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  1. Article: Inflammatory Pseudotumor of the Pancreas Mimicking a Pancreatic Neoplasm.

    Baião, José Miguel / Martins, Rui Miguel / Correia, João Guardado / Jordão, Daniel / Vieira Caroço, Teresa / Caetano Oliveira, Rui / Agostinho, Paulo Gil / Ferrão, Henrique

    Case reports in gastroenterology

    2019  Volume 13, Issue 2, Page(s) 245–252

    Abstract: A 78-year-old woman was admitted to our hospital with a pancreatic tumor, incidentally discovered in an abdominal ultrasound exam. She was asymptomatic and without any previous personal pathological condition. The computed tomography (CT) and the ... ...

    Abstract A 78-year-old woman was admitted to our hospital with a pancreatic tumor, incidentally discovered in an abdominal ultrasound exam. She was asymptomatic and without any previous personal pathological condition. The computed tomography (CT) and the magnetic resonance imaging (MRI) scan showed a mass lesion of 4 cm in diameter, located in the pancreatic body, conditioning the invasion of the splenic vein. The patient was admitted to surgery. During the laparotomy, we found a tumoral lesion highly suspicious of pancreatic neoplasia located in the transition of the head/body of the pancreas, with an invasion of the portal vein and several peri-regional lymph nodes. We performed biopsies of the pancreatic mass and lymphadenectomy of the peri-regional pancreatic lymph nodes. Histological analysis found an inflammatory pseudotumor of the head/body of the pancreas, without signals of malign epithelial neoplasm and also without criteria for immunoglobulin G4-related disease. During the follow-up, a PET/CT and MRI confirmed that the pancreatic lesion had disappeared without any treatment. Inflammatory pseudotumor of the pancreas is a rare entity not fully understood. Despite this, the administration of corticosteroids and immunosuppressive therapy could be taken into consideration as the disease carries a risk.
    Language English
    Publishing date 2019-06-13
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2440540-1
    ISSN 1662-0631
    ISSN 1662-0631
    DOI 10.1159/000501064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Entzündlicher Pseudotumor der Bauchspeicheldrüse, der eine Pankreasneoplasie vortäuscht

    Baião, José Miguel / Martins, Rui Miguel / Correia, João Guardado / Jordão, Daniel / Vieira Caroço, Teresa / Caetano Oliveira, Rui / Agostinho, Paulo Gil / Ferrão, Henrique

    Karger Kompass Onkologie

    2019  Volume 6, Issue 4, Page(s) 234–238

    Abstract: Eine 78-jährige Frau wurde mit einem Pankreastumor, der als Zufallsbefund im Rahmen einer abdominalen Ultraschalluntersuchung entdeckt worden war, in unsere Klinik eingewiesen. Sie war asymptomatisch und hatte keine Vorerkrankungen. Die ... ...

