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  1. AU="Vicente, Agustín"
  2. AU="Thampi, Swapna"
  3. AU="Jaimes, Javier A."
  4. AU="Ennio?Ferrari"
  5. AU="Cane, Douglas"
  6. AU="Vasiliauskaite, Lina"
  7. AU="Fraczek, Paula M"
  8. AU="Fritz, Cassandra Dl"
  9. AU="Sommer, Norbert"
  10. AU="Brandão, Claudia Valeria S"
  11. AU="Jesky, Mark D"
  12. AU="Filipe de Oliveira"
  13. AU="Chang, Shantel"
  14. AU="Mbow, M Lamine"
  15. AU="Sekhon, M."
  16. AU="Song, Y-S"
  17. AU="Collins, Brooke"
  18. AU="Ali Al-Naji"
  19. AU="Bansal, Bhavtosh"
  20. AU="De Cremer, Kaat"
  21. AU="O'Neil, James"
  22. AU=White Tonya
  23. AU="Clark-Deener, Sherrie"
  24. AU="Ishak Yassir"
  25. AU="Chih-Wei Chen"

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  1. Artikel: What does it take to be rigid? Reflections on the notion of rigidity in autism.

    Petrolini, Valentina / Jorba, Marta / Vicente, Agustín

    Frontiers in psychiatry

    2023  Band 14, Seite(n) 1072362

    Abstract: Characterizations of autism include multiple references to rigid or inflexible features, but the notion of rigidity itself has received little systematic discussion. In this paper we shed some light on the notion of rigidity in autism by identifying ... ...

    Abstract Characterizations of autism include multiple references to rigid or inflexible features, but the notion of rigidity itself has received little systematic discussion. In this paper we shed some light on the notion of rigidity in autism by identifying different facets of this phenomenon as discussed in the literature, such as fixed interests, insistence on sameness, inflexible adherence to routines, black-and-white mentality, intolerance of uncertainty, ritualized patterns of verbal and non-verbal behavior, literalism, and discomfort with change. Rigidity is typically approached in a disjointed fashion (i.e., facet by facet), although there are recent attempts at providing unifying explanations. Some of these attempts assume that the rigidity facets mainly relate to executive functioning: although such an approach is intuitively persuasive, we argue that there are equally plausible alternative explanations. We conclude by calling for more research on the different facets of rigidity and on how they cluster together in the autistic population, while suggesting some ways in which intervention could benefit from a finer-grained view of rigidity.
    Sprache Englisch
    Erscheinungsdatum 2023-02-13
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1072362
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  2. Artikel ; Online: Linguistic, concept and symbolic composition in adults with minimal receptive vocabulary.

    Vicente, Agustín / Barbarroja, Natàlia / Castroviejo, Elena

    Clinical linguistics & phonetics

    2023  Band 38, Heft 2, Seite(n) 155–171

    Abstract: In this paper, we examine some basic linguistic abilities in a small sample of adults with minimal receptive vocabulary, whose receptive mental verbal age ranges from 1;2 to 3;10. In particular, we examine whether the participants in our study understand ...

    Abstract In this paper, we examine some basic linguistic abilities in a small sample of adults with minimal receptive vocabulary, whose receptive mental verbal age ranges from 1;2 to 3;10. In particular, we examine whether the participants in our study understand noun phrases consisting of a noun modified by an adjective. We use stimuli that they can recognise by name. Except for one participant, we find that, while all of them understand the noun and adjective in isolation, none seems to understand these noun phrases, which means that they seem to not do linguistic composition. In order to test whether the difficulty is linguistic or conceptual, we ran two other studies, one on concept composition, and the other on iconic symbolic composition (composition of pictograms). Results suggest that linguistic composition is particularly difficult in this population, and that vocabulary breadth may not predict compositional abilities.
    Mesh-Begriff(e) Adult ; Humans ; Vocabulary ; Linguistics
    Sprache Englisch
    Erscheinungsdatum 2023-03-02
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639459-0
    ISSN 1464-5076 ; 0269-9206
    ISSN (online) 1464-5076
    ISSN 0269-9206
    DOI 10.1080/02699206.2023.2180670
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  3. Artikel ; Online: Las prácticas electorales coloniales y la conformación de un habitus electoral. El Cabildo de la Villa de Luján entre 1771 y 1821

    Vicente Agustín Galimberti

    Prohistoria, Iss

    2018  Band 29

    Abstract: Este artículo examina los procesos electorales desarrollados durante las últimas décadas del período colonial en la jurisdicción del Cabildo de la Villa de Luján. El objetivo del mismo consiste en analizar la posible existencia de tradiciones y prácticas ...

