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  1. Article: A Giant Scrotal Neurofibroma in a Child Masquerading as Filariasis: Uncommon Presentation of a Common Disease.

    Singh, Anurag / Singh, Gyanendra / Verma, Anuragani / Verma, Yogendra Narayan

    Prague medical report

    2024  Volume 125, Issue 1, Page(s) 56–61

    Abstract: Neurofibroma of the scrotum is a very uncommon benign neoplasm, specifically when it affects teenagers and is not associated with neurofibromatosis type I. To the best of our knowledge, only a couple of cases of neurofibroma in children have been ... ...

    Abstract Neurofibroma of the scrotum is a very uncommon benign neoplasm, specifically when it affects teenagers and is not associated with neurofibromatosis type I. To the best of our knowledge, only a couple of cases of neurofibroma in children have been documented. Here, we report a case study of a 17-year-old boy who had a giant scrotal lump for ten years masquerading clinically as filariasis. A provisional diagnosis of benign nerve sheath neoplasm was made based on cytology findings. The lump was surgically removed from the patient, and a histopathological and immunohistochemistry examination established the diagnosis of neurofibroma. The combined clinical, preoperative cytological, histological, and immunohistochemistry findings were not presented in the literature in any of the formerly documented cases of scrotal neurofibroma. The current case expands the spectrum of differential diagnoses for scrotal tumours that clinicians have previously observed.
    MeSH term(s) Male ; Adolescent ; Child ; Humans ; Scrotum/pathology ; Neurofibroma/diagnosis ; Neurofibroma/pathology ; Neurofibroma/surgery ; Neurofibromatosis 1/complications ; Neurofibromatosis 1/pathology ; Genital Neoplasms, Male/diagnosis ; Genital Neoplasms, Male/surgery ; Genital Neoplasms, Male/complications ; Filariasis/diagnosis ; Filariasis/complications ; Filariasis/pathology ; Nematode Infections/complications ; Nematode Infections/pathology
    Language English
    Publishing date 2024-02-21
    Publishing country Czech Republic
    Document type Case Reports ; Journal Article
    ZDB-ID 2148569-0
    ISSN 1214-6994
    ISSN 1214-6994
    DOI 10.14712/23362936.2024.5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Staphylococcus hemolyticus: The Most Common and Resistant Coagulase-Negative Staphylococcus Species Causing Bacteremia in North India.

    Verma, Anuragani / Kumar, Sanjay / Venkatesh, Vimala / Jain, Parul / Kalyan, RajKumar / Reddy, Himanshu

    Cureus

    2024  Volume 16, Issue 1, Page(s) e51680

    Abstract: Introduction: Coagulase-negative : Materials and methods: Inpatients with confirmed bacteremia defined as isolation of the same CoNS species with similar antibiograms from paired blood culture bottles, which were obtained from patients with at least ... ...

    Abstract Introduction: Coagulase-negative
    Materials and methods: Inpatients with confirmed bacteremia defined as isolation of the same CoNS species with similar antibiograms from paired blood culture bottles, which were obtained from patients with at least clinical evidence of infection, were included. The isolates obtained were studied for CoNS species distribution and antibiotic resistance patterns, and the corresponding patients were assessed for possible risk factors and outcomes.
    Results: A total of 170 CoNS isolates obtained from 85 patients were analyzed.
    Conclusion: Age-specific predisposition of CoNS species, high rates of methicillin resistance, and mortality in CoNS bacteremia are highlights of this study. To our knowledge, we are the first to study the age-related association of CoNS species.
    Language English
    Publishing date 2024-01-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.51680
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Ovarian aspergilloma in an immunocompetent patient masquerading as ovarian neoplasm.

    Singh, Gyanendra / Singh, Anurag / Verma, Anuragani / Verma, Yogendra / Kumar, Neeraj

    Archive of clinical cases

    2023  Volume 10, Issue 1, Page(s) 39–41

    Abstract: Aspergillus is a ubiquitous fungus that can cause a variety of clinical syndromes. It can lead to a spectrum of clinical presentations depending upon the severity of the disease, degree of immune compromisation, nature and intensity of inflammatory host ... ...

    Abstract Aspergillus is a ubiquitous fungus that can cause a variety of clinical syndromes. It can lead to a spectrum of clinical presentations depending upon the severity of the disease, degree of immune compromisation, nature and intensity of inflammatory host response. Ovarian aspergilloma is extremely unusual, only a few case reports have been described in the literature. Here, we report a case of ovarian aspergilloma which was masquerading as ovarian neoplasm on clinical examination and radiology. To the best of our knowledge, this is the first case report of isolated ovarian aspergillosis in an immunocompetent patient.
    Language English
    Publishing date 2023-03-27
    Publishing country Romania
    Document type Case Reports
    ZDB-ID 2788093-X
    ISSN 2360-6975 ; 2360-6975
    ISSN (online) 2360-6975
    ISSN 2360-6975
    DOI 10.22551/2023.38.1001.10237
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Prostate Tuberculosis Masquerading as Prostate Carcinoma: A Rare Case Report.

    Rawat, Shalini / Singh, Anurag / Singh, Akanksha / Verma, Anuragani / Sagar, Mala

    Cureus

    2022  Volume 14, Issue 11, Page(s) e30978

    Abstract: Genitourinary tuberculosis (GUTB), the second most frequent type of extrapulmonary tuberculosis (TB) in endemic regions, was initially described by Wildbolz in 1973. The prostate and epididymis are the first sites of male genital tuberculosis, followed ... ...

