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  1. Book ; Online: Artificial Intelligence

    Osaba, Eneko / Villar, Esther / Lobo, Jesús L / Laña, Ibai

    Latest Advances, New Paradigms and Novel Applications

    (Artificial Intelligence ; 5)

    2021  

    Series title Artificial Intelligence ; 5
    Keywords Artificial intelligence ; deep learning, ai, feature extraction, condition monitoring, innovation, power quality
    Language English
    Size 1 electronic resource (158 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English
    HBZ-ID HT030644984
    ISBN 9781839623899 ; 1839623896
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Swarm Intelligence : Recent Advances, New Perspectives and Applications

    Del Ser, Javier / Villar, Esther / Osaba, Eneko

    2019  

    Keywords Artificial intelligence
    Size 1 electronic resource (128 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021045074
    ISBN 9781839680007 ; 1839680008
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Pourfour du Petit syndrome after medullary thyroid carcinoma surgery.

    González Villar, Esther / Jiménez, Cortes María / Olmos Alemán, María / Ayo-Martín, Óscar

    Endocrinologia, diabetes y nutricion

    2021  Volume 68, Issue 5, Page(s) 366–367

    MeSH term(s) Adult ; Carcinoma, Neuroendocrine/surgery ; Female ; Humans ; Mydriasis ; Syndrome ; Thyroid Neoplasms/surgery
    Language English
    Publishing date 2021-09-02
    Publishing country Spain
    Document type Case Reports ; Letter
    ISSN 2530-0180
    ISSN (online) 2530-0180
    DOI 10.1016/j.endien.2021.08.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pourfour du Petit syndrome after medullary thyroid carcinoma surgery.

    González Villar, Esther / Jiménez, Cortes María / Olmos Alemán, María / Ayo-Martín, Óscar

    Endocrinologia, diabetes y nutricion

    2020  Volume 68, Issue 5, Page(s) 366–367

    Title translation Síndrome de Pourfour du Petit tras cirugía de carcinoma medular de tiroides.
    MeSH term(s) Adult ; Carcinoma, Neuroendocrine/surgery ; Female ; Humans ; Mydriasis/etiology ; Syndrome ; Thyroid Neoplasms/surgery
    Language Spanish
    Publishing date 2020-06-15
    Publishing country Spain
    Document type Case Reports ; Letter
    ISSN 2530-0180
    ISSN (online) 2530-0180
    DOI 10.1016/j.endinu.2020.03.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Observational retrospective analysis of vaccination against SARS-CoV-2 and seizures: VACCI-COVID registry.

    Martinez-Fernandez, Isabel / Sanchez-Larsen, Alvaro / Gonzalez-Villar, Esther / Martínez-Martín, Álvaro / von Quednow, Enzo / Del Valle-Pérez, Jose Antonio / Andrés-López, Alberto / Restrepo-Carvajal, Laura Carolina / Cuenca-Juan, Fernando / Ballesta-García, Marina / Sopelana, David

    Epilepsy & behavior : E&B

    2022  Volume 134, Page(s) 108808

    Abstract: Background: We aimed to assess the risk of developing new-onset seizures or seizure decompensations in people with epilepsy (PWE) associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines.: Methods: A retrospective ... ...

