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  1. Article: Sewage sludge as organic matrix in the manufacture of organomineral fertilizers: Physical forms, environmental risks, and nutrients recycling

    Rodrigues, Mayra Maniero / Viana, Douglas Gomes / Oliveira, Fernando Carvalho / Alves, Marcelo Corrêa / Regitano, Jussara Borges

    Journal of cleaner production. 2021 Sept. 01, v. 313

    2021  

    Abstract: The use of organomineral fertilizers (OMFs) has grown worldwide, mainly in tropical conditions, combining economics and environmental management. Our study used a sewage sludge (SS) rich in Zn as the organic matrix in the manufacture of OMFs, with the ... ...

    Abstract The use of organomineral fertilizers (OMFs) has grown worldwide, mainly in tropical conditions, combining economics and environmental management. Our study used a sewage sludge (SS) rich in Zn as the organic matrix in the manufacture of OMFs, with the following objectives: i) to select the best OMF physical form; ii) to evaluate environmental risks associated with their application; iii) to recycle SS nutrients for soybean (Glycine max) production; iv) to verify their benefits to soil microbial activity and other soil functions. For each soil individually, a clay and a sandy clay loam, six treatments were tested: control (CT, without fertilization); mineral fertilization (MF); MF plus Zn and B (MFZₙ ₊ B); and three distinct physical forms for the OMFs [powder (Pw), granule (G), and pellet (Pt)], all calculated to provide 100 kg of P₂O₅ and performed in four blocks. Amending SS-OMFs did not represent an environmental risk in terms of spreading pathogens and hazardous trace elements. In comparison with MFs, SS-OMFs enhanced nutrients accumulation, pod numbers, and nodulation, as well as soil microbial activity, but did not affect shoot and root dry masses and enzymatic activities at early stages of soybean development (60 d after planting). They were also capable to supply Zn and B to plants and their distinct physical forms did not affect microbiological indicators of soil quality or nutrients accumulation in plant tissues. Overall, SS-OMFs seems to be a promising alternative for sustainable use of SSs in soybeans avoiding their disposal in landfills, but field studies are still needed to ratify the findings under more realistic conditions.
    Keywords Glycine max ; clay ; manufacturing ; microbial activity ; nodulation ; risk ; sandy clay loam soils ; sewage sludge ; soil quality ; soybeans
    Language English
    Dates of publication 2021-0901
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 0959-6526
    DOI 10.1016/j.jclepro.2021.127774
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Sulfadiazine dissipation in acidic tropical soils.

    Reia, Marina Yasbek / Leal, Rafael Marques Pereira / Tornisielo, Valdemar Luiz / Viana, Douglas Gomes / Regitano, Jussara Borges

    Environmental science and pollution research international

    2020  Volume 27, Issue 17, Page(s) 21243–21251

    Abstract: Sulfadiazine (SDZ) residues have been detected in manured soils as well as their adjacent water resources, but its behavior is still poorly understood in acidic tropical soils. This research aimed to evaluate sorption, leaching, and biodegradation ... ...

    Abstract Sulfadiazine (SDZ) residues have been detected in manured soils as well as their adjacent water resources, but its behavior is still poorly understood in acidic tropical soils. This research aimed to evaluate sorption, leaching, and biodegradation of
    MeSH term(s) Anti-Bacterial Agents ; Brazil ; Manure ; Soil ; Soil Pollutants/analysis ; Sulfadiazine
    Chemical Substances Anti-Bacterial Agents ; Manure ; Soil ; Soil Pollutants ; Sulfadiazine (0N7609K889)
    Language English
    Publishing date 2020-04-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-020-08456-2
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  3. Article ; Online: Crotalaria juncea L. enhances the bioremediation of sulfentrazone-contaminated soil and promotes changes in the soil bacterial community.

    de Souza, Adijailton Jose / Santos, Esequiel / Ribeiro, Fábio Pires / de Araújo Pereira, Arthur Prudêncio / Viana, Douglas Gomes / da Silva Coelho, Irene / Filho, Fernando Barboza Egreja / Santaren, Karen Caroline Ferreira

    Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology

    2023  Volume 54, Issue 3, Page(s) 2319–2331

    Abstract: Sulfentrazone (STZ) is an efficient tool for the pre- and post-emergence control of monocotyledonous and dicotyledonous weeds in fields of crops such as pineapple, coffee, sugarcane, citrus, eucalyptus, tobacco, and soybean. However, this herbicide ... ...

