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  1. Article ; Online: Breast Cancer Screening Recommendations: African American Women Are at a Disadvantage.

    Rebner, Murray / Pai, Vidya R

    Journal of breast imaging

    2024  Volume 2, Issue 5, Page(s) 416–421

    Abstract: Since 1990, breast cancer mortality has decreased by 40% in white women but only 26% in African American women. The age at diagnosis of breast cancer is younger in black women. Breast cancer diagnosed before age 50 represents 23% of all breast cancers in ...

    Abstract Since 1990, breast cancer mortality has decreased by 40% in white women but only 26% in African American women. The age at diagnosis of breast cancer is younger in black women. Breast cancer diagnosed before age 50 represents 23% of all breast cancers in African American women but only 16% of all breast cancers in white women. White women have a higher incidence of breast cancer over the age of 60. Tumor subtypes also vary among racial and ethnic groups. The triple-negative (TN) subtype, which has a poorer outcome and occurs at a younger age, represents 21% of invasive breast cancers in black women but only 10% of invasive breast cancers in white women. The hormone receptor-positive subtype, which is more common in older women and has the best outcome, has a higher incidence in white women (70%) than in black women (61%). The BRCA2 mutation is also more common in black women than in white women (other than those who are of Ashkenazi Jewish ancestry). There are also many barriers to screening. Major ones include the lack of contact with a primary health care provider as well as a decreased perceived risk of having breast cancer in the African American population. Given the younger age of onset and the higher incidence of the TN molecular subtype, following breast cancer screening guidelines that do not support screening before the age of 50 may disadvantage black women.
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ISSN 2631-6129
    ISSN (online) 2631-6129
    DOI 10.1093/jbi/wbaa067
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: How to Minimize Patient Anxiety From Screening Mammography.

    Pai, Vidya R / Rebner, Murray

    Journal of breast imaging

    2024  Volume 3, Issue 5, Page(s) 603–606

    Abstract: Anxiety has been portrayed by the media and some organizations and societies as one of the harms of mammography. However, one experiences anxiety in multiple different medical tests that are undertaken, including screening examinations; it is not unique ... ...

    Abstract Anxiety has been portrayed by the media and some organizations and societies as one of the harms of mammography. However, one experiences anxiety in multiple different medical tests that are undertaken, including screening examinations; it is not unique to mammography. Some may argue that because this anxiety is transient, the so-called harm is potentially overstated, but for some women the anxiety is significant. Anxiety can increase or decrease the likelihood of obtaining a screening mammogram. There are multiple ways that anxiety associated with screening mammography can be diminished, including before, during, and after the examination. These include simple measures such as patient education, improved communication, being aware of the patient's potential discomfort and addressing it, validating the patient's anxiety as well as providing the patient with positive factual data that can easily be implemented in every breast center. More complex interventions include altering the breast center environment with multisensory stimulation, reorganization of patient flow to minimize wait times, and relaxation techniques including complementary and alternative medicine. In this article we will review the literature on measures that can be taken to minimize anxiety that would maximize the likelihood of a woman obtaining an annual screening mammogram.
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ISSN 2631-6129
    ISSN (online) 2631-6129
    DOI 10.1093/jbi/wbab057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Corrigendum to: Breast Cancer Screening Recommendations: African American Women Are at a Disadvantage.

    Rebner, Murray / Pai, Vidya R

    Journal of breast imaging

    2024  Volume 3, Issue 2, Page(s) 262

    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ISSN 2631-6129
    ISSN (online) 2631-6129
    DOI 10.1093/jbi/wbab011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Direct Prepectoral Implant-Based Reconstruction in the COVID Era.

    Vidya, Raghavan

    Plastic and reconstructive surgery

    2020  Volume 147, Issue 1, Page(s) 161e–162e

    MeSH term(s) Breast Implantation ; Breast Implants ; COVID-19 ; Humans ; Mammaplasty ; Risk Factors ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-10-07
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 208012-6
    ISSN 1529-4242 ; 0032-1052 ; 0096-8501
    ISSN (online) 1529-4242
    ISSN 0032-1052 ; 0096-8501
    DOI 10.1097/PRS.0000000000007473
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Application of seaweed extracts to mitigate biotic and abiotic stresses in plants.

    Raja, Bharath / Vidya, Radhakrishnan

    Physiology and molecular biology of plants : an international journal of functional plant biology

    2023  Volume 29, Issue 5, Page(s) 641–661

    Abstract: Agriculture sector is facing a lot of constraints such as climate change, increasing population and the use of chemicals, and fertilizers which have significant influence on sustainability. The excessive usage of chemical fertilizers and pesticides has ... ...

