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  1. Book ; Thesis: Funktionelle Interaktionsstudien zur APP- und LRRTM-Proteinfamilie

    Vest, Alexandra

    2014  

    Author's details von Alexandra Vest
    Keywords Humangenetik ; Molekularbiologie ; Altern ; Alzheimerkrankheit
    Subject Alzheimer-Krankheit ; Alzheimersche Krankheit ; Alzheimer-Demenz ; Morbus Alzheimer ; Greisenblödsinn ; Alzheimer's Disease ; Alterungsprozess ; Altwerden ; Seneszenz ; Alterung ; Molekulare Biologie ; Medizinische Genetik ; Anthropogenetik ; Mensch ; Medizin
    Language German
    Size II, 100 Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Kaiserslautern, Techn. Univ., Diss., 2015
    HBZ-ID HT018587742
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2017 E 902 order for loan Magazin

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  2. Article: Strongyloides stercoralis Hyperinfection Syndrome in Pregnancy.

    Akers, Allison N / Vest, Adriana / Schenone, Claudio V / Rodriguez, Alejandro

    Cureus

    2023  Volume 15, Issue 8, Page(s) e43568

    Abstract: Strongyloidiasis is a parasitic infection with a high global burden of disease. Hyperinfection syndrome is a life-threatening complication that predominantly affects immunosuppressed individuals, such as those receiving corticosteroid treatment. Despite ... ...

    Abstract Strongyloidiasis is a parasitic infection with a high global burden of disease. Hyperinfection syndrome is a life-threatening complication that predominantly affects immunosuppressed individuals, such as those receiving corticosteroid treatment. Despite its worldwide prevalence, little is known about the clinical effects of this condition on the feto-maternal dyad during pregnancy. We present a case of placental abruption leading to preterm delivery in a pregnancy complicated by
    Language English
    Publishing date 2023-08-16
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.43568
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Thesis: Funktionelle Interaktionsstudien zur APP- und LRRTM-Proteinfamilie

    Vest, Alexandra

    2015  

    Author's details von Alexandra Vest
    Language German
    Size II, 100 Bl., Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Techn. Univ., Diss.--Kaiserslautern, 2015
    Note Zsfassung in dt. und engl. Sprache
    Database Former special subject collection: coastal and deep sea fishing

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    Inter-library loan at ZB MED

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  4. Book ; Thesis: Funktionelle Interaktionsstudien zur APP- und LRRTM-Proteinfamilie

    Vest, Alexandra

    2015  

    Author's details von Alexandra Vest
    Language German
    Size II, 100 Bl., Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Techn. Univ., Diss.--Kaiserslautern, 2015
    Note Zsfassung in dt. und engl. Sprache
    Database Special collection on veterinary medicine and general parasitology

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    Inter-library loan at ZB MED

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  5. Article ; Online: Immune mechanisms associated with sex-based differences in severe COVID-19 clinical outcomes.

    Arnold, Cosby G / Libby, Anne / Vest, Alexis / Hopkinson, Andrew / Monte, Andrew A

    Biology of sex differences

    2022  Volume 13, Issue 1, Page(s) 7

    Abstract: Background: Although biological males and females are equally likely to become infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), evidence has mounted that males experience higher severity and fatality compared to females. MAIN: ...

