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  1. Article ; Online: Sports Activity Done Five Days before PET/CT Results in Augmented FDG uptake in Skeletal Muscles

    Prathamesh Joshi / Vikram Lele

    Iranian Journal of Nuclear Medicine, Vol 20, Iss 2, Pp 30-

    2012  Volume 33

    Abstract: Increased metabolic activity in muscle secondary to excessive muscle activity during the uptake phase and shortly before FDG injection is a known phenomenon. We present FDG PET/CT findings in a young male, known case of carcinoma maxilla His scan showed ... ...

    Abstract Increased metabolic activity in muscle secondary to excessive muscle activity during the uptake phase and shortly before FDG injection is a known phenomenon. We present FDG PET/CT findings in a young male, known case of carcinoma maxilla His scan showed diffuse increased metabolic activity in multiple skeletal muscle groups. There was history of unaccustomed, strenuous sports activity of skiing five days before the scan and no history of other known factors known to enhance skeletal muscle FDG uptake. After carefully eliminating all other known factors causing augmented FDG uptake in muscles, we attributed this uptake to be the persistent effect of sports activity of skiing. Though the exact mechanism remains unclear, our case suggests; the effect of exercise causing increased FDG uptake in skeletal muscles may persist for longer period than previously proposed and reported.
    Keywords FDG Uptake in Skeletal Muscle ; FDG PET/CT ; FDG Uptake Phase ; Exercise Induced FDG Uptake ; Medical physics. Medical radiology. Nuclear medicine ; R895-920 ; Medicine (General) ; R5-920 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Subject code 796
    Language English
    Publishing date 2012-01-01T00:00:00Z
    Publisher Tehran University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: An unusual case of extraosseous accumulation of bone scan tracer in a renal calculus - demonstration by SPECT-CT

    Prathamesh Vijay Joshi / Vikram Lele / Rozil Gandhi

    Journal of Clinical Imaging Science, Vol 2, Iss 1, Pp 4-

    2012  Volume 4

    Abstract: Extraosseous localization of radioisotope, used in bone scan, in a variety of physiological and pathological conditions is a well-known phenomenon. The causes of extraosseous accumulation of bone-seeking radiotracers should be kept in mind when bone- ... ...

    Abstract Extraosseous localization of radioisotope, used in bone scan, in a variety of physiological and pathological conditions is a well-known phenomenon. The causes of extraosseous accumulation of bone-seeking radiotracers should be kept in mind when bone-imaging studies are reviewed to avoid incorrect interpretations. We report an extremely rare occurrence of extraosseous accumulation of bone scintigraphy tracer in a renal calculus, in a patient with adenocarcinoma of prostate, that was demonstrated by Single Photon Emission Computed Tomography and Computed Tomography (SPECT-CT) fusion imaging.
    Keywords Bone scan ; extraosseous uptake ; renal calculus ; SPECT-CT ; 99mTc-MDP ; Medicine (General) ; R5-920 ; Medicine ; R
    Language English
    Publishing date 2012-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Lymphadenopathy resulting from acute toxoplasmosis mimicking relapse of non-Hodgkin′s lymphoma on fluorodeoxyglucose positron emission tomography/computed tomography

    Prathamesh Joshi / Vikram Lele / Pravin Mahajan

    Journal of Cancer Research and Therapeutics, Vol 8, Iss 1, Pp 126-

    2012  Volume 128

    Abstract: We report a case documenting fluorodeoxyglucose (FDG) accumulation in cervical, supraclavicular and axillary lymph nodes resulting from acute toxoplasmosis. A 50-year-old Indian female with history of non-Hodgkin′s lymphoma (NHL) of left breast, ... ...

    Abstract We report a case documenting fluorodeoxyglucose (FDG) accumulation in cervical, supraclavicular and axillary lymph nodes resulting from acute toxoplasmosis. A 50-year-old Indian female with history of non-Hodgkin′s lymphoma (NHL) of left breast, postchemotherapy status, was found to have hypermetabolic right cervical, supraclavicular and axillary lymph nodes on a surveillance FDG positron emission tomography/computed tomography (PET/CT) scan. Her previous two PET/CT scans were unremarkable with no evidence of metabolically active disease. Therefore, a differential diagnosis of relapse of NHL versus infectious/inflammatory pathology was raised in the report. Biopsy of axillary lymph node demonstrated features characteristic of toxoplasmosis. The serological test results were also compatible with acute toxoplasmosis infection. Infective and inflammatory diseases are known to accumulate FDG, resulting in false positives for malignancy. This case demonstrates lymph nodal toxoplasmosis as a potential cause of false positive FDG PET/CT findings in patients with known malignancy and highlights the importance of histopathological and laboratory correlation for the accurate interpretation of FDG PET/CT scans.
    Keywords FDG PET/CT ; infection ; lymph nodes ; NHL ; relapse ; toxoplasmosis ; Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282 ; Internal medicine ; RC31-1245 ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2012-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Honda Sign On 18-FDG PET/CT in a Case of Lymphoma Leading to Incidental Detection of Sacral Insufficiency Fracture

    Prathamesh Joshi / Vikram Lele / Rozil Gandhi / Anil Parab

    Journal of Clinical Imaging Science, Vol 2, Iss 1, Pp 29-

    2012  Volume 29

    Abstract: Sacral insufficiency fracture (SIF) is an important and treatable cause of low back pain in at-risk groups and the elderly. We report rare demonstration of ′Honda sign′ in fluoro-deoxy-glucose positron emission tomography-computed tomography (FDG PET-CT) ...

