5 to 14.5 cm), and all were in the metaphysis of the distal femur. The surgical technique included initial early debridement and external fixation followed by reconstruction of the bone defect using structural allograft combined with autologous cancellous bone graft harvested from the iliac crest and locking plate fixation. Definitive fixation was performed at an average period of 22.5 days (range, 3 to 84 days) after injury. Osseous union, rate of infection, complications, need for secondary procedures, and functional outcome using the Lower Extremity Functional Scale (LEFS) at the final follow-up were assessed.
    Results: After excluding 1 patient who was lost to follow-up, 19 patients with complete follow-up were available for analysis. Of those, 13 patients (68%) achieved complete union at both ends of the allograft with host bone without any further intervention. Three patients (16%) developed aseptic nonunion of the proximal end of the allograft requiring 1 additional procedure each to achieve union. Four patients (21%) developed a deep surgical site infection. Of those, 1 elderly patient required above-the-knee amputation following uncontrolled diabetes and infection. A second patient required 2 additional procedures, and a third patient needed 4 additional procedures to achieve union. The fourth patient developed infection after achieving union, and the infection subsided after debridement and implant removal. The mean LEFS score for all 19 patients was 55 (range, 41 to 75).
    Conclusions: Use of allograft was a reasonable single-stage alternative solution for massive distal femoral bone defects, which united without additional surgery in two-thirds of the patients and without limb-length discrepancy.
    Level of evidence: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
    MeSH term(s) Adult ; Aged ; Allografts ; Autografts ; Bone Transplantation/methods ; Disability Evaluation ; Female ; Femur/injuries ; Femur/surgery ; Humans ; Leg Injuries/surgery ; Male ; Middle Aged ; Postoperative Complications/surgery ; Plastic Surgery Procedures/methods
    Language English
    Publishing date 2021-09-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 220625-0
    ISSN 1535-1386 ; 0021-9355
    ISSN (online) 1535-1386
    ISSN 0021-9355
    DOI 10.2106/JBJS.21.00065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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