    Abstract Background: Although biological males and females are equally likely to become infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), evidence has mounted that males experience higher severity and fatality compared to females. MAIN: The objective of this review is to examine the existing literature on biological mechanisms underlying sex-based differences that could contribute to SARS-CoV-2 infection clinical outcomes. Sex-based differences in immunologic response and hormonal expression help explain the differences in coronavirus disease 2019 (COVID-19) outcomes observed in biological males and females. X inactivation facilitates a robust immune response to COVID-19 in females, who demonstrate a more profound antibody response and faster recovery when compared to males. Low testosterone levels also help explain the dysregulated inflammatory response and poor outcomes observed in some males with COVID-19. Gender differences in health expression and behaviors further compound these observed differences.
    Conclusion: Understanding the biology of sex-based differences in COVID-19 severity and mortality could help inform preventative measures, treatment decisions, and development of personalized, sex-specific therapies.
    MeSH term(s) COVID-19 ; Female ; Humans ; Immunity ; Male ; SARS-CoV-2 ; Sex Characteristics ; Sex Factors
    Language English
    Publishing date 2022-03-04
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 2587352-0
    ISSN 2042-6410 ; 2042-6410
    ISSN (online) 2042-6410
    ISSN 2042-6410
    DOI 10.1186/s13293-022-00417-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Accessing and utilizing clinical and genomic data from an electronic health record data warehouse.

    Arnold, Cosby G / Sonn, Brandon / Meyers, Frederick J / Vest, Alexis / Puls, Richie / Zirkler, Estelle / Edelmann, Michelle / Brooks, Ian M / Monte, Andrew A

    Translational medicine communications

    2023  Volume 8

    Abstract: Electronic health records (EHRs) and linked biobanks have tremendous potential to advance biomedical research and ultimately improve the health of future generations. Repurposing EHR data for research is not without challenges, however. In this paper, we ...

    Abstract Electronic health records (EHRs) and linked biobanks have tremendous potential to advance biomedical research and ultimately improve the health of future generations. Repurposing EHR data for research is not without challenges, however. In this paper, we describe the processes and considerations necessary to successfully access and utilize a data warehouse for research. Although imperfect, data warehouses are a powerful tool for harnessing a large amount of data to phenotype disease. They will have increasing relevance and applications in clinical research with growing sophistication in processes for EHR data abstraction, biobank integration, and cross-institutional linkage.
    Language English
    Publishing date 2023-03-02
    Publishing country England
    Document type Journal Article
    ISSN 2396-832X
    ISSN (online) 2396-832X
    DOI 10.1186/s41231-023-00140-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Characteristics of Emergency Medicine Specimen Bank Participants Compared to the Overall Emergency Department Population.

    Vest, Alexis / Sonn, Brandon / Puls, Richie / Arnold, Cosby / Devney, Zach / Ahmed, Arwah / Pallisard, Olivia / Monte, Andrew A

    The western journal of emergency medicine

    2023  Volume 24, Issue 2, Page(s) 312–321

    Abstract: Introduction: Biorepositories lack diversity both demographically and with regard to the clinical complaints of patients enrolled. The Emergency Medicine Specimen Bank (EMSB) seeks to enroll a diverse cohort of patients for discovery research in acute ... ...

    Abstract Introduction: Biorepositories lack diversity both demographically and with regard to the clinical complaints of patients enrolled. The Emergency Medicine Specimen Bank (EMSB) seeks to enroll a diverse cohort of patients for discovery research in acute care conditions. Our objective in this study was to determine the differences in demographics and clinical complaints between participants in the EMSB and the overall emergency department (ED) population.
    Methods: This was a retrospective analysis of participants of the EMSB and the entire UCHealth at University of Colorado Anschutz Medical Center (UCHealth AMC) ED population across three periods: peri-EMSB; post-EMSB; and COVID-19. We compared patients consented to the EMSB to the entire ED population to determine differences in age, gender, ethnicity, race, clinical complaints, and severity of illness. We used chi-square tests to compare categorical variables and the Elixhauser Comorbidity Index to determine differences in the severity of illness between the groups.
    Results: Between February 5, 2018-January 29, 2022, there were 141,670 consented encounters in the EMSB, representing 40,740 unique patients and over 13,000 blood samples collected. In that same time, the ED saw approximately 188,402 unique patients for 387,590 encounters. The EMSB had significantly higher rates of participation from the following: patients 18-59 years old (80.3% vs 77.7%); White patients (52.3% vs 47.8%), and women (54.8% vs 51.1%) compared to the overall ED population. The EMSB had lower rates of participation from patients ≥70 years, Hispanic patients, Asian patients, and men. The EMSB population had higher mean comorbidity scores. During the six months after Colorado's first COVID-19 case, the rate of consented patients and samples collected increased. The odds of consent during the COVID-19 study period were 1.32 (95% CI 1.26-1.39), and the odds of sample capture were 2.19 (95% CI 2.0-2.41).
    Conclusion: The EMSB is representative of the overall ED population for most demographics and clinical complaints.
    MeSH term(s) Adolescent ; Adult ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Acute Disease ; COVID-19/epidemiology ; Emergency Medicine ; Emergency Service, Hospital ; Retrospective Studies ; Tissue Banks ; Patient Participation
    Language English
    Publishing date 2023-02-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2375700-0
    ISSN 1936-9018 ; 1936-9018
    ISSN (online) 1936-9018
    ISSN 1936-9018
    DOI 10.5811/westjem.2022.11.57981
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Osseointegrated implant-retained auricular prosthesis constructed using cone-beam computed tomography and a prosthetically driven digital workflow: a case report.

