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Article: Persistent candida arthritis successfully treated with micafungin instillation and surgery. A case report

van Egmond, Jeroen C / Hunfeld, Nicole G.M / Rijnders, Bart J.A / Verhaar, Jan A.N

Medical mycology case reports. 2020 Mar., v. 27

2020

Abstract: We report a rare case of C. krusei knee arthritis treated with instillation of micafungin and arthroscopy. A 49-year-old man hospitalized for treatment of Acute Myeloid Leukemia developed knee arthritis with C. krusei. He was treated with a combination ... ...

Abstract	We report a rare case of C. krusei knee arthritis treated with instillation of micafungin and arthroscopy. A 49-year-old man hospitalized for treatment of Acute Myeloid Leukemia developed knee arthritis with C. krusei. He was treated with a combination of arthroscopic debridement, intravenous as well as intra-articular micafungin. Serum and intra-articular concentrations of micafungin were determined. After instillation of micafungin in the knee and arthroscopic debridement, the patient completely recovered.
Keywords	arthritis ; arthroscopy ; blood serum ; case studies ; debridement ; intravenous injection ; micafungin ; myeloid leukemia ; patients
Language	English
Dates of publication	2020-03
Size	p. 29-31.
Publishing place	Elsevier B.V.
Document type	Article
ISSN	2211-7539
DOI	10.1016/j.mmcr.2019.12.011
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Tendinopathy and osteoarthritis: a chance to kill two birds with one stone.

de Vos, Robert-Jan / van Osch, Gerjo Jvm / Bierma-Zeinstra, Sita M A / Verhaar, Jan An

British journal of sports medicine

2016 Volume 50, Issue 19, Page(s) 1164–1165

MeSH term(s)	Achilles Tendon/pathology ; Humans ; Musculoskeletal Pain/physiopathology ; Neuropeptides/physiology ; Osteoarthritis/physiopathology ; Tendinopathy/physiopathology
Chemical Substances	Neuropeptides
Language	English
Publishing date	2016-10
Publishing country	England
Document type	Editorial
ZDB-ID	600592-5
ISSN	1473-0480 ; 0306-3674
ISSN (online)	1473-0480
ISSN	0306-3674
DOI	10.1136/bjsports-2015-094909
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Article ; Online: Computer assisted surgery for knee ligament reconstruction.

Meuffels, Duncan E / Reijman, Max / Scholten, Rob Jpm / Verhaar, Jan An

The Cochrane database of systematic reviews

2011 , Issue 6, Page(s) CD007601

Abstract: Background: Anterior cruciate ligament (ACL) reconstruction is one of the most frequently performed orthopaedic procedures. The most common technical cause of reconstruction failure is graft malpositioning. Computer assisted surgery aims to aid graft ... ...

