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Article ; Online: Intracoronary pressures to predict myocardial viability in patients with ischemic left ventricular dysfunction.

Marchese, Nicola / Barbato, Emanuele / Di Gioia, Giuseppe / Stanislao, Mario / Valle, Guido / Copetti, Massimiliano / Pellegrini, Giorgia / Vigna, Carlo

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

2022 Volume 99, Issue 2, Page(s) 271–279

Abstract: To investigate the role of intracoronary pressure parameters in the assessment of viability in the myocardium subtending a significant coronary stenosis. In patients with ischemic left ventricular dysfunction, the presence of myocardial viability is ... ...

Abstract	To investigate the role of intracoronary pressure parameters in the assessment of viability in the myocardium subtending a significant coronary stenosis. In patients with ischemic left ventricular dysfunction, the presence of myocardial viability is related to the expected benefits derived from coronary revascularization. Intracoronary pressure wire-based measurements were performed in 64 coronary lesions of ≥50% stenosis severity of 59 patients with postischemic left ventricular dysfunction, segmental left ventricular wall motion abnormalities, and substantial viability in the myocardial territory subtending the investigated stenotic coronaries, defined as the percent summed rest score in the target territory (%SRS
MeSH term(s)	Coronary Angiography ; Coronary Stenosis/complications ; Coronary Stenosis/diagnostic imaging ; Coronary Vessels ; Fractional Flow Reserve, Myocardial ; Humans ; Myocardium ; Predictive Value of Tests ; Severity of Illness Index ; Treatment Outcome ; Ventricular Dysfunction, Left/diagnostic imaging ; Ventricular Dysfunction, Left/etiology
Language	English
Publishing date	2022-01-18
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1459995-8
ISSN	1522-726X ; 1522-1946
ISSN (online)	1522-726X
ISSN	1522-1946
DOI	10.1002/ccd.30065
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Zs.A 1226: Show issues

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Article: Low GFR amplifies the association between coronary three-vessel disease and all-cause mortality

Piscitelli, Pamela / D'Errico, Maria M. / Mirijello, Antonio / Santoliquido, Mariateresa / Salvatori, Mauro / Vigna, Carlo / Marchese, Nicola / Vendemiale, Gianluigi / Copetti, Massimiliano / Pontremoli, Roberto / De Cosmo, Salvatore A.

The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University Nutrition, metabolism, and cardiovascular diseases. 2022 Feb., v. 32, no. 2

2022

Abstract: Three vessels disease (3VD) has been associated with worse prognosis and higher mortality. Chronic kidney disease (CKD) is an independent risk factor for premature death, mostly due to coronary artery disease (CAD).We aim to examine the prognostic impact ...

Abstract	Three vessels disease (3VD) has been associated with worse prognosis and higher mortality. Chronic kidney disease (CKD) is an independent risk factor for premature death, mostly due to coronary artery disease (CAD).We aim to examine the prognostic impact of 3VD on all-cause mortality in a cohort of high cardiovascular risk subjects undergoing coronary angiography (CA) and to explore whether low eGFR (<60 ml/min/1.73 m²) modulates the risk of all-cause mortality associated to 3VD.One-thousand-seventeen subjects (759 M, mean age 68.4 ± 11 years) consecutive subjects undergoing CA from 2016 to 2018 were evaluated. Subjects were classified according to the severity of CAD as follows: group “three vessels disease” (3VD), and “no three vessels disease” (No 3VD). Serum creatinine was measured to estimate glomerular filtration rate (eGFR). The whole population was divided into 4 groups (A, B, C, D), according to the presence/absence of low eGFR and/or 3VD. One-hundred-fourteen deaths occurred (median follow-up:44 months). The risk of death in subjects with 3VD was almost 2-time higher than subject without 3VD (adjusted HR = 1.61; 95% CI 1.094–2.373, p = 0.0157). Among 4 subgroups, subjects with low eGFR and 3VD (Group D) had the highest risk of death (adjusted HR = 3.881; 95% CI 2.256–6.676, p < 0.0001).Low eGFR significantly amplifies the risk of all-cause mortality associated to 3VD. Our results strengthen the role of kidney disease as a risk multiplier for cardiovascular and all-cause mortality and highlight the need to prevent its onset and progression.
Keywords	angiography ; blood serum ; coronary artery disease ; creatinine ; death ; glomerular filtration rate ; kidney diseases ; metabolism ; mortality ; multipliers ; nutrition ; prognosis ; risk factors
Language	English
Dates of publication	2022-02
Size	p. 402-409.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	1067704-5
ISSN	0939-4753
ISSN	0939-4753
DOI	10.1016/j.numecd.2021.09.036
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Zs.A 3149: Show issues