    Abstract Sulfentrazone (STZ) is an efficient tool for the pre- and post-emergence control of monocotyledonous and dicotyledonous weeds in fields of crops such as pineapple, coffee, sugarcane, citrus, eucalyptus, tobacco, and soybean. However, this herbicide persists in the soil, causing phytotoxicity in the subsequent crop. Therefore, it is important to use efficient strategies for the remediation of STZ-contaminated areas. The aim of this study was to evaluate the effects of Crotalaria juncea L. on the remediation of STZ-contaminated soil and on the microbial activity and bacterial community structure therein. The study was conducted in three stages: (i) cultivation of C. juncea in soil contaminated with 200, 400, and 800 g ha
    MeSH term(s) Soil Microbiology ; Crotalaria/metabolism ; Biodegradation, Environmental ; Sulfonamides/metabolism ; Triazoles/metabolism
    Chemical Substances N-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl)phenyl)methanesulfonamide (7TY7WT1599) ; Sulfonamides ; Triazoles
    Language English
    Publishing date 2023-08-14
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2017175-4
    ISSN 1678-4405 ; 1517-8382
    ISSN (online) 1678-4405
    ISSN 1517-8382
    DOI 10.1007/s42770-023-01064-5
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  4. Article ; Online: The role of land use, management, and microbial diversity depletion on glyphosate biodegradation in tropical soils.

    Martins, Guilherme Lucio / de Souza, Adijailton Jose / Osti, Júlio Flavio / Gontijo, Júlia Brandão / Cherubin, Maurício Roberto / Viana, Douglas Gomes / Rodrigues, Mayra Maniero / Tornisielo, Valdemar Luiz / Regitano, Jussara Borges

    Environmental research

    2023  Volume 231, Issue Pt 1, Page(s) 116178

    Abstract: Land use and management changes affect the composition and diversity of soil bacteria and fungi, which in turn may alter soil health and the provision of key ecological functions, such as pesticide degradation and soil detoxification. However, the extent ...

    Abstract Land use and management changes affect the composition and diversity of soil bacteria and fungi, which in turn may alter soil health and the provision of key ecological functions, such as pesticide degradation and soil detoxification. However, the extent to which these changes affect such services is still poorly understood in tropical agroecosystems. Our main goal was to evaluate how land-use (tilled versus no-tilled soil), soil management (N-fertilization), and microbial diversity depletion [tenfold (D1 = 10
    MeSH term(s) Soil ; Ecosystem ; Soil Microbiology ; Agriculture ; Bacteria/genetics ; Bacteria/metabolism ; Glyphosate
    Chemical Substances Soil
    Language English
    Publishing date 2023-05-16
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2023.116178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: In situ barium phytoremediation in flooded soil using Typha domingensis under different planting densities.

    Viana, Douglas Gomes / Egreja Filho, Fernando Barboza / Pires, Fábio Ribeiro / Soares, Matheus Bortolanza / Ferreira, Amanda Duim / Bonomo, Robson / Martins, Luiz Fernando

    Ecotoxicology and environmental safety

    2021  Volume 210, Page(s) 111890

    Abstract: The management of initial planting density can be a strategy to increase barium phytoextraction from soil, reducing the time required for soil decontamination. To delimit the ideal planting density for barium (Ba) phytoremediation using Typha domingensis, ...

    Abstract The management of initial planting density can be a strategy to increase barium phytoextraction from soil, reducing the time required for soil decontamination. To delimit the ideal planting density for barium (Ba) phytoremediation using Typha domingensis, we conducted a 300-day experiment in an area accidentally contaminated with barite. Four initial planting densities were tested: 4, 8, 12, and 16 plantsm
    MeSH term(s) Barium/metabolism ; Biodegradation, Environmental ; Biomass ; Floods ; Soil Pollutants/metabolism ; Typhaceae/metabolism
    Chemical Substances Soil Pollutants ; Barium (24GP945V5T)
    Language English
    Publishing date 2021-01-10
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 436536-7
    ISSN 1090-2414 ; 0147-6513
    ISSN (online) 1090-2414
    ISSN 0147-6513
    DOI 10.1016/j.ecoenv.2021.111890
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Synthesis and In Vitro and Silico Anti-inflammatory Activity of New Thiazolidinedione-quinoline Derivatives.