Abstract	Background: Anterior cruciate ligament (ACL) reconstruction is one of the most frequently performed orthopaedic procedures. The most common technical cause of reconstruction failure is graft malpositioning. Computer assisted surgery aims to aid graft placement. Objectives: To assess the effects of computer assisted reconstruction surgery versus conventional operating techniques for ACL or posterior cruciate ligament (PCL) deficient knees in adults. Search strategy: We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (October 2010), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2010, Issue 3), MEDLINE (1966 to March 2010), EMBASE (1980 to March 2010), CINAHL (1937 to March 2010), article references and prospective trial registers. Selection criteria: Randomised controlled trials (RCTs) and quasi-randomised controlled trials that compared computer assisted surgery (CAS) of the ACL and PCL with conventional operating techniques not involving CAS, were included. Data collection and analysis: Two authors independently screened search results, assessed risk of bias and extracted data. Where appropriate, data were pooled using risk ratios or mean differences, both with 95% confidence intervals. Main results: Four randomised controlled trials were included (266 participants). All involved ACL reconstructions performed by experienced surgeons. Risk of bias assessment was hampered by poor reporting of trial methods. Pooled data from two trials showed no statistically or clinically significant differences at two years or more follow-up in self-reported quality of life outcomes: International Knee Documentation Committee (IKDC) subjective scores (mean difference 2.05, 95% CI -2.16 to 6.25) and Lysholm scores (mean difference 2.05, 95% CI -2.16 to 6.25). A third trial also found a minimal difference in IKDC subjective scores (mean difference = 0.2). Pooled data from three trials for normal or nearly normal IKDC knee examination grades at final follow-up showed no significant differences between the two groups (risk ratio 1.01, 95% CI 0.96 to 1.06). No significant differences were found for other objective measures of knee function. The only adverse effects reported were some loss in range of motion in two versus three participants in one trial. CAS use was associated with longer operating times (range 9.3 to 26 minutes). Authors' conclusions: A favourable effect of computer assisted surgery for cruciate ligament reconstructions of the knee compared with conventional reconstructions could neither be demonstrated nor refuted. There is insufficient evidence to advise for or against the use of CAS. There is a need for improved reporting of future studies of this technology.
MeSH term(s)	Adult ; Anterior Cruciate Ligament/surgery ; Anterior Cruciate Ligament Injuries ; Humans ; Orthopedic Procedures/methods ; Posterior Cruciate Ligament/injuries ; Posterior Cruciate Ligament/surgery ; Randomized Controlled Trials as Topic ; Reconstructive Surgical Procedures/methods ; Surgery, Computer-Assisted/methods
Language	English
Publishing date	2011-06-15
Publishing country	England
Document type	Journal Article ; Meta-Analysis ; Review ; Systematic Review
ISSN	1469-493X
ISSN (online)	1469-493X
DOI	10.1002/14651858.CD007601.pub2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Trochanteric osteotomy versus posterolateral approach

van Biezen Frans C / Reijman Max / van der Grinten Margot / Verhaar Jan AN

BMC Musculoskeletal Disorders, Vol 12, Iss 1, p

function the first year post surgery. A pilot study

2011 Volume 138

Abstract: Abstract Background Although no prospective studies have compared functional results of trochanteric osteotomy and a non-trochanteric approach, most surgeons feel that trochanteric osteotomy is outdated in simple hip arthroplasty. Reasons not to perform ... ...

Abstract	Abstract Background Although no prospective studies have compared functional results of trochanteric osteotomy and a non-trochanteric approach, most surgeons feel that trochanteric osteotomy is outdated in simple hip arthroplasty. Reasons not to perform an osteotomy include the fear of longer rehabilitation and worse (final) functional outcome. Method This prospective study examines differences in rehabilitation between posterolateral and trochanteric approach one year post-surgery using questionnaires (WOMAC, SF-36, HHS) and functional tests (walking, climbing stairs, rising from sitting, and strength tests). Of the 109 patients 24 had a trochanteric osteotomy: the selected approach was based on the surgeon's preference. The trochanteric osteotomy group included more patients with developmental dysplasia of the hip. Before the start of the study no power analysis was performed. Results Data from the questionnaires showed no significant differences between the two groups at 3, 6 and 12-months follow-up. At 3-months follow-up patients in the trochanteric osteotomy group scored lower on the functional tests. This difference had disappeared at 6 and 12-months follow-up, except for abduction force which remained lower in the trochanteric osteotomy group in patients with a non union of the TO. Conclusion For simple hip arthroplasty an approach without osteotomy seems a logical choice. Although the power of this study is low, in experienced hands trochanteric osteotomy seems to give good functional results at 6-12 months post surgery if trochanteric union is obtained. Therefore, one should not hesitate to perform an osteotomy in difficult cases.
Keywords	Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Diseases of the musculoskeletal system ; RC925-935
Subject code	616
Language	English
Publishing date	2011-06-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Total knee arthroplasty after high tibial osteotomy. A systematic review

Furlan Andrea D / Reijman Max / van Raaij Tom M / Verhaar Jan AN

BMC Musculoskeletal Disorders, Vol 10, Iss 1, p

2009 Volume 88

Abstract: Abstract Background Previous osteotomy may compromise subsequent knee replacement, but no guidelines considering knee arthroplasty after prior osteotomy have been developed. We describe a systematic review of non-randomized studies to analyze the effect ... ...

