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Article ; Online: Transjugular intrahepatic portosystemic shunt safety in patients on the liver transplantation waiting list. Risks and benefits.

Vilatobá, M

Revista de gastroenterologia de Mexico (English)

2023 Volume 89, Issue 1, Page(s) 1–3

MeSH term(s)	Humans ; Portasystemic Shunt, Transjugular Intrahepatic/adverse effects ; Liver Transplantation ; Waiting Lists ; Liver Cirrhosis ; Risk Assessment
Language	English
Publishing date	2023-05-08
Publishing country	Mexico
Document type	Editorial
ZDB-ID	2828765-4
ISSN	2255-534X ; 2255-534X
ISSN (online)	2255-534X
ISSN	2255-534X
DOI	10.1016/j.rgmxen.2023.02.005
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Article ; Online: Mucormycosis in Liver Allograft Following Transplant for Secondary Biliary Cirrhosis.

Parmentier, Catherine / Cruz-Martínez, Rodrigo / Quintero-Quintero, Marco J / Vilatobá, Mario

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation

2024 Volume 22, Issue 4, Page(s) 314–317

Abstract: Mucormycosis, a group of opportunistic mycoses caused by Mucorales, present a significant threat to immunocompromised patients. In this report, we present the case of a 57-year-old male patient who underwent liver transplant for secondary biliary ... ...

Abstract	Mucormycosis, a group of opportunistic mycoses caused by Mucorales, present a significant threat to immunocompromised patients. In this report, we present the case of a 57-year-old male patient who underwent liver transplant for secondary biliary cirrhosis following inadvertent bile duct injury. Despite initial satisfactory postoperative evolution, the patient developed fever, and imaging revealed a suspicious lesion. Preliminary culture growth suggested a filamentous fungus, leading to initiation of liposomal amphotericin B. However, the lesion progressed, and a surgical debridement was necessary. During surgery, involvement of the liver dome and diaphragm was observed, and a nonanatomical hepatectomy was performed. Despite efforts, the patient's condition deteriorated, ultimately resulting in multiple organ failure and mortality. This case emphasizes the challenging nature of mucormycosis in livertransplant recipients.
MeSH term(s)	Humans ; Male ; Mucormycosis/diagnosis ; Mucormycosis/microbiology ; Mucormycosis/immunology ; Mucormycosis/drug therapy ; Mucormycosis/etiology ; Middle Aged ; Liver Transplantation/adverse effects ; Antifungal Agents/therapeutic use ; Immunocompromised Host ; Fatal Outcome ; Liver Cirrhosis, Biliary/surgery ; Liver Cirrhosis, Biliary/microbiology ; Liver Cirrhosis, Biliary/diagnosis ; Treatment Outcome ; Opportunistic Infections/microbiology ; Opportunistic Infections/immunology ; Opportunistic Infections/diagnosis ; Opportunistic Infections/drug therapy ; Debridement ; Allografts ; Hepatectomy ; Amphotericin B/therapeutic use ; Amphotericin B/administration & dosage ; Multiple Organ Failure/etiology ; Multiple Organ Failure/microbiology
Language	English
Publishing date	2024-04-20
Publishing country	Turkey
Document type	Case Reports ; Journal Article
ZDB-ID	2396778-X
ISSN	2146-8427 ; 1304-0855
ISSN (online)	2146-8427
ISSN	1304-0855
DOI	10.6002/ect.2023.0142
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Article ; Online: First two cases of domino liver transplantation in Mexico.

Vilatobá, M / González-Duarte, A / Cruz-Martínez, R / García-Juárez, I / Leal-Villalpando, R P

Revista de gastroenterologia de Mexico (English)

2022 Volume 87, Issue 3, Page(s) 386–388

MeSH term(s)	Humans ; Liver Neoplasms ; Liver Transplantation ; Mexico
Language	English
Publishing date	2022-05-23
Publishing country	Mexico
Document type	Case Reports
ZDB-ID	2828765-4
ISSN	2255-534X ; 2255-534X
ISSN (online)	2255-534X
ISSN	2255-534X
DOI	10.1016/j.rgmxen.2022.05.003
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Article ; Online: What to do if the liver is not right? A unique scenario for liver transplantation in adults.