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Article ; Online: Albuminuria improves R

Piscitelli, Pamela / D'Errico, Maria Maddalena / Vigna, Carlo / Marchese, Nicola / Lamacchia, Olga / Fontana, Andrea / Copetti, Massimiliano / Pontremoli, Roberto / Mirijello, Antonio / De Cosmo, Salvatore A

Nutrition, metabolism, and cardiovascular diseases : NMCD

2023 Volume 33, Issue 8, Page(s) 1591–1598

Abstract: Background and aims: The CHA: Methods and results: Prospective, monocentric, observational study, evaluating a subset of 737 subjects consecutively undergoing to coronary angiography at Coronary Unit of Scientific Institute "Casa Sollievo della ... ...

Abstract	Background and aims: The CHA Methods and results: Prospective, monocentric, observational study, evaluating a subset of 737 subjects consecutively undergoing to coronary angiography at Coronary Unit of Scientific Institute "Casa Sollievo della Sofferenza" from June 2016 to December 2018. The presence of albuminuria was significantly associated with all-cause mortality (p < 0.0001). Any one-point increase of Alb-R Conclusions: The addition of albuminuria to R
MeSH term(s)	Humans ; Risk Factors ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/complications ; Prospective Studies ; Albuminuria/diagnosis ; Atrial Fibrillation/epidemiology ; Heart Disease Risk Factors ; Risk Assessment ; Stroke/epidemiology
Language	English
Publishing date	2023-05-13
Publishing country	Netherlands
Document type	Observational Study ; Journal Article
ZDB-ID	1067704-5
ISSN	1590-3729 ; 0939-4753
ISSN (online)	1590-3729
ISSN	0939-4753
DOI	10.1016/j.numecd.2023.05.014
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Article ; Online: Inappropriate shock and percutaneous cardiac intervention: A lesson to learn in the cath lab.

Di Stolfo, Giuseppe / Mastroianno, Sandra / Massaro, Raimondo / Vigna, Carlo / Russo, Aldo / Potenza, Domenico Rosario

Pacing and clinical electrophysiology : PACE

2019 Volume 42, Issue 11, Page(s) 1496–1498

Abstract: Coronary disease is a common condition in patients affected by heart failure with severely reduced ejection fraction (HFrEF). This condition represents an indication for implantable cardioverter defibrillator (ICD) in order to reduce the risk of sudden ... ...

Abstract	Coronary disease is a common condition in patients affected by heart failure with severely reduced ejection fraction (HFrEF). This condition represents an indication for implantable cardioverter defibrillator (ICD) in order to reduce the risk of sudden death related to arrhythmias. Nevertheless, inappropriate shocks are associated with worse quality of life, hospitalization, and death. We present the case of an inappropriate shock related to percutaneous coronary intervention during the insertion and advancement of the guidewire into the left anterior descending artery (LAD) in a patient with an ICD. Physicians' awareness about the clinical implication of noise arising during a coronary procedure is very important in patients with an ICD or pacemaker, to avoid inappropriate shock or pacing inhibition and to raise the possibility of lead implantation in or helix protrusion into the coronary lumen.
MeSH term(s)	Defibrillators, Implantable ; Equipment Failure ; Humans ; Intraoperative Complications/prevention & control ; Male ; Middle Aged ; Percutaneous Coronary Intervention
Language	English
Publishing date	2019-08-25
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	424437-0
ISSN	1540-8159 ; 0147-8389
ISSN (online)	1540-8159
ISSN	0147-8389
DOI	10.1111/pace.13784
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Zs.A 1466: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Cerebral Infarcts After Coronary Angiography and Percutaneous Coronary Intervention: A Prospective Propensity-Score-Adjusted Comparison of Right Radial, Left Radial, and Femoral Approaches.

