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  1. Article ; Online: Chronic cardiac disease should be considered when using left ventricular dimensions to assess volume status and fluid responsiveness.

    Rajendram, Rajkumar / Via, Gabriele / Tavazzi, Guido / Melniker, Lawrence / Hussain, Arif

    Intensive care medicine

    2022  Volume 48, Issue 12, Page(s) 1822–1824

    MeSH term(s) Humans ; Stroke Volume ; Cardiac Output ; Heart Ventricles/diagnostic imaging ; Heart Diseases ; Fluid Therapy/methods ; Hemodynamics
    Language English
    Publishing date 2022-10-05
    Publishing country United States
    Document type Letter
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-022-06895-8
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    Zs.A 1089: Show issues Location:
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  2. Article ; Online: Dynamic right-to-left interatrial shunt may complicate severe COVID-19.

    Rajendram, Rajkumar / Hussain, Arif / Mahmood, Naveed / Via, Gabriele

    BMJ case reports

    2021  Volume 14, Issue 10

    Abstract: Right-to-left (RTL) interatrial shunt (IAS) may complicate select cases of COVID-19 pneumonia. We describe the use of serial imaging to monitor shunt in critically ill patients. A 52-year-old man presented with COVID-19 pneumonia. Hypoxia worsened ... ...

    Abstract Right-to-left (RTL) interatrial shunt (IAS) may complicate select cases of COVID-19 pneumonia. We describe the use of serial imaging to monitor shunt in critically ill patients. A 52-year-old man presented with COVID-19 pneumonia. Hypoxia worsened despite maximal medical therapy and non-invasive ventilation. On day 8, saline microbubble contrast-enhanced transthoracic echocardiography revealed a patent foramen ovale (PFO) with RTLIAS. Invasive ventilation was initiated the next day. The course was complicated by intermittent severe desaturation without worsening aeration or haemodynamic instability, so PFO closure was considered. However, on day 12, saline microbubble contrast-enhanced transoesophageal echocardiography excluded RTLIAS. The patient was extubated on day 27 and discharged home 12 days later. Thus, RTLIAS may be dynamic and changes can be detected and monitored by serial imaging. Bedside echocardiography with saline microbubble contrast, a simple, minimally invasive bedside test, may be useful in the management of patients with severe hypoxia.
    MeSH term(s) COVID-19 ; Echocardiography ; Echocardiography, Transesophageal ; Foramen Ovale, Patent/complications ; Foramen Ovale, Patent/diagnostic imaging ; Foramen Ovale, Patent/surgery ; Humans ; Male ; Middle Aged ; SARS-CoV-2
    Language English
    Publishing date 2021-10-01
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2021-245301
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  3. Article: Diagnosis of diastolic dysfunction in the emergency department: really at reach for minimally trained sonologists? A call for a wise approach to heart failure with preserved ejection fraction diagnosis in the ER.

    Via, Gabriele / Tavazzi, Guido

    Critical ultrasound journal

    2018  Volume 10, Issue 1, Page(s) 26

    Language English
    Publishing date 2018-10-08
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2673587-8
    ISSN 2036-7902 ; 2036-3176
    ISSN (online) 2036-7902
    ISSN 2036-3176
    DOI 10.1186/s13089-018-0107-2
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  4. Article ; Online: The right ventricle after cardiopulmonary bypass: new insights on its adaptive physiology.

    Via, Gabriele / Tavazzi, Guido / Bendjelid, Karim

    Journal of clinical monitoring and computing

    2020  Volume 34, Issue 6, Page(s) 1133–1134

    MeSH term(s) Cardiac Surgical Procedures/adverse effects ; Cardiopulmonary Bypass ; Heart Ventricles/diagnostic imaging ; Humans
    Language English
    Publishing date 2020-03-10
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 1418733-4
    ISSN 1573-2614 ; 1387-1307 ; 0748-1977
    ISSN (online) 1573-2614
    ISSN 1387-1307 ; 0748-1977
    DOI 10.1007/s10877-020-00497-9
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    Zs.A 2054: Show issues Location:
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  5. Article ; Online: Point of care ultrasonography: And now, where shall we go in perioperative medicine?