    Barbosa da Silva, Sandra Elizabeth / da Silva Moura, José Arion / Branco Júnior, Jeann Fabiann / Teixeira de Moraes Gomes, Paulo André / Silva de Paula, Simão Kalebe / Francisco Viana, Douglas Carvalho / Vasconcelos de Freitas Ramalho, Eduardo Augusto / Gomes, João Victor de Melo / Pereira, Michelly Cristiny / Pitta, Maira Galdino da Rocha / Pitta, Ivan da Rocha / Pitta, Marina Galdino da Rocha

    Current topics in medicinal chemistry

    2024  

    Abstract: Background: Inflammation is a series of complex defense-related reactions. The inflammation cascade produces various pro-inflammatory mediators. Unregulated production of these pro-inflammatory mediators can lead to a wide range of diseases, including ... ...

    Abstract Background: Inflammation is a series of complex defense-related reactions. The inflammation cascade produces various pro-inflammatory mediators. Unregulated production of these pro-inflammatory mediators can lead to a wide range of diseases, including rheumatoid arthritis, sepsis, and inflammatory bowel disease. In the literature, the anti-inflammatory action of quinoline and thiazolidinedione nuclei are well established, alone, and associated with other nuclei. The synthesis of hybrid molecules is a strategy for obtaining more efficient molecules due to the union of pharmacophoric nuclei known to be related to pharmacological activity.
    Objective: Based on this, this work presents the synthesis of thiazolidinedione-quinoline molecular hybrids and their involvement in the modulation of cytokines involved in the inflammatory reaction cascade.
    Methods: After synthesis and characterization, the compounds were submitted to cell viability test (MTT), ELISA IFN-γ and TNF-α, adipogenic differentiation, and molecular docking assay with PPARy and COX-2 targets.
    Results: LPSF/ZKD2 and LPSF/ZKD7 showed a significant decrease in the concentration of IFN- γ and TNF-α, with a dose-dependent behavior. LPSF/ZKD4 at a concentration of 50 μM significantly reduced IL-6 expression. LPSF/ZKD4 demonstrates lipid accumulation with significant differences between the untreated and negative control groups, indicating a relevant agonist action on the PPARγ receptor. Molecular docking showed that all synthesized compounds have good affinity with PPARγ e COX-2, with binding energy close to -10,000 Kcal/mol.
    Conclusion: These results demonstrate that the synthesis of quinoline-thiazolidinedione hybrids may be a useful strategy for obtaining promising candidates for new anti-inflammatory agents.
    Language English
    Publishing date 2024-03-21
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2064823-6
    ISSN 1873-4294 ; 1568-0266
    ISSN (online) 1873-4294
    ISSN 1568-0266
    DOI 10.2174/0115680266295582240318060802
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  7. Article: Effect of planting density of the macrophyte consortium of Typha domingensis and Eleocharis acutangula on phytoremediation of barium from a flooded contaminated soil

    Viana, Douglas Gomes / Pires, Fábio Ribeiro / Ferreira, Amanda Duim / Egreja Filho, Fernando Barboza / Carvalho, Cássio Francisco Moreira de / Bonomo, Robson / Martins, Luiz Fernando

    Chemosphere. 2021 Jan., v. 262

    2021  

    Abstract: Barite (BaSO₄) is a component of drilling fluids used in the oil and gas industry and may cause barium (Ba) contamination if it is spilled onto flooded soils. Under anoxic soil conditions and low redox potential, sulfate can be reduced to a more soluble ... ...

