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  1. Article ; Online: A Scientometric Analysis of Africa's Health Science Journals Indexed in International and Regional Databases: A Comparative Analysis.

    Selemani, Apatsa / Wella, Kondwani / Chen, Yen-Fu / Vicente-Crespo, Marta / Uthman, Olalekan / Igumbor, Jude

    International journal of public health

    2024  Volume 68, Page(s) 1606415

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) Humans ; Periodicals as Topic ; Bibliometrics ; Journal Impact Factor ; Databases, Factual ; Africa
    Language English
    Publishing date 2024-01-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2274130-6
    ISSN 1661-8564 ; 1661-8556
    ISSN (online) 1661-8564
    ISSN 1661-8556
    DOI 10.3389/ijph.2023.1606415
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 843: Show issues Location:
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  2. Article ; Online: Transformed through the CARTA experience: changes reported by CARTA fellows about their PhD journey.

    Ruhweza Katahoire, Anne / Allison, Jill / Vicente-Crespo, Marta / Fonn, Sharon

    Global health action

    2023  Volume 16, Issue 1, Page(s) 2272392

    Abstract: Transformative learning occurs when a person, group, or larger social unit encounters ideas that are at odds with their prevailing perspective. This discrepant perspective can lead to an examination of previously held beliefs, values, and assumptions. ... ...

    Abstract Transformative learning occurs when a person, group, or larger social unit encounters ideas that are at odds with their prevailing perspective. This discrepant perspective can lead to an examination of previously held beliefs, values, and assumptions. The Consortium for Advanced Research Training in Africa (CARTA) has since 2011 been training and supporting faculty from different African universities, to become more reflective and productive researchers, research leaders, educators, and change agents who will drive institutional changes in their institutions. As part of a mid-term evaluation of CARTA, an open-ended question was posed to the CARTA fellows asking them to describe any changes they had experienced in their professional lives as a result of the CARTA Programme. The 135 responses were inductively coded and analysed using qualitative thematic analysis. These themes were subsequently mapped onto Hoggan's typology of transformative learning outcomes. CARTA fellows reported shifts in their sense of self; worldviews; beliefs about the definition of knowledge, how it is constructed and evaluated; and changes in behaviour/practices and capacities. This paper argues that the changes described by the CARTA fellows reflect transformative learning that is embedded in CARTA's Theory of Change. The reported transformation was enabled by a curriculum intentionally designed to facilitate critical reflection, further exploration, and questioning, both formally and informally during the fellows' PhD journey with the support of CARTA facilitators. Documenting and disseminating these lessons provide a guide for future practice, and educators wishing to revitalise their PhD training may find it useful to review the CARTA PhD curriculum.
    MeSH term(s) Humans ; Africa ; Curriculum ; Learning ; Faculty ; Research Personnel/education
    Language English
    Publishing date 2023-11-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2540569-X
    ISSN 1654-9880 ; 1654-9880
    ISSN (online) 1654-9880
    ISSN 1654-9880
    DOI 10.1080/16549716.2023.2272392
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Resilience of research capacity strengthening initiatives in Africa during crises: the case of CARTA during COVID.

    Karimi, Florah / Vicente-Crespo, Marta / Ndwiga, Mercy / Njenga, Naomi / Karoki, Rita / Fonn, Sharon

    Global health action

    2023  Volume 16, Issue 1, Page(s) 2240153

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Humans ; COVID-19/epidemiology ; Africa ; Interdisciplinary Studies ; Pandemics/prevention & control
    Language English
    Publishing date 2023-08-16
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2540569-X
    ISSN 1654-9880 ; 1654-9880
    ISSN (online) 1654-9880
    ISSN 1654-9880
    DOI 10.1080/16549716.2023.2240153
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Attenuation of Seizures, Cognitive Deficits, and Brain Histopathology by Phytochemicals of

    Ssempijja, Fred / Dare, Samuel Sunday / Bukenya, Edmund E M / Kasozi, Keneth Iceland / Kenganzi, Ritah / Fernandez, Edgar Mario / Vicente-Crespo, Marta

    Journal of evidence-based integrative medicine

    2023  Volume 28, Page(s) 2515690X231160191

    Abstract: ... Imperata ... ...