    Abstract Sacral insufficiency fracture (SIF) is an important and treatable cause of low back pain in at-risk groups and the elderly. We report rare demonstration of ′Honda sign′ in fluoro-deoxy-glucose positron emission tomography-computed tomography (FDG PET-CT) in a case of lymphoma, which led to incidental diagnosis of SIF. Honda sign, which is classically described in bone scans in cases of SIF, was found in FDG PET-CT in our case. This suggests SIF should be suspected when similar FDG uptake pattern is encountered and may help in early detection and management of SIF.
    Keywords Bone scan ; fluorodeoxyglucose ; honda sign ; positron emission tomography-computed tomography ; sacral insufficiency fracture ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Language English
    Publishing date 2012-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Comparison of 68Ga-DOTA-NaI3-Octreotide/tyr3-octreotate positron emission tomography/computed tomography and contrast-enhanced computed tomography in localization of tumors in multiple endocrine neoplasia 1 syndrome

    Virendra Patil / Manjunath Goroshi / Hina Shah / Gaurav Malhotra / Priya Hira / Vijaya Sarathi / Vikram Lele / Swati Jadhav / Anurag Lila / Tushar Bandgar / Nalini Shah

    World Journal of Nuclear Medicine, Vol 19, Iss 02, Pp 99-

    2020  Volume 105

    Abstract: The optimum imaging modality for the screening of multiple endocrine neoplasia type 1 (MEN1)-associated tumors is not well established. Here, we compare the performance of contrast-enhanced CT (CECT) versus 68Ga DOTA-NOC/TATE PET/CT in MEN1 patients. The ...

    Abstract The optimum imaging modality for the screening of multiple endocrine neoplasia type 1 (MEN1)-associated tumors is not well established. Here, we compare the performance of contrast-enhanced CT (CECT) versus 68Ga DOTA-NOC/TATE PET/CT in MEN1 patients. The retrospective case record study is conducted at a tertiary health-care center. Thirty-four patients, who have undergone both CECT and 68Ga DOTA-NOC/TATE PET, were included in the analysis. CECT had higher per-lesion sensitivity than 68Ga DOTA-NOC/TATE PET/CT for the detection of parathyroid lesions, (82.6% vs. 24.6%, P < 0.001). 68Ga DOTA-NOC/TATE PET/CT had higher per-lesion sensitivity than CECT for the detection of metastases (85% vs. 47.5%, P < 0.001) and gastrinomas (90% vs. 10%, P = 0.003). When combined use of the two imaging modalities is compared to CECT alone (63.7% vs. 93.1%, P = 0.00012) and 68Ga-DOTA-NOC/TATE PET/CT alone (74.1% vs. 93.1%, P = 0.0057), it provided significantly higher per-lesion sensitivity for the detection of gastroenteropancreatic neuroendocrine tumors (GEP-NETs). 68Ga-DOTA-NOC/TATE PET was more sensitive for the detection of gastrinomas and metastases than CECT, whereas it was less sensitive for the detection of parathyroid lesions than CECT. The combined use of both the imaging modalities significantly increases the sensitivity for detection of GEP-NETs.
    Keywords 68ga-dota-nai3-octreotide/tyr3-octreotate positron emission tomography/computed tomography ; contrast enhanced computed tomography ; gastrointestinal-pancreatic neuroendocrine tumor ; multiple endocrine neoplasia type 1 imaging ; multiple endocrine neoplasia type 1 syndrome ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Subject code 610
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Stomach metastasis of breast carcinoma mimicking primary gastric neoplasm on fluorodeoxy glucose-positron emission tomography-computed tomography

    Prathamesh Joshi / Vikram Lele / Reetu Jain / Shaila Khubchandani / Shraddha Sinhasan

    Indian Journal of Medical and Paediatric Oncology, Vol 34, Iss 2, Pp 128-

    2013  Volume 129

    Abstract: We present fluorodeoxy glucose positron emission tomography-computed tomography (FDG-PET/CT) findings in a case of breast carcinoma. The PET/CT findings in this case were suspicious of second primary neoplasm in the stomach. However, on endoscopic biopsy, ...

    Abstract We present fluorodeoxy glucose positron emission tomography-computed tomography (FDG-PET/CT) findings in a case of breast carcinoma. The PET/CT findings in this case were suspicious of second primary neoplasm in the stomach. However, on endoscopic biopsy, the lesion was found to be stomach metastasis of breast carcinoma with estrogen receptor positivity. Stomach is a rare site of breast carcinoma metastasis. Our case suggests that it is difficult to distinguish a stomach metastasis of breast cancer from a primary gastric cancer on the basis of clinical and imaging features. However, this differential diagnosis must be kept in mind and it is important to make such distinction because of its implications on patient management.
    Keywords Breast carcinoma ; estrogen receptor positive ; fluorodeoxy glucose positron emission tomography-computed tomography ; stomach metastasis ; second primary neoplasm ; Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282 ; Internal medicine ; RC31-1245 ; Medicine ; R ; Pediatrics ; RJ1-570
    Subject code 616
    Language English
    Publishing date 2013-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Indian Council of Medical Research consensus document for the management of colorectal cancer

    Bhawna Sirohi / Shailesh V Shrikhande / Benjamin Perakath / Digumarti Raghunandharao / Pramod Kumar Julka / Vikram Lele / Arvind Chaturvedi / Ambakumar Nandakumar / M Ramadwar / Vikram Bhatia / Rohin Mittal / Tanvir Kaur / Deepak Kumar Shukla / Goura Kishor Rath

    Indian Journal of Medical and Paediatric Oncology, Vol 35, Iss 3, Pp 192-

    2014  Volume 196

    Keywords Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282 ; Internal medicine ; RC31-1245 ; Medicine ; R ; Pediatrics ; RJ1-570
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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