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Article: The aid of microsurgical instruments in nasolabial cyst enucleation. A report of two cases with critical review of the therapeutic approach.

Tilaveridis, Ioannis / Venetis, Gregory / Tatsis, Dimitris / Kalaitsidou, Ioanna / Zouloumis, Lambros

2023 Volume 2023, Issue 1, Page(s) rjad011

Abstract: Nasolabial cysts are rare non-odontogenic cysts related to epithelial remnants of the nasolacrimal duct, slowly enlarging and provoking extraoral swelling in the nasolabial fold with obstruction of the naris. Two patients of large unilateral nasolabial ... ...

Abstract	Nasolabial cysts are rare non-odontogenic cysts related to epithelial remnants of the nasolacrimal duct, slowly enlarging and provoking extraoral swelling in the nasolabial fold with obstruction of the naris. Two patients of large unilateral nasolabial cysts are reported, appearing as cosmetically unappealing distention of the nasolabial fold. Diagnosis is based on clinical characteristics. Computed tomography imaging reveals the dimensions of the cyst, the correlation to the nasal cavity and might depict a depression on the labial surface of the maxilla. Intraoral surgical enucleation of the cystic wall or nasal marsupialization is the main treatment modalities. However, both procedures are related to a small percentage of recurrence. Microsurgical instruments were used to dissect the cystic wall from the nasal mucosa. The aim of this paper is to stress the implementation of microsurgical instruments to separate the cystic wall of the nasolabial cyst from the thin and friable nasal mucosa to avoid recurrence.
Language	English
Publishing date	2023-01-25
Publishing country	England
Document type	Case Reports
ZDB-ID	2580919-2
ISSN	2042-8812
ISSN	2042-8812
DOI	10.1093/jscr/rjad011
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Article: Immunohistochemical Expression of Epithelial Cell Adhesion Molecule (EpCAM) in Salivary Gland Cancer: Correlation with the Biological Behavior.

Kalaitsidou, Ioanna / Pasteli, Nikoleta / Venetis, Gregory / Poulopoulos, Athanasios / Antoniades, Konstantinos

Diagnostics (Basel, Switzerland)

2023 Volume 13, Issue 16

Abstract: Salivary gland neoplasms comprise a diverse group of tumors with different biological behaviors and clinical outcomes. Understanding the underlying molecular alterations associated with these malignancies is critical for accurate diagnosis, prognosis, ... ...

Abstract	Salivary gland neoplasms comprise a diverse group of tumors with different biological behaviors and clinical outcomes. Understanding the underlying molecular alterations associated with these malignancies is critical for accurate diagnosis, prognosis, and treatment strategies. Among the many biomarkers under investigation, epithelial cell adhesion molecule (EpCAM) has emerged as a promising candidate in salivary gland cancer research. This article aims to provide a comprehensive overview of the differential expression of EpCAM in salivary gland cancer and its potential correlation with the biological behavior of these tumors. The clinical characteristics of 65 patients with salivary gland malignancy of different histopathological subtypes were included. We report the differential expression of EpCAM and the relationship between the clinical and histopathologic features of these tumors. Regarding the evaluation of the effect of EpCAM expression on survival, in our study, we showed that tumors with high EpCAM expression had reduced disease-free survival (DFS) and overall survival (OS) (
Language	English
Publishing date	2023-08-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662336-5
ISSN	2075-4418
ISSN	2075-4418
DOI	10.3390/diagnostics13162652
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Article: The significance of double mandibular osteotomy for surgical treatment of large aneurysm of internal carotid artery above mandibular angle. A case report and literature review.

Tilaveridis, Ioannis / Tatsis, Dimitris / Venetis, Gregory / Trelopoulos, Georgios / Mylonas, Anastasios

Journal of surgical case reports

2022 Volume 2022, Issue 11, Page(s) rjac534

Abstract: The aim of this study is to report a case of an unusual large aneurysm of the internal carotid approached with a doubly mandibular osteotomy in order to prove the significance and the excellent result of the specified surgical procedure because of the ... ...

Abstract	The aim of this study is to report a case of an unusual large aneurysm of the internal carotid approached with a doubly mandibular osteotomy in order to prove the significance and the excellent result of the specified surgical procedure because of the cooperation of maxillofacial and vascular surgeons. The double mandibular osteotomy is described, as well as the bypass of the aneurysm and the anastomosis of the peripheral edges of the artery. The double mandibular osteotomy can deliver the internal carotid artery from the bifurcation to its entrance to the skull base through the carotid canal and can offer the opportunity to the vascular surgeon to perform the anastomosis easily, quickly and safely.
Language	English
Publishing date	2022-11-23
Publishing country	England
Document type	Case Reports
ZDB-ID	2580919-2
ISSN	2042-8812
ISSN	2042-8812
DOI	10.1093/jscr/rjac534
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Article: The Value of Three-Dimensional Modeling on Repositioning and Soft Tissue Filling in Microsurgical Reconstruction of Secondary Mandibular Defects: A Retrospective Study.