Vilatoba, Mario / Carpinteyro-Espin, Paulina / Eckhoff, Devin E

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

2020 Volume 20, Issue 8, Page(s) 2277–2279

MeSH term(s)	Adult ; Humans ; Liver ; Liver Transplantation ; Living Donors
Language	English
Publishing date	2020-07-19
Publishing country	United States
Document type	Editorial
ZDB-ID	2060594-8
ISSN	1600-6143 ; 1600-6135
ISSN (online)	1600-6143
ISSN	1600-6135
DOI	10.1111/ajt.16160
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Article ; Online: Postoperative liver function tests can predict anastomotic dysfunction after bile duct injury repair.

Sánchez-Morales, Germán / Castro, Emma / Domínguez-Rosado, Ismael / Vilatoba, Mario / Contreras, Alan / Mercado, Miguel

Updates in surgery

2022 Volume 74, Issue 3, Page(s) 937–944

Abstract: Liver function tests help in the follow-up of postoperative patients with iatrogenic bile duct injury. There is not clear evidence regarding their predictive role on anastomosis dysfunction. We describe our experience with postoperative liver function ... ...

Abstract	Liver function tests help in the follow-up of postoperative patients with iatrogenic bile duct injury. There is not clear evidence regarding their predictive role on anastomosis dysfunction. We describe our experience with postoperative liver function tests and a predictive model of long-term patency after repair. This is retrospective cohort study of patients with bilioenteric anastomosis for bile duct injury and their long-term follow-up. A binomial logistic regression model was performed to ascertain the effects of the grade of bile duct injury and liver function test in the postoperative period. A total of 329 patients were considered for the analysis. In the logistic regression model two predictor variables were statistically significant for anastomosis stenosis: type of bilioenteric anastomosis and alkaline phosphatase levels. A ROC curve analysis was made for alkaline phosphatase with an area under the curve of 0.758 (95% CI 0.67-0.84). A threshold of 323 mg/dL was established (OR 6.0, 95% CI 2.60-13.83) with a sensitivity of 75%, specificity of 67%, PPV of 20%, NPV of 96%, PLR of 2.27 and NLR of 0.37. Increased alkaline phosphatase (above 323 mg/dL) after the fourth operative week was found to be a predictor of long-term dysfunction.
MeSH term(s)	Alkaline Phosphatase ; Anastomosis, Surgical/adverse effects ; Bile Duct Diseases/surgery ; Bile Ducts/injuries ; Bile Ducts/surgery ; Humans ; Liver Function Tests ; Postoperative Complications/diagnosis ; Postoperative Complications/etiology ; Postoperative Period ; Retrospective Studies
Chemical Substances	Alkaline Phosphatase (EC 3.1.3.1)
Language	English
Publishing date	2022-04-12
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2572692-4
ISSN	2038-3312 ; 2038-131X
ISSN (online)	2038-3312
ISSN	2038-131X
DOI	10.1007/s13304-022-01275-9
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Article ; Online: Liver transplantation in a patient with metastatic neuroendocrine tumor: A first report in Mexico.

Vilatobá, M / Hurtado-Gómez, S / García-Juárez, I / Huitzil-Melendez, D / Gamboa-Domínguez, A

Revista de gastroenterologia de Mexico (English)

2019 Volume 84, Issue 3, Page(s) 414–416

Title translation	Trasplante hepático en tumor neuroendocrino metastásico, primer reporte en México.
MeSH term(s)	Adult ; Female ; Humans ; Liver Neoplasms/secondary ; Liver Neoplasms/surgery ; Liver Transplantation ; Mexico ; Neuroendocrine Tumors/secondary ; Neuroendocrine Tumors/surgery
Language	Spanish
Publishing date	2019-06-27
Document type	Case Reports ; Letter
ISSN	2255-534X
ISSN (online)	2255-534X
DOI	10.1016/j.rgmx.2018.09.002
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Article ; Online: Posttransplantation diabetes mellitus after liver transplant and the impact of family history of diabetes in a Mexican cohort.

Fernández-Ramírez, A / Olivas-Martinez, A / Ruiz-Manriquez, J / Kauffman-Ortega, E / Moctezuma-Velázquez, C / Marquez-Guillen, E / Contreras, A G / Vilatobá, M / González-Flores, E / Cruz-Martínez, R / Flores-García, N C / García-Juárez, I

Revista de gastroenterologia de Mexico (English)

2023

Abstract: Introduction and aims: Posttransplantation diabetes mellitus (PTDM) is a serious long-term complication that has a negative impact on graft and patient survival. The purpose of the present study was to describe the incidence of PTDM in a Mexican cohort ... ...