    Abstract Background: We aimed to assess the risk of developing new-onset seizures or seizure decompensations in people with epilepsy (PWE) associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines.
    Methods: A retrospective observational study in a tertiary hospital was conducted. Clinical records of all patients attended because of seizures or epilepsy at outpatient clinics, emergency department, or admitted to our hospital from January to December 2021 were reviewed, including patients older than 16 years who received some dose of coronavirus disease 2019 (COVID-19) vaccines.
    Results: A total of 418 vaccinated PWE were analyzed: 6.2% presented an increase in seizure frequency and 1% reported different seizure types during the next month after vaccination. However, 61.5% had another possible cause for this decompensation. Having monthly seizures (1-3/month) was the only associated risk factor (OR 4.9, p < 0.001) while being seizure free > 1 year had a protective role (OR 0.36, p = 0.019). Patients with epileptic encephalopathies or a history of COVID-19 infection were not at increased risk of seizure decompensation. Besides this, 15 patients presented new-onset seizures within the first month post-vaccination, mean time from vaccination 15 ± 8 days, 67% after the second dose. Again, 53.3% had another possible trigger for seizures. Eight debuted with status epilepticus or cluster of seizures.
    Conclusions: A small proportion of PWE (6.2%) had an increase in seizure frequency after COVID-19 vaccination and 15 patients had new-onset seizures during the first month after vaccination, though another reason for seizure exacerbation was identified in 61.5% and 53.3%, respectively. Severe acute respiratory syndrome COVID-19 vaccines appear to have little impact on the generation or decompensation of seizures.
    MeSH term(s) COVID-19 ; COVID-19 Vaccines ; Epilepsy ; Humans ; Registries ; Retrospective Studies ; SARS-CoV-2 ; Seizures ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-06-22
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 2010587-3
    ISSN 1525-5069 ; 1525-5050
    ISSN (online) 1525-5069
    ISSN 1525-5050
    DOI 10.1016/j.yebeh.2022.108808
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5289: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Influence of the COVID-19 outbreak in people with epilepsy: Analysis of a Spanish population (EPICOVID registry).

    Sanchez-Larsen, Alvaro / Gonzalez-Villar, Esther / Díaz-Maroto, Inmaculada / Layos-Romero, Almudena / Martínez-Martín, Álvaro / Alcahut-Rodriguez, Cristian / Grande-Martin, Alberto / Sopelana-Garay, David

    Epilepsy & behavior : E&B

    2020  Volume 112, Page(s) 107396

    Abstract: Background: The aim of this study was to have a better understanding of the influence of the coronavirus disease 2019 (COVID-19) pandemic in people with epilepsy (PWE) and to assess whether there have been changes in seizure control during the current ... ...

    Abstract Background: The aim of this study was to have a better understanding of the influence of the coronavirus disease 2019 (COVID-19) pandemic in people with epilepsy (PWE) and to assess whether there have been changes in seizure control during the current COVID-19 outbreak, exploring the possible causes thereof.
    Methods: This is an observational, retrospective study based on prospective data collection of 100 successive patients who attended an epilepsy outpatient clinic either face-to-face or telephonically during the months of the COVID-19 outbreak and national state of emergency.
    Results: One hundred patients were included, 52% women, mean age 42.4 years. During the COVID-19 period, 27% of the patients presented an increase of >50% of seizure frequency. An increase of stress/anxiety (odds ratios (OR): 5.78; p = 0.008) and a prior higher seizure frequency (OR: 12.4; p = 0.001) were associated with worsening of seizures. Other risk factors were exacerbation of depression, sleep deprivation, less physical activity, and history of epilepsy surgery. Three patients had status epilepticus (SE) and one a cluster of seizures. Likewise, 9% of patients improved their seizure control. Reduction in stress/anxiety (OR: 0.05; p = 0.03) and recent adjustment of antiepileptics (OR: 0.07; p = 0.01) acted as protecting factors.
    Conclusions: A high proportion of PWE suffered a significant worsening of their seizure control during the months of the COVID-19 pandemic. Emotional distress due to home confinement was the main factor for the change in seizure control. Promoting physical activity and adequate sleep may minimize the potential impact of the pandemic in PWE. Ensuring correct follow-up can prevent decompensation in those PWE at high risk.
    MeSH term(s) Adolescent ; Adult ; Anticonvulsants/therapeutic use ; Anxiety/physiopathology ; Anxiety/psychology ; Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Depression/physiopathology ; Depression/psychology ; Disease Progression ; Epilepsy/drug therapy ; Epilepsy/physiopathology ; Epilepsy/psychology ; Exercise ; Female ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral ; Recurrence ; Registries ; Retrospective Studies ; Risk Factors ; SARS-CoV-2 ; Seizures/physiopathology ; Sleep Deprivation/physiopathology ; Spain ; Status Epilepticus/physiopathology ; Stress, Psychological/physiopathology ; Stress, Psychological/psychology
    Chemical Substances Anticonvulsants
    Keywords covid19
    Language English
    Publishing date 2020-09-07
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 2010587-3
    ISSN 1525-5069 ; 1525-5050
    ISSN (online) 1525-5069
    ISSN 1525-5050
    DOI 10.1016/j.yebeh.2020.107396
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5289: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Influence of the COVID-19 outbreak in people with epilepsy: Analysis of a Spanish population (EPICOVID registry)