Tilaveridis, Ioannis / Pantazi, Glykeria / Venetis, Gregory / Ditsios, Konstantinos / Angelopoulos, Christos / Antoniades, Konstantinos

Cureus

2022 Volume 14, Issue 2, Page(s) e22336

Abstract: Purpose Secondary mandibular defect reconstruction is a challenging operation. It is performed rather rarely, as in most of the cases a primary reconstruction is preferable. Restoration of function and symmetry, in secondary reconstruction of mandibular ... ...

Abstract	Purpose Secondary mandibular defect reconstruction is a challenging operation. It is performed rather rarely, as in most of the cases a primary reconstruction is preferable. Restoration of function and symmetry, in secondary reconstruction of mandibular defects, requires accurate repositioning of segments and appropriate soft tissue filling. The purpose of this study is to estimate the value of three-dimensional (3D) digital modeling to meet the above requirements, in secondary microsurgical reconstruction of mandibular defects. Methods Five cases of mandibular defects, with various degrees of asymmetry and dysfunction, were restored secondarily, with fibula flaps, after virtual reconstruction on a 3D model derived from their computed tomography, with the utilization of CAD-CAM software. Software reproduced symmetrical 3D models by mirroring the healthy side. Occlusion was restored by fine adjustments on 3D models and finally a reconstruction plate was pre-bent on them, prior to its sterilization for use in surgery. Three out of the five cases received an osteo-cutaneous flap, while in the other two patients, an osseous flap was used. Lower face symmetry, mouth opening, and main patient's complaints were evaluated pre- and postoperatively to assess the value of the 3D modeling. Results All flaps survived. Hematoma occurred in two patients and was resolved after evacuation. In two patients, a fistula observed, was attributed to screw loosening, and treated after a surgical debridement and screw replacement. Intraoral exposure in the posterior part of the fibula flap was recorded in one patient, possibly from wound dehiscence due to tension of the intraoral tissue, and successfully covered with an ipsilateral nasolabial flap. The resulting symmetry and function were satisfactory in all the patients. Conclusion Secondary mandibular defects are often related with cosmetic disfigurement, misalignment of mandibular segments, and mandibular malfunction. For the correction of mandibular continuity, symmetry, and restoration of function, preoperative 3D modeling may be an important tool, according to our results.
Language	English
Publishing date	2022-02-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.22336
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Article: Unilateral Submandibular Gland Aplasia with Ipsilateral Sublingual Ranula - A Case Report.

Tatsis, Dimitris / Mantevas, Antonis / Kilmpasani, Maria / Karafoulidou, Ioanna / Venetis, Grigoris

Annals of maxillofacial surgery

2020 Volume 10, Issue 2, Page(s) 543–546

Abstract: Background: Congenital aplasia of major salivary glands is a very rare entity, especially if it concerns an ipsilateral aplasia in a nonsyndromic patient.: Key points from the case: The aim of this report is to present a case of an aplasia of the ... ...

Abstract	Background: Congenital aplasia of major salivary glands is a very rare entity, especially if it concerns an ipsilateral aplasia in a nonsyndromic patient. Key points from the case: The aim of this report is to present a case of an aplasia of the left submandibular gland, which was incidentally diagnosed during presurgical imaging for an ipsilateral sublingual ranula. Histopathological evidence of the lack of sublingual gland tissue in the excised specimen of the ranula is discussed. Main lessons to be learned from this case report: Unilateral submandibular aplasia has unknown etiology. Clinicians should be aware of this condition mainly to be able to differentially diagnose a hypertrophy/dysplasia of the contralateral or other major salivary glands, or when xerostomia is the main patient's symptom.
Language	English
Publishing date	2020-12-23
Publishing country	India
Document type	Case Reports
ZDB-ID	2696991-9
ISSN	2249-3816 ; 2231-0746
ISSN (online)	2249-3816
ISSN	2231-0746
DOI	10.4103/ams.ams_63_20
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Article ; Online: Peripheral Osteoma of the Mandibular Condyle-Case Series.