    Abstract Barite (BaSO₄) is a component of drilling fluids used in the oil and gas industry and may cause barium (Ba) contamination if it is spilled onto flooded soils. Under anoxic soil conditions and low redox potential, sulfate can be reduced to a more soluble form (sulfide), and Ba can be made available. To design a solution for such environmental issues, a field study was conducted in a Ba-contaminated flooded area in Brazil, in which we induced Ba phytoextraction from the management of the planting density of two intercropped macrophytes. Typha domingensis and Eleocharis acutangula were grown in four initial planting densities: “Ld” (low density: 4 and 32 plants m⁻²); “Md” (medium density: 8 and 64 plants m⁻²); “Hd” (high density: 12 and 128 plants m⁻²); “Vhd” (very high density: 16 and 256 plants m⁻²). Vhd produced the largest number of plants after 300 days. However, the treatments did not differ in terms of the amount of biomass. The increments in the initial planting density did not increase the Ba concentration in the aerial part. The greatest Ba phytoextraction (aerial part + root) was achieved by Ld treatment, which removed approximately 3 kg of Ba ha⁻¹. Md and Vhd treatments had the highest Ba translocation factors. Because more plants per area did not result in greater Ba phytoextraction, a lower planting density was recommended for the intercropping of T. domingensis and E. acutangula to promote the phytoextraction of barium, due to possible lower implementation costs in contaminated flooded environments.
    Keywords Eleocharis ; Typha domingensis ; aerial parts ; barite ; barium ; biomass ; intercropping ; macrophytes ; oil and gas industry ; phytoaccumulation ; polluted soils ; redox potential ; sulfides ; Brazil
    Language English
    Dates of publication 2021-01
    Publishing place Elsevier Ltd
    Document type Article
    Note NAL-light
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2020.127869
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  8. Article ; Online: Synthesis, Assessment of Antineoplastic Activity, and Molecular Docking of Novel 2-Thioxo-oxazolidin-4-one Derivatives.

    Ramalho, Eduardo Augusto Vasconcelos de Freitas / Viana, Douglas Carvalho Francisco / Mendonça da Costa, Valécia de Cassia / Pitta, Maira / Rêgo, Moacyr Jesus Barreto de Melo / Pitta, Ivan da Rocha / Pitta, Marina Galdino da Rocha

    Medicinal chemistry (Shariqah (United Arab Emirates))

    2022  Volume 18, Issue 9, Page(s) 980–989

    Abstract: Background: Oxazolidinones display several biological effects, including anticancer activity. The purpose of this present work was to investigate a series of novel oxazolidinone derivatives with potential antineoplastic activity. Their mechanisms of ... ...

    Abstract Background: Oxazolidinones display several biological effects, including anticancer activity. The purpose of this present work was to investigate a series of novel oxazolidinone derivatives with potential antineoplastic activity. Their mechanisms of death induction and effects in the cell cycle were also evaluated. A molecular docking study was accomplished through proteins of the Cyclin-Dependent Kinases family (CDK). The new compound LPSF/NBM-2 was appeared to promote cell cycle arrest at the G2/M phase and increase the percentage of apoptotic cells.
    Methods: Oxazolidinone derivatives were obtained through Knoevenagel condensation. The cytotoxic assay was evaluated through the MTT method. Moreover, flow cytometry was performed in order to investigate the effects of the new compounds on the cell cycle, induction of cell death, and apoptosis. A blind docking was performed through the SwissDock online server and the analysis of the results was performed using the UCSF Chimera and Biovia discovery studio software.
    Results: LPSF/NBM-1 and LPSF/NBM-2 displayed the most cytotoxic activity against HL-60 (IC50 = 54.83 μM) and MOLT-4 (IC50 = 51.61 μM) cell lines. LPSF/NBM-2 showed an increased percentage of cell population at the G2/M phase. Molecular-docking results of LPSF/NBM-1 and LPSF/NBM-2 suggested a binding affinity with the evaluated CDK proteins.
    Conclusion: LPSF/NBM-1 and LPSF/NBM-2 displayed cytotoxic profiles against Hl-60 and MOLT-4. LPSF/NBM-2 increased cell population percentage at the G2/M phase and promoted cell death compared to non-treated cells in the MOLT-4 cell line. Based on these findings, oxazolidinone derivatives could be highlighted as possible cytostatic agents against lymphoma cells. Molecular docking results suggested the action of LPSF/NBM-1 and LPSF/NBM-2 compounds on enzymes of cyclin-dependent kinases family, however, more studies are needed to establish this correlation.
    MeSH term(s) Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Humans ; Molecular Docking Simulation ; Molecular Structure ; Oxindoles ; Structure-Activity Relationship
    Chemical Substances Antineoplastic Agents ; Oxindoles
    Language English
    Publishing date 2022-03-05
    Publishing country Netherlands
    Document type Journal Article
    ISSN 1875-6638
    ISSN (online) 1875-6638
    DOI 10.2174/1573406418666220304221557
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  9. Article ; Online: Effect of planting density of the macrophyte consortium of Typha domingensis and Eleocharis acutangula on phytoremediation of barium from a flooded contaminated soil.