    Abstract Agriculture sector is facing a lot of constraints such as climate change, increasing population and the use of chemicals, and fertilizers which have significant influence on sustainability. The excessive usage of chemical fertilizers and pesticides has created a significant risk to humans, animals, plants, and the environment. To reduce the dependency on chemical fertilizers and pesticides a biological-based alternative is required. Seaweeds are essential marine resources that contain bioactive compounds and they have several uses in agriculture. The use of seaweed extracts in agriculture can mitigate stress, enhance nutrient efficiency, and boost plant growth. The use of seaweed extracts and their components activate several signaling pathways and defense-related genes/enzymes. In this review, an attempt has been made to explain how seaweed extracts and their bioactive components induce tolerance and promote growth under stress conditions.
    Language English
    Publishing date 2023-05-23
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2487126-6
    ISSN 0974-0430 ; 0971-5894
    ISSN (online) 0974-0430
    ISSN 0971-5894
    DOI 10.1007/s12298-023-01313-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Prediction of intermediate band in Ti/V doped γ-In

    Jebasty, R Mariyal / Sjåstad, Anja Olafsen / Vidya, R

    RSC advances

    2022  Volume 12, Issue 3, Page(s) 1331–1340

    Abstract: Materials with an intermediate energy band (IB) introduced in the forbidden gap are viable alternatives to tandem configurations of solar cells for increasing the photon-conversion efficiency. One of the aspiring designs proposed for the intermediate ... ...

    Abstract Materials with an intermediate energy band (IB) introduced in the forbidden gap are viable alternatives to tandem configurations of solar cells for increasing the photon-conversion efficiency. One of the aspiring designs proposed for the intermediate band concept is hyperdoped (Ti, V):In
    Language English
    Publishing date 2022-01-06
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d0ra08132a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Current Global Trends in Prepectoral Breast Reconstruction.

    Taj, Saima / Chandavarkar, Ravi / Vidya, Raghavan

    Medicina (Kaunas, Lithuania)

    2024  Volume 60, Issue 3

    Abstract: Implant-based breast reconstruction (IBBR) is the most frequently performed procedure for breast reconstruction following mastectomy, which involves the surgical placement of breast implants. The approach to breast reconstruction can be divided into two ... ...

    Abstract Implant-based breast reconstruction (IBBR) is the most frequently performed procedure for breast reconstruction following mastectomy, which involves the surgical placement of breast implants. The approach to breast reconstruction can be divided into two main categories, namely prepectoral breast reconstruction (PPBR) and subpectoral breast reconstruction (SPBR), based on the implant plan and placement technique. In recent years, there has been a significant surge in the popularity of prepectoral implant-based breast reconstruction, where the implants are positioned above the chest muscle, as opposed to beneath it in the subpectoral approach. However, despite this growing preference, there is a lack of comprehensive data regarding the national trends in the utilization of this technique, thus necessitating further investigation. This narrative review aims to ascertain the current global patterns linked to prepectoral breast reconstruction and elucidate the considerations surrounding patient and implant selection, reconstructive techniques, the utilization of meshes in prepectoral reconstruction, the ensuing outcomes and complications, the ramifications of radiotherapy, and the potential advantages of integrating fat infiltration into the implementation of this technique in breast reconstruction with a focus on published papers in last five years. Conclusion: Prepectoral breast reconstruction has emerged as an appropriate surgical option for individuals seeking breast reconstruction. This development can be attributed to the recent progress made in implant technology, which has significantly enhanced the outcomes of this procedure. Additionally, advancements in mastectomy techniques, autologous fat grafting, and the use of acellular dermal matrices (ADMs) have also played a vital role in improving the aesthetic results of prepectoral breast reconstruction. As a result, the significance and effectiveness of this technique in the field of breast reconstruction have been firmly established, making it an essential component of the overall armamentarium available to plastic surgeons for breast reconstruction purposes.
    MeSH term(s) Humans ; Female ; Mastectomy/methods ; Breast Neoplasms/surgery ; Pectoralis Muscles/surgery ; Mammaplasty/methods ; Breast Implantation/methods ; Retrospective Studies
    Language English
    Publishing date 2024-03-03
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina60030431
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Therapeutic Potential of Cucumis melo (L.) Fruit Extract and Its Silver Nanopartciles Against DEN-Induced Hepatocellular Cancer in Rats

    Vidya, R. / Kalaivani, K. / Amudha, P.

    Applied biochemistry and biotechnology. 2022 Jan., v. 194, no. 1

    2022  

    Abstract: Biosynthesized silver nanoparticles have a wide range of biological activities and using nanoparticles as one of the novel approaches in cancer therapy. In this present research work, the anti-cancer efficacy of Cucumis melo fruit extract and its silver ... ...