    Abstract Imperata cylindrica
    MeSH term(s) Animals ; Drosophila melanogaster ; Poaceae ; Anticonvulsants/pharmacology ; Brain ; Seizures/drug therapy ; Seizures/genetics ; Epilepsy/drug therapy ; Epilepsy/genetics ; Drosophila ; Cognition ; Phytochemicals/pharmacology ; Plant Extracts/pharmacology
    Chemical Substances Anticonvulsants ; Phytochemicals ; Plant Extracts
    Language English
    Publishing date 2023-03-08
    Publishing country United States
    Document type Journal Article
    ISSN 2515-690X
    ISSN (online) 2515-690X
    DOI 10.1177/2515690X231160191
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Institutionalizing research capacity strengthening in LMICs: A systematic review and meta-synthesis.

    Vicente-Crespo, Marta / Agunbiade, Ojo / Eyers, John / Thorogood, Margaret / Fonn, Sharon

    AAS open research

    2021  Volume 3, Page(s) 43

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2021-02-12
    Publishing country England
    Document type Systematic Review
    ISSN 2515-9321
    ISSN (online) 2515-9321
    DOI 10.12688/aasopenres.13116.3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Competencies for Transformational Leadership in Public Health-An International Delphi Consensus Study.

    Bürkin, Barbara Maria / Czabanowska, Katarzyna / Babich, Suzanne / Casamitjana, Núria / Vicente-Crespo, Marta / De Souza, Luis Eugenio / Ehrenberg, John P / Hoffmann, Axel / Kamath, Rajesh / Matthiä, Anja / Okumu, Fredros / Rutebemberwa, Elizeus / Waser, Marco / Kuenzli, Nino / Bohlius, Julia

    International journal of public health

    2024  Volume 69, Page(s) 1606267

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) Humans ; Clinical Competence ; Curriculum ; Delphi Technique ; Leadership ; Professional Competence ; Public Health
    Language English
    Publishing date 2024-02-23
    Publishing country Switzerland
    Document type Consensus Development Conference ; Journal Article
    ZDB-ID 2274130-6
    ISSN 1661-8564 ; 1661-8556
    ISSN (online) 1661-8564
    ISSN 1661-8556
    DOI 10.3389/ijph.2024.1606267
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 843: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Resveratrol prolongs lifespan and improves 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced oxidative damage and behavioural deficits in Drosophila melanogaster.

    Abolaji, Amos O / Adedara, Adeola O / Adie, Mojisola A / Vicente-Crespo, Marta / Farombi, Ebenezer O

    Biochemical and biophysical research communications

    2018  Volume 503, Issue 2, Page(s) 1042–1048

    Abstract: 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) is a neurotoxin that causes Parkinson's disease in animals via mechanisms linked with oxidative stress and inflammation. Resveratrol is a natural polyphenol and a phytoalexin with antioxidative and ... ...

    Abstract 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) is a neurotoxin that causes Parkinson's disease in animals via mechanisms linked with oxidative stress and inflammation. Resveratrol is a natural polyphenol and a phytoalexin with antioxidative and antiinflammatory properties. Here, we investigated the rescue role of resveratrol on MPTP-triggered toxicity in Drosophila melanogaster for the first time. D. melanogaster (Harwich strain, 1-to 3- days old) were first orally exposed to resveratrol (0, 7.5, 15, 30, 60 and 120 mg/kg diet) and MPTP (0, 250, 500, 1000, 2000, and 3000 μM) for longevity and 7 days survival assays respectively. Consequently, we selected resveratrol (30 and 60 mg/kg diet) to evaluate its rescue role on MPTP (250 and 500 μM)-induced toxicity in D. melanogaster after 3 days of oral treatment. Specifically, we evaluated markers of neurotoxicity (acetylcholinesterase and negative geotaxis), inflammation (nitric oxide), oxidative stress-antioxidant status (hydrogen peroxide, total thiol, catalase and glutathione-S-transferase), cell viability and fecundity. The data showed that resveratrol increased lifespan of D. melanogaster in a dose-dependent manner up to 60 mg/kg diet. Further, resveratrol restored MPTP-induced inhibition of catalase, glutathione-S-transferase and acetylcholinesterase activities in D. melanogaster. Moreover, resveratrol ameliorated MPTP-triggered cell death, histological alterations, behavioural deficits and accumulation of nitric oxide and hydrogen peroxide levels in flies (p < 0.05). Conclusively, the lifespan extension effects of resveratrol and its rescue role on MPTP- mediated toxicity in the flies may be due to its antioxidant and anti-inflammatory properties.
    MeSH term(s) 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/adverse effects ; Acetylcholinesterase/metabolism ; Animals ; Antioxidants/pharmacology ; Behavior, Animal/drug effects ; Catalase/metabolism ; Cell Survival/drug effects ; Drosophila melanogaster/drug effects ; Drosophila melanogaster/physiology ; Glutathione Transferase/metabolism ; Hydrogen Peroxide/metabolism ; Longevity/drug effects ; Nitric Oxide/metabolism ; Oxidative Stress/drug effects ; Parkinson Disease, Secondary/chemically induced ; Parkinson Disease, Secondary/metabolism ; Resveratrol/pharmacology
    Chemical Substances Antioxidants ; Nitric Oxide (31C4KY9ESH) ; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (9P21XSP91P) ; Hydrogen Peroxide (BBX060AN9V) ; Catalase (EC 1.11.1.6) ; Glutathione Transferase (EC 2.5.1.18) ; Acetylcholinesterase (EC 3.1.1.7) ; Resveratrol (Q369O8926L)
    Language English
    Publishing date 2018-06-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2018.06.114
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 116: Show issues Location:
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  8. Article: Considerations for an integrated population health databank in Africa: lessons from global best practices.