    Zieleskiewicz, Laurent / Ortner, Clemens / Bruckert, Vincent / Via, Gabriele / Bouvet, Lionel

    Anaesthesia, critical care & pain medicine

    2021  Volume 41, Issue 1, Page(s) 101014

    MeSH term(s) Anesthesiology ; Humans ; Perioperative Medicine ; Point-of-Care Systems ; Ultrasonography
    Language English
    Publishing date 2021-12-23
    Publishing country France
    Document type Editorial ; Comment
    ISSN 2352-5568
    ISSN (online) 2352-5568
    DOI 10.1016/j.accpm.2021.101014
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  6. Article ; Online: Airway ultrasound to detect subglottic secretion above endotracheal tube cuff.

    Adi, Osman / Fong, Chan Pei / Sallehuddin, Roslanuddin Mohd / Ahmad, Azma Haryaty / Sum, Kok Meng / Yusof, Zulrushdi Md / Via, Gabriele / Tavazzi, Guido

    The ultrasound journal

    2023  Volume 15, Issue 1, Page(s) 23

    Abstract: Background: Subglottic secretion had been proven as one of the causes of microaspiration and increased risk of ventilator-associated pneumonia (VAP). The role of ultrasound to detect subglottic secretion has not yet been established.: Purpose: The ... ...

    Abstract Background: Subglottic secretion had been proven as one of the causes of microaspiration and increased risk of ventilator-associated pneumonia (VAP). The role of ultrasound to detect subglottic secretion has not yet been established.
    Purpose: The purpose of this study is to determine the sensitivity and specificity of upper airway ultrasound (US) in the detection of subglottic secretions as compared to computed tomography (CT) scanning.
    Material and methods: A prospective observational study was carried out in adult trauma patients requiring mechanical ventilation and cervical CT scan. All patients had an endotracheal tube cuff-pressure maintained between 20 and 30 cm H
    Results: Fifty participants were consecutively included. Subglottic secretions were detected in 31 patients using upper airway US. The sensitivity and specificity of upper airway US in detecting subglottic secretion were 96.7% and 90%, respectively (PPV 93.5%, NPV 94.7%). 18 (58%) patients with subglottic secretions developed VAP during their ICU stay (p = 0.01). The area under the receiver operating curve (AUROC) was 0.977 (95% CI 0.936-1.00).
    Conclusions: Upper airway US is a useful tool for detecting subglottic secretions with high sensitivity and specificity.
    Clinical implications: This study shows: 1. Upper airway US may aid in detecting subglottic secretions, which are linked to VAP. 2. Detecting subglottic secretions at the bedside aids in determining the best frequency of subglottic aspiration to clean the subglottic trachea. 3. Upper airway US may also aid in detecting the correct ETT position. Trial registration Clinicaltrials.gov.
    Clinicaltrials: gov identifier NCT04739878 Date of registration 2nd May 2021 URL of trial registry record https://clinicaltrials.gov/ct2/show/NCT04739878 .
    Language English
    Publishing date 2023-05-06
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2965029-X
    ISSN 2524-8987 ; 2036-3176
    ISSN (online) 2524-8987
    ISSN 2036-3176
    DOI 10.1186/s13089-023-00318-5
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  7. Article ; Online: What's new in ultrasound-based assessment of organ perfusion in the critically ill: expanding the bedside clinical monitoring window for hypoperfusion in shock.

    Corradi, Francesco / Via, Gabriele / Tavazzi, Guido

    Intensive care medicine

    2019  Volume 46, Issue 4, Page(s) 775–779

    MeSH term(s) Critical Illness ; Humans ; Perfusion ; Shock ; Ultrasonography
    Language English
    Publishing date 2019-10-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-019-05791-y
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    Zs.A 1089: Show issues Location:
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  8. Article ; Online: Renal Doppler-Based Assessment of Regional Organ Perfusion in the Critically Ill Patient.