Tilaveridis, Ioannis / Katopodi, Theodora / Karakostas, Panagiotis / Venetis, Gregory / Dimitrakopoulos, Ioannis / Tilaveridis, Stavros / Tilaveridou, Sofia / Zarampouka, Katerina

Dentistry journal

2022 Volume 10, Issue 10

Abstract: The purpose of this article is to present four new cases of peripheral osteoma of the mandibular condyle and the literature review. A retrospective study of files from our Department of Oral and Maxillofacial Surgery over the last 6 years revealed four ... ...

Abstract	The purpose of this article is to present four new cases of peripheral osteoma of the mandibular condyle and the literature review. A retrospective study of files from our Department of Oral and Maxillofacial Surgery over the last 6 years revealed four cases of peripheral osteomas located in the area of the mandibular condyle. Diagnostic procedure included clinical, radiographic, and histologic criteria. Gardner's syndrome was excluded from patient history and clinical evaluation. One patient had only an aesthetic disturbance, with facial swelling, and the other three patients presented disturbances of the mandibular function, including deviation during mouth opening along with malocclusion. Three of the patients were male and one was female; all were of middle age (45-65 years old). The proposed surgical treatment was accepted by half of the patients, while the remaining half declined the operation after a confirmation of the diagnosis. Peripheral osteomas of the maxillofacial region are uncommon, and some cases with multiple osteomas are related to Gardner's syndrome. An osteoma of the mandibular condyle is very rare and surgical treatment is challenging for the surgeon with regards to the approach selection and the related complications. In the two cases that accepted the proposed surgical treatment, no recurrence and no complication was observed.
Language	English
Publishing date	2022-09-29
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2681351-8
ISSN	2304-6767 ; 2304-6767
ISSN (online)	2304-6767
ISSN	2304-6767
DOI	10.3390/dj10100182
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Article ; Online: The Combined Use of Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells Promotes Healing. A Review of Experimental Models and Future Perspectives.

Tatsis, Dimitris / Vasalou, Varvara / Kotidis, Efstathios / Anestiadou, Elissavet / Grivas, Ioannis / Cheva, Angeliki / Koliakos, Georgios / Venetis, Gregory / Pramateftakis, Manousos-George / Ouzounidis, Nikolaos / Angelopoulos, Stamatis

Biomolecules

2021 Volume 11, Issue 10

Abstract: Wound healing and tissue regeneration are a field of clinical medicine presenting high research interest, since various local and systematic factors can inhibit these processes and lead to an inferior result. New methods of healing enhancement constantly ...

Abstract	Wound healing and tissue regeneration are a field of clinical medicine presenting high research interest, since various local and systematic factors can inhibit these processes and lead to an inferior result. New methods of healing enhancement constantly arise, which, however, require experimental validation before their establishment in everyday practice. Platelet-rich plasma (PRP) is a well-known autologous factor that promotes tissue healing in various surgical defects. PRP derives from the centrifugation of peripheral blood and has a high concentration of growth factors that promote healing. Recently, the use of adipose-derived mesenchymal stem cells (ADMSCs) has been thoroughly investigated as a form of wound healing enhancement. ADMSCs are autologous stem cells deriving from fat tissue, with a capability of differentiation in specific cells, depending on the micro-environment that they are exposed to. The aim of the present comprehensive review is to record the experimental studies that have been published and investigate the synergistic use of PRP and ADMSC in animal models. The technical aspects of experimentations, as well as the major results of each study, are discussed. In addition, the limited clinical studies including humans are also reported. Future perspectives are discussed, along with the limitations of current studies on the long-term follow up needed on efficacy and safety.
MeSH term(s)	Adipose Tissue/transplantation ; Humans ; Intercellular Signaling Peptides and Proteins/genetics ; Intercellular Signaling Peptides and Proteins/therapeutic use ; Mesenchymal Stem Cell Transplantation ; Mesenchymal Stem Cells/cytology ; Platelet-Rich Plasma/metabolism ; Regeneration/genetics ; Wound Healing/genetics
Chemical Substances	Intercellular Signaling Peptides and Proteins
Language	English
Publishing date	2021-09-24
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2701262-1
ISSN	2218-273X ; 2218-273X
ISSN (online)	2218-273X
ISSN	2218-273X
DOI	10.3390/biom11101403
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Article ; Online: Efficacy of hyaluronic acid injections in patients with osteoarthritis of the temporomandibular joint. A comparative study.

Triantaffilidou, Katherine / Venetis, Gregory / Bika, Olga

The Journal of craniofacial surgery

2013 Volume 24, Issue 6, Page(s) 2006–2009

Abstract: The aim of the present study was to report the 1-year therapeutic outcome of intra-articular injections of high-molecular-weight hyaluronic acid (HA) without arthrocentesis in a group of 25 patients with osteoarthritis (OA) of the temporomandibular joint ...