    Sanchez-Larsen, Alvaro / Gonzalez-Villar, Esther / Díaz-Maroto, Inmaculada / Layos-Romero, Almudena / Martínez-Martín, Álvaro / Alcahut-Rodriguez, Cristian / Grande-Martin, Alberto / Sopelana-Garay, David

    Epilepsy Behav

    Abstract: BACKGROUND: The aim of this study was to have a better understanding of the influence of the coronavirus disease 2019 (COVID-19) pandemic in people with epilepsy (PWE) and to assess whether there have been changes in seizure control during the current ... ...

    Abstract BACKGROUND: The aim of this study was to have a better understanding of the influence of the coronavirus disease 2019 (COVID-19) pandemic in people with epilepsy (PWE) and to assess whether there have been changes in seizure control during the current COVID-19 outbreak, exploring the possible causes thereof. METHODS: This is an observational, retrospective study based on prospective data collection of 100 successive patients who attended an epilepsy outpatient clinic either face-to-face or telephonically during the months of the COVID-19 outbreak and national state of emergency. RESULTS: One hundred patients were included, 52% women, mean age 42.4 years. During the COVID-19 period, 27% of the patients presented an increase of >50% of seizure frequency. An increase of stress/anxiety (odds ratios (OR): 5.78; p = 0.008) and a prior higher seizure frequency (OR: 12.4; p = 0.001) were associated with worsening of seizures. Other risk factors were exacerbation of depression, sleep deprivation, less physical activity, and history of epilepsy surgery. Three patients had status epilepticus (SE) and one a cluster of seizures. Likewise, 9% of patients improved their seizure control. Reduction in stress/anxiety (OR: 0.05; p = 0.03) and recent adjustment of antiepileptics (OR: 0.07; p = 0.01) acted as protecting factors. CONCLUSIONS: A high proportion of PWE suffered a significant worsening of their seizure control during the months of the COVID-19 pandemic. Emotional distress due to home confinement was the main factor for the change in seizure control. Promoting physical activity and adequate sleep may minimize the potential impact of the pandemic in PWE. Ensuring correct follow-up can prevent decompensation in those PWE at high risk.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #745902
    Database COVID19

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  8. Article ; Online: Influence of the COVID-19 outbreak in people with epilepsy

    Sanchez-Larsen, Alvaro / Gonzalez-Villar, Esther / Díaz-Maroto, Inmaculada / Layos-Romero, Almudena / Martínez-Martín, Álvaro / Alcahut-Rodriguez, Cristian / Grande-Martin, Alberto / Sopelana-Garay, David

    Epilepsy & Behavior

    Analysis of a Spanish population (EPICOVID registry)

    2020  Volume 112, Page(s) 107396

    Keywords Behavioral Neuroscience ; Neurology ; Clinical Neurology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2010587-3
    ISSN 1525-5069 ; 1525-5050
    ISSN (online) 1525-5069
    ISSN 1525-5050
    DOI 10.1016/j.yebeh.2020.107396
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Zs.A 5289: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Genetic Architecture of Ischaemic Strokes after COVID-19 Shows Similarities with Large Vessel Strokes.