    Institution Surgical Department, Instituto Português de Oncologia de Coimbra, Coimbra, Portugal Pathology Department, Centro de Diagnóstico Anatomo-Patológico (CEDAP), Coimbra, Portugal Radiology Department, Instituto Português de Oncologia de Coimbra, Coimbra, Portugal
    Abstract Eine 78-jährige Frau wurde mit einem Pankreastumor, der als Zufallsbefund im Rahmen einer abdominalen Ultraschalluntersuchung entdeckt worden war, in unsere Klinik eingewiesen. Sie war asymptomatisch und hatte keine Vorerkrankungen. Die Computertomographie (CT) und die Magnetresonanztomographie (MRT) zeigten einen Herdbefund von 4 cm Durchmesser im Pankreaskörper, der den Weg für eine Invasion der Milzvene bereitete. Daraufhin wurde eine Operation anberaumt. Bei der Laparotomie fand sich eine Tumorläsion, die hochverdächtig auf eine Pankreasneoplasie am Übergang vom Pankreaskopf zum -körper mit Invasion der Portalvene und mehrerer regionärer peripankreatischer Lymphknoten war. Wir entnahmen Biopsien der Pankreasläsion und führten eine Lymphadenektomie der regionären peripankreatischen Lymphknoten durch. Die histologische Untersuchung ergab einen entzündlichen Pseudotumor im Pankreaskopf/-körper ohne Hinweise auf eine maligne epitheliale Neoplasie und auch ohne die Kriterien für eine Immunglobulin-G4-assoziierte Erkrankung. Bei den im Rahmen der Nachsorge durchgeführten PET/CT- und MRT-Untersuchungen zeigte sich, dass die Pankreasläsion ohne jegliche Therapie verschwunden war. Der entzündliche Pseudotumor der Bauchspeicheldrüse ist eine seltene Entität, die noch nicht vollständig geklärt ist. Dennoch kann die Gabe von Kortikosteroiden und Immunsuppressiva erwogen werden, da die Krankheit mit einem Risiko behaftet ist.
    Keywords Inflammatory pseudotumor ; Pancreatic cancer ; Pancreatectomy ; IgG4-related disease ; Myofibroblastic spindle cells
    Language German
    Publishing date 2019-12-12
    Publisher S. Karger GmbH
    Publishing place Freiburg, Germany
    Document type Article
    Note Erfahrungen aus der Praxis
    ZDB-ID 3050162-3
    ISSN 2296-5386 ; 2296-5416
    ISSN (online) 2296-5386
    ISSN 2296-5416
    DOI 10.1159/000504614
    Database Karger publisher's database

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  3. Article: Inflammatory Pseudotumor of the Pancreas Mimicking a Pancreatic Neoplasm

    Baião, José Miguel / Martins, Rui Miguel / Correia, João Guardado / Jordão, Daniel / Vieira Caroço, Teresa / Caetano Oliveira, Rui / Agostinho, Paulo Gil / Ferrão, Henrique

    Case Reports in Gastroenterology

    2019  Volume 13, Issue 2, Page(s) 245–252

    Abstract: A 78-year-old woman was admitted to our hospital with a pancreatic tumor, incidentally discovered in an abdominal ultrasound exam. She was asymptomatic and without any previous personal pathological condition. The computed tomography (CT) and the ... ...

    Institution Surgical Department, Instituto Português de Oncologia de Coimbra, Coimbra, Portugal
    Pathology Department, Centro de Diagnóstico Anatomo-Patológico (CEDAP), Coimbra, Portugal
    Radiology Department, Instituto Português de Oncologia de Coimbra, Coimbra, Portugal
    Abstract A 78-year-old woman was admitted to our hospital with a pancreatic tumor, incidentally discovered in an abdominal ultrasound exam. She was asymptomatic and without any previous personal pathological condition. The computed tomography (CT) and the magnetic resonance imaging (MRI) scan showed a mass lesion of 4 cm in diameter, located in the pancreatic body, conditioning the invasion of the splenic vein. The patient was admitted to surgery. During the laparotomy, we found a tumoral lesion highly suspicious of pancreatic neoplasia located in the transition of the head/body of the pancreas, with an invasion of the portal vein and several peri-regional lymph nodes. We performed biopsies of the pancreatic mass and lymphadenectomy of the peri-regional pancreatic lymph nodes. Histological analysis found an inflammatory pseudotumor of the head/body of the pancreas, without signals of malign epithelial neoplasm and also without criteria for immunoglobulin G4-related disease. During the follow-up, a PET/CT and MRI confirmed that the pancreatic lesion had disappeared without any treatment. Inflammatory pseudotumor of the pancreas is a rare entity not fully understood. Despite this, the administration of corticosteroids and immunosuppressive therapy could be taken into consideration as the disease carries a risk.
    Keywords Inflammatory pseudotumor ; Pancreatic cancer ; Pancreatectomy ; IgG4-related disease ; Myofibroblastic spindle cells
    Language English
    Publishing date 2019-06-13
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Single Case ; This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC).
    ZDB-ID 2440540-1
    ISSN 1662-0631 ; 1662-0631
    ISSN (online) 1662-0631
    ISSN 1662-0631
    DOI 10.1159/000501064
    Database Karger publisher's database

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