    Corradi, Francesco / Brusasco, Claudia / Via, Gabriele / Tavazzi, Guido / Forfori, Francesco

    Shock (Augusta, Ga.)

    2020  Volume 55, Issue 6, Page(s) 842–843

    MeSH term(s) Critical Illness ; Humans ; Kidney/diagnostic imaging ; Perfusion
    Language English
    Publishing date 2020-05-26
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1185432-7
    ISSN 1540-0514 ; 1073-2322
    ISSN (online) 1540-0514
    ISSN 1073-2322
    DOI 10.1097/SHK.0000000000001571
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    Zs.A 3985: Show issues Location:
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  9. Article ; Online: Contextualizing cardiac dysfunction in critically ill patients with COVID-19.

    Tavazzi, Guido / Corradi, Francesco / Mojoli, Francesco / Forfori, Francesco / Via, Gabriele

    Minerva anestesiologica

    2020  Volume 86, Issue 12, Page(s) 1340–1345

    Abstract: Acute cardiac injury incidence in COVID-19 is about 13 times higher in the Intensive Care Unit (ICU)/severely ill than in less critical patients. Patients with cardiovascular comorbidities seem to be more prone to develop higher acuity of the infection, ... ...

    Abstract Acute cardiac injury incidence in COVID-19 is about 13 times higher in the Intensive Care Unit (ICU)/severely ill than in less critical patients. Patients with cardiovascular comorbidities seem to be more prone to develop higher acuity of the infection, and myocardial injury has been reported amongst them in up to 15% of those hospitalized and up to 30% of ICU-admitted ones. The symptoms of over ischemia/heart failure may be challenging to distinguish as dyspnea and chest discomfort overlap with those due to COVID-19. Therefore, beside close monitoring with electrocardiography, biomarkers and, in case of demonstrated cardiac involvement, echocardiography, strategies to improve myocardial oxygen delivery should be promptly applied. The cytokine release with complement and iNO dysregulation are established mechanisms potentially leading to sepsis-related cardiomyopathy, making sepsis per se one of the potential mechanism leading to acute cardiac injury in COVID-19 patients. Moreover, the hyper-inflammation with endothelial dysfunction is likely be responsible of both pulmonary in-situ platelet aggregation and deep thrombosis potentially leading to severe pulmonary embolism and right ventricular failure. Besides the customary antithrombotic prophylaxis for critical patients, D-dimer levels and tighter coagulation monitoring are recommended and should guide the choice for anticoagulation treatment. We summarize the current knowledge regarding cardiovascular involvement in patient with COVID-19.
    MeSH term(s) Angiotensin-Converting Enzyme 2/genetics ; COVID-19/complications ; Critical Illness/therapy ; Heart Diseases/etiology ; Heart Diseases/therapy ; Humans ; Ventricular Dysfunction, Right/etiology ; Ventricular Dysfunction, Right/therapy
    Chemical Substances ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
    Keywords covid19
    Language English
    Publishing date 2020-11-11
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 123584-9
    ISSN 1827-1596 ; 0026-4717 ; 0375-9393
    ISSN (online) 1827-1596
    ISSN 0026-4717 ; 0375-9393
    DOI 10.23736/S0375-9393.20.14859-4
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    Zs.MO 192: Show issues

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  10. Article ; Online: COVID-19, End-Stage Heart Failure and Outcome: A Word of Caution in Determining the Causal Link.

    Tavazzi, Guido / Corradi, Francesco / Mojoli, Francesco / Hussain, Arif / Via, Gabriele

    JACC. Heart failure

    2020  Volume 8, Issue 7, Page(s) 598–599

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Heart Failure ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2020.04.014
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