Abstract	The aim of the present study was to report the 1-year therapeutic outcome of intra-articular injections of high-molecular-weight hyaluronic acid (HA) without arthrocentesis in a group of 25 patients with osteoarthritis (OA) of the temporomandibular joint (TMJ). The results were compared with those of a group of 10 patients with OA of the TMJ, treated with nonsteroidal anti-inflammatory drugs.Twenty-five patients (group A) underwent a cycle of 5 injections of HA into the TMJ. Ten patients (group B) underwent a therapy with nonsteroidal anti-inflammatory drugs for 1 month. The follow-up assessments after the end of treatment were at 1, 3, 6, and 12 months.Regarding the first follow-up (1 month), statistical analysis for all clinical parameters showed no significant differences (ie, beneficial effect for 2 groups) between groups A and B (P > 0.001). Significant statistical differences (ie, encouraging effect for group A) for all clinical parameters were recorded 1 year after the end of treatment between groups A and B (P < 0.001).A cycle of 5 intra-articular injections of HA without arthrocentesis for patients with OA of the TMJ is considered successful at 1-year follow-up period.
MeSH term(s)	Adjuvants, Immunologic/administration & dosage ; Aged ; Female ; Follow-Up Studies ; Humans ; Hyaluronic Acid/administration & dosage ; Injections, Intra-Articular ; Male ; Middle Aged ; Osteoarthritis/drug therapy ; Pain Measurement ; Range of Motion, Articular ; Temporomandibular Joint Disorders/drug therapy ; Viscosupplements/administration & dosage
Chemical Substances	Adjuvants, Immunologic ; Viscosupplements ; Hyaluronic Acid (9004-61-9)
Language	English
Publishing date	2013-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	1159501-2
ISSN	1536-3732 ; 1049-2275
ISSN (online)	1536-3732
ISSN	1049-2275
DOI	10.1097/SCS.0b013e3182a30566
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Article: Ischemic necrosis of nose and palate after embolization for epistaxis. A case report

Ntomouchtsis, A. / Venetis, G. / Zouloumis, L. / Lazaridis, N.

Oral and maxillofacial surgery

2010 Volume 14, Issue 2, Page(s) 129

Language	English
Document type	Article
ZDB-ID	2406731-3
ISSN	1865-1550
Database	Current Contents Medicine

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Article: The value of magnetic resonance arthrography of the temporomandibular joint in imaging disc adhesions and perforations.

Venetis, G / Pilavaki, M / Triantafyllidou, K / Papachristodoulou, A / Lazaridis, N / Palladas, P

Dento maxillo facial radiology

2011 Volume 40, Issue 2, Page(s) 84–90

Abstract: Objectives: This study attempted to validate MR arthrography (MRAr) of the temporomandibular joint (TMJ) in detecting the position, integrity and relations of the articular disc and retrodiscal tissue.: Methods: A total of 20 TMJs from 10 patients ... ...

Abstract	Objectives: This study attempted to validate MR arthrography (MRAr) of the temporomandibular joint (TMJ) in detecting the position, integrity and relations of the articular disc and retrodiscal tissue. Methods: A total of 20 TMJs from 10 patients with severe TMJ dysfunction underwent MRI and MRAr. A paramagnetic contrast medium was injected into the upper joint compartment to observe possible adhesions and/or leakage into the lower compartment. 15 TMJs were surgically or arthroscopically explored and restored. Results: MRAr was approximately in the same diagnostic value as MRI when locating position, but superior in detecting disc perforations (eight TMJs) and adhesions (seven TMJs) appearing together in four cases. Surgery confirmed radiological findings in all but one case, where arthroscopy and surgery failed to confirm a disc perforation indicated by MRAr. Conclusions: TMJ MRAr may simultaneously reveal adhesions and perforations. Sensitivity and the probability of false-positive results require further study.
MeSH term(s)	Adult ; Aged ; Arthrography ; Arthroscopy ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Temporomandibular Joint Disc/diagnostic imaging ; Temporomandibular Joint Disc/pathology ; Temporomandibular Joint Disc/surgery ; Temporomandibular Joint Disorders/diagnostic imaging ; Temporomandibular Joint Disorders/pathology ; Temporomandibular Joint Disorders/surgery ; Young Adult
Language	English
Publishing date	2011-01-14
Publishing country	England
Document type	Journal Article
ZDB-ID	221323-0
ISSN	1476-542X ; 0250-832X ; 0349-490X
ISSN (online)	1476-542X
ISSN	0250-832X ; 0349-490X
DOI	10.1259/dmfr/13255885
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