    Domingue, Daniel / Glenn, Nathan Cory / Vest, Allison / White, James R

    Clinical case reports

    2020  Volume 9, Issue 1, Page(s) 37–45

    Abstract: Prosthetically driven workflows using CBCT, digital optical scanning, 3D-printed molds and frameworks, and dental implant component attachments to osseointegrated fixtures can produce anatomically accurate, esthetic, durable silicone ear replacements. ...

    Abstract Prosthetically driven workflows using CBCT, digital optical scanning, 3D-printed molds and frameworks, and dental implant component attachments to osseointegrated fixtures can produce anatomically accurate, esthetic, durable silicone ear replacements.
    Language English
    Publishing date 2020-11-17
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.3386
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Une dégénérescence marginale de Terrien chez une enfant de 6 ans : à propos d’un cas.

    Vest, A / Jean-Charles, A / Bechet, L / Plasse, N / Paul, N / Merle, H

    Journal francais d'ophtalmologie

    2018  Volume 41, Issue 9, Page(s) e433–e435

    Title translation Terrien's marginal corneal degeneration in a six-year-old girl: A case report.
    MeSH term(s) Child ; Corneal Dystrophies, Hereditary/diagnosis ; Diagnosis, Differential ; Female ; Humans ; Slit Lamp Microscopy ; Tomography, Optical Coherence
    Language French
    Publishing date 2018-11-01
    Publishing country France
    Document type Case Reports ; Letter
    ZDB-ID 426662-6
    ISSN 1773-0597 ; 0181-5512
    ISSN (online) 1773-0597
    ISSN 0181-5512
    DOI 10.1016/j.jfo.2018.01.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1417: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Vaccination Hesitancy and Postacute Sequelae of SARS-CoV-2: Is It Time to Reconsider?

    Arnold, Cosby G / Monte, Andrew A / Littlefield, Katherine / Vest, Alexis / Palmer, Brent E

    Viral immunology

    2021  Volume 34, Issue 10, Page(s) 666–668

    MeSH term(s) COVID-19/complications ; COVID-19/epidemiology ; COVID-19/physiopathology ; COVID-19/therapy ; COVID-19/virology ; COVID-19 Vaccines/administration & dosage ; COVID-19 Vaccines/immunology ; Humans ; SARS-CoV-2/immunology ; SARS-CoV-2/isolation & purification ; SARS-CoV-2/pathogenicity ; United States/epidemiology ; Vaccination Hesitancy/psychology ; Vaccination Hesitancy/statistics & numerical data
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-09-03
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 639075-4
    ISSN 1557-8976 ; 0882-8245
    ISSN (online) 1557-8976
    ISSN 0882-8245
    DOI 10.1089/vim.2021.0126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2227: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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