    Igumbor, Jude O / Bosire, Edna N / Vicente-Crespo, Marta / Igumbor, Ehimario U / Olalekan, Uthman A / Chirwa, Tobias F / Kinyanjui, Sam M / Kyobutungi, Catherine / Fonn, Sharon

    Wellcome open research

    2021  Volume 6, Page(s) 214

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-08-23
    Publishing country England
    Document type Journal Article
    ISSN 2398-502X
    ISSN 2398-502X
    DOI 10.12688/wellcomeopenres.17000.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Enhancing science preparedness for health emergencies in Africa through research capacity building.

    Kinyanjui, Sam / Fonn, Sharon / Kyobutungi, Catherine / Vicente-Crespo, Marta / Bonfoh, Bassirou / Ndungu, Thumbi / Sewankambo, Nelson Kaulukusi / Djimde, Abdoulaye A / Gaye, Oumar / Chirwa, Tobias / Musenge, Eustasius / Elliot, Alison / Nakanjako, Damalie / Chibanda, Dixon / Awandare, Gordon

    BMJ global health

    2020  Volume 5, Issue 7

    MeSH term(s) Africa ; Capacity Building ; Disaster Planning ; Emergencies ; Humans ; Public Health
    Keywords covid19
    Language English
    Publishing date 2020-07-07
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ISSN 2059-7908
    ISSN 2059-7908
    DOI 10.1136/bmjgh-2020-003072
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Nonsense-mediated mRNA decay and development: shoot the messenger to survive?

    Vicente-Crespo, Marta / Palacios, Isabel M

    Biochemical Society transactions

    2010  Volume 38, Issue 6, Page(s) 1500–1505

    Abstract: NMD (nonsense-mediated mRNA decay) is a surveillance mechanism that degrades transcripts containing nonsense mutations, preventing the translation of potentially harmful truncated proteins. Although the mechanistic details of NMD are gradually being ... ...

    Abstract NMD (nonsense-mediated mRNA decay) is a surveillance mechanism that degrades transcripts containing nonsense mutations, preventing the translation of potentially harmful truncated proteins. Although the mechanistic details of NMD are gradually being understood, the physiological role of this RNA surveillance pathway still remains largely unknown. The core NMD genes Upf1 (up-frameshift suppressor 1) and Upf2 are essential for animal viability in the fruitfly, mouse and zebrafish. These findings may reflect an important role for NMD during animal development. Alternatively, the lethal phenotypes of upf1 and upf2 mutants might be due to their function in NMD-independent processes. In the present paper, we describe the phenotypes observed when the NMD factors are mutated in various organisms, and discuss findings that might shed light on the function of NMD in cellular growth and development of an organism.
    MeSH term(s) Animals ; Codon, Nonsense ; Gene Knockdown Techniques ; Mice ; Phenotype ; RNA Stability/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
    Chemical Substances Codon, Nonsense ; RNA, Messenger
    Language English
    Publishing date 2010-12-23
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 184237-7
    ISSN 1470-8752 ; 0300-5127
    ISSN (online) 1470-8752
    ISSN 0300-5127
    DOI 10.1042/BST0381500
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 944: Show issues Location:
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