Marchese, Nicola / Copetti, Massimiliano / Inchingolo, Vincenzo / Popolizio, Teresa / Fontana, Andrea / Simeone, Annalisa / Vigna, Carlo

Cardiovascular revascularization medicine : including molecular interventions

2019 Volume 21, Issue 7, Page(s) 882–887

Abstract: Background: New cerebral infarcts (CIs) detected at magnetic resonance imaging (MRI) are reported after cardiac procedures. Clinical and procedural aspects are implicated as potential causal factors. The aim of this study was to evaluate the incidence ... ...

Abstract	Background: New cerebral infarcts (CIs) detected at magnetic resonance imaging (MRI) are reported after cardiac procedures. Clinical and procedural aspects are implicated as potential causal factors. The aim of this study was to evaluate the incidence of new CIs after coronary angiography and percutaneous coronary intervention according to the arterial access site. Methods: 180 patients undergoing elective coronary angiography were studied with cerebral MRI the day before and the day after the procedure. Unadjusted and propensity score (PS) analyses were performed comparing the occurrence of CIs in right radial (RR), left radial (LR) and transfemoral (TF) access groups. Results: New CIs were observed in 14 patients (7.8% of the total sample, one with neurological sequelae). CIs were detected in 15.5% vs 4.9% vs 3.3% of RR, LR and TF groups, respectively (p = .026). In PS adjusted analyses, the RR approach was associated with more CIs compared with the TF approach (odds ratio [OR] estimate from logistic regression adjusted by PS quartiles: 0.158; 95% confidence interval: 0.031 to 0.814; p = .027) and the LR approach (OR: 0.266; 95% confidence interval: 0.066 to 1.080; p = .064). In a secondary analysis, a comparison of RR vs non-RR approach (TF + LR) was performed, showing that post-procedural CIs were more frequent in the RR group (OR: 0.170; 95% confidence interval: 0.050 to 0.574; p = .004). Conclusions: Our study suggests that the RR approach may be associated with a higher rate of new CIs after coronary angiography compared with LR and TF approaches.
MeSH term(s)	Aged ; Aged, 80 and over ; Catheterization, Peripheral/adverse effects ; Cerebral Infarction/diagnostic imaging ; Cerebral Infarction/epidemiology ; Coronary Angiography/adverse effects ; Diffusion Magnetic Resonance Imaging ; Female ; Femoral Artery ; Humans ; Incidence ; Italy/epidemiology ; Male ; Middle Aged ; Percutaneous Coronary Intervention/adverse effects ; Prevalence ; Propensity Score ; Punctures ; Radial Artery ; Risk Assessment ; Risk Factors
Language	English
Publishing date	2019-11-12
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	2212113-4
ISSN	1878-0938 ; 1553-8389
ISSN (online)	1878-0938
ISSN	1553-8389
DOI	10.1016/j.carrev.2019.11.010
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Zs.A 5562: Show issues

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Article ; Online: Mitral Perivalvular Leak after Blunt Chest Trauma: A Rare Cause of Severe Subacute Mitral Regurgitation.

Marchese, Nicola / Facciorusso, Antonio / Vigna, Carlo

Texas Heart Institute journal

2015 Volume 42, Issue 6, Page(s) 579–581

Abstract: Blunt chest trauma is a very rare cause of valve disorder. Moreover, mitral valve involvement is less frequent than is aortic or tricuspid valve involvement, and the clinical course is usually acute. In the present report, we describe the case of a 49- ... ...

Abstract	Blunt chest trauma is a very rare cause of valve disorder. Moreover, mitral valve involvement is less frequent than is aortic or tricuspid valve involvement, and the clinical course is usually acute. In the present report, we describe the case of a 49-year-old man with a perivalvular mitral injury that became clinically manifest one year after a violent, nonpenetrating chest injury. This case is atypical in regard to the valve involved (isolated mitral damage), the injury type (perivalvular leak in the absence of subvalvular abnormalities), and the clinical course (interval of one year between trauma and symptoms).
MeSH term(s)	Accidental Falls ; Echocardiography, Transesophageal ; Heart Injuries/diagnosis ; Heart Injuries/etiology ; Heart Injuries/physiopathology ; Heart Injuries/surgery ; Heart Valve Prosthesis Implantation ; Humans ; Male ; Middle Aged ; Mitral Valve/diagnostic imaging ; Mitral Valve/injuries ; Mitral Valve/physiopathology ; Mitral Valve/surgery ; Mitral Valve Annuloplasty ; Mitral Valve Insufficiency/diagnosis ; Mitral Valve Insufficiency/etiology ; Mitral Valve Insufficiency/physiopathology ; Mitral Valve Insufficiency/surgery ; Severity of Illness Index ; Time Factors ; Treatment Outcome ; Wounds, Nonpenetrating/diagnosis ; Wounds, Nonpenetrating/etiology ; Wounds, Nonpenetrating/physiopathology ; Wounds, Nonpenetrating/surgery
Language	English
Publishing date	2015-12
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	604761-0
ISSN	1526-6702 ; 0730-2347
ISSN (online)	1526-6702
ISSN	0730-2347
DOI	10.14503/THIJ-14-4439
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Zs.A 1452: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 484: Show issues