    Abstract Genitourinary tuberculosis (GUTB), the second most frequent type of extrapulmonary tuberculosis (TB) in endemic regions, was initially described by Wildbolz in 1973. The prostate and epididymis are the first sites of male genital tuberculosis, followed by the seminal vesicles and the testicles. Here, we describe a case of a 65-year-old male who presented with obstructive lower urinary tract symptoms (LUTS) for the previous six weeks. The digital rectal examination revealed prostatic enlargement with a firm and nodular surface. A high prostate-specific antigen level (88 ng/ml) was found in serum analysis. There was a suspicion of prostate cancer on the basis of clinical, radiological, and serological examination. In view of the suspicion of carcinoma, a prostate biopsy was performed, which revealed the proliferation of prostatic glandular and stromal elements with interspersed granulomas, necrosis, and aggregates of mature lymphoid cells. The histopathology findings were indicative of benign prostatic hyperplasia with granulomatous prostatitis. Ziehl-Neelsen (ZN) stain was negative for acid-fast bacilli. The cartridge-based nucleic acid amplification test (CBNAAT) for
    Language English
    Publishing date 2022-11-01
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.30978
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Outcomes in Oxacillinases β-Lactamases (OXA-48) and New Delhi Metallo-β-Lactamase (NDM-1)-Producing, Carbapenem-Resistant Klebsiella Pneumoniae Isolates Obtained From Bloodstream Infections.

    Verma, Anuragani / Jain, Parul / Tripathi, Piyush / Kalyan, Raj K / Verma, Sheetal / Venkatesh, Vimala

    Cureus

    2022  Volume 14, Issue 7, Page(s) e27197

    Abstract: Background: Carbapenemase-producing : Materials and methods: Klebsiella pneumoniae: Results: A total of 49 isolates were positive for one or more carbapenemase genes (30 {61.2%} for blaNDM gene only, 13 {26.5%)} for blaOXA48-like gene only, and ... ...

    Abstract Background: Carbapenemase-producing
    Materials and methods: Klebsiella pneumoniae
    Results: A total of 49 isolates were positive for one or more carbapenemase genes (30 {61.2%} for blaNDM gene only, 13 {26.5%)} for blaOXA48-like gene only, and six {12.2%} for both). The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of mCIM were found to be 77.6%, 100%, 100%, and 78.9%, respectively. Statistically significant differences were found in the AST pattern between the isolates with two genes. Increased MIC levels of colistin were observed, though they lay in the sensitive range. Mortality occurred in all six patients who were infected with CRKP harboring both the genes though no significant difference was observed in NDM and OXA-48 producing CRKP isolates.
    Conclusion: Surveillance of carbapenemase genes in a hospital setting is essential. The possible reasons for the low diagnostic accuracy of mCIM and differences in AST patterns are discussed.
    Language English
    Publishing date 2022-07-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.27197
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Seropositivity of Anti-SARS CoV2 IgG antibodies in health care workers of an Indian tertiary care hospital during COVID-19.

    Verma, Anuragani / Shukla, Suruchi / Verma, Anil K / Puri, Bipin / Jain, Amita

    Indian journal of medical microbiology

    2022  Volume 40, Issue 2, Page(s) 228–230

    Abstract: Purpose: Health care workers [HCW] are at a higher risk of infection SARS CoV2 infection due to frequent and close contact to patients with COVID-19.: Methods: Serum samples from 500 HCW's were tested for SARS CoV2 IgG antibodies in October 2020. A ... ...

    Abstract Purpose: Health care workers [HCW] are at a higher risk of infection SARS CoV2 infection due to frequent and close contact to patients with COVID-19.
    Methods: Serum samples from 500 HCW's were tested for SARS CoV2 IgG antibodies in October 2020. A questionnaire was used to collect demographic and clinical data. All these HCWs were tested for COVID-19, in 2nd week of September 2020, as a hospital policy.
    Results: Anti SARS CoV2 antibodies were detected in 128/ 500 [25.6%] HCWs. A total of 195/ 500 [39%] enrolled cases had already tested positive for Covid-19 at least once in last six months by RT-PCR. Sixty eight percent of HCWs with previous COVID-19 positivity by RT- PCR tested positive for Anti SARS CoV2 antibodies, whereas only 2.76% of asymptomatic HCWs tested positive. Of 121 anti SARS-CoV-2 IgG positive persons, 70 [57.85%] had CT value ​< ​25. Low CT value and asymptomatic cases had a strong reverse statistically significant association with SARS CoV2 IgG antibody positivity.
    Conclusions: We report that sero-conversion rate in HCWs is similar to that in general population suggesting that preventive practices used in hospitals are satisfactory. Cases with low viral counts in respiratory sample and asymptomatic cases have lower rate of seroconversion.
    MeSH term(s) Antibodies, Viral ; COVID-19 ; Health Personnel ; Humans ; Immunoglobulin G ; SARS-CoV-2 ; Seroepidemiologic Studies ; Tertiary Care Centers
    Chemical Substances Antibodies, Viral ; Immunoglobulin G
    Language English
    Publishing date 2022-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1038798-5
    ISSN 1998-3646 ; 0255-0857
    ISSN (online) 1998-3646
    ISSN 0255-0857
    DOI 10.1016/j.ijmmb.2022.02.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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