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  1. Article ; Online: Characteristics and Treatment of Gordonia spp. Bacteremia, France

    Alia Barthel / Axel Ursenbach / Charlotte Kaeuffer / Christelle Koebel / Alain Gravet / Dominique De Briel / Jacqueline Dubois / Elina Haerrel / Estelle Rougier / Victor Gerber

    Emerging Infectious Diseases, Vol 29, Iss 5, Pp 1025-

    2023  Volume 1028

    Abstract: Systemic Gordonia spp. infections are rare and occur mostly among immunocompromised patients. We analyzed 10 cases of Gordonia bacteremia diagnosed in 3 tertiary care centers in France to assess risk factors, treatment, and clinical outcomes. Most ... ...

    Abstract Systemic Gordonia spp. infections are rare and occur mostly among immunocompromised patients. We analyzed 10 cases of Gordonia bacteremia diagnosed in 3 tertiary care centers in France to assess risk factors, treatment, and clinical outcomes. Most patients were cured within 10 days by using β-lactam antimicrobial therapy and removing central catheters.
    Keywords Gordonia ; bacteremia ; bacteria ; Gram-positive ; nosocomial infections ; antimicrobial resistance ; Medicine ; R ; Infectious and parasitic diseases ; RC109-216
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher Centers for Disease Control and Prevention
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Detection of Pneumocystis jirovecii in Patients with Severe COVID-19

    Victor Gerber / Yvon Ruch / Thiên-Nga Chamaraux-Tran / Walid Oulehri / Francis Schneider / Veronique Lindner / Valentin Greigert / Julie Denis / Julie Brunet / François Danion

    Journal of Fungi, Vol 7, Iss 585, p

    Diagnostic and Therapeutic Challenges

    2021  Volume 585

    Abstract: Cases of Pneumocystis jirovecii pneumonia (PCP) in patients suffering from COVID-19 were described in patients with various comorbidities and outcomes. The diagnosis of PCP in these patients is difficult due to clinical and radiological similarities. We ... ...

    Abstract Cases of Pneumocystis jirovecii pneumonia (PCP) in patients suffering from COVID-19 were described in patients with various comorbidities and outcomes. The diagnosis of PCP in these patients is difficult due to clinical and radiological similarities. We carried out this study in order to better describe potentially at-risk patients and their outcomes. We retrospectively analyzed all patients with a P. jirovecii PCR performed in bronchoalveolar lavage fluid, tracheal aspirate, or sputum within a month after the COVID-19 diagnosis. Fifty-seven patients with COVID-19 infection were tested for P. jirovecii . Among 57 patients with COVID-19, four patients had a concomitant positive P. jirovecii PCR. These four patients were elderly with a mean age of 78. Two patients were immunocompromised, and the two others presented only diabetes mellitus. Three patients presented an ARDS requiring transfer to the ICU and mechanical ventilation. All patients presented lymphocytopenia. Three patients had probable PCP, and one had proven PCP. All patients died within two months after hospital admission. These co-infections are rare but severe, therefore, PCP should be considered in case of worsening of the condition of patients with severe COVID-19.
    Keywords pneumocystosis ; Pneumocystis jirovecii ; COVID-19 ; SARS-CoV-2 ; fungi ; Biology (General) ; QH301-705.5
    Subject code 610 ; 616
    Language English
    Publishing date 2021-07-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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