Abstract	Abstract Background Previous osteotomy may compromise subsequent knee replacement, but no guidelines considering knee arthroplasty after prior osteotomy have been developed. We describe a systematic review of non-randomized studies to analyze the effect of high tibial osteotomy on total knee arthroplasty. Methods A computerized search for relevant studies published up to September 2007 was performed in Medline and Embase using a search strategy that is highly sensitive to find nonrandomized studies. Included were observational studies in which patients had total knee arthroplasty performed after prior high tibial osteotomy. Studies that fulfilled these criteria, were assessed for methodologic quality by two independent reviewers using the critical appraisal of observational studies developed by Deeks and the MINORS instrument. The study characteristics and data on the intervention, follow-up, and outcome measures, were extracted using a pre-tested standardized form. Primary outcomes were: knee range of motion, knee clinical score, and revision surgery. The grade of evidence was determined using the guidelines of the GRADE working group. Results Of the 458 articles identified using our search strategy, 17 met the inclusion criteria. Fifteen studies were cohort study with a concurrent control group, one was a historical cohort study and one a case-control study. Nine studies scored 50% or more on both methodological quality assessments. Pooling of the results was not possible due to the heterogeneity of the studies, and our analysis could not raise the overall low quality of evidence. No significant differences between primary total knee arthroplasty and total knee arthroplasty after osteotomy were found for knee range of motion in four out of six studies, knee clinical scores in eight out of nine studies, and revision surgery in eight out of eight studies after a median follow-up of 5 years. Conclusion Our analysis suggests that osteotomy does not compromise subsequent knee replacement. However, the low quality of evidence precludes solid clinical conclusions.
Keywords	Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Diseases of the musculoskeletal system ; RC925-935
Subject code	796
Language	English
Publishing date	2009-07-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Preventing running-related injuries using evidence-based online advice: the design of a randomised-controlled trial.

Fokkema, Tryntsje / de Vos, Robert-Jan / van Ochten, John M / Verhaar, Jan An / Davis, Irene S / Bindels, Patrick Je / Bierma-Zeinstra, Sita Ma / van Middelkoop, Marienke

BMJ open sport & exercise medicine

2017 Volume 3, Issue 1, Page(s) e000265

Abstract: Introduction: Running-related injuries (RRIs) are frequent and can lead to cessation of health promoting activities. Several risk factors for RRIs have been identified. However, no successful injury prevention programme has been developed so far. ... ...

Abstract	Introduction: Running-related injuries (RRIs) are frequent and can lead to cessation of health promoting activities. Several risk factors for RRIs have been identified. However, no successful injury prevention programme has been developed so far. Therefore, the aim of the present study is to investigate the effect of an evidence-based online injury prevention programme on the number of RRIs. Methods and analysis: The INSPIRE trial is a randomised-controlled trial with a 3-month follow-up. Both novice and more experienced runners, aged 18 years and older, who register for a running event (distances 5 km up to 42.195 km) will be asked to participate in this study. After completing the baseline questionnaire, participants will be randomised into either the intervention group or control group. Participants in the intervention group will get access to the online injury prevention programme. This prevention programme consists of information on evidence-based risk factors and advices to reduce the injury risk. The primary outcome measure is the number of self-reported RRIs in the time frame between registration for a running event and 1 month after the running event. Secondary outcome measures include the running days missed due to injuries, absence of work or school due to injuries, and the injury location. Ethics and dissemination: An exemption for a comprehensive application is obtained by the Medical Ethical Committee of the Erasmus University Medical Centre Rotterdam, Netherlands. The results of the study will be published in peer-reviewed journals and presented on international congresses. Trial registration number: NTR5998. Pre-results.
Language	English
Publishing date	2017-06-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2817580-3
ISSN	2055-7647
ISSN	2055-7647
DOI	10.1136/bmjsem-2017-000265
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Does MRI add value in general practice for patients with traumatic knee complaints? A 1-year randomised controlled trial.

Swart, Nynke M / van Oudenaarde, Kim / Bierma-Zeinstra, Sita Ma / Bloem, Hans Jl / van den Hout, Wilbert B / Algra, Paul R / Bindels, Patrick Je / Koes, Bart W / Nelissen, Rob Ghh / Verhaar, Jan An / Reijnierse, Monique / Luijsterburg, Pim Aj

British journal of sports medicine

2018 Volume 53, Issue 20, Page(s) 1285–1292

Abstract: Objective: To determine whether referral to MRI by the general practitioner (GP) is non-inferior to usual care (no access to MRI by GPs) in patients with traumatic knee complaints regarding knee-related daily function.: Methods: This was a ... ...