    Viana, Douglas Gomes / Pires, Fábio Ribeiro / Ferreira, Amanda Duim / Egreja Filho, Fernando Barboza / Carvalho, Cássio Francisco Moreira de / Bonomo, Robson / Martins, Luiz Fernando

    Chemosphere

    2020  Volume 262, Page(s) 127869

    Abstract: ... Barite ( ... ...

    Abstract Barite (BaSO
    MeSH term(s) Barium ; Barium Sulfate ; Biodegradation, Environmental ; Biomass ; Brazil ; Eleocharis ; Floods ; Soil ; Soil Pollutants/analysis ; Soil Pollutants/metabolism ; Typhaceae/physiology
    Chemical Substances Soil ; Soil Pollutants ; Barium (24GP945V5T) ; Barium Sulfate (25BB7EKE2E)
    Language English
    Publishing date 2020-08-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2020.127869
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  10. Article: Chemical attributes of sewage sludges: Relationships to sources and treatments, and implications for sludge usage in agriculture

    Nascimento, Altina Lacerda / de Souza, Adijailton José / Oliveira, Fernando Carvalho / Coscione, Aline Renée / Viana, Douglas Gomes / Regitano, Jussara Borges

    Journal of cleaner production. 2020 June 10, v. 258

    2020  

    Abstract: São Paulo is the most populous and industrialized state of Brazil, which strongly affect amounts and composition of the generated sewage sludges. Their use on agriculture sounds the most feasible disposal strategy since most Brazilian soils have low ... ...

    Abstract São Paulo is the most populous and industrialized state of Brazil, which strongly affect amounts and composition of the generated sewage sludges. Their use on agriculture sounds the most feasible disposal strategy since most Brazilian soils have low fertility, but the levels of hazardous substances must be low. This research examined the impacts of sewage source [domestic or mixed (domestic + industrial)] and sewage processing (liming and redox conditions) on the chemical attributes of sludges from 19 wastewater treatment plants of São Paulo; as well as their suitability for agricultural use. Sewage source and liming were the main factors affecting sludges’ chemical attributes, while redox conditions played a secondary role. Aerobically treated domestic sewage (C1) generated sludges most suitable for agriculture. Heavy liming in the processing of sewage of mixed origin (C2) produced sludges of much higher pH and Ca, with higher levels of certain hazardous elements (Fe, Zn, Mn, and Cr), but lower levels of OC, N-Kj, and K. Sludges from mixed sewers, not limed (C3) tended to have higher levels of S and hazardous elements (Ba, Mo, Cd, Pb, Ni, Al, and Cu). The inadequately regulated discharge of industrial wastewater into the municipal sewage network accounted for higher levels of hazardous elements in the sludges, but all of them are still suitable for agricultural use since only four sludges showed levels of either Zn (3) or Ni (1) that exceeded the thresholds permitted for direct application to agricultural fields, but both are nutrients to plants and Brazilian soils are often depleted on them. As raw materials for the manufacture of organic fertilizers, the levels of Cd, Cr, or Ni were unacceptable in about half (9) of the samples. It should be revised since hazardous element contents are diluted in the manufacture of the “new compound” and their application rates should be much lower than when sludge is directly applied. In conclusion, “low quality” sludges, such as C2 and mainly C3, have to be either composted or biodigested into “high quality” stabilized sludges; or used in the manufacture of organomineral fertilizers; or treated to remove pathogens and hazardous substances to be amended to agricultural soils, thus avoiding their non-sustainable disposal in landfills.
    Keywords agricultural land ; agricultural soils ; aluminum ; application rate ; barium ; cadmium ; calcium ; chromium ; copper ; industrial wastewater ; industrialization ; iron ; landfills ; lead ; liming ; manganese ; manufacturing ; molybdenum ; nickel ; nutrients ; organic fertilizers ; pH ; pathogens ; raw materials ; sewage ; sewer systems ; sludge ; toxic substances ; wastewater treatment ; zinc ; Brazil
    Language English
    Dates of publication 2020-0610
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 0959-6526
    DOI 10.1016/j.jclepro.2020.120746
    Database NAL-Catalogue (AGRICOLA)

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