    Abstract Este artículo examina los procesos electorales desarrollados durante las últimas décadas del período colonial en la jurisdicción del Cabildo de la Villa de Luján. El objetivo del mismo consiste en analizar la posible existencia de tradiciones y prácticas electorales coloniales que pudieron haber informado y orientado a los actores frente a los cambios que trajo en las elecciones la adopción del principio de la soberanía popular durante de la revolución. Analizamos la vida política local, considerando a los habitantes y los pueblos rurales como sujetos activos en la construcción tanto de una tradición electoral como en los cambios que se desarrollaron en ella durante las primeras décadas del siglo XIX.
    Schlagwörter elecciones ; política local ; peticiones ; soberanía popular ; campaña de Buenos Aires ; History (General) and history of Europe ; D ; History (General) ; D1-2009
    Sprache Spanisch
    Erscheinungsdatum 2018-06-01T00:00:00Z
    Verlag Grupo Prohistoria
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Las prácticas electorales coloniales y la conformación de un habitus electoral. El Cabildo de la Villa de Luján entre 1771 y 1821

    Vicente Agustín Galimberti

    Prohistoria, Iss

    2018  Band 29

    Abstract: Este artículo examina los procesos electorales desarrollados durante las últimas décadas del período colonial en la jurisdicción del Cabildo de la Villa de Luján. El objetivo del mismo consiste en analizar la posible existencia de tradiciones y prácticas ...

    Abstract Este artículo examina los procesos electorales desarrollados durante las últimas décadas del período colonial en la jurisdicción del Cabildo de la Villa de Luján. El objetivo del mismo consiste en analizar la posible existencia de tradiciones y prácticas electorales coloniales que pudieron haber informado y orientado a los actores frente a los cambios que trajo en las elecciones la adopción del principio de la soberanía popular durante de la revolución. Analizamos la vida política local, considerando a los habitantes y los pueblos rurales como sujetos activos en la construcción tanto de una tradición electoral como en los cambios que se desarrollaron en ella durante las primeras décadas del siglo XIX.
    Schlagwörter Elecciones ; Política local ; Peticiones ; Soberanía popular ; Campaña de Buenos Aires ; History (General) and history of Europe ; D ; History (General) ; D1-2009
    Sprache Spanisch
    Erscheinungsdatum 2018-06-01T00:00:00Z
    Verlag Grupo Prohistoria
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel ; Online: Profiling Cell Heterogeneity and Fructose Transporter Expression in the Rat Nephron by Integrating Single-Cell and Microdissected Tubule Segment Transcriptomes.

    Zhang, Ronghao / Jadhav, Darshan Aatmaram / Kim, Najeong / Kramer, Benjamin / Gonzalez-Vicente, Agustin

    International journal of molecular sciences

    2024  Band 25, Heft 5

    Abstract: Single-cell RNA sequencing (scRNAseq) is a crucial tool in kidney research. These technologies cluster cells based on transcriptome similarity, irrespective of the anatomical location and order within the nephron. Thus, a transcriptome cluster may ... ...

    Abstract Single-cell RNA sequencing (scRNAseq) is a crucial tool in kidney research. These technologies cluster cells based on transcriptome similarity, irrespective of the anatomical location and order within the nephron. Thus, a transcriptome cluster may obscure the heterogeneity of the cell population within a nephron segment. Elevated dietary fructose leads to salt-sensitive hypertension, in part, through fructose reabsorption in the proximal tubule (PT). However, the organization of the four known fructose transporters in apical PTs (SGLT4, SGLT5, GLUT5, and NaGLT1) remains poorly understood. We hypothesized that cells within each subsegment of the proximal tubule exhibit complex, heterogeneous fructose transporter expression patterns. To test this hypothesis, we analyzed rat kidney transcriptomes and proteomes from publicly available scRNAseq and tubule microdissection databases. We found that microdissected PT-S1 segments consist of 81% ± 12% cells with scRNAseq-derived transcriptional characteristics of S1, whereas PT-S2 express a mixture of 18% ± 9% S1, 58% ± 8% S2, and 19% ± 5% S3 transcripts, and PT-S3 consists of 75% ± 9% S3 transcripts. The expression of all four fructose transporters was detectable in all three PT segments, but key fructose transporters SGLT5 and GLUT5 progressively increased from S1 to S3, and both were significantly upregulated in S3 vs. S1/S2 (
    Mesh-Begriff(e) Humans ; Rats ; Animals ; Transcriptome ; Fructose/metabolism ; Nephrons/metabolism ; Kidney/metabolism ; Kidney Tubules, Proximal/metabolism ; Membrane Transport Proteins/metabolism
    Chemische Substanzen Fructose (30237-26-4) ; Membrane Transport Proteins
    Sprache Englisch
    Erscheinungsdatum 2024-03-06
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25053071
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  6. Artikel ; Online: Knocking Out Sodium Glucose-Linked Transporter 5 Prevents Fructose-Induced Renal Oxidative Stress and Salt-Sensitive Hypertension.