Abstract	Introduction and aims: Posttransplantation diabetes mellitus (PTDM) is a serious long-term complication that has a negative impact on graft and patient survival. The purpose of the present study was to describe the incidence of PTDM in a Mexican cohort and evaluate its association with a previous family history of diabetes (FHD). Methods: A retrospective single-center cohort study was conducted on patients undergoing liver transplantation (LT). The primary outcome was time from LT to PTDM. The diagnosis of PTDM was established using the ADA criteria. A mediation analysis that used adjusted Cox regression models and considered pretransplant prediabetes a mediator was performed, to determine the total effect and direct effect of FHD on PTDM. Results: A total of 152 patients were included, with a median follow-up time of 41 months; 19.2% (n = 29) had pretransplant diabetes. During the follow-up time, 15% of patients developed PTDM (n = 23), with an incidence rate of 4.71 cases/100 person-years. PTDM was significantly higher in patients with FHD, compared with those with no FHD (8.72 cases/100 person-years vs 2.04 cases/100 person-years, respectively; p = 0.001). The adjusted hazard ratio of PTDM for FHD was 4.14 (95% CI 1.60-10.7), p = 0.005) and 3.48 (95% CI 1.35-9.01, p = 0.010), when further controlled for pretransplant prediabetes. Conclusion: The occurrence of PTDM was similar to that reported in most international studies. As with type 2 diabetes, family history plays an important role in the development of PTDM, even after accounting for pretransplant prediabetes. Patients with FHD should undergo a stricter metabolic program.
Language	English
Publishing date	2023-10-17
Publishing country	Mexico
Document type	Journal Article
ZDB-ID	2828765-4
ISSN	2255-534X ; 2255-534X
ISSN (online)	2255-534X
ISSN	2255-534X
DOI	10.1016/j.rgmxen.2023.06.002
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Article ; Online: Liver transplantation is beneficial regardless of cirrhosis stage or acute-on-chronic liver failure grade: A single-center experience.

Cervantes-Alvarez, Eduardo / Vilatoba, Mario / Limon-de la Rosa, Nathaly / Mendez-Guerrero, Osvely / Kershenobich, David / Torre, Aldo / Navarro-Alvarez, Nalu

World journal of gastroenterology

2022 Volume 28, Issue 40, Page(s) 5881–5892

Abstract: Background: Liver transplantation for the most critically ill remains controversial; however, it is currently the only curative treatment option.: Aim: To assess immediate posttransplant outcomes and compare the short (1 year) and long-term (6 years) ...

Abstract	Background: Liver transplantation for the most critically ill remains controversial; however, it is currently the only curative treatment option. Aim: To assess immediate posttransplant outcomes and compare the short (1 year) and long-term (6 years) posttransplant survival among cirrhotic patients stratified by disease severity. Methods: We included cirrhotic patients undergoing liver transplantation between 2015 and 2019 and categorized them into compensated cirrhosis (CC), decompensated cirrhosis (DC), and acute-on-chronic liver failure (ACLF). ACLF was further divided into severity grades. Our primary outcomes of interest were total days of intensive care unit (ICU) and hospital stay, development of complications and posttransplant survival at 1 and 6 years. Results: 235 patients underwent liver transplantation (CC = 11, DC = 129 and ACLF = 95). Patients with ACLF had a significantly longer hospital stay [8.0 (6.0-13.0) Conclusion: Patients may benefit from liver transplantation regardless of the cirrhosis stage. ACLF patients have a longer hospital stay and frequency of infectious complications; however, excellent, and comparable 1 and 6-year survival rates support their enlisting and transplantation including those with ACLF-3.
MeSH term(s)	Humans ; Acute-On-Chronic Liver Failure/diagnosis ; Acute-On-Chronic Liver Failure/surgery ; Acute-On-Chronic Liver Failure/etiology ; Liver Transplantation/adverse effects ; Retrospective Studies ; Prognosis ; Liver Cirrhosis/complications ; Liver Cirrhosis/surgery
Language	English
Publishing date	2022-11-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	2185929-2
ISSN	2219-2840 ; 1007-9327
ISSN (online)	2219-2840
ISSN	1007-9327
DOI	10.3748/wjg.v28.i40.5881
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Article ; Online: Psychosocial evaluation for liver transplantation: A brief guide for gastroenterologists.