    Abstract Biosynthesized silver nanoparticles have a wide range of biological activities and using nanoparticles as one of the novel approaches in cancer therapy. In this present research work, the anti-cancer efficacy of Cucumis melo fruit extract and its silver nanoparticles was explored. Wistar rats were divided into six groups and hepatic cancer was induced with 0.01% DEN (diethylnitrosamine) through drinking water for 16 weeks. Cyclophosphamide was given as the standard drug at the dose of 50 mg/kg body weight. Hematological parameters showed a decrease in the levels of hemoglobin (Hb), packed cell volume (PCV), red blood cells (RBC), mean corpuscular volume (MCV), mean corpuscular Hb (MCH), mean corpuscular Hb concentration (MCHC), and platelets (PLTS) levels except white blood cell (WBC) in DEN-induced cancer animals. Significant alterations in the hematological parameters were observed after treatment which indicate the protective effect of Cucumis melo fruit on the hemopoietic system. The structural integrity of the cells has been damaged in cancer-induced animals, and this results in cytoplasmic leakage of enzyme into the blood stream, leads to the elevated levels of these enzymes in blood with subsequent fall in the tissues. Hence, the levels of liver function markers such as AST ALT, ALP, LDH, GGT, and 5’NT were significantly elevated in serum and the liver of cancer-induced rats. The levels of serum tumor markers, viz., alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA), elevated in rats induced with DEN, which then were reduced following Cucumis melo fruit treatment, indicating the anti-cancer activity of the drug. Histological evaluation of the liver and kidney was also performed to authenticate the present work. Treatment with crude extract and silver nanoparticles of Cucumis melo fruit indicates that Cucumis melo fruit could have exerted its protective effect.
    Keywords Cucumis melo ; antigens ; antineoplastic activity ; biosynthesis ; biotechnology ; blood flow ; blood serum ; body weight ; cancer therapy ; cyclophosphamide ; diethylnitrosamine ; fruit extracts ; fruits ; hemoglobin ; hepatoma ; histology ; kidneys ; leukocytes ; liver ; liver function ; nanosilver ; protective effect
    Language English
    Dates of publication 2022-01
    Size p. 368-381.
    Publishing place Springer US
    Document type Article
    ZDB-ID 392344-7
    ISSN 0273-2289
    ISSN 0273-2289
    DOI 10.1007/s12010-021-03765-9
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Chemopreventive and Therapeutic Efficacy of Enhalus acoroides against Diethylnitrosamine Induced Hepatocellular Carcinoma in Wistar Albino Rats.

    Amudha, P / Jayalakshmi, M / Vidya, R / Poojitha, B N

    Applied biochemistry and biotechnology

    2022  Volume 195, Issue 4, Page(s) 2597–2617

    Abstract: Hepatocellular carcinoma is the second most cause of death among the various cancers worldwide. Recent research searching an alternative therapy for cancer treatment without or less side effects. Many studies indicated the beneficial effects of Enhalus ... ...

    Abstract Hepatocellular carcinoma is the second most cause of death among the various cancers worldwide. Recent research searching an alternative therapy for cancer treatment without or less side effects. Many studies indicated the beneficial effects of Enhalus acoroides. There has been no scientific validation on antioxidant and chemopreventive potential of ethanolic extract E. acoroides against hepatoma. To assess the hepatoprotective activity of E. acoroides (EEEA) against DEN-induced hepatoma using Wistar albino rats. Animals were distributed into five groups, each containing six rats. To Group I - control rats - normal saline given. Groups II, III, IV and V rats were injection of DEN at a dose of 100 mg/kg body weight i.p. to induce liver cancer. At the commencement of 6th week, Group III rats supplemented with EEEA at a dose of 200 mg/kg body weight/day upto 16 weeks. Group IV rats supplemented with EEEA for 1 week before the administration of DEN and continued till the sixteenth week. Group V supplementation of silymarin at a dose of 100 mg/kg body weight at the beginning of 6th week after the injection of DEN and continued upto 16 weeks and considered as positive control rats. The efficiency of E. acoroides for its antioxidant hepatoprotective and activity evaluated in rats against DEN-induced liver damage. The hepatoprotective ability of EEEA at a dose of 200 mg/kg was examined against DEN at a dose of 100 mg/kg/b.w. induced hepatotoxicity and analysed by evaluating serum liver and kidney marker levels, lipid profile (TG, HDL, LDL and total cholesterol) and serum tumour markers (DNA, RNA, AFP and CEA). Supplementation of EEEA to DEN treated rats was determined by evaluating various antioxidant biomarkers (SOD, CAT, GPx, GSH, Vit E and Vit C). Histopathological studies and morphometric gross analysis were also support the consequences of this study. A significant improvement of antioxidant defence and declined MDA levels within the serum of EEEA treated animals compared to the DEN-induced hepatoma. The supplementation of EEEA declined the serum liver, kidney and serum tumour marker levels and lipid profile as comparatively to Group I rats. The histopathological changes were changed on supplementation of EEEA demonstrating its protecting effects on hepatocytes as comparatively to Group I rats. Our significances recognized that crude extract (ethanol) of E. acoroides revealed a potential impact against DEN-induced hepatoma and assists as a superior choice for chemopreventive treatments.
    MeSH term(s) Animals ; Rats ; Carcinoma, Hepatocellular/chemically induced ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/prevention & control ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Diethylnitrosamine/toxicity ; Liver Neoplasms/chemically induced ; Liver Neoplasms/drug therapy ; Liver Neoplasms/prevention & control ; Rats, Wistar ; Liver/pathology ; Body Weight ; Lipids/pharmacology
    Chemical Substances Antioxidants ; Diethylnitrosamine (3IQ78TTX1A) ; Lipids
    Language English
    Publishing date 2022-02-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392344-7
    ISSN 1559-0291 ; 0273-2289
    ISSN (online) 1559-0291
    ISSN 0273-2289
    DOI 10.1007/s12010-022-03832-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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