    Forester, Beau R / Zhang, Ronghao / Schuhler, Brett / Brostek, Autumn / Gonzalez-Vicente, Agustin / Garvin, Jeffrey L

    Hypertension (Dallas, Tex. : 1979)

    2024  Band 81, Heft 6, Seite(n) 1296–1307

    Abstract: Background: A fructose high-salt (FHS) diet increases systolic blood pressure and Ang II (angiotensin II)-stimulated proximal tubule (PT) superoxide (O: Methods: We measured systolic blood pressure in male and female Sprague-Dawley (wild type [WT]), ... ...

    Abstract Background: A fructose high-salt (FHS) diet increases systolic blood pressure and Ang II (angiotensin II)-stimulated proximal tubule (PT) superoxide (O
    Methods: We measured systolic blood pressure in male and female Sprague-Dawley (wild type [WT]), SGLT4 knockout (
    Results: In male WT and female WT rats, FHS increased systolic blood pressure by 15±3 (n=7;
    Conclusions: SGLT5-mediated PT fructose reabsorption is required for FHS to augment Ang II-stimulated proximal nephron O
    Mesh-Begriff(e) Animals ; Fructose/pharmacology ; Oxidative Stress/drug effects ; Male ; Female ; Rats ; Hypertension/metabolism ; Hypertension/genetics ; Hypertension/chemically induced ; Hypertension/physiopathology ; Rats, Sprague-Dawley ; Blood Pressure/drug effects ; Blood Pressure/physiology ; Kidney Tubules, Proximal/metabolism ; Kidney Tubules, Proximal/drug effects ; Sodium-Glucose Transport Proteins/genetics ; Sodium-Glucose Transport Proteins/metabolism ; Sodium Chloride, Dietary/adverse effects ; Angiotensin II ; Disease Models, Animal
    Sprache Englisch
    Erscheinungsdatum 2024-03-28
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.123.22535
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  7. Artikel: Profiling cellular heterogeneity and fructose transporter expression in the rat nephron by integrating single-cell and microdissected tubule segment transcriptomes.

    Zhang, Ronghao / Jadhav, Darshan Aatmaram / Kramer, Benjamin / Gonzalez-Vicente, Agustin

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Single-cell RNA sequencing (scRNAseq) is a crucial tool in kidney research. These technologies cluster cells according to transcriptome similarity, irrespective of the anatomical location and ordering within the nephron. Thus, a cluster transcriptome may ...

    Abstract Single-cell RNA sequencing (scRNAseq) is a crucial tool in kidney research. These technologies cluster cells according to transcriptome similarity, irrespective of the anatomical location and ordering within the nephron. Thus, a cluster transcriptome may obscure heterogeneity of the cell population within a nephron segment. Elevated dietary fructose leads to salt-sensitive hypertension, in part by fructose reabsorption in the proximal tubule (PT). However, organization of the four known fructose transporters in apical PTs (SGLT4, SGLT5, GLUT5 and NaGLT1) remains poorly understood. We hypothesized that cells within each subsegment of the proximal tubule exhibit complex, heterogenous fructose transporter expression patterns. To test this hypothesis we analyzed rat and kidney transcriptomes and proteomes from publicly available scRNAseq and tubule microdissection databases. We found that microdissected PT-S1 segments consist of 81±12% cells with scRNAseq-derived transcriptional characteristics of S1, whereas PT-S2 express a mixture of 18±9% S1, 58±8% S2, and 19±5% S3 transcripts, and PT-S3 consists of 75±9% S3 transcripts. The expression of all four fructose transporters was detectable in all three PT segments, but key fructose transporters SGLT5 and GLUT5 progressively increased from S1 to S3, and both were significantly upregulated in S3 vs. S1/S2 (Slc5a10: 1.9 log
    Sprache Englisch
    Erscheinungsdatum 2023-12-22
    Erscheinungsland United States
    Dokumenttyp Preprint
    DOI 10.1101/2023.12.20.572656
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  8. Artikel ; Online: La pandemia de “influenza española” en el municipio de Aguascalientes, 1918

    María Guadalupe Rodríguez López / Vicente Agustín Esparza Jiménez

    Oficio, Revista de Historia e Interdisciplina, Pp 65-

    2020  Band 88

    Abstract: Este artículo analiza la presencia de la pandemia de "influenza española" en el municipio de Aguascalientes a través de las actas de defunción correspondientes al año de 1918 y las acciones emprendidas por el gobierno municipal para hacer frente a dicha ... ...