García-Alanís, M / Toapanta-Yanchapaxi, L / Vilatobá, M / Cruz-Martínez, R / Contreras, A G / López-Yáñez, S / Flores-García, N / Marquéz-Guillén, E / García-Juárez, I

Revista de gastroenterologia de Mexico (English)

2021 Volume 86, Issue 2, Page(s) 172–187

Abstract: Liver transplantation is a lifesaving treatment that improves survival and quality of life. The procedure requires adequate transplant candidate selection carried out by a multidisciplinary team. Psychosocial evaluation is a necessary part of recipient ... ...

Title translation	Evaluación psicosocial para trasplante hepático: una guía breve para gastroenterólogos.
Abstract	Liver transplantation is a lifesaving treatment that improves survival and quality of life. The procedure requires adequate transplant candidate selection carried out by a multidisciplinary team. Psychosocial evaluation is a necessary part of recipient selection and its primary aims are to identify problems and psychosocial needs of the patient and his/her family, to improve transplantation outcomes. Different psychosocial conditions are considered risk factors for morbidity and mortality after transplantation. The presence of those factors per se is not an absolute contraindication, thus adequate evaluation promotes equal access to healthcare, improves results, and optimizes resources. The present review provides an overview of and guidelines for the most important psychosocial issues during the pretransplantation phase.
Language	Spanish
Publishing date	2021-03-24
Publishing country	Mexico
Document type	Journal Article ; Review
ZDB-ID	2828765-4
ISSN	2255-534X ; 2255-534X
ISSN (online)	2255-534X
ISSN	2255-534X
DOI	10.1016/j.rgmx.2020.12.001
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Article ; Online: Ovarian Vein to Portal Vein Reconstruction: Another Option in Liver Transplant With Portal Vein Thrombosis.

Parmentier de León, Catherine / Carpinteyro Espin, Paulina / Quintero Quintero, Marco J / Cruz Martínez, Rodrigo / Vilatoba, Mario

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation

2021 Volume 19, Issue 8, Page(s) 877–879

Abstract: Portal vein thrombosis is a common complication in patients with cirrhosis and a challenge for the transplant team. Not so long ago, portal vein thrombosis was considered an absolute contraindication for liver transplant, but improvements in surgical ... ...

Abstract	Portal vein thrombosis is a common complication in patients with cirrhosis and a challenge for the transplant team. Not so long ago, portal vein thrombosis was considered an absolute contraindication for liver transplant, but improvements in surgical techniques have overcome this problem in many transplant centers around the world. Here, we present the case of a 52-year-old female patient with cirrhosis from a primary biliary cholangitis and a complex portal vein thrombosis. She underwent a deceased donor liver transplant with a Model for End-Stage Liver Disease of 40. The portal thrombosis was handled using a portosystemic shunt from the splenic vein to the left ovarian vein, which was visualized on a computed tomography scan performed as part of the study protocol. The donor was a 52-year-old woman with brain death secondary to a vascular cerebral accident. A caval replacement technique was used with no complications during surgery. For the portal anastomosis, the dilated left ovarian vein was carefully dissected and brought through the lesser sac, behind the stomach, to obtain a suitable length. An end-to-end anastomosis of the graft portal vein to the left ovarian vein was performed with a 6-0 Prolene running suture. An abdominal computed tomography scan was performed 6 months after liver transplant showing patency of portal vein and no anastomotic defects, and after 24 months of follow-up the patient is in good clinical condition with normal laboratory values and Doppler ultrasonography with no vascular anomalies and adequate portal flow. To our knowledge, the use of a spleno-ovarian shunt has not been reported as an alternative for portal reconstruction in a case of thrombosis.
MeSH term(s)	End Stage Liver Disease/etiology ; Female ; Humans ; Liver Cirrhosis/complications ; Liver Diseases/complications ; Liver Transplantation/adverse effects ; Liver Transplantation/methods ; Living Donors ; Middle Aged ; Portal Vein/diagnostic imaging ; Portal Vein/surgery ; Severity of Illness Index ; Thrombosis/etiology ; Treatment Outcome ; Venous Thrombosis/diagnostic imaging ; Venous Thrombosis/etiology ; Venous Thrombosis/surgery
Language	English
Publishing date	2021-06-03
Publishing country	Turkey
Document type	Case Reports
ZDB-ID	2396778-X
ISSN	2146-8427 ; 1304-0855
ISSN (online)	2146-8427
ISSN	1304-0855
DOI	10.6002/ect.2020.0429
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