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Article ; Online: CHA2DS2-VASc and R2CHA2DS2-VASc scores predict mortality in high cardiovascular risk population.

D'Errico, Maria Maddalena / Piscitelli, Pamela / Mirijello, Antonio / Santoliquido, Mariateresa / Salvatori, Mauro / Vigna, Carlo / Vendemiale, Gianluigi / Lamacchia, Olga / Fontana, Andrea / Copetti, Massimiliano / Pontremoli, Roberto / De Cosmo, Salvatore A

European journal of clinical investigation

2022 Volume 52, Issue 11, Page(s) e13830

Abstract: Background: The CHA: Methods: In this single-centre prospective observational study, conducted at the Research Hospital 'Casa Sollievo della Sofferenza' between June 2016 and December 2018, 1017 CV patients at high risk of undergoing coronary ... ...

Abstract	Background: The CHA Methods: In this single-centre prospective observational study, conducted at the Research Hospital 'Casa Sollievo della Sofferenza' between June 2016 and December 2018, 1017 CV patients at high risk of undergoing coronary angiography were enrolled. Results: CHA₂DS₂-VASc and R Conclusions: The CHA₂DS₂-VASc and R
MeSH term(s)	Atrial Fibrillation/complications ; Cardiovascular Diseases/epidemiology ; Heart Disease Risk Factors ; Humans ; Risk Assessment ; Risk Factors ; Stroke/etiology
Language	English
Publishing date	2022-07-11
Publishing country	England
Document type	Journal Article ; Observational Study
ZDB-ID	186196-7
ISSN	1365-2362 ; 0014-2972 ; 0960-135X
ISSN (online)	1365-2362
ISSN	0014-2972 ; 0960-135X
DOI	10.1111/eci.13830
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Zs.A 677: Show issues

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Article: Trattamento dell'infarto acuto in provincia di Foggia: esiste anche l'angioplastica primaria.

Vigna, Carlo / Fanelli, Raffaele

Giornale italiano di cardiologia (2006)

2009 Volume 10, Issue 1, Page(s) 64; author reply 64

Title translation	Treatment of acute infarction in the province of Foggia: primary angioplasty exists, too.
MeSH term(s)	Angioplasty, Balloon, Coronary ; Coronary Care Units ; Humans ; Italy ; Myocardial Infarction/drug therapy ; Myocardial Infarction/therapy ; Thrombolytic Therapy
Language	Italian
Publishing date	2009-01
Publishing country	Italy
Document type	Comment ; Letter
ZDB-ID	2272414-X
ISSN	1972-6481 ; 1827-6806
ISSN (online)	1972-6481
ISSN	1827-6806
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Article ; Online: Low eGFR and albuminuria independently predict all-cause mortality in high-risk subjects undergoing coronary arteriography.

D'Errico, Maria Maddalena / Piscitelli, Pamela / Mirijello, Antonio / Santoliquido, Mariateresa / Massa, Valentina / Salvatori, Mauro / Vigna, Carlo / Vendemiale, Gianluigi / Aucella, Filippo / Pontremoli, Roberto / De Cosmo, Salvatore A

Internal and emergency medicine

2021 Volume 17, Issue 3, Page(s) 695–701

Abstract: Individuals with Chronic Kidney Disease (CKD) are at high risk for cardiovascular morbidity and mortality. The aim of this study was to examine the relationship between renal dysfunction and all-cause mortality in a sample of subjects undergoing coronary ...