    Abstract Este artículo analiza la presencia de la pandemia de "influenza española" en el municipio de Aguascalientes a través de las actas de defunción correspondientes al año de 1918 y las acciones emprendidas por el gobierno municipal para hacer frente a dicha enfermedad. En un primer momento se abordan los antecedentes generales de la influenza a finales del siglo XIX en Aguascalientes, para después estudiar las principales características de la "influenza española" y, finalmente, la presencia de la epidemia en el municipio de Aguascalientes, para conocer cómo fue su desarrollo y cuáles fueron las medidas tomadas por parte de las autoridades para evitar su transmisión.
    Schlagwörter pandemia ; higiene ; aguascalientes ; History of scholarship and learning. The humanities ; AZ20-999 ; History (General) and history of Europe ; D ; Latin America. Spanish America ; F1201-3799
    Sprache Englisch
    Erscheinungsdatum 2020-12-01T00:00:00Z
    Verlag Departamento de Historia, Universidad de Guanajuato
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel ; Online: Angiotensin II-stimulated proximal nephron superoxide production and fructose-induced salt-sensitive hypertension.

    Forester, Beau R / Brostek, Autumn / Schuhler, Brett / Gonzalez-Vicente, Agustin / Garvin, Jeffrey L

    American journal of physiology. Renal physiology

    2023  Band 326, Heft 2, Seite(n) F249–F256

    Abstract: Angiotensin II (ANG II) increases proximal tubule superoxide ( ... ...

    Abstract Angiotensin II (ANG II) increases proximal tubule superoxide (O
    Mesh-Begriff(e) Humans ; Rats ; Male ; Animals ; Rats, Sprague-Dawley ; Angiotensin II/pharmacology ; Angiotensin II/metabolism ; Superoxides/metabolism ; Losartan/pharmacology ; Fructose/pharmacology ; Hypertension/chemically induced ; Hypertension/metabolism ; Sodium Chloride/metabolism ; Nephrons/metabolism ; Sodium Chloride, Dietary/metabolism ; Blood Pressure ; Protein Kinase C/metabolism ; Glucose/pharmacology ; Cyclic N-Oxides ; Spin Labels
    Chemische Substanzen tempol (U78ZX2F65X) ; Angiotensin II (11128-99-7) ; Superoxides (11062-77-4) ; Losartan (JMS50MPO89) ; Fructose (30237-26-4) ; Sodium Chloride (451W47IQ8X) ; Sodium Chloride, Dietary ; Protein Kinase C (EC 2.7.11.13) ; Glucose (IY9XDZ35W2) ; Cyclic N-Oxides ; Spin Labels
    Sprache Englisch
    Erscheinungsdatum 2023-12-07
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 603837-2
    ISSN 1522-1466 ; 0363-6127
    ISSN (online) 1522-1466
    ISSN 0363-6127
    DOI 10.1152/ajprenal.00289.2023
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  10. Artikel ; Online: A novel image database for social concepts reveals preference biases in autistic spectrum in adults and children.

    Soto, David / Salazar, Amaia / Elosegi, Patxi / Walter, Antje / Mei, Ning / Rodriguez, Ekaine / Petrollini, Valentina / Vicente, Agustín

    Psychonomic bulletin & review

    2024  

    Abstract: Human beings display the extraordinary ability of grasping and communicating abstract concepts. Yet, no standardized instruments exist to assess this ability. Developing these tools is paramount for understanding abstract representations such as social ... ...

    Abstract Human beings display the extraordinary ability of grasping and communicating abstract concepts. Yet, no standardized instruments exist to assess this ability. Developing these tools is paramount for understanding abstract representations such as social concepts, with ramifications in educational and clinical settings. Here, we developed an image database depicting abstract social concepts varying in social desirability. We first validated the image database in a sample of neurotypical participants. Then, we applied the database to test different hypotheses regarding how social concepts are represented across samples of adults and children with autism spectrum condition (ASC). Relative to the neurotypicals, we did not observe differences related to ASC in identification performance of the social desirability of the concepts, nor differences in metacognitive ability. However, we observed a preference bias away from prosocial concepts that was linked to individual autistic traits in the neurotypicals, and higher in ASC relative to the neurotypicals both in adults and children. These results indicate that abstract representations such as social concepts are dependent on individual neurodevelopmental traits. The image database thus provides a standardized assessment tool for investigating the representation of abstract social concepts in the fields of psycholinguistics, neuropsychology, neuropsychiatry, and cognitive neuroscience, across different cultures and languages.
    Sprache Englisch
    Erscheinungsdatum 2024-01-18
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2031311-1
    ISSN 1531-5320 ; 1069-9384
    ISSN (online) 1531-5320
    ISSN 1069-9384
    DOI 10.3758/s13423-023-02443-7
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