    Llucià-Carol, Laia / Muiño, Elena / Cullell, Natalia / Cárcel-Márquez, Jara / Lledós, Miquel / Gallego-Fabrega, Cristina / Martin-Campos, Jesús / Martí-Fàbregas, Joan / Aguilera-Simón, Ana / Planas, Anna M / DeDiego, Marta L / de Felipe Mimbrera, Alicia / Masjuan, Jaime / García-Madrona, Sebastián / Segura, Tomás / González-Villar, Esther / Serrano-Heras, Gemma / Domínguez Mayoral, Ana / Menéndez-Valladares, Paloma /
    Montaner, Joan / Migeotte, Isabelle / Rahmouni, Souad / Darcis, Gilles / Bernardo, David / Rojo, Silvia / Schulte, Eva C / Protzer, Ulrike / Fricke, Lisa / Winter, Christof / Niemi, Mari E K / Cordioli, Mattia / Delgado, Pilar / Fernández-Cadenas, Israel

    International journal of molecular sciences

    2023  Volume 24, Issue 17

    Abstract: We aimed to analyse whether patients with ischaemic stroke (IS) occurring within eight days after the onset of COVID-19 (IS-COV) are associated with a specific aetiology of IS. We used SUPERGNOVA to identify genome regions that correlate between the IS- ... ...

    Abstract We aimed to analyse whether patients with ischaemic stroke (IS) occurring within eight days after the onset of COVID-19 (IS-COV) are associated with a specific aetiology of IS. We used SUPERGNOVA to identify genome regions that correlate between the IS-COV cohort (73 IS-COV cases vs. 701 population controls) and different aetiological subtypes. Polygenic risk scores (PRSs) for each subtype were generated and tested in the IS-COV cohort using PRSice-2 and PLINK to find genetic associations. Both analyses used the IS-COV cohort and GWAS from MEGASTROKE (67,162 stroke patients vs. 454,450 population controls), GIGASTROKE (110,182 vs. 1,503,898), and the NINDS Stroke Genetics Network (16,851 vs. 32,473). Three genomic regions were associated (
    MeSH term(s) Humans ; Stroke/complications ; Stroke/genetics ; Brain Ischemia/complications ; Brain Ischemia/genetics ; COVID-19/complications ; COVID-19/genetics ; Ischemic Stroke/genetics ; Arteries ; Embolic Stroke ; Atherosclerosis
    Language English
    Publishing date 2023-08-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241713452
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: The HLA-B7 allele confers susceptibility to breast cancer in Spanish women.

    Lavado, Rocio / Benavides, Manuel / Villar, Esther / Ales, Inmaculada / Alonso, Antonio / Caballero, Abelardo

    Immunology letters

    2005  Volume 101, Issue 2, Page(s) 223–225

    Abstract: Background: Several HLA alleles are associated with susceptibility or protection in breast cancer. The particular allele varies depending on the geographical region. A study in a small group of Spanish patients using serological methods found an ... ...

    Abstract Background: Several HLA alleles are associated with susceptibility or protection in breast cancer. The particular allele varies depending on the geographical region. A study in a small group of Spanish patients using serological methods found an association with HLA-B7. We undertook a larger study in southern Spain using molecular biology techniques.
    Methods: Genotype variants of HLA class I and II were typed by PCR-SSP in 132 breast cancer patients and 382 healthy controls.
    Results: The frequency of the HLA-B7 allele was increased in the patients compared to the controls (P=0.0019; 95% confidence interval, 1.337-3.409, relative risk=2.135). Bonferroni correction of the P showed it was still significant (P(c)=0.0285).
    Conclusions: These results support previous suggestions that HLA-B7 is associated with the development of breast cancer in our area.
    MeSH term(s) Alleles ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Female ; Genetic Predisposition to Disease/genetics ; HLA-B7 Antigen/genetics ; Humans ; Spain
    Chemical Substances HLA-B7 Antigen
    Language English
    Publishing date 2005-11-15
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 445150-8
    ISSN 1879-0542 ; 0165-2478
    ISSN (online) 1879-0542
    ISSN 0165-2478
    DOI 10.1016/j.imlet.2005.03.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1512: Show issues Location:
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