Abstract	Objective: To determine whether referral to MRI by the general practitioner (GP) is non-inferior to usual care (no access to MRI by GPs) in patients with traumatic knee complaints regarding knee-related daily function. Methods: This was a multicentre, non-inferiority randomised controlled trial with 1-year follow-up. GPs invited eligible patients during or after their consultation. Eligible patients (18-45 years) consulted a GP with knee complaints due to a trauma during the previous 6 months. Patients allocated to the MRI group received an MRI at (median) 7 (IQR 1-33) days after the baseline questionnaire. Patients in the usual care group received information on the course of knee complaints, and a referral to a physiotherapist or orthopaedic surgeon when indicated. The primary outcome measure was knee-related daily function measured with the Lysholm scale (0 to 100; 100=excellent function) over 1 year, with a non-inferiority margin of 6 points. Results: A total of 356 patients were included and randomised to MRI (n=179) or usual care (n=177) from November 2012 to December 2015. MRI was non-inferior to usual care concerning knee-related daily function during 1-year follow-up, for the intention-to-treat (overall adjusted estimate: 0.33; 95% CI -1.73 to 2.39) and per-protocol (overall adjusted estimate: 0.06; 95% CI -2.08 to 2.19) analysis. There were no differences between both groups in the amount of patients visiting other healthcare providers. Conclusion: MRI in general practice in patients with traumatic knee complaints was non-inferior to usual care regarding knee-related daily function during 1-year follow-up. Trial registration number: NTR3689.
MeSH term(s)	Adult ; Female ; General Practice ; Humans ; Knee Injuries/diagnostic imaging ; Magnetic Resonance Imaging ; Male ; Netherlands ; Referral and Consultation ; Young Adult
Language	English
Publishing date	2018-07-24
Publishing country	England
Document type	Equivalence Trial ; Journal Article ; Multicenter Study
ZDB-ID	600592-5
ISSN	1473-0480 ; 0306-3674
ISSN (online)	1473-0480
ISSN	0306-3674
DOI	10.1136/bjsports-2017-098932
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The effect of high tibial osteotomy on the results of total knee arthroplasty

Reijman Max / Bakker Wouter / van Raaij Tom M / Verhaar Jan AN

BMC Musculoskeletal Disorders, Vol 8, Iss 1, p

a matched case control study

2007 Volume 74

Abstract: Abstract Background We performed a matched case control study to assess the effect of prior high tibia valgus producing osteotomy on results and complications of total knee arthroplasty (TKA). Methods From 1996 until 2003 356 patients underwent all ... ...

Abstract	Abstract Background We performed a matched case control study to assess the effect of prior high tibia valgus producing osteotomy on results and complications of total knee arthroplasty (TKA). Methods From 1996 until 2003 356 patients underwent all cemented primary total knee replacement in our institution. Twelve patients with a history of 14 HTO were identified and matched to a control group of 12 patients with 14 primary TKA without previous HTO. The match was made for gender, age, date of surgery, body mass index, aetiology and type of prosthesis. Clinical and radiographic outcome were evaluated after a median duration of follow-up of 3.7 years (minimum, 2.3 years). The SPSS program was used for statistical analyses. Results The index group had more perioperative blood loss and exposure difficulties with one tibial tuberosity osteotomy and three patients with lateral retinacular releases. No such procedures were needed in the control group. Mid-term HSS, KSS and WOMAC scores were less favourable for the index group, but these differences were not significant. The tibial slope of patients with prior HTO was significantly decreased after this procedure. The tibial posterior inclination angle was corrected during knee replacement but posterior inclination was significantly less compared to the control group. No deep infection or knee component loosening were seen in the group with prior HTO. Conclusion We conclude that TKA after HTO seems to be technically more demanding than a primary knee arthroplasty, but clinical outcome was almost identical to a matched group that had no HTO previously.
Keywords	Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Diseases of the musculoskeletal system ; RC925-935
Subject code	796
Language	English
Publishing date	2007-08-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Functional capacity and actual daily activity do not contribute to patient satisfaction after total knee arthroplasty

Bussmann Johannes B / Reijman Max / de Groot Ingrid B / Vissers Maaike M / Stam Henk J / Verhaar Jan AN

BMC Musculoskeletal Disorders, Vol 11, Iss 1, p

2010 Volume 121

Abstract: Abstract Background After total knee arthroplasty (TKA) only 75-89% of patients are satisfied. Because patient satisfaction is a prime goal of all orthopaedic procedures, optimization of patient satisfaction is of major importance. Factors related to ... ...