Abstract	Individuals with Chronic Kidney Disease (CKD) are at high risk for cardiovascular morbidity and mortality. The aim of this study was to examine the relationship between renal dysfunction and all-cause mortality in a sample of subjects undergoing coronary angiography (CA). We evaluated 1017 subjects who consecutively underwent CA. Glomerular filtration rate (eGFR) was estimated by CKD-EPI and urinary albumin excretion reported as urinary albumin-to-creatinine ratio. Vital status was ascertained by interrogating the Italian Health Card Database. One-thousand-seventeen subjects (759 M/258F) were enrolled into the study from 2016 to 2018. One-hundred-fourteen deaths occurred during a median follow-up of 44 months. The whole population was divided in two subgroups according to the presence/absence of low eGFR (i.e. < 60 ml/min/1.73 m
MeSH term(s)	Albumins ; Albuminuria ; Coronary Angiography ; Female ; Glomerular Filtration Rate ; Humans ; Male ; Renal Insufficiency, Chronic ; Risk Factors
Chemical Substances	Albumins
Language	English
Publishing date	2021-10-05
Publishing country	Italy
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2454173-4
ISSN	1970-9366 ; 1828-0447
ISSN (online)	1970-9366
ISSN	1828-0447
DOI	10.1007/s11739-021-02851-4
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Article ; Online: Low GFR amplifies the association between coronary three-vessel disease and all-cause mortality.

Piscitelli, Pamela / D'Errico, Maria M / Mirijello, Antonio / Santoliquido, Mariateresa / Salvatori, Mauro / Vigna, Carlo / Marchese, Nicola / Vendemiale, Gianluigi / Copetti, Massimiliano / Pontremoli, Roberto / De Cosmo, Salvatore A

Nutrition, metabolism, and cardiovascular diseases : NMCD

2021 Volume 32, Issue 2, Page(s) 402–409

Abstract: Background and aim: Three vessels disease (3VD) has been associated with worse prognosis and higher mortality. Chronic kidney disease (CKD) is an independent risk factor for premature death, mostly due to coronary artery disease (CAD). We aim to examine ...

Abstract	Background and aim: Three vessels disease (3VD) has been associated with worse prognosis and higher mortality. Chronic kidney disease (CKD) is an independent risk factor for premature death, mostly due to coronary artery disease (CAD). We aim to examine the prognostic impact of 3VD on all-cause mortality in a cohort of high cardiovascular risk subjects undergoing coronary angiography (CA) and to explore whether low eGFR (<60 ml/min/1.73 m Methods and results: One-thousand-seventeen subjects (759 M, mean age 68.4 ± 11 years) consecutive subjects undergoing CA from 2016 to 2018 were evaluated. Subjects were classified according to the severity of CAD as follows: group "three vessels disease" (3VD), and "no three vessels disease" (No 3VD). Serum creatinine was measured to estimate glomerular filtration rate (eGFR). The whole population was divided into 4 groups (A, B, C, D), according to the presence/absence of low eGFR and/or 3VD. One-hundred-fourteen deaths occurred (median follow-up:44 months). The risk of death in subjects with 3VD was almost 2-time higher than subject without 3VD (adjusted HR = 1.61; 95% CI 1.094-2.373, p = 0.0157). Among 4 subgroups, subjects with low eGFR and 3VD (Group D) had the highest risk of death (adjusted HR = 3.881; 95% CI 2.256-6.676, p < 0.0001). Conclusions: Low eGFR significantly amplifies the risk of all-cause mortality associated to 3VD. Our results strengthen the role of kidney disease as a risk multiplier for cardiovascular and all-cause mortality and highlight the need to prevent its onset and progression.
MeSH term(s)	Aged ; Coronary Angiography ; Coronary Artery Disease/diagnostic imaging ; Creatinine ; Glomerular Filtration Rate ; Humans ; Middle Aged ; Prognosis ; Renal Insufficiency, Chronic/diagnosis ; Risk Factors
Chemical Substances	Creatinine (AYI8EX34EU)
Language	English
Publishing date	2021-10-09
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1067704-5
ISSN	1590-3729 ; 0939-4753
ISSN (online)	1590-3729
ISSN	0939-4753
DOI	10.1016/j.numecd.2021.09.036
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