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  1. Article ; Online: Lipid peroxidation index of particulate matter: Novel metric for quantifying intrinsic oxidative potential and predicting toxic responses.

    Dey, Sumit K / Sugur, Kavya / Venkatareddy, Venkataramana G / Rajeev, Pradhi / Gupta, Tarun / Thimmulappa, Rajesh K

    Redox biology

    2021  Volume 48, Page(s) 102189

    Abstract: Using particulate matter (PM) mass as exposure metric does not reveal the intrinsic PM chemical characteristics or toxic potential, which is crucial for monitoring the sources of emission causing adverse health effects and developing risk mitigating ... ...

    Abstract Using particulate matter (PM) mass as exposure metric does not reveal the intrinsic PM chemical characteristics or toxic potential, which is crucial for monitoring the sources of emission causing adverse health effects and developing risk mitigating strategies. Oxidative stress and ensuing lipid peroxidation (LPO) in the lung are crucial underlying mechanisms of action by which PM drives cardiorespiratory disease. In the current study, we have postulated and demonstrated that the intrinsic potential of PM to elicit LPO, defined as "LPO index" as a novel approach for characterizing oxidative potential of PM (PM
    Language English
    Publishing date 2021-11-17
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2701011-9
    ISSN 2213-2317 ; 2213-2317
    ISSN (online) 2213-2317
    ISSN 2213-2317
    DOI 10.1016/j.redox.2021.102189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Development of

    Manjunath, Souparnika H / Nataraj, Prabhakaran / Swamy, Vikas H / Sugur, Kavya / Dey, Sumit K / Ranganathan, Veena / Daniel, Shyni / Leihang, Zonunsiami / Sharon, Veronica / Chandrashekharappa, Sandeep / Sajeev, Nithin / Venkatareddy, Venkataramana G / Chuturgoon, Anil / Kuppusamy, Gowthamarajan / Madhunapantula, SubbaRao V / Thimmulappa, Rajesh K

    Food & function

    2023  Volume 14, Issue 10, Page(s) 4734–4751

    Abstract: Pharmacological activation of nuclear factor erythroid 2 related factor 2 (NRF2) provides protection against several environmental diseases by inhibiting oxidative and inflammatory injury. Besides high in protein and minerals, ...

    Abstract Pharmacological activation of nuclear factor erythroid 2 related factor 2 (NRF2) provides protection against several environmental diseases by inhibiting oxidative and inflammatory injury. Besides high in protein and minerals,
    MeSH term(s) Mice ; Animals ; Antioxidants/pharmacology ; Moringa oleifera/chemistry ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Interleukin-6 ; Functional Food ; Tumor Necrosis Factor-alpha ; Anti-Inflammatory Agents/pharmacology ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Reactive Oxygen Species
    Chemical Substances Antioxidants ; NF-E2-Related Factor 2 ; Interleukin-6 ; Tumor Necrosis Factor-alpha ; Anti-Inflammatory Agents ; Plant Extracts ; Reactive Oxygen Species
    Language English
    Publishing date 2023-05-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2612033-1
    ISSN 2042-650X ; 2042-6496
    ISSN (online) 2042-650X
    ISSN 2042-6496
    DOI 10.1039/d3fo00572k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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