Abstract	Abstract Background After total knee arthroplasty (TKA) only 75-89% of patients are satisfied. Because patient satisfaction is a prime goal of all orthopaedic procedures, optimization of patient satisfaction is of major importance. Factors related to patient satisfaction after TKA have been explored, but no studies have included two potentially relevant factors, i.e. the functional capacity of daily activities and actual daily activity. This present prospective study examines whether functional capacity and actual daily activity (in addition to an extensive set of potential factors) contribute to patient satisfaction six months after TKA. Methods A total of 44 patients were extensively examined preoperatively and six months post surgery. Functional capacity was measured with three capacity tests, focusing on walking, stair climbing, and chair rising. Actual daily activity was measured in the patient's home situation by means of a 48-hour measurement with an Activity Monitor. To establish which factors were related to patient satisfaction six months post surgery, logistic regression analyses were used to calculate odds ratios. Results Preoperative and postoperative functional capacity and actual daily activity had no relation with patient satisfaction. Preoperatively, only self-reported mental functioning was positively related to patient satisfaction. Postoperatively, based on multivariate analysis, only fulfilled expectations regarding pain and experienced pain six months post surgery were related to patient satisfaction. Conclusions Functional capacity and actual daily activity do not contribute to patient satisfaction after TKA. Patients with a better preoperative self-reported mental functioning, and patients who experienced less pain and had fulfilled expectations regarding pain postoperatively, were more often satisfied.
Keywords	Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Diseases of the musculoskeletal system ; RC925-935
Subject code	616
Language	English
Publishing date	2010-06-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Adverse effects of extra-articular corticosteroid injections

Brinks Aaltien / Koes Bart W / Volkers Aloysius CW / Verhaar Jan AN / Bierma-Zeinstra Sita MA

BMC Musculoskeletal Disorders, Vol 11, Iss 1, p

a systematic review

2010 Volume 206

Abstract: Abstract Background To estimate the occurrence and type of adverse effects after application of an extra-articular (soft tissue) corticosteroid injection. Methods A systematic review of the literature was made based on a PubMed and Embase search covering ...

Abstract	Abstract Background To estimate the occurrence and type of adverse effects after application of an extra-articular (soft tissue) corticosteroid injection. Methods A systematic review of the literature was made based on a PubMed and Embase search covering the period 1956 to January 2010. Case reports were included, as were prospective and retrospective studies that reported adverse events of corticosteroid injection. All clinical trials which used extra-articular corticosteroid injections were examined. We divided the reported adverse events into major (defined as those needing intervention or not disappearing) and minor ones (transient, not requiring intervention). Results The search yielded 87 relevant studies:44 case reports, 37 prospective studies and 6 retrospective studies. The major adverse events included osteomyelitis and protothecosis; one fatal necrotizing fasciitis; cellulitis and ecchymosis; tendon ruptures; atrophy of the plantar fat was described after injecting a neuroma; and local skin effects appeared as atrophy, hypopigmentation or as skin defect. The minor adverse events effects ranged from skin rash to flushing and disturbed menstrual pattern. Increased pain or steroid flare after injection was reported in 19 studies. After extra-articular injection, the incidence of major adverse events ranged from 0-5.8% and that of minor adverse events from 0-81%. It was not feasible to pool the risk for adverse effects due to heterogeneity of study populations and difference in interventions and variance in reporting. Conclusion In this literature review it was difficult to accurately quantify the incidence of adverse effects after extra-articular corticosteroid injection. The reported adverse events were relatively mild, although one fatal reaction was reported.
Keywords	Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Diseases of the musculoskeletal system ; RC925-935
Subject code	500
Language	English
Publishing date	2010-09-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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